基于VATA160的前端读出电子学设计

针对核物理实验的读出需求,文中介绍一种具有高集成度、多通道、低功耗、高数据传输速率及较强的扩展性和通用性的前端读出电子学系统。该前端读出电子学系统可以实现对输入信号的传输和采集,保障核物理实验后续数据分析的高效进行。读出电子学系统主要基于VATA160电荷测量专用集成电路(ASIC)和FLASH型现场可编程逻辑门阵列(FPGA)进行设计,采用VATA160电荷测量专用集成电路进行输入信号的处理,并由逻辑控制单元将采集到的数据传输到上位机进行存储分析。最后,对读出系统的基线噪声和工作性能进行测试。结果表明:基线噪声值仅占整个读出系统量程范围的0.026%,噪声干扰小;通道的积分非线性优于0.801%,系统性能优;同时,该系统具有较大的动态范围、集成度以及较强的通用性,对于未来多种核物理实验的研发具有广泛的适应性。

Involvement of mind the gap in the organization of the tracheal apical extracellular matrix in Drosophila and Nilaparvata lugens

The tracheal apical extracellular matrix(aECM)is vital for expansion of the tracheal lumen and supports the normal structure of the lumen to guarantee air entry and circulation in insects.Although it has been found that some cuticular proteins are involved in the organization of the aECM,unidentified factors still exist.Here,we found that mind the gap(Mtg),a predicted chitin-binding protein,is required for the normal formation of the apical chitin matrix of airway tubes in the model holometabolous insect Drosophila melanogaster.Similar to chitin,the Mtg protein was linearly arranged in the tracheal dorsal trunk of the tracheae in Drosophila.Decreased mtg expression in the tracheae seriously affected the viability of larvae and caused tracheal chitin spiral defects in some larvae.Analysis of mtg mutant showed that mtg was required for normal development of tracheae in embryos.Irregular taenidial folds of some mtg mutant embryos were found on either lateral view of tracheal dorsal trunk or internal view of transmission electron microscopy analysis.These abnormal tracheae were not fully filled with gas and accompanied by a reduction in tracheal width,which are characteristic phenotypes of tracheal aECM defects.Furthermore,in the hemimetabolous brown planthopper(BPH)Nilapat'vata lugens,downregulation of NICPAP1-N(a homolog of mtg)also led to the formation of abnormal tracheal chitin spirals and death.These results suggest that mtg and its homolog are involved in the proper organization of the tracheal aECMs in flies and BPH,and that this function may be conserved in insects.

集成芯片硅微条探测器电子读出系统设计

设计了基于VATA460.3专用集成芯片(ASIC)的多通道、低功耗带触发硅微条探测器读出系统,该系统实现了共32路粒子入射信息读出。测试结果表明:该系统各通道基线稳定,等效噪声水平均低于0.17 fC,动态范围可达90 fC。

电视胸腔镜手术的麻醉处理

我院自1999年10月～2001年10月共施行电视胸腔镜手术28例,麻醉效果满意,现报道如下.

Design and evaluation of prototype readout electronics for nuclide detector in Very Large Area Space Telescope

China plans to develop the next generation dark matter particle explorer satellite,referred to as the Very Large Area Space Telescope(VLAST).As an essential step in this process,the prototype design of detectors and electronics for the VLAST is currently underway.The nuclide detector is a core detector in the VLAST.It mainly measures nuclides’charges and distinguishes high-energy gamma rays and electrons.This paper will discuss the prototype readout electronics for the VLAST’s nuclide detector,which accurately measures the charge signal of the photomultiplier tubes using the VATA160 applicationspecific integrated circuit chip;furthermore,we consider a series of critical problems,including radiation-hardening and environment monitoring.The test results show that the system exhibits stable operation,good performance,and good technical indicators.Furthermore,each electronic channel achieves a dynamic range of 0-12.5 pC,the random noise level exceeds 1.6 fC,and the integral nonlinearity exceeds 0.35%.

The antioxidant status in human population based on the concept of prakruthi in Ayurveda

Objective:In the Ayurvedic system of medicine,body constitution(prakruthi) is said to play a vital role in the disease process as well as in its progression.Free radical toxicity is also involved in the etiopathogenesis of many disorders.Hence,in the present study an attempt has been made to correlate the body constitution type and the antioxidant status of that prakruthi.Methods:Healthy volunteers from Manipal University Campus, South Karnataka,India were classified into three main human constitutions(prakruthi) and their possible combinations and their serum total antioxidant activity was determined.Results:There was a significant negative correlation of the total antioxidant status with the pitta prakruthi whereas vata and kapha constitutions showed no significant correlation with the total antioxidant status.Conclusion:Ayurveda classifies each individual based on his/her prakruthi into three categories of Doshas:Vata,Pitta and Kapha(collectively known as Tridoshas ). The three Doshas are fundamental regulatory principles responsible for maintaining organism functioning and manifesting those characteristics typifying each individual,that is,in equilibrium Tridoshas signify health and an imbalance leads to disease.Thus,in this study a significantly decreased antioxidant status in the Pitta group would render them more susceptible to damage by oxidative stress.Hence,we suggest that supplementation with antioxidants of herbal(Ayurvedic) origin to such a group would prove to be beneficial - opening up the arena for pharmacogenomics and customized antioxidant drug administration based on the prakruthi of an individual.

三秽素理论(Ⅰ)

选取印度学者Madhabendranath Pal原著The Tridosha Theory的1～6部分进行编译。蒙医学三体素理论核心内涵源自古代印度阿育吠陀医学三秽素理论。研究发现,三秽素(Vata、Pitta、Kapha)基本概念内涵与蒙医学三体素赫依、希拉、巴达干基本概念内涵高度吻合。通过全面真实地描述三秽素理论,对于蒙印传统医学基础理论的比较研究具有重要的学术价值。

三秽素理论(Ⅱ)

对印度学者Madhabendranath Pal原著The Tridosha Theory第7～9部分内容进行编译。原著者意图通过介绍著名学者用生理学和生物能量学研究方法,阐释阿育吠陀医学三秽素(三体液)理论科学性的观点,试图证明三秽素理论假设是成立的。本文选取此论文进行编译,其目的是为科学实证蒙医学三体素理论假设提供研究思路和示范。