AIM: To investigate the changes in vitreous gel structure after lens extirpation combined with anterior vitrectomy in rabbit eyes. METHODS: Twenty-eight chinchilla rabbits were divided into three groups. The contro...AIM: To investigate the changes in vitreous gel structure after lens extirpation combined with anterior vitrectomy in rabbit eyes. METHODS: Twenty-eight chinchilla rabbits were divided into three groups. The control group (Group I) included 16 eyes from eight rabbits who did not receive any treatment. Group II included 20 eyes from 10 rabbits that underwent lens aspiration only. Group III included 20 eyes from 10 rabbits that underwent lens aspiration combined with posterior capsulotomy and anterior vitrectomy. Eyes were harvested on the 30th and 60th day postoperatively, respectively. Changes in vitreous gel stretch length due to gravity and the rate of vitreous liquefaction were observed. The collagen content in the vitreous body was examined using the L-hydroxyproiine test. Electronic microscopic images were obtained from each eyeball. RESULTS: On both the 30th and 60th day postoperatively, the vitreous gel length of group III was significantly shorter than group I and group II (P〈0.05), while the rate of liquefaction of the vitreous body in group III was significantly higher than group I and group II (P〈0.05). The collagen content in group Ul was also higher than that in group I and group II (P〈0.05). CONCLUSION: Loss of vitreous gel mass is more likely to occur in the eyes of rabbits receiving anterior vitrectomy. Lensectomy combined with anterior vitrectomy may damage the stable three-dimensional mesh structure of collagen, which could aggravate vitreous gel liquefaction.展开更多
Spontaneous posterior vitreous detachment(PVD)is a common age-related condition in which prevalence tends to increase with age.Acute PVD can cause the onset of symptoms that include visual disturbances,myodesopsia and...Spontaneous posterior vitreous detachment(PVD)is a common age-related condition in which prevalence tends to increase with age.Acute PVD can cause the onset of symptoms that include visual disturbances,myodesopsia and photopsia.The goal of this short review was to provide a quick glance at the important factors related to PVD based on current literature in this field,which includes incidence,symptoms,diagnosis,risk factors,and education for patients with acute symptoms,and treatments.The take home message is that an ophthalmic examination at the onset of symptoms is of utmost importance,considering that irreversible sight-threatening complications can be prevented if diagnosed and treated promptly.展开更多
基金Supported by Scientific Research Foundation of Health Department in Hubei Province,China(No.CodeJX3B58)
文摘AIM: To investigate the changes in vitreous gel structure after lens extirpation combined with anterior vitrectomy in rabbit eyes. METHODS: Twenty-eight chinchilla rabbits were divided into three groups. The control group (Group I) included 16 eyes from eight rabbits who did not receive any treatment. Group II included 20 eyes from 10 rabbits that underwent lens aspiration only. Group III included 20 eyes from 10 rabbits that underwent lens aspiration combined with posterior capsulotomy and anterior vitrectomy. Eyes were harvested on the 30th and 60th day postoperatively, respectively. Changes in vitreous gel stretch length due to gravity and the rate of vitreous liquefaction were observed. The collagen content in the vitreous body was examined using the L-hydroxyproiine test. Electronic microscopic images were obtained from each eyeball. RESULTS: On both the 30th and 60th day postoperatively, the vitreous gel length of group III was significantly shorter than group I and group II (P〈0.05), while the rate of liquefaction of the vitreous body in group III was significantly higher than group I and group II (P〈0.05). The collagen content in group Ul was also higher than that in group I and group II (P〈0.05). CONCLUSION: Loss of vitreous gel mass is more likely to occur in the eyes of rabbits receiving anterior vitrectomy. Lensectomy combined with anterior vitrectomy may damage the stable three-dimensional mesh structure of collagen, which could aggravate vitreous gel liquefaction.
文摘Spontaneous posterior vitreous detachment(PVD)is a common age-related condition in which prevalence tends to increase with age.Acute PVD can cause the onset of symptoms that include visual disturbances,myodesopsia and photopsia.The goal of this short review was to provide a quick glance at the important factors related to PVD based on current literature in this field,which includes incidence,symptoms,diagnosis,risk factors,and education for patients with acute symptoms,and treatments.The take home message is that an ophthalmic examination at the onset of symptoms is of utmost importance,considering that irreversible sight-threatening complications can be prevented if diagnosed and treated promptly.