Purpose: To explore the significance of dual-source computed tomography (DECT) virtual monoenergetic reconstructions technology in improving image quality for portal vein system of pancreatic cancer patients. Material...Purpose: To explore the significance of dual-source computed tomography (DECT) virtual monoenergetic reconstructions technology in improving image quality for portal vein system of pancreatic cancer patients. Materials and methods: 47 patients with clinically suspected pancreatic cancer (all confirmed by pathology) were collected. Routine plain scan was performed with Siemens Force dual-source dual-energy CT followed by 3 scans respectively carried out in arterial phase, portal phase and delayed phase. Traditional virtual monoenergetic reconstructions (Mono_E) and new generation of virtual monoenergetic reconstructions (Mono+) were respectively performed on portal vein images to obtain virtual single energy images including Mono_ E70 keV, Mono_E 55 keV and Mono+ 70 keV and Mono+ 55 keV. The signal-to-noise ratio (SNR) and noise of portal vein, normal pancreatic tissues and pancreatic lesions of 100 kV, Mono_E and Mono+ images were compared. In addition, the contrast noise ratio of portal vein and lesions as well as pancreatic tissues and lesions (CNR PV, CNRtumor) were also compared. At the same time, two imaging physicians with rich clinical experiences read the films and scored the images of each group by using the 5-point scoring method. Results: Mono+ 55 keV images including SNRpv, SNRpanc, SNRtumor, Noise, CNRpv, CNRtumor were statistically different from 100 KV images and Mono_E images (P < 0.05). As for the subjective score, Mono+ 55 keV image score also had the highest score, which had statistical significance (P < 0.05). The results showed that Mono+ 55 keV images had the best quality. Conclusion: The new generation of virtual Mono+ post-treatment can reduce image noise. Low energy Mono+ images can improve the contrast between pancreatic cancer lesions and portal of pancreatic cancer patients.展开更多
目的 比较能谱CT金属伪影去除算法及虚拟单能图像重建与传统迭代重建在减少脊柱金属植入物伪影的差异。方法 56例脊柱矫形术接受金属植入物行标准能谱CT检查,包括常规迭代重建、金属伪影去除算法和虚拟单能图像重建。测量衰减系数(HU)...目的 比较能谱CT金属伪影去除算法及虚拟单能图像重建与传统迭代重建在减少脊柱金属植入物伪影的差异。方法 56例脊柱矫形术接受金属植入物行标准能谱CT检查,包括常规迭代重建、金属伪影去除算法和虚拟单能图像重建。测量衰减系数(HU)和噪声(SD),以计算椎旁肌和椎管的信噪比。两名放射科医师独立评价图像质量和伪影减少程度。结果 与常规迭代重建相比,金属伪影去除算法和高keV虚拟单能图像显著降低低密度伪影及高密度伪影。与常规迭代重建相比,金属伪影去除算法和高keV虚拟单能图像椎旁肌(34.6±17.0HU vs. 26.1±13.5HU及34.6±17.0HU vs. 27.0±14.2)和椎管(102.5±60.1HU vs. 72.1±39.3HU及102.5±60.1HU vs. 60.1±38.0HU, P 均<0.05)的噪声伪影减少。观察者间评价主观图像质量的一致性良好,ICC=0.74。在主观图像质量评价中,金属伪影去除算法和高keV虚拟单能图像上表现出伪影减少分别为44/56例(78.6%)、48/56例(85.7%)。结论 能谱CT金属伪影去除算法和高keV虚拟单能图像重建上客观及主观伪像均减少,金属伪影去除算法联合虚拟单能图像的组合可能有希望进一步减少伪影。展开更多
目的:评估炎症性肠病(inflammatory bowel disease,IBD)患者腹部双能量CT(dual-energy CT,DECT)扫描不同能级噪声优化的虚拟单能量图像(noise-optimized virtual monoenergetic imaging,VMI+)的主观和客观图像质量,得出最佳重建参数,提...目的:评估炎症性肠病(inflammatory bowel disease,IBD)患者腹部双能量CT(dual-energy CT,DECT)扫描不同能级噪声优化的虚拟单能量图像(noise-optimized virtual monoenergetic imaging,VMI+)的主观和客观图像质量,得出最佳重建参数,提高IBD诊断准确率。方法:选取2016年4月到2017年6月确诊为IBD的32名患者腹部DECT扫描图像进行线性融合(M_0.6)、VMI+、传统虚拟单能量图像(virtual monoenergetic imaging,VMI)重建,虚拟能级为40~100 ke V,间隔为10 ke V。以病变肠段部位的图像信噪比(signal-to-noise ratio,SNR)和对比噪声比(contrast-to-noise ratio,CNR)作为客观图像质量评价标准,主观图像质量评价由3名放射科医生对总体图像质量、锐利度、病变轮廓、噪声4个方面进行双盲评估。结果:客观图像质量评价最佳重建参数为40 ke V VMI+(SNR 8.28±2.34;CNR 5.10±2.10),优于线性融合图像(SNR 5.82±1.44;CNR 1.53±0.86)和传统VMI(P<0.01)。主观图像质量评价中,50 ke V VMI+总体图像质量(均值4.80)高于其他图像(P<0.01),40和50 ke V VMI+锐利度最高(均值分别为4.14和4.25,P=0.415),40 ke V VMI+显示病变轮廓能力评分高于其他图像(均值4.52,P<0.01)。100 ke V VMI+和100 ke V VMI噪声最低(均值分别为4.58和4.40,P≥0.11)。结论:相比于线性融合和传统VMI重建,低能级VMI+可显著提高IBD病变部位的腹部DECT扫描图像的主观和客观图像质量。展开更多
目的研究双源双能量噪声优化的虚拟单能谱成像技术(VMI+)对下肢CT静脉成像(CTV)和肺动脉成像(CTPA)联合扫描中下肢静脉图像质量的影响,且以超声为参考标准评估CTV对下肢静脉血栓的诊断性能。方法回顾性分析53例临床怀疑肺栓塞(PE)进行CT...目的研究双源双能量噪声优化的虚拟单能谱成像技术(VMI+)对下肢CT静脉成像(CTV)和肺动脉成像(CTPA)联合扫描中下肢静脉图像质量的影响,且以超声为参考标准评估CTV对下肢静脉血栓的诊断性能。方法回顾性分析53例临床怀疑肺栓塞(PE)进行CTPA-CTV联合检查的患者的图像,利用双源双能量单能谱成像技术分别重建下肢静脉在40、50、60keV的三组虚拟单能谱图像(VMI+40 ke V、VMI+50keV、VMI+60keV),以及线性融合图像(融合系数0.5)。记录线性融合图像和三组单能谱图像的衰减值(CT值)、对比噪声比(CNR)及信号噪声比(SNR),以三分制对图像进行主观评分。以超声(US)对血栓的诊断结果为参考标准,计算下肢CTV诊断下肢深静脉血栓(DVT)的特异性、敏感性、阳性预测值及阴性预测值;使用Kappa检验分析两种方法对DVT显示的一致性。结果单能谱图像和线性融合图像的CT值及CNR值存在统计学差异(H=116.455,P=0.000及H=22.362,P=0.000),其中VMI+40 keV的CT值(204.63±56.40HU)及CNR值(7.72±4.72)最高。四组图像的主观评分存在统计学差异(H=14.097,P=0.003),其中VMI+40 keV的评分(2.62±0.49)最高。在37位同时进行CTV及US检查的患者中,CTV对DVT的诊断敏感性、特异性、阳性预测值及阴性预测值分别为84.2%(16/19)、77.8%(14/18)、80.0%(16/20)及82.4%(14/17)。结论双源双能量单能谱成像技术显著提高肺动脉及下肢静脉联合成像中下肢静脉的图像质量,且具有较高的血栓诊断性能。展开更多
文摘Purpose: To explore the significance of dual-source computed tomography (DECT) virtual monoenergetic reconstructions technology in improving image quality for portal vein system of pancreatic cancer patients. Materials and methods: 47 patients with clinically suspected pancreatic cancer (all confirmed by pathology) were collected. Routine plain scan was performed with Siemens Force dual-source dual-energy CT followed by 3 scans respectively carried out in arterial phase, portal phase and delayed phase. Traditional virtual monoenergetic reconstructions (Mono_E) and new generation of virtual monoenergetic reconstructions (Mono+) were respectively performed on portal vein images to obtain virtual single energy images including Mono_ E70 keV, Mono_E 55 keV and Mono+ 70 keV and Mono+ 55 keV. The signal-to-noise ratio (SNR) and noise of portal vein, normal pancreatic tissues and pancreatic lesions of 100 kV, Mono_E and Mono+ images were compared. In addition, the contrast noise ratio of portal vein and lesions as well as pancreatic tissues and lesions (CNR PV, CNRtumor) were also compared. At the same time, two imaging physicians with rich clinical experiences read the films and scored the images of each group by using the 5-point scoring method. Results: Mono+ 55 keV images including SNRpv, SNRpanc, SNRtumor, Noise, CNRpv, CNRtumor were statistically different from 100 KV images and Mono_E images (P < 0.05). As for the subjective score, Mono+ 55 keV image score also had the highest score, which had statistical significance (P < 0.05). The results showed that Mono+ 55 keV images had the best quality. Conclusion: The new generation of virtual Mono+ post-treatment can reduce image noise. Low energy Mono+ images can improve the contrast between pancreatic cancer lesions and portal of pancreatic cancer patients.
文摘目的 比较能谱CT金属伪影去除算法及虚拟单能图像重建与传统迭代重建在减少脊柱金属植入物伪影的差异。方法 56例脊柱矫形术接受金属植入物行标准能谱CT检查,包括常规迭代重建、金属伪影去除算法和虚拟单能图像重建。测量衰减系数(HU)和噪声(SD),以计算椎旁肌和椎管的信噪比。两名放射科医师独立评价图像质量和伪影减少程度。结果 与常规迭代重建相比,金属伪影去除算法和高keV虚拟单能图像显著降低低密度伪影及高密度伪影。与常规迭代重建相比,金属伪影去除算法和高keV虚拟单能图像椎旁肌(34.6±17.0HU vs. 26.1±13.5HU及34.6±17.0HU vs. 27.0±14.2)和椎管(102.5±60.1HU vs. 72.1±39.3HU及102.5±60.1HU vs. 60.1±38.0HU, P 均<0.05)的噪声伪影减少。观察者间评价主观图像质量的一致性良好,ICC=0.74。在主观图像质量评价中,金属伪影去除算法和高keV虚拟单能图像上表现出伪影减少分别为44/56例(78.6%)、48/56例(85.7%)。结论 能谱CT金属伪影去除算法和高keV虚拟单能图像重建上客观及主观伪像均减少,金属伪影去除算法联合虚拟单能图像的组合可能有希望进一步减少伪影。
文摘目的:评估炎症性肠病(inflammatory bowel disease,IBD)患者腹部双能量CT(dual-energy CT,DECT)扫描不同能级噪声优化的虚拟单能量图像(noise-optimized virtual monoenergetic imaging,VMI+)的主观和客观图像质量,得出最佳重建参数,提高IBD诊断准确率。方法:选取2016年4月到2017年6月确诊为IBD的32名患者腹部DECT扫描图像进行线性融合(M_0.6)、VMI+、传统虚拟单能量图像(virtual monoenergetic imaging,VMI)重建,虚拟能级为40~100 ke V,间隔为10 ke V。以病变肠段部位的图像信噪比(signal-to-noise ratio,SNR)和对比噪声比(contrast-to-noise ratio,CNR)作为客观图像质量评价标准,主观图像质量评价由3名放射科医生对总体图像质量、锐利度、病变轮廓、噪声4个方面进行双盲评估。结果:客观图像质量评价最佳重建参数为40 ke V VMI+(SNR 8.28±2.34;CNR 5.10±2.10),优于线性融合图像(SNR 5.82±1.44;CNR 1.53±0.86)和传统VMI(P<0.01)。主观图像质量评价中,50 ke V VMI+总体图像质量(均值4.80)高于其他图像(P<0.01),40和50 ke V VMI+锐利度最高(均值分别为4.14和4.25,P=0.415),40 ke V VMI+显示病变轮廓能力评分高于其他图像(均值4.52,P<0.01)。100 ke V VMI+和100 ke V VMI噪声最低(均值分别为4.58和4.40,P≥0.11)。结论:相比于线性融合和传统VMI重建,低能级VMI+可显著提高IBD病变部位的腹部DECT扫描图像的主观和客观图像质量。
文摘目的研究双源双能量噪声优化的虚拟单能谱成像技术(VMI+)对下肢CT静脉成像(CTV)和肺动脉成像(CTPA)联合扫描中下肢静脉图像质量的影响,且以超声为参考标准评估CTV对下肢静脉血栓的诊断性能。方法回顾性分析53例临床怀疑肺栓塞(PE)进行CTPA-CTV联合检查的患者的图像,利用双源双能量单能谱成像技术分别重建下肢静脉在40、50、60keV的三组虚拟单能谱图像(VMI+40 ke V、VMI+50keV、VMI+60keV),以及线性融合图像(融合系数0.5)。记录线性融合图像和三组单能谱图像的衰减值(CT值)、对比噪声比(CNR)及信号噪声比(SNR),以三分制对图像进行主观评分。以超声(US)对血栓的诊断结果为参考标准,计算下肢CTV诊断下肢深静脉血栓(DVT)的特异性、敏感性、阳性预测值及阴性预测值;使用Kappa检验分析两种方法对DVT显示的一致性。结果单能谱图像和线性融合图像的CT值及CNR值存在统计学差异(H=116.455,P=0.000及H=22.362,P=0.000),其中VMI+40 keV的CT值(204.63±56.40HU)及CNR值(7.72±4.72)最高。四组图像的主观评分存在统计学差异(H=14.097,P=0.003),其中VMI+40 keV的评分(2.62±0.49)最高。在37位同时进行CTV及US检查的患者中,CTV对DVT的诊断敏感性、特异性、阳性预测值及阴性预测值分别为84.2%(16/19)、77.8%(14/18)、80.0%(16/20)及82.4%(14/17)。结论双源双能量单能谱成像技术显著提高肺动脉及下肢静脉联合成像中下肢静脉的图像质量,且具有较高的血栓诊断性能。