Orlic et al treated mice (splenectomized two weeks ago) with granulocyte colony stimulating factor (G-CSF) and stem cell factor (SCF) for five days before acute myocardium infarction (AMI) and three days after...Orlic et al treated mice (splenectomized two weeks ago) with granulocyte colony stimulating factor (G-CSF) and stem cell factor (SCF) for five days before acute myocardium infarction (AMI) and three days after AMI. They found that those treatments could repair infarcted hearts, improve heart performance and decrease mortality. However, from the clinical standpoint, the work of Orlic and his co-workers has an obvious limitation.展开更多
文摘Orlic et al treated mice (splenectomized two weeks ago) with granulocyte colony stimulating factor (G-CSF) and stem cell factor (SCF) for five days before acute myocardium infarction (AMI) and three days after AMI. They found that those treatments could repair infarcted hearts, improve heart performance and decrease mortality. However, from the clinical standpoint, the work of Orlic and his co-workers has an obvious limitation.