Objective:To report a case of anisometropic amblyopia reversal as a result of branch retinal vein occlusion (BRVO) occurring in the sound fellow eye.Methods:An adult patient with childhood anisometropic amblyopia was ...Objective:To report a case of anisometropic amblyopia reversal as a result of branch retinal vein occlusion (BRVO) occurring in the sound fellow eye.Methods:An adult patient with childhood anisometropic amblyopia was found to exhibit gradually visual acuity improvement in the amblyopic eye as the result of decreased visual acuity in the sound fellow eye.Results:Four years after the BRVO,the patient subsequently regained normal vision in the previously amblyopic eye.Conclusion:Visual plasticity is preserved in adults but may require special or stronger stimulation and possibly longer treatment time than during childhood.展开更多
Amblyopia is a neurodevelopmental vision disorder resulting from abnormal visual input during the critical period of visual development,such as strabismus,uncorrected anisometropia,high refractive errors,and form depr...Amblyopia is a neurodevelopmental vision disorder resulting from abnormal visual input during the critical period of visual development,such as strabismus,uncorrected anisometropia,high refractive errors,and form deprivation.It is frequently associated with reduced visual acuity and deficits in binocular vision.Traditional occlusion therapy for amblyopia has typically been restricted to infants and young children during the critical period of visual development,as it is believed to be ineffective for older children and adults due to the decreased plasticity of the mature brain.Our research group has concentrated on pivotal scientific issues in amblyopia,including quantitative methods for detecting binocular vision,especially interocular visual suppression,the mechanisms underlying binocular vision impairment in amblyopia,treatment methods and their evaluations for amblyopia,and visual plasticity and its neural mechanisms in amblyopia.This paper summarizes the visual mechanisms and treatment modalities of amblyopia based on our research and both domestic and foreign sources,while also looking forward to the future development of this field in light of existing problems.展开更多
文摘Objective:To report a case of anisometropic amblyopia reversal as a result of branch retinal vein occlusion (BRVO) occurring in the sound fellow eye.Methods:An adult patient with childhood anisometropic amblyopia was found to exhibit gradually visual acuity improvement in the amblyopic eye as the result of decreased visual acuity in the sound fellow eye.Results:Four years after the BRVO,the patient subsequently regained normal vision in the previously amblyopic eye.Conclusion:Visual plasticity is preserved in adults but may require special or stronger stimulation and possibly longer treatment time than during childhood.
基金supported by the National Natural Science Foundation of China(82271115,82471115)the Natural Science Foundation Team Project of Guangdong Province Grant(2015A030312016).
文摘Amblyopia is a neurodevelopmental vision disorder resulting from abnormal visual input during the critical period of visual development,such as strabismus,uncorrected anisometropia,high refractive errors,and form deprivation.It is frequently associated with reduced visual acuity and deficits in binocular vision.Traditional occlusion therapy for amblyopia has typically been restricted to infants and young children during the critical period of visual development,as it is believed to be ineffective for older children and adults due to the decreased plasticity of the mature brain.Our research group has concentrated on pivotal scientific issues in amblyopia,including quantitative methods for detecting binocular vision,especially interocular visual suppression,the mechanisms underlying binocular vision impairment in amblyopia,treatment methods and their evaluations for amblyopia,and visual plasticity and its neural mechanisms in amblyopia.This paper summarizes the visual mechanisms and treatment modalities of amblyopia based on our research and both domestic and foreign sources,while also looking forward to the future development of this field in light of existing problems.