The effect of B_(2)O_(3) content on the viscosity of SiO_(2)−MgO−FeO-based molten slag system was investigated using the rotating cylinder method.The evolution process of the melt structure under different contents of...The effect of B_(2)O_(3) content on the viscosity of SiO_(2)−MgO−FeO-based molten slag system was investigated using the rotating cylinder method.The evolution process of the melt structure under different contents of B_(2)O_(3) was comprehensively studied via FTIR spectroscopy and a model for calculating the degree of polymerization was developed.The results showed that the viscosity of the molten slag decreased with the addition of B_(2)O_(3),which had a slight effect when its content exceeded 3 wt.%.As the addition of B_(2)O_(3) increased from 0 to 4 wt.%,the break temperature of the slags decreased from 1152 to 1050℃ and the apparent activation energy decreased from 157.90 to 141.84 kJ/mol.The addition of B_(2)O_(3) to the molten slag destroyed the chain silicate structure to form a more cyclic borosilicate structure.The Urbain model was improved to calculate the viscosity of the SiO_(2)−MgO−FeO-based slags,and the values were in good agreement with the experimentally measured values.展开更多
目的对叶酸、维生素B_(12)(VB_(12))、二甲双胍联用对2型糖尿病(T2DM)患者的治疗作用。方法选取2021年2月至2023年3月浙江省医疗健康集团长兴医院收治的112例T2DM患者,采用随机数字表法分为对照组(VB_(12)^(+)二甲双胍,56例)和研究组(叶...目的对叶酸、维生素B_(12)(VB_(12))、二甲双胍联用对2型糖尿病(T2DM)患者的治疗作用。方法选取2021年2月至2023年3月浙江省医疗健康集团长兴医院收治的112例T2DM患者,采用随机数字表法分为对照组(VB_(12)^(+)二甲双胍,56例)和研究组(叶酸^(+)VB_(12)^(+)二甲双胍,56例)。对比血糖、糖化血红蛋白(HbA1c)、空腹胰岛素(FINS)水平、胰岛素抵抗指数(HOMA-IR)和同型半胱氨酸(Hcy)水平、临床疗效、CD4^(+)、CD8^(+)、CD4^(+)/CD8^(+)水平、Th1、Th17、Th1/Th17水平,不良反应及并发症。结果治疗后,研究组空腹血糖(FPG)、餐后2 h血糖(2 h PG)、HOMA-IR、HbA1c、FINS和Hcy均低于治疗前与对照组(P<0.05);研究组总有效率更高(P<0.05);治疗后研究组CD4^(+)、CD4^(+)/CD8^(+)均高于治疗前和对照组(P<0.05),CD8^(+)低于治疗前和对照组(P<0.05);治疗后,研究组Th1、Th17水平低于治疗前和对照组(P<0.05),Th1/Th17高于治疗前和对照组(P<0.05);2组患者不良反应发生率比较差异无统计学意义(P>0.05);研究组并发症发生率低于对照组(P<0.05)。结论叶酸与VB_(12)、二甲双胍联用治疗T2DM有助于控糖,还可提高免疫,调节Th1/Th17平衡,且安全可靠,有助于减少并发症。展开更多
基金financially supported by the National Natural Science Foundation of China (No.51774224)。
文摘The effect of B_(2)O_(3) content on the viscosity of SiO_(2)−MgO−FeO-based molten slag system was investigated using the rotating cylinder method.The evolution process of the melt structure under different contents of B_(2)O_(3) was comprehensively studied via FTIR spectroscopy and a model for calculating the degree of polymerization was developed.The results showed that the viscosity of the molten slag decreased with the addition of B_(2)O_(3),which had a slight effect when its content exceeded 3 wt.%.As the addition of B_(2)O_(3) increased from 0 to 4 wt.%,the break temperature of the slags decreased from 1152 to 1050℃ and the apparent activation energy decreased from 157.90 to 141.84 kJ/mol.The addition of B_(2)O_(3) to the molten slag destroyed the chain silicate structure to form a more cyclic borosilicate structure.The Urbain model was improved to calculate the viscosity of the SiO_(2)−MgO−FeO-based slags,and the values were in good agreement with the experimentally measured values.
文摘目的对叶酸、维生素B_(12)(VB_(12))、二甲双胍联用对2型糖尿病(T2DM)患者的治疗作用。方法选取2021年2月至2023年3月浙江省医疗健康集团长兴医院收治的112例T2DM患者,采用随机数字表法分为对照组(VB_(12)^(+)二甲双胍,56例)和研究组(叶酸^(+)VB_(12)^(+)二甲双胍,56例)。对比血糖、糖化血红蛋白(HbA1c)、空腹胰岛素(FINS)水平、胰岛素抵抗指数(HOMA-IR)和同型半胱氨酸(Hcy)水平、临床疗效、CD4^(+)、CD8^(+)、CD4^(+)/CD8^(+)水平、Th1、Th17、Th1/Th17水平,不良反应及并发症。结果治疗后,研究组空腹血糖(FPG)、餐后2 h血糖(2 h PG)、HOMA-IR、HbA1c、FINS和Hcy均低于治疗前与对照组(P<0.05);研究组总有效率更高(P<0.05);治疗后研究组CD4^(+)、CD4^(+)/CD8^(+)均高于治疗前和对照组(P<0.05),CD8^(+)低于治疗前和对照组(P<0.05);治疗后,研究组Th1、Th17水平低于治疗前和对照组(P<0.05),Th1/Th17高于治疗前和对照组(P<0.05);2组患者不良反应发生率比较差异无统计学意义(P>0.05);研究组并发症发生率低于对照组(P<0.05)。结论叶酸与VB_(12)、二甲双胍联用治疗T2DM有助于控糖,还可提高免疫,调节Th1/Th17平衡,且安全可靠,有助于减少并发症。
