Review on the Fabrication of Surface Functional Structures for Enhancing Bioactivity of Titanium and Titanium Alloy Implants

Titanium and its alloys have been widely applied in many biomedical fields because of its excellent mechanical properties,corrosion resistance and good biocompatibility.However,problems such as rejection,shedding and infection will occur after titanium alloy implantation due to the low biological activity of titanium alloy surface.The structures with specific functions,which can enhance osseointegration and antibacterial properties,are fabricated on the surface of titanium implants to improve the biological activity between the titanium implants and human tissues.This paper presents a comprehensive review of recent developments and applications of surface functional structure in titanium and titanium alloy implants.The applications of surface functional structure on different titanium and titanium alloy implants are introduced,and their manufacturing technologies are summarized and compared.Furthermore,the fabrication of various surface functional structures used for titanium and titanium alloy implants is reviewed and analyzed in detail.Finally,the challenges affecting the development of surface functional structures applied in titanium and titanium alloy implants are outlined,and recommendations for future research are presented.

Design and additive manufacturing of bionic hybrid structure inspired by cuttlebone to achieve superior mechanical properties and shape memory function

Lightweight porous materials with high load-bearing,damage tolerance and energy absorption(EA)as well as intelligence of shape recovery after material deformation are beneficial and critical for many applications,e.g.aerospace,automobiles,electronics,etc.Cuttlebone produced in the cuttlefish has evolved vertical walls with the optimal corrugation gradient,enabling stress homogenization,significant load bearing,and damage tolerance to protect the organism from high external pressures in the deep sea.This work illustrated that the complex hybrid wave shape in cuttlebone walls,becoming more tortuous from bottom to top,creates a lightweight,load-bearing structure with progressive failure.By mimicking the cuttlebone,a novel bionic hybrid structure(BHS)was proposed,and as a comparison,a regular corrugated structure and a straight wall structure were designed.Three types of designed structures have been successfully manufactured by laser powder bed fusion(LPBF)with NiTi powder.The LPBF-processed BHS exhibited a total porosity of 0.042% and a good dimensional accuracy with a peak deviation of 17.4μm.Microstructural analysis indicated that the LPBF-processed BHS had a strong(001)crystallographic orientation and an average size of 9.85μm.Mechanical analysis revealed the LPBF-processed BHS could withstand over 25000 times its weight without significant deformation and had the highest specific EA value(5.32 J·g^(−1))due to the absence of stress concentration and progressive wall failure during compression.Cyclic compression testing showed that LPBF-processed BHS possessed superior viscoelastic and elasticity energy dissipation capacity.Importantly,the uniform reversible phase transition from martensite to austenite in the walls enables the structure to largely recover its pre-deformation shape when heated(over 99% recovery rate).These design strategies can serve as valuable references for the development of intelligent components that possess high mechanical efficiency and shape memory capabilities.

A Hybrid Level Set Optimization Design Method of Functionally Graded Cellular Structures Considering Connectivity

With the continuous advancement in topology optimization and additive manufacturing(AM)technology,the capability to fabricate functionally graded materials and intricate cellular structures with spatially varying microstructures has grown significantly.However,a critical challenge is encountered in the design of these structures–the absence of robust interface connections between adjacent microstructures,potentially resulting in diminished efficiency or macroscopic failure.A Hybrid Level Set Method(HLSM)is proposed,specifically designed to enhance connectivity among non-uniform microstructures,contributing to the design of functionally graded cellular structures.The HLSM introduces a pioneering algorithm for effectively blending heterogeneous microstructure interfaces.Initially,an interpolation algorithm is presented to construct transition microstructures seamlessly connected on both sides.Subsequently,the algorithm enables the morphing of non-uniform unit cells to seamlessly adapt to interconnected adjacent microstructures.The method,seamlessly integrated into a multi-scale topology optimization framework using the level set method,exhibits its efficacy through numerical examples,showcasing its prowess in optimizing 2D and 3D functionally graded materials(FGM)and multi-scale topology optimization.In essence,the pressing issue of interface connections in complex structure design is not only addressed but also a robust methodology is introduced,substantiated by numerical evidence,advancing optimization capabilities in the realm of functionally graded materials and cellular structures.

Functionally graded structure of a nitride-strengthened Mg_(2)Si-based hybrid composite

The ex-situ incorporation of the secondary SiC reinforcement,along with the in-situ incorporation of the tertiary and quaternary Mg_(3)N_(2) and Si_(3)N_(4) phases,in the primary matrix of Mg_(2)Si is employed in order to provide ultimate wear resistance based on the laser-irradiation-induced inclusion of N_(2) gas during laser powder bed fusion.This is substantialized based on both the thermal diffusion-and chemical reactionbased metallurgy of the Mg_(2)Si–SiC/nitride hybrid composite.This study also proposes a functional platform for systematically modulating a functionally graded structure and modeling build-direction-dependent architectonics during additive manufacturing.This strategy enables the development of a compositional gradient from the center to the edge of each melt pool of the Mg_(2)Si–SiC/nitride hybrid composite.Consequently,the coefficient of friction of the hybrid composite exhibits a 309.3%decrease to–1.67 compared to–0.54 for the conventional nonreinforced Mg_(2)Si structure,while the tensile strength exhibits a 171.3%increase to 831.5 MPa compared to 485.3 MPa for the conventional structure.This outstanding mechanical behavior is due to the(1)the complementary and synergistic reinforcement effects of the SiC and nitride compounds,each of which possesses an intrinsically high hardness,and(2)the strong adhesion of these compounds to the Mg_(2)Si matrix despite their small sizes and low concentrations.

Analysis of the Protein Structure and Function of HpaG_(Xoo)

[Objective] The study was to analyze the structure and function of HpaGXoo and the relationship between the two.[Method] Some related bioinformatics analysis software on internet such as NPSA,Swiss-Model,SAPS and InterPro Scan were adopted to analyze the structure and predict its function.[Result] HpaGXoo consists of 139 amino acids,and has many alpha-helical and coiled structure,no signal peptide on N-terminal and no transmembrane structure.It locates in bacterial cytoplasm.[Conclusion] The study will lay ...

Analysis of Emergy Structure,Function and Efficiency of Agro-ecosystem in Hunan Province

[Objective] The aim was to explore function and efficiency of emergy input/ output of Hunan agricultural ecosystem to reveal relationship of human being with natural resources and environment. [Method] Emergy structure, function and efficien- cy of Hunan agricultural ecosystem were analyzed based on input/output data in Hunan Province in 2009 as per emergy theory. [Result] The structure characters of agricultural ecosystem were as follows： Hunan is characterized with traditional agri- culture, depending greatly on both human and animal labor. For industrial accessory emergy, chemical fertilizers make most contribution to the system, and agricultural mechanization is not satisfied. Furthermore, renewable ratio of industrial accessory emergy is lower, and development and potential of green energy is promising. In addition, prices of the products are lower, without consideration of contribution made by natural resources and environment. It also suggested that Hunan agricultural chain is short and added value of products is not high. In general, emergy output of farming and animal husbandry dominates and the prices are lower than those of forestry and fishery. The function of the system was as follows： With lower environ- mental load ratio, the system is overloaded by population and the index of sustain- able development was 5.96, suggesting that the system enjoys vitality and potential, but the economy is undeveloped and the pressure from natural resources and envi- ronment is not high. The emergy output ratio was a little lower than national level in 2009, suggesting Hunan agricultural production is extensive. [Conclusion] The re- search indicated that rapid increase of population should be controlled; surplus labor should be transferred; agricultural structure and products structure should be further adjusted; agricultural technology should be further developed; agdcultural mechaniza- tion and modernization should be improved.

Function and structure of the farmland shelterbelts in northern area of Shanxi Province

From the 1950s to 1960s, large area of Populus simonii shelterbelts system was established in northern area of Shanxi Province. For reconstructing the old shelterbelts, more attentions should be paid to selecting suitable tree species and design of logical shelterbelts structure. In order to provide a profound basis for the efficient establishment of shelterbelts, the study on function and structure of the farmland shelterbelts was conducted in Shuozhou and Datong areas, both are semi-arid areas in Northern Shanxi Province during 1996-2001. The wind-control effects of shelterbelts with different structures (close-spaced, wider-spaced, and widest-spaced) were investigated by portable wind vane and anemometer, wet and dry bulb thermometer, ground thermometer, glass service instrument. The results showed that the wind-control capacity of the shelterbelts during the leafing period should be thought as the criteria index in shelterbelts established. The wider-spaced shelterbelt that was made of 4-6 rows of trees, with a spacing of 2.0 m×3.0 m, had the best wind-control result.

Functional Equilibrium Between Photosynthetic and Above-ground Nonphotosynthetic Structures of Plants: Evidence from a Pruning Experiment with Three Subtropical Tree Species

It is well known that plants have functional equilibrium between their above-ground parts (shoots) and below-ground parts (roots), but whether the above-ground parts of plants have functional equilibrium between their photosynthetic structures (leaves) and non-photosynthetic structures (branches and stem) is unknown. The purpose of this study is to test the hypotheses that: (1) the above-ground parts of plants have functional equilibriums between their photosynthetic structures and non-photosynthetic structures; (2) the maintenance of the equilibriums is guaranteed by the alteration of biomass partitioning to photosynthetic and non-photosynthetic structures. To test these hypotheses, a pruning experiment with four pruning intensities (0%, 20%, 50%, and 70%) were carried out with three subtropical Chinese tree species ( Ficus microcarpa, Ficus virens, Cinnamomum camphora). Pruning treatments were conducted in two successive years. The results were in conformity with the hypothesis, i.e. above-ground parts of trees had functional equilibriums between photosynthetic and non-photosynthetic structures. Pruning decreased instantaneously the mass ratios of photosynthetic structures to non-photosynthetic structures (P/NP) of all three tree species, the reduction in P/NP was strengthened with pruning intensity. However, one year after pruning, the P/NP of all pruned trees increased and were not smaller than those of unpruned trees. In agreement with the expectation, the biomass partitioning of pruned trees was altered, more newly produced above-ground biomass was partitioned to leaf growth and less to branch and stem growth, thus enabled the damaged trees to restore their functional equilibrium between photosynthetic and non-photosynthetic structures. It is clear that the maintenance of functional equilibrium between photosynthetic and non-photosynthetic structures guaranteed by the alteration of biomass partitioning provides plants a good strategy to resist external disturbance and damage.

A study on deep structure using teleseismic receiver function in Western Yunnan

s Western Yunnan is located at the boundary of collision or underthrusting zone of Eurasian plate and is influenced by many times tectonic movements. With very complex geological environment and tectonic background, it is one of the seismically active areas. In the paper, the teleseismic records were selected from 16 national, local and mo-bile stations, including 4 very-wide-band mobile stations of PASSCAL. And nearly 2 000 receiver functions were extracted. Two measuring lines are 650 km and 450 km, respectively and across some major tectonic units in Western Yunnan. It is indicated that Nujiang might be a seam characterized by underthrusting. The western and eastern boundaries of Sichuan-Yunnan rhombus block, i.e., Honghe and Xiaojiang faults, might be an erection seam or collision belt. Panxi tectonic zone still has the characteristics of continental rift valley, that is, the surface is hollow and the upper mantle is upwarping. The tectonic situation in Western Yunnan is of certain regulation with the interlacing distribution of orogenic zone and seam. The crustal thickness decreases gradually from the north to the south and the S wave velocity is globally lower here.

Discussion on Structure Evolution and Function Expansion of Agriculture in China

According to the characteristics of agricultural development during different periods, agricultural development was basically divided into traditional period, planning system period and household contracting pedod to discuss the related laws of agricultural development in China. The agricultural function expansion during different periods was analyzed in terms of agricultural structure evolution, while structural optimization and function expansion of modem agriculture in China were also studied. The results indicated that during the traditional period, agricultural structure emphasized feeding people and grain production while agricultural function reflected the economic function beyond surviving standard. During the planning system period, a unitary structural mode of agriculture was formed in China, which showed that agriculture was dominated by planting industry and planting industry was dominated by grain, while agriculture executed the mixed economic function beyond surviving and liv- ing standard. During the household contracting period, the industrial structure of agriculture in China gradually became diversification and optimi- zation, but as the economic function of industrial standard, agricultural development was still greatly inhibited. The structural evolution of modem agriculture in China must step forward towards collectivization and scale merit, while ecological function and social function of agriculture increas- ingly become important and the function of agricultural production becomes mere and more diverse.

Crystal structure,phase transitions,and thermodynamic properties of magnesium metavanadate(MgV_(2)O_(6))

As a promising anode material for magnesium ion rechargeable batteries,magnesium metavanadate(MgV_(2)O_(6))has attracted considerable research interest in recent years.A MgV_(2)O_(6)sample was synthesized via a facile solid-state reaction by multistep-firing stoichiometric mixtures of MgO and V2O5 powder under an air atmosphere.The solid-state phase transition fromα-MgV_(2)O_(6)toβ-MgV_(2)O_(6)occurred at 841 K and the enthalpy change was 4.37±0.04 kJ/mol.The endothermic effect at 1014 K and the enthalpy change was 26.54±0.26 kJ/mol,which is related to the incongruent melting ofβ-MgV_(2)O_(6).In situ XRD was performed to investigate phase transition of the as-prepared MgV_(2)O_(6)at high temperatures.The cell parameters obtained by Rietveld refinement indicated that it crystallizes in a monoclinic system with the C2/m space group,and the lattice parameters of a=9.280 A°,b=3.501 A°,c=6.731 A°,β=111.76°.The solid-state phase transition fromα-MgV_(2)O_(6)toβ-MgV_(2)O_(6)was further studied by thermal kinetics,indicating that this process is controlled first by a fibril-like mechanism and then by a spherulitic-type mechanism with an increasing heating rate.Additionally,the enthalpy change of MgV_(2)O_(6)at high temperatures was measured utilizing the drop calorimetry,heat capacity was calculated and given as:Cp=208.3+0.03583T-4809000T^(−2)(298-923 K)(J mol^(−1)K^(−1)),the high-temperature heat capacity can be used to calculate Gibbs free energy of MgV_(2)O_(6)at high temperatures.

Evaluation of thermal resistance constitution for packaged AlGaN/GaN high electron mobility transistors by structure function method

The evaluation of thermal resistance constitution for packaged A1GaN/GaN high electron mobility transistor （HEMT） by structure function method is proposed in this paper. The evaluation is based on the transient heating measurement of the A1GaN/GaN HEMT by pulsed electrical temperature sensitive parameter method. The extracted chip-level and package-level thermal resistances of the packaged multi-finger A1GaN/GaN HEMT with 400μm SiC substrate are 22.5 K/W and 7.2 K/W respectively, which provides a non-invasive method to evaluate the chip-level thermal resistance of packaged A1GaN/GaN HEMTs. It is also experimentally proved that the extraction of the chip- level thermal resistance by this proposed method is not influenced by package form of the tested device and temperature boundary condition of measurement stage.

S-wave velocity structure beneath Changbaishan volcano inferred from receiver function

The S wave velocity structure in Changbaishan volcanic region was obtained from teleseismic receiver function modeling. The results show that there exist distinct low velocity layers in crust in volcano area. Beneath WQD station near to the Tianchi caldera the low velocity layer at 8 km depth is 20 km thick with the lowest S-wave velocity about 2.2 km/s At EDO station located 50 km north of Tianchi caldera, no obvious crustal low velocity layer is detected. In the volcanic region, the thickness of crustal low velocity layer is greater and the lowest velocity is more obvious with the distance shorter to the caldera. It indicates the existence of the high temperature material or magma reservoir in crust near the Tianchi caldera. The receiver functions and inversion result from different back azimuths at CBS permanent seismic station show that the thickness of near surface low velocity layer and Moho depth change with directions. The near surface low velocity layer is obviously thicker in south direction. The Moho depth shows slight uplifting in the direction of the caldera located. We con- sider that the special near surface velocity structure is the main cause of relatively lower prominent frequency of volcanic earthquake waveforms recorded by CBS station. The slight uplifting of Moho beneath Tianchi caldera indicates there is a material exchanging channel between upper mantle and magma reservoir in crust.

Electronic structure and optical properties of In-doped SrTiO3 by density function theory

The effect of In doping on the electronic structure and optical properties of SrTiO3 is investigated by the first-principles calculation of plane wave ultra-soft pseudo-potential based on the density function theory （DFT）. The calculated results reveal that due to the hole doping, the Fermi level shifts into valence bands （VBs） for SrTi1-x InxO3 with x = 0.125 and the system exhibits p-type degenerate semiconductor features. It is suggested according to the density of states （DOS） of SrTi0.875In0.125O3 that the band structure of p-type SrTIO3 can be described by a rigid band model. At the same time, the DOS shifts towards high energies and the optical band gap is broadened. The wide band gap, small transition probability and weak absorption due to the low partial density of states （PDOS） of impurity in the Fermi level result in the optical transparency of the film. The optical transmittance of In doped SrTiO3 is higher than 85% in a visible region, and the transmittance improves greatly. And the cut-off wavelength shifts into a blue-light region with the increase of In doping concentration.

Structure and function of the contactin-associated protein family in myelinated axons and their relationship with nerve diseases

The contactin-associated protein （Caspr） family participates in nerve excitation and conduction, and neurotransmitter release in myelinated axons. We analyzed the structures and functions of the Caspr family- CNTNAP1 （Casprl）, CNTNAP2 （Caspr2）, CNTNAP3 （Caspr3）, CNTNAP4 （Caspr4） and CNTNAP5 （Caspr5）, Casprl-5 is not only involved in the formation of myelinated axons, but also participates in maintaining the stability of adjacent connections. Casprl participates in the formation, differentiation, and proliferation of neurons and astrocytes, and in motor control and cognitive function. We also analyzed the relationship between the Caspr family and neurodegenerative diseases, multiple sclerosis, and autoimmune encephalitis. However, the effects of Caspr on disease course and prognosis remain poorly understood. The effects of Caspr on disease diagnosis and treatment need further investigation.

Hydroelastic Analysis of Very Large Floating Structures Using Plate Green Functions

Great attention has been paid to the development of very large floating structures. Owing to their extreme large size and great flexibility, the coupling between the structural deformation and fluid motion is significant. This is a typical problem of hydroelasticity. Efficient and accurate estimation of the hydroelastic response of very large floating structures in waves is very important for design. In this paper, the plate Green function and fluid Green function are combined to analyze the hydroelastic response of very large floating structures. The plate Green function here is a new one proposed by the authors and it satisfies all boundary conditions for free-free rectangular plates on elastic foundations. The results are compared with some experimental data. It is shown that the method proposed in this paper is efficient and accurate. Finally, various factors affecting the hydroelastic response of very large floating structures are also studied.

Electronic structure and flotability of gold-bearing pyrite:A density functional theory study

Various incorporation of Au in pyrite and its effects on the geometrical structure,electronic structure and flotability of pyrite were theoretically investigated and fully discussed by performing density functional theory(DFT).The calculated incorporation energy shows that gold would most likely exist in pyrite via incorporating into interstitial lattice sites in the absence of As impurity.As a result of incorporated Au,the covalence levels of the S—Fe and S—S bonds are changed,and the tonicity of Au—S bonds and antibonding of Au—Fe bonds are found to form in the pyrite,which would change the natural flotability of pyrite.The Au impurity energy levels are introduced into the energy band and result in the transformation of pyrite semiconductivity type.The calculated band-gap value suggests that the incorporated Au significantly decreases pyrite semiconductivity level,which enhances the formation and the adsorption stability of dixanthogen during pyrite flotation.The DOS results reveal that the stability and depression difficulty level of pyrites increases in the following order:Fe_(32)S_(63)As<Fe_(32)S_(64)<Fe_(32)S_(63)As Au<Fe_(32)S_(64)Au.

Systematic analysis of corporate environmental responsibility:elements,structure,function,and principles

Corporate Environmental Responsibility(CER) is the subsystem of Corporate Social Responsibility(CSR),which continues to increase prominence in the global economy.Nowadays,CER becomes more important in corporate sustainable development.Based on Carroll's pyramid mode of CSR,this article explores the systematic feature of CER.From a systematic perspective,it sorts out its elements,structure,function,and principles of CER.And the four levels of economic,legal,ethical,and charitable structure are emphasized.With these considerations interpreted into practice,success will be achieved in potential cost savings,technological innovation,increased public acceptance,and better relations with governments.

Crystal Structure and Density Functional Theory Studies of (p-Methoxyphenyl) Thiosemicarbazide

The title compound [CH3OC6H4NHNHCSNH2] has been characterized by ele- mental analysis, IR, electronic absorption spectra and X-ray single-crystal diffraction. It crystallizes in the monoclinic system, space group C2/c with a = 25.071(5), b = 5.9292(12), c = 14.938(3) ?, β = 118.40(3)o, Mr = 197.26 (C8H11N3OS), V = 1953.3(7) ?3, Z = 8, Dc = 1.342 g/cm3, F(000) = 832, μ = 0.296 mm-1, R = 0.0647 and wR = 0.1433. In the crystal lattice, there exist some intermolecular hydrogen bonds, π-π stacking interactions and C–H…π supramolecular interactions to stabilize the crystal structure. The density functional theory (DFT) calculations at the B3LYP/6-31G* level, charge distributions and thermodynamic properties at different temperature have been performed, showing the sulfur and nitrogen atoms have bigger negative charges because they are the potential sites reacting with the metallic ions.

Characteristics of soil microbial community functional and structure diversity with coverage of Solidago Canadensis L

The relationship between Solidago canadensis L. invasion and soil microbial community diversity including functional and structure diversities was studied across the invasive gradients varying from 0 to 40%, 80%, and 100% coverage of Solidago canadensis L. using sole carbon source utilization profiles analyses, principle component analysis （PCA） and phospholipid fatty acids （PLFA） profiles analyses. The results show the characteristics of soil microbial community functional and structure diversity in invaded soils strongly changed by Solidago canadensis L. invasion. Solidago canadensis L. invasion tended to result in higher substrate richness, and functional diversity. As compared to the native and ecotones, average utilization of specific substrate guilds of soil microbe was the highest in Solidago canadensis L. monoculture. Soil microbial functional diversity in Solidago canadensis L. monoculture was distinctly separated from the native area and the ecotones. Aerobic bacteria, fungi and actinomycetes population significantly increased but anaerobic bacteria decreased in the soil with Solidago canadensis L. monoculture. The ratio of cyl9：0 to 18：1 co7 gradually declined but mono/sat and fung/bact PLFAs increased when Solidago canadensis L. became more dominant. The microbial community composition clearly separated the native soil from the invaded soils by PCA analysis, especially 18： lco7c, 16： lco7t, 16： lco5c and 18：2co6, 9 were present in higher concentrations for exotic soil. In conclusion, Solidago canadensis L. invasion could create better soil conditions by improving soil microbial community structure and functional diversity, which in turn was more conducive to the growth ofSolidago canadensis L.