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Global trends and hotspots of type 2 diabetes in children and adolescents:A bibliometric study and visualization analysis
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作者 Fang-Shuo Zhang Hai-Jing Li +7 位作者 Xue Yu Yi-Ping Song Yan-Feng Ren Xuan-Zhu Qian Jia-Li Liu Wen-Xun Li Yi-Ran Huang Kuo Gao 《World Journal of Diabetes》 SCIE 2025年第1期140-168,共29页
BACKGROUND Epidemiological surveys indicate an increasing incidence of type 2 diabetes mellitus(T2DM)among children and adolescents worldwide.Due to rapid disease progression,severe long-term cardiorenal complications... BACKGROUND Epidemiological surveys indicate an increasing incidence of type 2 diabetes mellitus(T2DM)among children and adolescents worldwide.Due to rapid disease progression,severe long-term cardiorenal complications,a lack of effective treatment strategies,and substantial socioeconomic burdens,it has become an urgent public health issue that requires management and resolution.Adolescent T2DM differs from adult T2DM.Despite a significant increase in our understanding of youth-onset T2DM over the past two decades,the related review and evidence-based content remain limited.AIM To visualize the hotspots and trends in pediatric and adolescent T2DM research and to forecast their future research themes.METHODS This study utilized the terms“children”,“adolescents”,and“type 2 diabetes”,retrieving relevant articles published between 1983 and 2023 from three citation databases within the Web of Science Core Collection(SCI,SSCI,ESCI).Utilizing CiteSpace and VoSviewer software,we analyze and visually represent the annual output of literature,countries involved,and participating institutions.This allows us to predict trends in this research field.Our analysis encompasses co-cited authors,journal overlays,citation overlays,time-zone views,keyword analysis,and reference analysis,etc.RESULTS A total of 9210 articles were included,and the annual publication volume in this field showed a steady growth trend.The United States had the highest number of publications and the highest H-index.The United States also had the most research institutions and the strongest research capacity.The global hot journals were primarily diabetes professional journals but also included journals related to nutrition,endocrinology,and metabolism.Keyword analysis showed that research related to endothelial dysfunction,exposure risk,cardiac metabolic risk,changes in gut microbiota,the impact on comorbidities and outcomes,etc.,were emerging keywords.They have maintained their popularity in this field,suggesting that these areas have garnered significant research interest in recent years.CONCLUSION Pediatric and adolescent T2DM is increasingly drawing global attention,with genes,behaviors,environmental factors,and multisystemic interventions potentially emerging as future research hot spots. 展开更多
关键词 CHILD ADOLESCENT Type 2 diabetes mellitus BIBLIOMETRICS Knowledge mapping visualization CiteSpace VOSviewer
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Three-dimensional visualization technology for guiding one-step percutaneous transhepatic cholangioscopic lithotripsy for the treatment of complex hepatolithiasis 被引量:1
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作者 Yong-Qing Ye Ya-Wen Cao +6 位作者 Rong-Qi Li En-Ze Li Lei Yan Zhao-Wei Ding Jin-Ming Fan Ping Wang Yi-Xiang Wu 《World Journal of Gastroenterology》 SCIE CAS 2024年第28期3393-3402,共10页
BACKGROUND Biliary stone disease is a highly prevalent condition and a leading cause of hospitalization worldwide.Hepatolithiasis with associated strictures has high residual and recurrence rates after traditional mul... BACKGROUND Biliary stone disease is a highly prevalent condition and a leading cause of hospitalization worldwide.Hepatolithiasis with associated strictures has high residual and recurrence rates after traditional multisession percutaneous transhepatic cholangioscopic lithotripsy(PTCSL).AIM To study one-step PTCSL using the percutaneous transhepatic one-step biliary fistulation(PTOBF)technique guided by three-dimensional(3D)visualization.METHODS This was a retrospective,single-center study analyzing,140 patients who,between October 2016 and October 2023,underwent one-step PTCSL for hepatolithiasis.The patients were divided into two groups:The 3D-PTOBF group and the PTOBF group.Stone clearance on choledochoscopy,complications,and long-term clearance and recurrence rates were assessed.RESULTS Age,total bilirubin,direct bilirubin,Child-Pugh class,and stone location were similar between the 2 groups,but there was a significant difference in bile duct strictures,with biliary strictures more common in the 3D-PTOBF group(P=0.001).The median follow-up time was 55.0(55.0,512.0)days.The immediate stone clearance ratio(88.6%vs 27.1%,P=0.000)and stricture resolution ratio(97.1%vs 78.6%,P=0.001)in the 3D-PTOBF group were significantly greater than those in the PTOBF group.Postoperative complication(8.6%vs 41.4%,P=0.000)and stone recurrence rates(7.1%vs 38.6%,P=0.000)were significantly lower in the 3D-PTOBF group.CONCLUSION Three-dimensional visualization helps make one-step PTCSL a safe,effective,and promising treatment for patients with complicated primary hepatolithiasis.The perioperative and long-term outcomes are satisfactory for patients with complicated primary hepatolithiasis.This minimally invasive method has the potential to be used as a substitute for hepatobiliary surgery. 展开更多
关键词 HEPATOLITHIASIS One-step percutaneous transhepatic cholangioscopic lithotripsy Biliary disease Three-dimensional visualization Clinical efficacy
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Instance Segmentation of Characters Recognized in Palmyrene Aramaic Inscriptions
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作者 Adéla Hamplová Alexey Lyavdansky +3 位作者 TomášNovák Ondrej Svojše David Franc Arnošt Veselý 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第9期2869-2889,共21页
This study presents a single-class and multi-class instance segmentation approach applied to ancient Palmyrene inscriptions,employing two state-of-the-art deep learning algorithms,namely YOLOv8 and Roboflow 3.0.The go... This study presents a single-class and multi-class instance segmentation approach applied to ancient Palmyrene inscriptions,employing two state-of-the-art deep learning algorithms,namely YOLOv8 and Roboflow 3.0.The goal is to contribute to the preservation and understanding of historical texts,showcasing the potential of modern deep learning methods in archaeological research.Our research culminates in several key findings and scientific contributions.We comprehensively compare the performance of YOLOv8 and Roboflow 3.0 in the context of Palmyrene character segmentation—this comparative analysis mainly focuses on the strengths and weaknesses of each algorithm in this context.We also created and annotated an extensive dataset of Palmyrene inscriptions,a crucial resource for further research in the field.The dataset serves for training and evaluating the segmentation models.We employ comparative evaluation metrics to quantitatively assess the segmentation results,ensuring the reliability and reproducibility of our findings and we present custom visualization tools for predicted segmentation masks.Our study advances the state of the art in semi-automatic reading of Palmyrene inscriptions and establishes a benchmark for future research.The availability of the Palmyrene dataset and the insights into algorithm performance contribute to the broader understanding of historical text analysis. 展开更多
关键词 Optical character recognition instance segmentation Palmyrene ancient languages computer vision
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Recent progress in visualization and digitization of coherent transformation structures and application in high-strength steel
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作者 Xuelin Wang Zhenjia Xie +1 位作者 Xiucheng Li Chengjia Shang 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2024年第6期1298-1310,共13页
High-strength steels are mainly composed of medium-or low-temperature microstructures,such as bainite or martensite,with coherent transformation characteristics.This type of microstructure has a high density of disloc... High-strength steels are mainly composed of medium-or low-temperature microstructures,such as bainite or martensite,with coherent transformation characteristics.This type of microstructure has a high density of dislocations and fine crystallographic structural units,which ease the coordinated matching of high strength,toughness,and plasticity.Meanwhile,given its excellent welding perform-ance,high-strength steel has been widely used in major engineering constructions,such as pipelines,ships,and bridges.However,visual-ization and digitization of the effective units of these coherent transformation structures using traditional methods(optical microscopy and scanning electron microscopy)is difficult due to their complex morphology.Moreover,the establishment of quantitative relationships with macroscopic mechanical properties and key process parameters presents additional difficulty.This article reviews the latest progress in microstructural visualization and digitization of high-strength steel,with a focus on the application of crystallographic methods in the development of high-strength steel plates and welding.We obtained the crystallographic data(Euler angle)of the transformed microstruc-tures through electron back-scattering diffraction and combined them with the calculation of inverse transformation from bainite or martensite to austenite to determine the reconstruction of high-temperature parent austenite and orientation relationship(OR)during con-tinuous cooling transformation.Furthermore,visualization of crystallographic packets,blocks,and variants based on actual OR and digit-ization of various grain boundaries can be effectively completed to establish quantitative relationships with alloy composition and key process parameters,thereby providing reverse design guidance for the development of high-strength steel. 展开更多
关键词 high-strength steel MICROSTRUCTURE visualization DIGITIZATION quantification mechanical properties
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Application of Landscape Engineering based on BIM Visualization Technology
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作者 LI Yinan OU Xueni DING Juan 《Journal of Landscape Research》 2024年第5期10-14,共5页
The rapid advancement of building information modeling(BIM)technology has garnered significant interest regarding its application within the domain of landscape engineering.BIM technology,as a construction and managem... The rapid advancement of building information modeling(BIM)technology has garnered significant interest regarding its application within the domain of landscape engineering.BIM technology,as a construction and management tool that integrates digitization and visualization,has demonstrated considerable advantages in enhancing project quality,reducing costs,and improving collaborative efficiency.This study aims to systematically investigate the application and developmental trends of BIM visualization technology within the field of landscape engineering.Through an analysis of technological advancements and industry dynamics over the past decade,it has been observed that BIM visualization technology is intricately linked with green building practices,sustainable construction methods,and the development of smart cities within the context of landscape engineering projects.The technology also possesses significant potential for application in the planning and design of landscape engineering,construction management,and project maintenance.The convenience of visualization enhances the expressive capacity of the design scheme,improves communication efficiency between the involved parties,and mitigates the costs and time inefficiencies associated with design modifications.By drawing on the successful experiences of other industries and integrating them with the unique characteristics of landscape engineering,BIM visualization technology is poised to assume a more significant role within this field.This integration is expected to advance the entire industry towards greater intelligence and informatization,while simultaneously enhancing the efficiency and quality of design,construction,and maintenance processes. 展开更多
关键词 BIM visualization technology Landscape engineering visualization application
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Utility of real-time 3D visualization system in the early stage of phacoemulsification training
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作者 Zhe Xu Dan Chen +4 位作者 Jing-Wei Xu Yi-Xuan Feng Ce Shi Li Zhang Wen Xu 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第3期577-582,共6页
●AIM:To determine the teaching effects of a real-time three dimensional(3D)visualization system in the operating room for early-stage phacoemulsification training.●METHODS:A total of 10 ophthalmology residents of th... ●AIM:To determine the teaching effects of a real-time three dimensional(3D)visualization system in the operating room for early-stage phacoemulsification training.●METHODS:A total of 10 ophthalmology residents of the first-year postgraduate were included.All the residents were novices to cataract surgery.Real-time cataract surgical observations were performed using a custom-built 3D visualization system.The training lasted 4wk(32h)in all.A modified International Council of Ophthalmology’s Ophthalmology Surgical Competency Assessment Rubric(ICO-OSCAR)containing 4 specific steps of cataract surgery was applied.The self-assessment(self)and expert-assessment(expert)were performed through the microsurgical attempts in the wet lab for each participant.●RESULTS:Compared with pre-training assessments(self 3.2±0.8,expert 2.5±0.6),the overall mean scores of posttraining(self 5.2±0.4,expert 4.7±0.6)were significantly improved after real-time observation training of 3D visualization system(P<0.05).Scores of 4 surgical items were significantly improved both self and expert assessment after training(P<0.05).●CONCLUSION:The 3D observation training provides novice ophthalmic residents with a better understanding of intraocular microsurgical techniques.It is a useful tool to improve teaching efficiency of surgical education. 展开更多
关键词 3D visualization system phacoemulsification training wet lab
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From Society to Solitude:An In-depth Analysis of Thoreau’s Characters in Walden
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作者 LU Xiao-jun GONG Yu-miao 《Journal of Literature and Art Studies》 2024年第10期898-903,共6页
With the deterioration of the environment and the unbalanced relationship between man and nature,people are plagued by varieties of social problems and rising spiritual crises.This paper aims to analyze Thoreau’s cha... With the deterioration of the environment and the unbalanced relationship between man and nature,people are plagued by varieties of social problems and rising spiritual crises.This paper aims to analyze Thoreau’s characters in Walden and attempts to provide the implications for our contemporary life.Combined with Thoreau’s life experience and the background of Walden,the paper starts with the analysis of Thoreau’s characters from three aspects concerning his pursuit of inner serenity,search for true essence of life and abiding passion for life,which constitute his unique and independent characters and provide the enlightenment for contemporary life.We concluded that unique thoughts,attitudes,and spirit embedded in Thoreau’s characters are inextricably connected with our contemporary life.His personal experience and practice of solitary life at Walden Pond is a testimony to the necessity of closing to nature actively and confronting life passionately. 展开更多
关键词 THOREAU WALDEN SOLITUDE characters enlightenment for life
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Research fronts and researchers of World Journal of Psychiatry in 2023: A visualization and analysis of mapping knowledge domains
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作者 Yun-Tian Xie Yu-Jing Yang 《World Journal of Psychiatry》 SCIE 2024年第7期1118-1126,共9页
BACKGROUND In the rapidly evolving landscape of psychiatric research,2023 marked another year of significant progress globally,with the World Journal of Psychiatry(WJP)experiencing notable expansion and influence.AIM ... BACKGROUND In the rapidly evolving landscape of psychiatric research,2023 marked another year of significant progress globally,with the World Journal of Psychiatry(WJP)experiencing notable expansion and influence.AIM To conduct a comprehensive visualization and analysis of the articles published in the WJP throughout 2023.By delving into these publications,the aim is to deter-mine the valuable insights that can illuminate pathways for future research endeavors in the field of psychiatry.METHODS A selection process led to the inclusion of 107 papers from the WJP published in 2023,forming the dataset for the analysis.Employing advanced visualization techniques,this study mapped the knowledge domains represented in these papers.RESULTS The findings revealed a prevalent focus on key topics such as depression,mental health,anxiety,schizophrenia,and the impact of coronavirus disease 2019.Additionally,through keyword clustering,it became evident that these papers were predominantly focused on exploring mental health disorders,depression,anxiety,schizophrenia,and related factors.Noteworthy contributions hailed authors in regions such as China,the United Kingdom,United States,and Turkey.Particularly,the paper garnered the highest number of citations,while the American Psychiatric Association was the most cited reference.CONCLUSION It is recommended that the WJP continue in its efforts to enhance the quality of papers published in the field of psychiatry.Additionally,there is a pressing need to delve into the potential applications of digital interventions and artificial intelligence within the discipline. 展开更多
关键词 World Journal of Psychiatry PSYCHIATRY Mapping knowledge domains visualization ANALYSIS
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Evaluating the use of three-dimensional reconstruction visualization technology for precise laparoscopic resection in gastroesophageal junction cancer
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作者 Dan Guo Xiao-Yan Zhu +2 位作者 Shuai Han Yu-Shu Liu Da-Peng Cui 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第5期1311-1319,共9页
BACKGROUND Laparoscopic gastrectomy for esophagogastric junction(EGJ)carcinoma enables the removal of the carcinoma at the junction between the stomach and esophagus while preserving the gastric function,thereby provi... BACKGROUND Laparoscopic gastrectomy for esophagogastric junction(EGJ)carcinoma enables the removal of the carcinoma at the junction between the stomach and esophagus while preserving the gastric function,thereby providing patients with better treatment outcomes and quality of life.Nonetheless,this surgical technique also presents some challenges and limitations.Therefore,three-dimensional reconstruction visualization technology(3D RVT)has been introduced into the procedure,providing doctors with more comprehensive and intuitive anatomical information that helps with surgical planning,navigation,and outcome evaluation.AIM To discuss the application and advantages of 3D RVT in precise laparoscopic resection of EGJ carcinomas.METHODS Data were obtained from the electronic or paper-based medical records at The First Affiliated Hospital of Hebei North University from January 2020 to June 2022.A total of 120 patients diagnosed with EGJ carcinoma were included in the study.Of these,68 underwent laparoscopic resection after computed tomography(CT)-enhanced scanning and were categorized into the 2D group,whereas 52 underwent laparoscopic resection after CT-enhanced scanning and 3D RVT and were categorized into the 3D group.This study had two outcome measures:the deviation between tumor-related factors(such as maximum tumor diameter and infiltration length)in 3D RVT and clinical reality,and surgical outcome indicators(such as operative time,intraoperative blood loss,number of lymph node dissections,R0 resection rate,postoperative hospital stay,postoperative gas discharge time,drainage tube removal time,and related complications)between the 2D and 3D groups.RESULTS Among patients included in the 3D group,27 had a maximum tumor diameter of less than 3 cm,whereas 25 had a diameter of 3 cm or more.In actual surgical observations,24 had a diameter of less than 3 cm,whereas 28 had a diameter of 3 cm or more.The findings were consistent between the two methods(χ^(2)=0.346,P=0.556),with a kappa consistency coefficient of 0.808.With respect to infiltration length,in the 3D group,23 patients had a length of less than 5 cm,whereas 29 had a length of 5 cm or more.In actual surgical observations,20 cases had a length of less than 5 cm,whereas 32 had a length of 5 cm or more.The findings were consistent between the two methods(χ^(2)=0.357,P=0.550),with a kappa consistency coefficient of 0.486.Pearson correlation analysis showed that the maximum tumor diameter and infiltration length measured using 3D RVT were positively correlated with clinical observations during surgery(r=0.814 and 0.490,both P<0.05).The 3D group had a shorter operative time(157.02±8.38 vs 183.16±23.87),less intraoperative blood loss(83.65±14.22 vs 110.94±22.05),and higher number of lymph node dissections(28.98±2.82 vs 23.56±2.77)and R0 resection rate(80.77%vs 61.64%)than the 2D group.Furthermore,the 3D group had shorter hospital stay[8(8,9)vs 13(14,16)],time to gas passage[3(3,4)vs 4(5,5)],and drainage tube removal time[4(4,5)vs 6(6,7)]than the 2D group.The complication rate was lower in the 3D group(11.54%)than in the 2D group(26.47%)(χ^(2)=4.106,P<0.05).CONCLUSION Using 3D RVT,doctors can gain a more comprehensive and intuitive understanding of the anatomy and related lesions of EGJ carcinomas,thus enabling more accurate surgical planning. 展开更多
关键词 Gastroesophageal junction cancer ENDOSCOPY Tumor resection Three-dimensional reconstruction visualization Two-dimensional imaging computed tomography
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Development,hotspots and trend directions of groundwater numerical simulation:A bibliometric and visualization analysis
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作者 Liu Yang Yan-pei Cheng +1 位作者 Xue-ru Wen Jun Liu 《Journal of Groundwater Science and Engineering》 2024年第4期411-427,共17页
Groundwater is a vital component of the hydrological cycle and essential for the sustainable development of ecosystems.Numerical simulation methods are key tools for addressing scientific challenges in groundwater res... Groundwater is a vital component of the hydrological cycle and essential for the sustainable development of ecosystems.Numerical simulation methods are key tools for addressing scientific challenges in groundwater research.This study uses bibliometric visualization analysis to examine the progress and trends in groundwater numerical simulation methods.By analyzing literature indexed in the Web of Science database from January 1990 to February 2023,and employing tools such as Citespace and VOSviewer,we assessed publication volume,research institutions and their collaborations,prolific scholars,keyword clustering,and emerging trends.The findings indicate an overall upward trend in both the number of publications and citations concerning groundwater numerical simulations.Since 2010,the number of publications has tripled compared to the total before 2010,underscoring the increasing significance and potential of numerical simulation methods in groundwater science.China,in particular,has shown remarkable growth in this field over the past decade,surpassing the United States,Canada,and Germany.This progress is closely linked to strong national support and active participation from research institutions,especially the contributions from teams at Hohai University,China University of Geosciences,and the University of Science and Technology of China.Collaboration between research teams is primarily seen between China and the United States,with less noticeable cooperation among other countries,resulting in a diverse and dispersed development pattern.Keyword analysis highlights that international research hotspots include groundwater recharge,karst water,geothermal water migration,seawater intrusion,variable density flow,contaminant and solute transport,pollution remediation,and land subsidence.Looking ahead,groundwater numerical simulations are expected to play a more prominent role in areas such as climate change,surface water-groundwater interactions,the impact of groundwater nitrates on the environment and health,submarine groundwater discharge,ecological water use,groundwater management,and risk prevention. 展开更多
关键词 CLUSTERING visualization analysis Groundwater numerical simulation Ecological water use Groundwater management
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The gas discharge visualization(GDV)order parameter model based on the principle of mastering both permanence and change
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作者 XIN Yu ZHANG Lei +3 位作者 ZHAO Qiancheng SHE Yurong SHE Zhensu SONG Shuna 《Digital Chinese Medicine》 CAS CSCD 2024年第3期231-240,共10页
Objective To investigate the human body’s complex system,and classify and characterize the human body’s health states with“a comprehensive integrated method from qualitative to quantitative”.Methods This paper int... Objective To investigate the human body’s complex system,and classify and characterize the human body’s health states with“a comprehensive integrated method from qualitative to quantitative”.Methods This paper introduces the concept of“order parameters”and proposes a method for establishing an order parameter model of gas discharge visualization(GDV)based on the principle of“mastering both permanence and change(MBPC)”.The method involved the fol-lowing three steps.First,average luminous intensity(I)and average area(S)of the GDV im-ages were calculated to construct the phase space,and the score of the health questionnaire was calculated as the health deviation index(H).Second,the k-means++clustering method was employed to identify subclasses with the same health characteristics based on the data samples,and to statistically determine the symptom-specific frequencies of the subclasses.Third,the distance(d)between each sample and the“ideal health state”,which determined in the phase space of each subclass,was calculated as an order parameter describing the health imbalance,and a linear mapping was established between the d and the H.Further,the health implications of GDV signals were explored by analyzing subclass symptom profiles.We also compare the mean square error(MSE)with classification methods based on age,gen-der,and body mass index(BMI)indices to verify that the phase space possesses the ability to portray the health status of the human body.Results This study preliminarily tested the reliability of the order parameter model on data samples provided by 20 participants.Based on the discovered linear law,the current model can use d calculated by measuring the GDV signal to predict H(R^(2)>0.77).Combined with the symptom profiles of the subclasses,we explain the classification basis of the phase space based on the pattern identification.Compared with common classification methods based on age,gender,BMI,etc.,the MSE of phase space-based classification was reduced by an order of magnitude.Conclusion In this study,the GDV order parameter model based on MBPC can identify sub-classes and characterize individual health levels,and explore the TCM health meanings of the GDV signals by using subjective-objective methods,which holds significance for establishing mathematical models from TCM diagnosis principles to interpret human body signals. 展开更多
关键词 Gas discharge visualization(GDV) Traditional Chinese medicine(TCM) Order parameters Math-physical model Individualized health assessment
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Research on Visualization and Interactive Design of Plant Configuration Virtual Reality in the Context of Digitalization
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作者 Qiufan Xie 《Journal of Architectural Research and Development》 2024年第3期53-62,共10页
This study aims to explore the application of digital technology in landscape design,focusing on the research of virtual reality visualization and interactive design in the process of plant configuration.Through an in... This study aims to explore the application of digital technology in landscape design,focusing on the research of virtual reality visualization and interactive design in the process of plant configuration.Through an in-depth analysis of digital technology,the study outlines its important role in landscape design,especially in the application of plant configuration.The current application status of virtual reality technology in landscape design is discussed,as well as how interactive design can enhance user experience and participation.Furthermore,the achievements and challenges of digital technology in landscape design are summarized.Finally,it proposes future research directions and suggestions,aiming to provide new ideas and methods for practice and research in the field of landscape design and promote the further application and development of digital technology in landscape design. 展开更多
关键词 lization Plant configuration Virtual reality visualization Interactive design
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Application of Bayesian Analysis Based on Neural Network and Deep Learning in Data Visualization
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作者 Jiying Yang Qi Long +1 位作者 Xiaoyun Zhu Yuan Yang 《Journal of Electronic Research and Application》 2024年第4期88-93,共6页
This study aims to explore the application of Bayesian analysis based on neural networks and deep learning in data visualization.The research background is that with the increasing amount and complexity of data,tradit... This study aims to explore the application of Bayesian analysis based on neural networks and deep learning in data visualization.The research background is that with the increasing amount and complexity of data,traditional data analysis methods have been unable to meet the needs.Research methods include building neural networks and deep learning models,optimizing and improving them through Bayesian analysis,and applying them to the visualization of large-scale data sets.The results show that the neural network combined with Bayesian analysis and deep learning method can effectively improve the accuracy and efficiency of data visualization,and enhance the intuitiveness and depth of data interpretation.The significance of the research is that it provides a new solution for data visualization in the big data environment and helps to further promote the development and application of data science. 展开更多
关键词 Neural network Deep learning Bayesian analysis Data visualization Big data environment
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Comprehensive bibliometric analysis of pharmacotherapy for bipolar disorders:Present trends and future directions
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作者 Bo-Fan Chen Li Liu +13 位作者 Fang-Zhen Lin Hai-Min Zeng Hai-Qiang Huang Chun-Fang Zhang Cong-Cong Liu Xiang Chen Jie Peng Yun-Fa Wang Zhi-Lin Wang Bin Chen De-Le Liu Yun Liu Zheng-Zheng Li Xin-Xing Zeng 《World Journal of Psychiatry》 SCIE 2025年第1期153-167,共15页
BACKGROUND Bipolar disorder(BD)is a severe mental illness characterized by significant mood swings.Effective drug treatment modalities are crucial for managing BD.AIM To analyze the current status and future trends of... BACKGROUND Bipolar disorder(BD)is a severe mental illness characterized by significant mood swings.Effective drug treatment modalities are crucial for managing BD.AIM To analyze the current status and future trends of global research on BD drug treatment over the last decade.METHODS The Web of Science Core Collection database spanning from 2015 to 2024 was utilized to retrieve literature related to BD drug treatment.A total of 2624 articles were extracted.Data visualization and analysis were conducted using CiteSpace,VOSviewer,Pajek,Scimago Graphica,and R-studio bibliometrix to identify RESULTS The United States,China,and the United Kingdom have made the most significant contributions to research on BD drug treatment and formed notable research collaboration networks.The University of Pittsburgh,Massachusetts General Hospital,and the University of Michigan have been identified as the major research institutions in this field.The Journal of Affective Disorders is the most influential journal.A keyword analysis revealed research hotspots related to clinical symptoms,drug efficacy,and genetic mechanisms.A citation analysis identified the management guidelines published by Yatham et al in 2018 as the most cited paper.CONCLUSION This study provides a detailed overview of the field of BD drug treatment,highlighting key contributors,research hotspots,and future directions.The study findings can be employed as a reference for future research and policymaking,which may enable further development and optimization of BD pharmacotherapy. 展开更多
关键词 Bipolar disorder Drug treatment Bibliometric analysis visualization Mental disorder
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Multisensory mechanisms of gait and balance in Parkinson’s disease:an integrative review
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作者 Stiven Roytman Rebecca Paalanen +4 位作者 Giulia Carli Uros Marusic Prabesh Kanel Teus van Laar Nico I.Bohnen 《Neural Regeneration Research》 SCIE CAS 2025年第1期82-92,共11页
Understanding the neural underpinning of human gait and balance is one of the most pertinent challenges for 21st-century translational neuroscience due to the profound impact that falls and mobility disturbances have ... Understanding the neural underpinning of human gait and balance is one of the most pertinent challenges for 21st-century translational neuroscience due to the profound impact that falls and mobility disturbances have on our aging population.Posture and gait control does not happen automatically,as previously believed,but rather requires continuous involvement of central nervous mechanisms.To effectively exert control over the body,the brain must integrate multiple streams of sensory information,including visual,vestibular,and somatosensory signals.The mechanisms which underpin the integration of these multisensory signals are the principal topic of the present work.Existing multisensory integration theories focus on how failure of cognitive processes thought to be involved in multisensory integration leads to falls in older adults.Insufficient emphasis,however,has been placed on specific contributions of individual sensory modalities to multisensory integration processes and cross-modal interactions that occur between the sensory modalities in relation to gait and balance.In the present work,we review the contributions of somatosensory,visual,and vestibular modalities,along with their multisensory intersections to gait and balance in older adults and patients with Parkinson’s disease.We also review evidence of vestibular contributions to multisensory temporal binding windows,previously shown to be highly pertinent to fall risk in older adults.Lastly,we relate multisensory vestibular mechanisms to potential neural substrates,both at the level of neurobiology(concerning positron emission tomography imaging)and at the level of electrophysiology(concerning electroencephalography).We hope that this integrative review,drawing influence across multiple subdisciplines of neuroscience,paves the way for novel research directions and therapeutic neuromodulatory approaches,to improve the lives of older adults and patients with neurodegenerative diseases. 展开更多
关键词 aging BALANCE encephalography functional magnetic resonance imaging GAIT multisensory integration Parkinson’s disease positron emission tomography SOMATOSENSORY VESTIBULAR visual
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Challenges in the management of visual and tactile hallucinations in elderly people
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作者 Si-Sheng Huang 《World Journal of Psychiatry》 SCIE 2025年第1期185-188,共4页
This letter provides a concise review of the pertinent literature on visual and tactile hallucinations in elderly patients.The discussion addresses differential diagnoses and potential underlying mechanisms,as well as... This letter provides a concise review of the pertinent literature on visual and tactile hallucinations in elderly patients.The discussion addresses differential diagnoses and potential underlying mechanisms,as well as the psychopathology associated with tactile hallucinations,and emphasizes the necessity for invest-igation into the possibility of coexisting delusional infestation(parasitosis).These symptoms frequently manifest in patients with primary psychotic disorders,organic mental disorders,and substance use disorders.The proposed pathophy-siological mechanisms may involve dopaminergic imbalances and dysfunction of the striatal dopamine transporter. 展开更多
关键词 Delusional infestation DEMENTIA Haptic hallucination Scratching behavior Tactile hallucination Visual hallucination Alzheimer’s disease
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Application of Mixed Reality Technology in Visualization of Medical Operations 被引量:12
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作者 高原 谭珂 +2 位作者 孙坚 姜涛 邹晓文 《Chinese Medical Sciences Journal》 CAS CSCD 2019年第2期103-109,共7页
With the continuous progress of virtual simulation technology,medical surgery visualization system has been developed from two-dimensional to three-dimensional,from digital to network and intelligentization.The visual... With the continuous progress of virtual simulation technology,medical surgery visualization system has been developed from two-dimensional to three-dimensional,from digital to network and intelligentization.The visualization system with mixed reality technology will also be used in all stage of medical surgery,such as case discussion,surgical planning,intraoperative guidance,post-operative evaluation,rehabilitation,so as to further promote high intelligence,high precision of medical surgery,and consequently improve effectiveness of treatment and quality of medical service.This paper discusses the composition and technical characteristics of medical operation visualization system based on mixed reality technology,and introduces some typical applications of mixed reality technology in medical operation visualization,which provides a new perspective for the application of mixed technology in medical surgery. 展开更多
关键词 MIXED REALITY MEDICAL SURGERY visualization simulation
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Genetic and Correlation Analysis of Grain Characters in Three-line Hybrid Rice 被引量:11
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作者 邹小云 邓辉明 +6 位作者 傅军如 彭小松 朱昌兰 贺晓鹏 陈小荣 贺浩华 刘宜柏 《Agricultural Science & Technology》 CAS 2009年第2期77-81,共5页
Abst[Objective] This study was to understand the genetic dynamics of three-line hybrid rice, and explore the respective effect of sterile line and restoring line on grain characters of hybrid rica. [Method] Four three... Abst[Objective] This study was to understand the genetic dynamics of three-line hybrid rice, and explore the respective effect of sterile line and restoring line on grain characters of hybrid rica. [Method] Four three-line stedle lines and 27 restoring lines(cultivars) commonly culti- vated in Central China region were regarded as expadmental materials to conduct 4 x27NCII cross design, and the grain characters of three-line hybrid rico were analyzed at genetic and correlation levels. [ Result] Four characters of grain length, grain width, 1 000-grain weight and length- width ratio play the leading role in additive gene effect; these four characters were simultaneously influenced by male parent and female parent, but the effect from male parent was relatively larger. The grain length, grain width, 1 000-grain weight and length-width ratio all have high brood hedtabUities( respectively 99.65%, 98.31%, 95.27% and 98.81% ). Correlation analysis showed that grain length was positively correlated with 1 000-grain weight and length-width ratio at extremely significant level; 1 000-grain weight was positively correlated with grain length and length- width ratio at extremely significant level, and was insignificantly correlated with grain width; grain width was negatively correlated with grain length and length-width ratio at extremely significant level. Path analysis showed that the direct path coefficients of grain length, grain width and 1 0(30- grain weight to length-width ratio were 0.624 6, -0.555 9 and -0.015 8, respectively. [ Conclusion] This study systematically analyzed the effects of stedle line and restoring line on grain characters of hybrid rice, which provided theoretical basis for breeding high quality and yield hy- brid dce. 展开更多
关键词 Three-line hybrid dce Grain characters INHERITANCE . Correlation
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Main Agronomic Characters and Grain Quality of Rice Blast Resistance Gene Pi-d2 Transgenic Rice 被引量:6
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作者 陈德西 曲广林 +2 位作者 黄文娟 李婷 李仕贵 《Agricultural Science & Technology》 CAS 2011年第10期1457-1460,共4页
[Objective] The aim of this study was to provide metabolic evidence for the analysis of the ecological and safety assessment of Pi-d2-transgenic rice.[Method] The main agronomic characters of Pi-d2-transgenic rice wer... [Objective] The aim of this study was to provide metabolic evidence for the analysis of the ecological and safety assessment of Pi-d2-transgenic rice.[Method] The main agronomic characters of Pi-d2-transgenic rice were observed in field experiment and the grain chemical characters and amino acid content were measured.[Results] Introduction of foreign gene Pi-d2 resulted in stably hereditable variation in agronomic characteristics in the descents.Most of the transgenic lines grew normally and orderly.Compared with the control(wild type plants),about half of transgenic plants showed an increased or reduced plant height.There was no observable difference between transgenic plants and controls in tiller number,length of panicle,panicles per plant,seed-setting rate and 1 000-grain weight.Total amino acid content in transgenic rice was reduced,while the starch content,GC and GT were not altered in comparison with the control.[Conclusion] Introduction of foreign gene Pi-d2 has remarkable influence on plant height,while little on grain chemical characters. 展开更多
关键词 TRANSGENE Pi-d2 gene Rice Agronomic characters Amino acid
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Correlation Analysis of Characters of Indica Hybrid Rice with High Content of Amylose 被引量:4
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作者 杨扬 况浩池 +4 位作者 曾正明 罗俊涛 陈光珍 何兴材 付均 《Agricultural Science & Technology》 CAS 2013年第3期475-477,共3页
[Objective] The aim was to research and analyze characters and related correlation of indica hybrid rice containing high amylose. [Method] In the research, major characters of 16 species of groups of {ndica hybrid ric... [Objective] The aim was to research and analyze characters and related correlation of indica hybrid rice containing high amylose. [Method] In the research, major characters of 16 species of groups of {ndica hybrid rice and the correlation were explored in rice belts in Sichuan in 2011. [Result] The variation of chalkiness degree was the highest at 26.8%, followed by rate of head rice at 22.89%; varia- tions of head rice rate and chalkiness degree were lower at 0.72% and 2.61%. In addition, rate of unpolished rice was of significantly negative correlation with chalki- ness degree; rate of chalky rice was of extremely positive correlation with chalkiness degree and gel consistency; chalkiness degree was of significantly positive correla- tion with gel consistency; gel consistency was of significantly negative correlation with protein content; amylose content was of insignificant correlation with gel consis- tency (r=0.166 9) of the 16 hybrid groups. These indicated that gel consistency would be still high as the content of amylose grows (AC≥25%). For example, when the content of anylose in Chuanxiang 29A/Luhui 37, Kangfeng AJ6684, and Lefeng A/SR536 exceeded 27%, the gel consistency was over 80 mm in the research. [Conclusion] The research provides references for improvement of amylose content in breeding hybrid rice. 展开更多
关键词 Higher amylose content Indica hybrid rice characters Correlaiton analysis
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