Objective The aim of our study was to analyze the characters of breast pure mucinous carcinomas on highfrequency ultrasonography with virtual touch tissue quantification (VTQ).
Objective： The aim of our study was to make the qualitative and quantitative analysis to breast lesions using acoustic radiation force impulses （ARFI）, and assess the diagnostic value of ARFI for differentiation be...Objective： The aim of our study was to make the qualitative and quantitative analysis to breast lesions using acoustic radiation force impulses （ARFI）, and assess the diagnostic value of ARFI for differentiation between benign and malignant solid breast masses, meanwhile evaluate the influences of ARFI with breast imaging reporting and data system （BI-RADS） of suspicious masses. Methods： Seventy-five women with 86 breast lesions underwent conventional breast ultra- sound examination. Then B-mode BI-RADS features and assessments were recorded and standard breast US supplemented by ARFI elastographic examination were repeated. The data were recorded and analyzed as following： area ratio of breast lesion, the shear-wave velocity, the ratio of the shear-wave velocity between lesions and surrounding normal tissues, and according to the elastographic data reconsidered the BI-RADS category, all the results have been correlated with pathological results and make statistical evaluations of ARFI for differentiation between benign and malignant solid breast masses. Meantime our study has correlated the adjusted BI-RADS category of suspicious breast lesions with the pathological results and made assessment. Results： Thirty-eight patients were malignant breast carcinoma （31 invasive ductal carcinoma, 5 intraductal carcinoma in situ, 2 medullary carcinoma, 2 invasive Iobular carcinoma）, 48 patients were benign breast lesions （23 fibroadenoma, 12 benign nodular hyperplasia, 5 phyllodes tumor, 6 adenosis, 2 intraductal papilloma）. Underwent conventional breast ultrasound exam, 42 cases were BI-RADS category 3, 23 cases were BI-RADS category 4. When adding elastographic data, 46 cases were BI-RADS category 3 and 20 cases were BI-RADS category 4. Compared with pathological results showed for both the specificity of BIRADS features and the area under ROC curve has risen. Virtual touch tissue imaging （VTI） and virtual touch tissue quantification （VTQ） data showed the area ratio （AR） between elastographic lesions area and B-mode lesions area, SWV （maximal shear-wave velocity of lesions）, R-SWV （shear-wave velocity ratio between lesions and surrounding normal tissues） in benign breast lesions were lower than those in malignant lesions which has statistical significance and the cut-off point were 1.1,4.65 m/s, 5.18 respectively. Conclusion： The ARFI elastography can provide the reliable qualitative and quantitative analysis about hardness of breast lesions, supply the new BI-RADS category features to suspicious breast masses and serve as an effective diagnostic tool for differentiation between benign and malignant solid masses.展开更多
目的:探讨自动乳腺容积成像(automated breast volume scanning,ABVS)和声脉冲辐射力成像(acoustic radiation force impulse,ARFI)两种超声技术联合对常规超声诊断为可疑乳腺肿块的良恶性鉴别诊断能力。方法:对118例乳腺肿块常规超声...目的:探讨自动乳腺容积成像(automated breast volume scanning,ABVS)和声脉冲辐射力成像(acoustic radiation force impulse,ARFI)两种超声技术联合对常规超声诊断为可疑乳腺肿块的良恶性鉴别诊断能力。方法:对118例乳腺肿块常规超声评估分类为乳腺影像报告和数据系统(Breast Imaging Reporting And Data System,BI-RADS)4类及以上的患者,应用ABVS分析肿块有无冠状面图像特征(汇聚征与微钙化),应用ARFI检测声触诊组织成像(virtual touch tissue imaging,VTI)中肿块在弹性图与二维图的面积比和声触诊组织量化成像(virtual touch tissue imaging quantification,VTIQ)中肿块剪切波速度的平均值(V_(mean)),对乳腺肿块良恶性的图像按照冠状面有无汇聚征、有无微钙化分类,有任意一种即记为阳性;VTI肿块面积比值大于1.65记为阳性;V_(mean)大于4.14 m/s为阳性。计算并比较ABVS、ARFI单独以及两者联合诊断BI-RADS 4类乳腺肿块的灵敏度、特异度、准确度、阳性预测值、阴性预测值。结果:乳腺肿块在ARFI的检查中,恶性肿块的VTI面积比(1.76±0.61)高于良性肿块VTI面积比(1.14±0.48),恶性肿块的V_(mean)[(6.38±1.76)m/s]高于良性肿块[(4.17±1.43)m/s],差异均有统计学意义(P<0.01)。在BI-RADS 4类乳腺肿块中,ABVS检查中汇聚征或微钙化对恶性乳腺肿块检出的灵敏度、特异度、准确度、阳性预测值及阴性预测值分别为92%、78.3%、84.5%、78.0%及92.2%;VTI诊断乳腺恶性肿块的灵敏度、特异度、准确度、阳性预测值及阴性预测值分别为70.0%、81.7%、76.4%、76.1%及76.6%;VTIQ诊断恶性乳腺肿块的灵敏度、特异度、准确度、阳性预测值、阴性预测值分别为96.0%、58.3%、75.5%、65.8%及94.6%。ABVS与ARFI两者联合诊断的灵敏度、特异度、准确度、阳性预测值、阴性预测值分别为100.0%、50.0%、72.7%、62.5%及100.0%。结论:ABVS与ARFI可补充常规二维超声无法获得的乳腺肿块信息,丰富肿块诊断的依据,扩展疾病鉴别诊断的思路,两者结合可达到优势互补的效果,有助于提高诊断的准确度。展开更多
文摘Objective The aim of our study was to analyze the characters of breast pure mucinous carcinomas on highfrequency ultrasonography with virtual touch tissue quantification (VTQ).
文摘Objective： The aim of our study was to make the qualitative and quantitative analysis to breast lesions using acoustic radiation force impulses （ARFI）, and assess the diagnostic value of ARFI for differentiation between benign and malignant solid breast masses, meanwhile evaluate the influences of ARFI with breast imaging reporting and data system （BI-RADS） of suspicious masses. Methods： Seventy-five women with 86 breast lesions underwent conventional breast ultra- sound examination. Then B-mode BI-RADS features and assessments were recorded and standard breast US supplemented by ARFI elastographic examination were repeated. The data were recorded and analyzed as following： area ratio of breast lesion, the shear-wave velocity, the ratio of the shear-wave velocity between lesions and surrounding normal tissues, and according to the elastographic data reconsidered the BI-RADS category, all the results have been correlated with pathological results and make statistical evaluations of ARFI for differentiation between benign and malignant solid breast masses. Meantime our study has correlated the adjusted BI-RADS category of suspicious breast lesions with the pathological results and made assessment. Results： Thirty-eight patients were malignant breast carcinoma （31 invasive ductal carcinoma, 5 intraductal carcinoma in situ, 2 medullary carcinoma, 2 invasive Iobular carcinoma）, 48 patients were benign breast lesions （23 fibroadenoma, 12 benign nodular hyperplasia, 5 phyllodes tumor, 6 adenosis, 2 intraductal papilloma）. Underwent conventional breast ultrasound exam, 42 cases were BI-RADS category 3, 23 cases were BI-RADS category 4. When adding elastographic data, 46 cases were BI-RADS category 3 and 20 cases were BI-RADS category 4. Compared with pathological results showed for both the specificity of BIRADS features and the area under ROC curve has risen. Virtual touch tissue imaging （VTI） and virtual touch tissue quantification （VTQ） data showed the area ratio （AR） between elastographic lesions area and B-mode lesions area, SWV （maximal shear-wave velocity of lesions）, R-SWV （shear-wave velocity ratio between lesions and surrounding normal tissues） in benign breast lesions were lower than those in malignant lesions which has statistical significance and the cut-off point were 1.1,4.65 m/s, 5.18 respectively. Conclusion： The ARFI elastography can provide the reliable qualitative and quantitative analysis about hardness of breast lesions, supply the new BI-RADS category features to suspicious breast masses and serve as an effective diagnostic tool for differentiation between benign and malignant solid masses.
