The pathologic changes in the muscle biopsy specimens of 26 patients with venous insufficiency were studied A total of 19 biopsied specimens of the gastrocnemius exhibited pathologic change, 9 patients had selective a...The pathologic changes in the muscle biopsy specimens of 26 patients with venous insufficiency were studied A total of 19 biopsied specimens of the gastrocnemius exhibited pathologic change, 9 patients had selective atrophy of type 2 fibre, 4 patients had denervative change,and 6 patients had evidence of myopathic change, but specimens removed from adductor longus muscle of patients as the control group revealed no significant change. The results suggest that chronic venous insufficiency results in muscle pathologic changes. The combined effect of elevated venous capacitance secondary to venous insufficiency and poor muscle contraction contributes to venous hypertention.展开更多
文摘The pathologic changes in the muscle biopsy specimens of 26 patients with venous insufficiency were studied A total of 19 biopsied specimens of the gastrocnemius exhibited pathologic change, 9 patients had selective atrophy of type 2 fibre, 4 patients had denervative change,and 6 patients had evidence of myopathic change, but specimens removed from adductor longus muscle of patients as the control group revealed no significant change. The results suggest that chronic venous insufficiency results in muscle pathologic changes. The combined effect of elevated venous capacitance secondary to venous insufficiency and poor muscle contraction contributes to venous hypertention.
