Numerical Experiment of Combined Infrared and Ultraviolet Radiation Remote Sensing to Determine the Profile and Total Content of Atmospheric Ozone

A new remote sensing method is described to determine the vertical distribution and total content of atmospheric ozone. The method combines surface infrared, satellite infrared and ultraviolet channels. The width of the infrared channels is 0.01 cm-1, less than Lorentz half-width at the earth's surface, rather than the present width, because these channels can obtain information about variations in the ozone profile below the profile main-peak. The numerical experiments show that the method has a satisfactory precision in determining total ozone content, just about I percent error, and vertical distribution from the earth to 65 km space. In addition, some semi-analysis functions lor calculating backscattered ultraviolet and a relaxation equation are described in this paper.

Yue Oprea Town:Combination of Cultural Experience, Travel and RfecTeation

I he project in Shengzhou broke ground in 201 7 summer and the first phase opened on December 30, 2018. Located in Shijia ao-a village in Shengzhou which is the birthplace of Yue Opera, the Yue Opera-themed tourist city is aimed to show traditional opera and skills and unique philosophy in exploring tourists' demand and building cultural and recreational experiences and interaction.I he space for performing and content design of the project is closely related to elements of Yue Opera. The opera building is the major building of the project. Famous opera troupes from many places were invited to the opening show, presenting classic opera highlights.

Spatiotemporal evolution rule of rocks fracture surrounding gob-side roadway with model experiments

A series of plane-strain physical model experiments are carried out to study the spatiotemporal evolution rule of rocks fracture surrounding gob-side roadway, which is subjected to the pressure induced by the mining process. The digital photogrammetry technology and large deformation analysis method are applied to measure the deformation and fracture of surrounding rocks. The experimental results indicate that the deformation and fracture of coal pillars are the cause to the instability and failure of the surrounding rocks. The spatiotemporal evolution rule of the rock deformation and fracture surrounding gob-side roadway is obtained. The coal pillar and the roof near coal pillar should be strengthened in support design. The engineering application results also can provide a useful guide that the combined support with wire meshes, beam, anchor bolt and cable is an effective method.

A single center experience of combined liver and kidney transplantation

Objective To summarize the experience of treating the end stage of liver disease complicated with renal failure using combined liver - kidney transplantation. Methods The clinical data of 28 cases receiving combined liver - kidney transplantation were retrospectively ana-

田旭东主任医师论治慢性萎缩性胃炎伴肠化临证经验

慢性萎缩性胃炎为消化科常见疾病,与感染、饮食及情绪等密切相关,临床症状常不显著。受多种因素影响,慢性萎缩性胃炎伴肠化有癌变风险,及时发现并及早干预成为预防癌变的关键一步。田旭东主任医师从事消化道疾病诊疗工作已有30余年,对慢性萎缩性胃炎伴肠化具有独特的诊疗思路,提出“病有三分,巧分轻中重,病有三辨,巧辨性位因,选方要专,用药应简,既病防变”,并提出中西药联合使用,并能在短期内取得可观效果。

ACI-SPOC教学模式在中药学专业仪器分析实验的应用

文章探索了以超星学习通平台为载体,以自主、协作、互动学习(ACI)能力培养为导向,建立ACI-小规模限制性在线课程(SPOC)教学模式,用于仪器分析实验教学。通过教学质量评价和问卷调查,从学生学习效果、学习兴趣和能力培养等方面对教改班和传统班进行了对比。结果表明,教改班的教学效果优于传统班,教改班的考试平均分比传统班高26分。ACISPOC教学模式不仅解决了学生学习效果差的问题,还能帮助学生充分调动学习兴趣、激发实验热情、提升科研素养,为培养创新型人才奠定了基础。

A Numerical Study on Effects of Land-Surface Heterogeneity from' Combined Approach' on Atmospheric ProcessPart II: Coupling-Model Simulations

Two land surface schemes, one the standard Biosphere / Atmosphere Transfer Scheme Version ie (BOZ) and the other B1Z based on B0Z and heterogeneously-treated by' combined approach' , were co 'pled to the meso-scale model MM4, respectively. Through the calculations of equations from the companion paper, parameters representing land surface heterogeneity and suitable for the coupling models were found out. Three cases were simulated for heavy rainfalls during 36 hours, and the sensitivity of short-term weather modeling to the land surface heterogeneity was tested. Through the analysis of the simulations of the three heavy rainfalls, it was demonstrated that BIZ, compared with BOZ, could more realistically reflect the features of the land surface heterogeneity, therefore could more realistically reproduce the circulation and precipitation amount in the heavy rainfall processes of the three cases. This shows that even short-term weather is sensitive to the land surface heterogeneity, which is more obvious with time passing, and whose influence is more pronounced in the lower layer and gradually extends to the middle and upper layer. Through the analysis of these simulations with BlZ, it is suggested that the bulk effect of smaller-scale fluxes (i.e., the momentum, water vapor and sensible heat fluxes) near the s ig nificantly-heterogeneous land surface is to change the larger-scale (i.e., meso-scale) circulation, and then to influence the development of the low-level jets and precipitation. And also, the complexity of the land-atmosphere interaction was shown in these simulations.

Study on Wave Dissipation of the Structure Combined by Baffle and Submerged Breakwater

This paper proposes a structure combined by baffle and submerged breakwater （abbreviated to SCBSB in the following texts）. Such a combined structure is conducive to the water exchange in the harbor, and has strong capability on wave dissipation. Our paper focuses on the discussion of two typical structures, i.e., the submerged baffle and rectangular breakwater combined with the upper baffle respectively, which are named as SCBSB 1 and SCBSB2 for short. The eigenfunction method corrected by experimental results is used to investigate the wave dissipation characteristics. It shows that the calculated results agree well with the experimental data and the minimum value of the wave transmission coefficient can be obtained when the distance between the front and rear structures is from 1/4 to 1/2 of the incident wave length.

A Numerical Study on Effects of Land-Surface Heterogeneity from "Combined Approach" on Atmospheric Process Part I: Principle and Method

A method based on Giorgi (1997a, 1997b) and referred to as ’ combined approach’, which is a combi-nation of mosaic approach and analytical-statistical-dynamical approach, is proposed. Compared with those of other approaches, the main advantage of the combined approach is that it not only can represent both interpatch and intrapatch variability, but also cost less computational time when the land surface heterogeneity is considered. Because the independent variable of probability density function (PDF) is ex-tended to the single valued function of basic meteorological characteristic quantities, which is much more universal, the analytical expressions of the characteristic quantities (e.g., drag coefficient, snow coverage, leaf surface aerodynamical resistance) affected by roughness length are derived , when the roughness length(and / or the zero plane displacement) heterogeneity has been mainly taken into account with the approach. On the basis of the rule which the PDF parameters should follow, we choose a function y of the roughness length z 0 as the PDF independent variable, and set different values of the two parameters width ratio αn and height ratio γ of PDF (here a linear, symmetric PDF is applied) for sensitivity experiments, from which some conclusions can be drawn, e.g., relevant characteristic terms show different sensitivities to the heterogeneous characteristic (i.e., roughness length), which suggests that we should consider the heterogeneities of the more sensitive terms in our model instead of the heterogeneities of the rest, and which also implies that when the land surface scheme is coupled into the global or regional atmospheric model, sensitivity tests against the distribution of the heterogeneous characteristic are very necessary; when the parameter αn is close to zero, little heterogeneity is represented, and αn differs with cases, which have an upper limit of about 0.6; in the reasonable range of αn, a peak-like distribution of roughness length can be depicted by a small value of γ, etc.. Key words Representation of land surface heterogeneity - “ Combined approach” - Numerical experiment This work was supported by the National Sciences Foundation of China, Grant No.49875005 and the State Key Project (973) G19990434 (03).

Research on Recreational Intention and Experience in Tourism-Take Nantou Ancient City as an Example

In recent years,under the guidance of the national“all-for-one tourism”and“integration of culture and tourism”development policies,humanistic leisure tourism has become the current hot spot in the development of Chinese tourism industry.In 2013,China promulgated the National Tourism and Leisure Outline(2013-2020),which boosted the development of tourism and leisure consumption of urban and rural residents.In 2016,the State Council issued the“Several Opinions on Further Promoting the Construction of New Urbanization”,which clearly stated that it is necessary to“accelerate the cultivation of characteristic small towns”.The construction of small towns(blocks)led by the integration of culture and tourism has gradually become a new driving force for local economic development.In 2020,the global outbreak of the COVID-19 and normalized prevention and control measures have made the choice of tourism and leisure destinations more localized and short-distance.Characteristic leisure blocks and small towns have increasingly become important destinations for people to travel and leisure activities.Therefore,this article takes Shenzhen Nantou Ancient City as the research area,and uses literature review,questionnaire survey,and statistical survey methods(SPSS.25 and PLS.3.0)to obtain relevant literature and data and describe them.Statistical analysis and confirmatory factor analysis are designed to examine the relationship between the cultural authenticity of leisure blocks,product combination,accessibility,the sense of place identification,recreational intentions,and experience quality,diagnose and discover tourism from them,discover the problems existing on the supply side of tourism object,and provide guidance and suggestions for the construction and development of cultural tourism and leisure characteristic blocks.Finally,this paper tests 10 hypotheses and draws research conclusions:(1)Cultural authenticity has positive impact on recreational intention,place identification,and experience quality in humanistic leisure tourism.(2)Tourism product combination has positive impact on recreational intention and experience quality.(3)Accessibility can affect recreational intention and experience quality in a positive way.(4)Place identification can affect recreational intention in a positive way.(5)Experience quality has positive impact on recreational intention and place identification.

生物科学与技术虚拟仿真实验教学中心的建设与应用

生物科学与技术虚拟仿真实验教学中心通过优秀科研项目转化以及与高新技术企业合作开发,建设了一批高质量的生物类虚拟仿真实验教学资源。多层次、多元化的资源为学生前沿科学知识学习、综合性科研训练和生物下游产业技术训练提供有利环境,有效地实现教学模式的转变以及学科交叉知识的学习和延伸。全天候开放共享虚拟仿真实验教学平台,实现虚拟仿真实验教学软件、实验标准化视频、教学课件和测试题库等线上教学资源的有机整合,满足随时随地实验教学需求,支持了一系列的混合式线上线下实验教学课程开展。生物科学与技术虚拟仿真实验教学中心与国家级生物科学实验教学示范中心形成了“双中心”融合发展的创新人才培养实验教学体系,“虚实结合”的实验教学模式,提升了学生的综合科研能力与教师的业务水平,培养了满足社会需求的生物技术创新实践人才。

基于基础与专业相融合的研究型实验教学方法探索

以卓越工程师教育为背景,针对创新型、实践型工程技术人才培养目标,该文将笔者多年课堂教学、实验教学和相关科研工作的经验融入到实验教学中,探索基础与专业相融合的研究型实验教学方法。方法注重学生对基础知识与专业应用的融合训练,基于基础实验系统和综合开放式实验平台,通过对学生在基础电路测试、知识分解、电路独立设计与测试方面的训练,帮助学生创新性和科学研究素养的培养。该文方法在教学实践中进行应用,并起到较好的效果。

“发酵工程”课程“理论——仿真——实操”教学体系研究

“发酵工程”是生物制药专业开设的一门实践性较强的必修课程。发挥仿真实验教学的链接作用,“理论—仿真—实操”的教学体系实现了理论与实践的有机融合。教学成效分析显示,该教学体系增强了学生的学习兴趣,提高了学生对理论知识的理解能力和应用实践能力,促进了课程目标的达成。

最优尺寸参数对涡流管能量分离效应影响的研究

为确定出涡流管各因素的主次顺序,找出最优的参数组合,提出正交试验设计和极差分析法,找到涡流管能量分离效应的最优化尺寸参数。实验设定涡流管进气温度为26℃,环境温度为27.1℃,结果表明,4个尺寸参数对涡流管能量分离影响排序为:长径比>喷嘴数目>冷端直径>进气压力,每个参数的最优值各为长径比为25.0、喷嘴个数为6、冷端直径为5 mm、进气压力为0.8 MPa,并通过对试验结果的验证,发现涡流管的冷热端出口温差为95.2℃。根据正交试验设计方案找出了涡流管各部件的最优尺寸参数。

许铣教授中西医结合治疗玫瑰痤疮的临证经验

许铣教授从事皮肤科临床、科研工作60余年,中西医结合治疗玫瑰痤疮经验丰富。许铣教授认为,肝郁血热、脾胃湿热为玫瑰痤疮的核心病机。治疗应以中药内服为主,结合疾病分型分期辨证论治,红斑与毛细血管扩张期的基本病因病机为肝失疏泄,郁而化热,基本治法为凉血疏肝兼以养阴清热;丘疹脓疱期主要以脾胃运化失司、脾胃湿热为主,治法为清热燥湿、解毒散结。病程日久者往往合并血瘀和湿热。外治中药常选择具有清热凉血、燥湿、解毒之药效及抑菌、控脂之药理作用的中药。同时,可以根据疾病的临床表现选用西药辅助治疗,临床疗效显著,附验案1例加以佐证。

医疗机构基于“三结合”中药新药研发及管理体系的构建

目的:在中药审评审批制度改革的政策背景下,围绕医疗机构,探索中医药理论、人用经验和临床试验相结合(简称“三结合”)的审评证据体系落地举措,为医疗机构中药制剂及中药新药研发提供参考。方法:根据“三结合”审评证据体系下中药新药研发的相关要求,从机构层面加强人用经验研究相关配套建设,从管理层面搭建中药研发、成果转化服务平台,从临床层面规范开展人用经验研究,构建医疗机构中药新药研发及管理体系。结果:医疗机构中药新药研发及管理体系的构建,有助于将临床诊疗数据转变为支持中药新药注册的人用经验证据,通过提高中药研发水平促进中药新药转化。结论:在医疗机构构建基于“三结合”的中药新药研发及管理体系,是“三结合”审评证据体系落地、政策引导研发实践的路径之一。

基于科教融合的交通工程精品实验建设与实践

为实现培养目标中“能设计及运用现代交通仪器和信息技术对复杂交通工程问题分析和模拟计算”的交通工程专业毕业要求,须利用科教融合手段设计实验方案和构建实验系统,达到“两性一度”的标准要求。以“不同能见度对驾驶安全影响实验”精品实验项目建设为例,介绍了以复杂科研实验萃取为教学实验项目的基本原则,以先进科研装备为手段,遴选科研实验、结合开放实验到最后成功应用至实验教学等环节。实践证明,科教融合的实验教学对学生的人格素养和创新能力培养具有积极作用,学生评教调查表明,基于科教融合的实验教学具有挑战性,能够激发学生深度思考,取得优秀的教学效果。

浪流作用下多船并排锚泊运动量和锚泊力研究

采用物理模型试验方法,对波浪和水流单独和联合作用下,小尺度渔船单船艏艉锚泊和多船并排艏艉锚泊时各船的运动量和锚泊力进行研究,重点分析了90°横浪横流和0°顺浪顺流两个方向锚泊时流对各船运动量和锚泊力的影响程度。研究结果表明,90°浪流作用时单船的横摇角度同纯浪作用时相比减少30%~60%,多船时各船横摇角度减少10%~70%;当波浪入射周期接近单船横摇周期时,浪流作用下单船的锚泊力约为纯浪作用结果的1.11倍,且随着波浪入射周期的继续增大,流的影响明显增大。0°浪流作用时,并排锚泊渔船各船的纵摇角度同纯浪作用相比减少20%~40%,而各船锚泊力则为纯浪作用结果的1.6~10.0倍,但仍小于90°浪流作用时的对应值。因此,当港内存在浪流同向作用时,建议尽量以0°方向并排锚泊渔船;如果确需90°方向锚泊时,应加强迎浪侧和背浪侧渔船的缆绳强度并关注背浪侧渔船的运动量情况。

基于名中医经验的中医辨证组方治疗老年慢性肾炎(CKD1~3a期)患者随机对照研究

目的:观察基于名中医经验的中医辨证组方对老年慢性肾炎(CKD1-3a期)患者的有效性和安全性。方法:将84例老年慢性肾炎患者随机分成治疗组(42例)和对照组(42例)。治疗组采用西医基础联合中医辨证组方治疗;对照组仅接受西医基础治疗,疗程均为24周。观察两组治疗前后24 h尿蛋白定量(24 h UPQ)、肾小球滤过率(eGFR)等临床指标变化,以及疗效和安全性。结果:与本组基线比较,两组治疗后12、18、24周24 h UPQ均显著下降(P<0.01),且24周时治疗组优于对照组(P<0.01)。治疗组总有效率为67.57%,对照组总有效率41.67%,治疗组显著高于对照组(P<0.05)。将慢性肾脏病(CKD)3a期患者进行亚组分析提示,24周后治疗组eGFR较本组基线及同期对照组显著升高(P<0.01,P<0.05),而对照组治疗前后无显著变化。治疗组不良反应发生4例,对照组2例,两组无严重不良反应出现。结论:基于名中医经验的中医辨证组方治疗老年慢性肾炎(CKD1-3a期),可减少尿蛋白,提高临床疗效,对其中的CKD3a期患者可能具有改善eGFR作用,且安全性较好。

电网优化调度的模型-数据-知识融合方法研究评述及展望

随着新型电力系统时变不确定因素日益增多和非线性更为增强,电网调度决策的复杂度剧增,充分利用物理模型、数据驱动和调度员知识经验的互补特性,有望实现电网优化调度决策效率和场景适应性的提升。首先,从不确定性调度、数据驱动和知识驱动3方面分别梳理了电网优化调度相关新发展;其次,分析了模型-数据-知识融合的内涵,将3者融合架构分为主从驱动模式和对等驱动模式,分别评述了国内外学者的相关研究工作;最后,针对模型-数据-知识融合在电网优化调度中的应用现状分析了存在问题,并从模型-数据-知识融合效果的量化评价、调度可信知识的主动筛选和演绎、多模式融合的电网调度可靠智能决策和自主趋优演化4个方面对未来研究方向进行了展望。