Fifty-six patients with chest pain underwent selective coronaryangiography,radionuclide ventriculography (RNV) and frequency domaincardiography (FCG) to evaluate left ventricular function in coronary artery dis-ease (...Fifty-six patients with chest pain underwent selective coronaryangiography,radionuclide ventriculography (RNV) and frequency domaincardiography (FCG) to evaluate left ventricular function in coronary artery dis-ease (CAD).The sensitivity,specificity and accuracy of FCG were 87.5%,77.8%and 82.9%,respectively,which were slightly less than those of RNV (92.5%,88.9% and 90.8%,respectively).The changes of FCG scores were negatively corre-lated with changes of LVEF (r=-0.586,P【0.01),and TS (r=-0.679,P【0.01).These results indicate that FCG may be useful for the evaluation of leftventricular function in patients with CAD.展开更多
Catheter based ventriculography has evolved over the last century and in many instances has been replaced by use of cardiac ultrasound.Despite the shift,ventricular function remains an important part of assessing myoc...Catheter based ventriculography has evolved over the last century and in many instances has been replaced by use of cardiac ultrasound.Despite the shift,ventricular function remains an important part of assessing myocardial damage and prognosis.There is no doubt that cardiac ultrasound can evaluate LV size,myocardial wall motion and wall thickening,and is non-invasive,readily available,relatively inexpensive and portable.Poor acoustic windows are the major limitation of cardiac ultrasound as are foreshortened imaging planes.In contrast,catheter based left ventriculography,can evaluate similar attributes of LV function but limitations are that it is invasive requiring arterial access,involves radiation exposure,and the use of iodinated radio-opaque contrast which may result in renal dysfunction.The Society of Cardiovascular angiography and Intervention(SCAI)recommendations for catheter based left ventriculography are consensus opinions which need rigorous prospective evaluation.Probably the most important SCAI recommendation is that local criteria should be developed to decrease variation in performance among operators within individual catheterization laboratories.No data are available to determine which patient gets catheter based left ventriculography or echo assessment of ventricular function.Decision making regarding the use of catheter based or ultrasound based angiography is quite complex because of limitation and interaction of the various determinants,e.g.creatinine,diabetes,gender,contrast volume and fl uoro time.展开更多
A 78-year-old woman with a background of type 2 diabetes mellitus,hyperlipidaemia and hypertension experienced sudden onset severe chest pain while in the emergency department,after a stressful emotional event.The pai...A 78-year-old woman with a background of type 2 diabetes mellitus,hyperlipidaemia and hypertension experienced sudden onset severe chest pain while in the emergency department,after a stressful emotional event.The pain lasted for 20-30 min and the patient developed widespread T-wave inversion on 12-lead ECG.展开更多
Tako-tsubo cardiomyopathy(TC) is a recently described acute cardiac syndrome, which the latest cardiomyopathy classification of the European Society of Cardiology describes as an unclassified cardiomyopathy. TC mimi...Tako-tsubo cardiomyopathy(TC) is a recently described acute cardiac syndrome, which the latest cardiomyopathy classification of the European Society of Cardiology describes as an unclassified cardiomyopathy. TC mimics acute myocardial infarction(AMI) and is characterised by ischaemic chest symptoms, an elevated electrocardiogram ST-segment, and moderately increased levels of cardiac disease markers. However, patients with TC have no coronary angiogram-detectable or non-obstructive coronary arterial disease(CAD), and left ventriculography documents transient left apical and middle ventricular wall dysfunction. In this review, we describe TC and evaluate epidemiological, clinical and instrumental features, pathophysiological mechanisms, therapy and prognosis of this syndrome,with a view to raising awareness of the disease.展开更多
A 90-year-old Chinese man was transferred to the Emergency Department of the Affiliated Shantou Hospital of Sun Yat-sen University for treatment of an acute myocardial infarction. He suffered chest pain with three day...A 90-year-old Chinese man was transferred to the Emergency Department of the Affiliated Shantou Hospital of Sun Yat-sen University for treatment of an acute myocardial infarction. He suffered chest pain with three days of cough, dyspnea and fever. A diagnosis of Takotsubo cardiomyopathy was made in normal coronary arteries from urgent coronary angiography and characteristic apical dyskinesis and basal hyper contractility in left ventriculography. The patient died from severe multi-organ failure on the second day of hospitalization.展开更多
文摘Fifty-six patients with chest pain underwent selective coronaryangiography,radionuclide ventriculography (RNV) and frequency domaincardiography (FCG) to evaluate left ventricular function in coronary artery dis-ease (CAD).The sensitivity,specificity and accuracy of FCG were 87.5%,77.8%and 82.9%,respectively,which were slightly less than those of RNV (92.5%,88.9% and 90.8%,respectively).The changes of FCG scores were negatively corre-lated with changes of LVEF (r=-0.586,P【0.01),and TS (r=-0.679,P【0.01).These results indicate that FCG may be useful for the evaluation of leftventricular function in patients with CAD.
文摘Catheter based ventriculography has evolved over the last century and in many instances has been replaced by use of cardiac ultrasound.Despite the shift,ventricular function remains an important part of assessing myocardial damage and prognosis.There is no doubt that cardiac ultrasound can evaluate LV size,myocardial wall motion and wall thickening,and is non-invasive,readily available,relatively inexpensive and portable.Poor acoustic windows are the major limitation of cardiac ultrasound as are foreshortened imaging planes.In contrast,catheter based left ventriculography,can evaluate similar attributes of LV function but limitations are that it is invasive requiring arterial access,involves radiation exposure,and the use of iodinated radio-opaque contrast which may result in renal dysfunction.The Society of Cardiovascular angiography and Intervention(SCAI)recommendations for catheter based left ventriculography are consensus opinions which need rigorous prospective evaluation.Probably the most important SCAI recommendation is that local criteria should be developed to decrease variation in performance among operators within individual catheterization laboratories.No data are available to determine which patient gets catheter based left ventriculography or echo assessment of ventricular function.Decision making regarding the use of catheter based or ultrasound based angiography is quite complex because of limitation and interaction of the various determinants,e.g.creatinine,diabetes,gender,contrast volume and fl uoro time.
文摘A 78-year-old woman with a background of type 2 diabetes mellitus,hyperlipidaemia and hypertension experienced sudden onset severe chest pain while in the emergency department,after a stressful emotional event.The pain lasted for 20-30 min and the patient developed widespread T-wave inversion on 12-lead ECG.
文摘Tako-tsubo cardiomyopathy(TC) is a recently described acute cardiac syndrome, which the latest cardiomyopathy classification of the European Society of Cardiology describes as an unclassified cardiomyopathy. TC mimics acute myocardial infarction(AMI) and is characterised by ischaemic chest symptoms, an elevated electrocardiogram ST-segment, and moderately increased levels of cardiac disease markers. However, patients with TC have no coronary angiogram-detectable or non-obstructive coronary arterial disease(CAD), and left ventriculography documents transient left apical and middle ventricular wall dysfunction. In this review, we describe TC and evaluate epidemiological, clinical and instrumental features, pathophysiological mechanisms, therapy and prognosis of this syndrome,with a view to raising awareness of the disease.
文摘A 90-year-old Chinese man was transferred to the Emergency Department of the Affiliated Shantou Hospital of Sun Yat-sen University for treatment of an acute myocardial infarction. He suffered chest pain with three days of cough, dyspnea and fever. A diagnosis of Takotsubo cardiomyopathy was made in normal coronary arteries from urgent coronary angiography and characteristic apical dyskinesis and basal hyper contractility in left ventriculography. The patient died from severe multi-organ failure on the second day of hospitalization.