A low-power high-swing voltage-mode transmitter

A low-power voltage-mode-logic （VML） transmitter fabricated in TSMC 28 nm CMOS technology is presented. The VML driver outputs a high-swing signal and consumes less power than a current-mode-logic （CML） driver. To further reduce power, the driver is divided into two voltage domains by level shifters. Moreover, the proposed driver topology can achieve mutually decoupled impedance self-calibration and equalization control. The measurement result shows that the transmitter merely dissipates 23 roW/channel while exhibiting an 880 mV differential eye height at 4.488 Gb/s.

Heat stroke alters hippocampal and cerebellar transmitter metabonomics

BACKGROUND:The mechanisms underlying heat stroke(HS)-induced hippocampal injury remain unclear.This study aimed to evaluate the HS-induced metabonomics of hippocampal and cerebellar transmitters.METHODS:The HS model was established with male Sprague-Dawley rats subjected to heat exposure of up to 42℃ at a humidity of(55.0±5.0)%.The hippocampal and cerebellar transmitters and metabolites of rats were tested via ultra-high-performance liquid chromatography–mass spectrometry(UPLC-MS/MS).The primary transmitters and metabolites were identified by principal component analysis(PCA)and orthogonal partial least square-discriminant analysis(OPLS-DA).The major metabolic pathways for HS were selected after enrichment.The brain injury was evaluated by histological tests.RESULTS:HS induced hippocampal and cerebellar injuries in rats.HS upregulated the protein levels of hippocampal glutamate,glutamine,gamma-aminobutyric acid,L-tryptophan(Trp),5-hydroxy-indoleacetic acid,and kynurenine;however,it downregulated asparagine,tryptamine,5-hydroxytryptophan,melatonin,3,4-dihydroxyphenylalanine(L-DOPA),and vanillylmandelic acid.HS also sharply elevated the protein levels of cerebellar methionine and Trp,and decreased the levels of serotonin,L-alanine,L-asparagine,L-aspartate,cysteine,norepinephrine,spermine,spermidine,and tyrosine.Hippocampal glutamate,monoamine transmitters,cerebellar aspartate acid,and catecholamine transmitters’metabolic pathways were identified as the main metablic pathways in HS.CONCLUSION:The hippocampus and cerebellum were injured in rats with HS,possibly induced the disorder of hippocampal glutamate and serotonin metabolism,cerebellar aspartate acid and catecholamine transmitter metabolism,and related metabolic pathways.

Glass-Ceramics with High Strength and High Transmittance Obtained by Multi-Factor Controlling

The presence of Li_(2)Si_(2)O_(5) and LiAlSi_(4)O_(10) could effectively improve the elastic modulus and transmittance of lithium disilicate(LD)glass-ceramics.Through synergistically modulation of the crystal content and grain size,we obtained high strength and high transmittance of LD glass-ceramics.The optimal sample had a high transmittance of 90.3%,the hardness was 7.72 GPa,the fracture toughness was 1.07 MPa·m^(1/2),and the elastic modulus was 103.1 GPa.

SEMI-SUPERVISED RADIO TRANSMITTER CLASSIFICATION BASED ON ELASTIC SPARSITY REGULARIZED SVM

Non-collaborative radio transmitter recognition is a significant but challenging issue, since it is hard or costly to obtain labeled training data samples. In order to make effective use of the unlabeled samples which can be obtained much easier, a novel semi-supervised classification method named Elastic Sparsity Regularized Support Vector Machine (ESRSVM) is proposed for radio transmitter classification. ESRSVM first constructs an elastic-net graph over data samples to capture the robust and natural discriminating information and then incorporate the information into the manifold learning framework by an elastic sparsity regularization term. Experimental results on 10 GMSK modulated Automatic Identification System radios and 15 FM walkie-talkie radios show that ESRSVM achieves obviously better performance than KNN and SVM, which use only labeled samples for classification, and also outperforms semi-supervised classifier LapSVM based on manifold regularization.

Dopamine: an immune transmitter

The dopaminergic system controls several vital central nervous system functions, including the control of movement, reward behaviors and cognition. Alterations of dopaminergic signaling are involved in the pathogenesis of neurodegenerative and psychiatric disorders, in particular Parkinson’s disease, which are associated with a subtle and chronic inflammatory response. A substantial body of evidence has demonstrated the non-neuronal expression of dopamine, its receptors and of the machinery that governs synthesis, secretion and storage of dopamine across several immune cell types. This review aims to summarize current knowledge on the role and expression of dopamine in immune cells. One of the goals is to decipher the complex mechanisms through which these cell types respond to dopamine, in order to address the impact this has on neurodegenerative and psychiatric pathologies such as Parkinson’s disease. A further aim is to illustrate the gaps in our understanding of the physiological roles of dopamine to encourage more targeted research focused on understanding the consequences of aberrant dopamine production on immune regulation. These highlights may prompt scientists in the field to consider alternative functions of this important neurotransmitter when targeting neuroinflammatory/neurodegenerative pathologies.

Assessment of a Novel Surgical Technique for Acoustic Transmitter Insertion

This study compared three surgical techniques to implant acoustic transmitters in rainbow trout (Oncorhynchus mykiss): 1) acoustic transmitter insertion via a ventral incision closed with two sutures, 2) insertion via a ventral incision with no sutures, 3) insertion via a lateral incision with no sutures. A control group consisting of fish that were only anesthetized and handled was also included. Tag retention, wound healing, inflammation, growth, and survival were recorded over a 12-week period. Tag retention was significantly different among the treatments, at 100% in the unsutured ventral incision group, 89% in the lateral incision group, and 63% in the sutured ventral incision group. Surgical wounds in the unsutured treatment groups showed significantly less inflammation than the sutured treatment. Wound closure occurred significantly faster in the ventral incision groups compared to the lateral incision group. The results of this study show the utility of using unsutured surgical methods for implanting acoustic transmitters in rainbow trout.

A 2.4-GHz-Low-Power CMOS RF Transmitter for IEEE 802.15.4 Standard

This paper presents the experimental results of a low-power RF transmitter for 2.4-GHz-band IEEE 802.15.4 standard in 0.18-μm CMOS technology. In order to make an adaptive RF transmitter, several factors must be considered. The most important factors are performances, power consumption, output power, noise factor, and cost. The RF transmitter comprises a quadrature passive mixer, and a power amplifier. The proposed RF transmitter consumes only 10.8-mW under a supply voltage of 1.8-V.

Sampled-data modeling and dynamical effect of output-capacitor time-constant for valley voltage-mode controlled buck-boost converter

By analyzing the output voltage ripple of a buck-boost converter with large equivalent series resistance（ESR） of output capacitor, one valley voltage-mode controller for buck-boost converter is proposed. Considering the fact that the increasing and decreasing slopes of the inductor current are assumed to be constant during each switching cycle, an especial sampleddata model of valley voltage-mode controlled buck-boost converter is established. Based on this model, the dynamical effect of an output-capacitor time-constant on the valley voltage-mode controlled buck-boost converter is revealed and analyzed via the bifurcation diagrams, the movements of eigenvalues, the Lyapunov exponent spectra, the boundary equations,and the operating-state regions. It is found that with gradual reduction of output-capacitor time-constant, the buck-boost converter in continuous conduction mode（CCM） shows the evolutive dynamic behavior from period-1 to period-2, period-4, period-8, chaos, and invalid state. The stability boundary and the invalidated boundary are derived theoretically by stability analysis, where the stable state of valley voltage-mode controlled buck-boost converter can enter into an unstable state, and the converter can shift from the operation region to a forbidden region. These results verified by time-domain waveforms and phase portraits of both simulation and experiment indicate that the sampled-data model is correct and the time constant of the output capacitor is a critical factor for valley voltage-mode controlled buck-boost converter, which has a significant effect on the dynamics as well as control stability.

MISO-Type Voltage-Mode Universal Biquadratic Filter Using Single Universal Voltage Conveyor

A universal biquadratic filter using single universal voltage conveyor (UVC), two resistors and two capacitors is presented in this paper. The proposed structure has three inputs and one output and can realize all the five standard biquadratic filters: low-pass (LP), high-pass (HP), band-pass (BP), band-reject (BR) and all-pass (AP) from the same circuit configuration. The presented universal filter offers low active and passive sensitivities. SPICE (Version 16.5) simulation results using 0.18 μm TSMC technology have been included.

Novel DDS Based OFDM Transmitter Structure without IFFT and Interpolation Filter

The traditional orthogonal frequency divi-sion multiplexing(OFDM)transmitter is implemented by inverse fast Fourier transform(IFFT),up-sampling and low pass shaping filter(LPSF),which occupy a large number of hardware resources and have long la-tency.To further meet the 5G and future 6G commu-nication requirements,this paper proposes a novel di-rect digital synthesis(DDS)based OFDM transmitter structure that can replace these modules.Due to the strong parallelism of the system structure,it is very suitable for implementation on field programable gate array(FPGA)platform.After making two special sim-plifications to the primary structure,the refined struc-ture becomes very simple compared with the tradi-tional structures.Most attractively,the proposed struc-ture has the following three advantages that i)the data transformation from frequency domain to time domain has zero latency,ii)the transformation length does not need to be an integer power of 2 and iii)the struc-ture does not even need to use any multiplier,thus leading to low implementation complexity and high speed.Comparative experiments are carried out on Intel FPGA platform which show that our DDS based structure can save more than half of the resources com-pared with the traditional structures and can provide the same bit error rate(BER)performance under the condition without using any LPSF.

Optimization Design for the Sandwich Piezoelectric Transmitters in Acoustic Logging

An optimized transducer prototype with a sandwich structure vibrated longitudinally is proposed for a transmitter in acoustic logging, especially in acoustic logging while drilling, 5y taking account of drilling environments with high temperature and pressure, as well as strong collar drilling vibration during the drilling process. Aimed to improve the transmitting performance, numerical and experimental studies for the transducer optimization are conducted. The impact of location and length of the piezoelectric stack on resonance characteristics arid effective electromeehanical coupling coefficient is calculated and analyzed. Admittance and transmitting performance of the proposed transducer are measured in laboratory experiments, and the results are compared with simulated ones. It is shown that the newly proposed transducer has higher transmitting performance with lower resonance frequencies. This work provides theoretical and experimental bases for transducer designing and acoustic wave measurements in acoustic logging, especially in acoustic logging while drilling.

VDTA Based Electronically Tunable Voltage-Mode and Trans-Admittance Biquad Filter

In this paper, a biquad filter configuration based on two voltage differencing transconductance amplifiers (VDTAs) as newly active elements and only two capacitors as passive elements is proposed which can realize voltage-mode low pass (LP), band pass (BP), high pass (HP), band reject (BR) and all pass (AP) filtering responses using three voltage inputs. Simultaneously, the same configuration can also be used to obtain LP, BP and HP filtering responses in transadmittance-mode. The proposed biquad is capable of providing electronic control of quality factor independent of pole frequency through single transconductance parameter (biasing current). It also offers the advantage of low active and passive sensitivity. To support the theoretical analysis, the PSPICE simulation of the proposed circuit is done using 0.18 μm CMOS technology from TSMC.

Novel Surgical Technique for Acoustic Transmitter Insertion in Rainbow Trout Reduces the Need for Surgical Training

The implantation of acoustic transmitters into the peritoneal cavity of fish is typically performed by experienced surgeons. This study compared the effectiveness of an experienced and inexperienced surgeon performing two different types of transmitter insertion techniques on rainbow trout (Oncorhynchus mykiss). The methods used were either a traditional sutured ventral incision or a novel unsutured lateral incision. There was no significant difference in surgical duration, tag retention, or fish survival between the experienced and naïve surgeon. The time to complete surgical wound closure was not significantly different between the fish operated on by an experienced or naïve surgeon, and surgeon experience had no significant effect on the duration of inflammation. However, there were significant differences between the two surgical techniques, regardless of surgeon experience. The ventral incision with sutures method took approximately three times longer to complete than the lateral incision-only method. However, complete wound closure was significantly faster in the sutured ventral incision treatment compared to the unsutured lateral treatment. Post-surgery inflammation was over seven times longer in the fish with sutures compared to those only receiving a lateral incision. Tag retention was not significantly different between the two surgical methods. The results of this study indicate that the unsutured lateral surgical technique used in this experiment can be completed with minimal training and surgical experience in contrast to the standard technique requiring sutures. These results also provide additional support to the use of sutureless surgical techniques for acoustic transmitter implantation.

Voltage-Mode Universal Biquad Filter Employing Single Voltage Differencing Differential Input Buffered Amplifier

A new multi function voltage-mode universal biquadratic filter using single Voltage Differencing Differential Input Buffered Amplifier (VD-DIBA), two capacitors and one resistor is proposed. The proposed configuration has four inputs and one output and can realize all the five standard filters from the same circuit configuration. The presented biquad filter offers low active and passive sensitivities. The validity of proposed universal biquadratic filter has been verified by SPICE simulation using 0.35 μm MIETEC technology.

A 12-Bit 1-Gsample/s Nyquist Current-Steering DAC in 0.35 µm CMOS for Wireless Transmitter

The present work deals with 12-bit Nyquist current-steering CMOS digital-to-analog converter (DAC) which is an essential part in baseband section of wireless transmitter circuits. Using oversampling ratio (OSR) for the proposed DAC leads to avoid use of an active analog reconstruction filter. The optimum segmentation (75%) has been used to get the best DNL and reduce glitch energy. This segmentation ratio guarantees the monotonicity. Higher performance is achieved using a new 3-D thermometer decoding method which reduces the area, power consumption and the number of control signals of the digital section. Using two digital channels in parallel, helps reach 1-GSample/s frequency. Simulation results show that the spurious- free-dynamic-range (SFDR) in Nyquist rate is better than 64 dB for sampling frequency up to 1-GSample/s. The analog voltage supply is 3.3 V while the digital part of the chip operates with only 2.4 V. Total power consumption in Nyquist rate measurement is 144.9 mW. The chip has been processed in a standard 0.35 μm CMOS technology. Active area of chip is 1.37 mm2.

A New Voltage-Mode Universal Biquadratic Filter Using Single UVC

The paper presents a new universal biquadratic filter using single universal voltage conveyor (UVC), two resistors and two capacitors. The offered structure has three inputs and one output and can realise all the five basic biquadratic filters: high-pass (HP), low-pass (LP), band-reject (BR), band-pass (BP) and all-pass (AP) from the same circuit topology. The proposed universal filter also provides following advantageous features, not available simultaneously in any UVC based universal biquadratic filter so far: (i) low active and passive sensitivities, (ii) independent control of natural frequency (ω0) and bandwidth (BW) and (iii) no requirement of any component matching condition and inversion of input signal(s) (as needed in most of the earlier reported structures). The workability of proposed structure has been presented by SPICE (Version 16.5) simulation using 0.18 μm TSMC technology.

CMOS VDIBAs-Based Single-Resistance-Controlled Voltage-Mode Sinusoidal Oscillator

In this communication, a new single-resistance controlled sinusoidal oscillator (SRCO) has been presented. The presented SRCO uses two voltage differencing inverting buffered amplifiers (VDIBAs), one resistor and two capacitors in which one is grounded (GC) and the other one is floating (FC). The proposed structure offers the following advantageous features: 1) independent control of oscillation condition (OC) and oscillation frequency (OF);2) low passive and active sensitivities and 3) very good frequency stability. The non-ideal effects of the VDIBA on the proposed oscillator have also been investigated. The proposed SRCO has been tested for its robustness using Monte-Carlo simulations. The check of the validity of the presented SRCO has been established by SPICE simulations using 0.18 μm TSMC technology.

Dual DVCC Based Voltage-Mode Digitally Programmable Biquadratic Filter

The recent advances in IC technology have led to the trend of designing hybrid systems to benefit both analog and the digital domain. Among analog circuits, multifunctional filter along with multiphase oscillator constitutes a building block of critical importance. In this paper, a digitally reconfigurable multi-input-multi-output voltage mode multifunctional biquadratic filter has been presented. The circuit comprises of two differential voltage current conveyors (DVCCs), two grounded capacitors and two floating resistors. The digital controllability is incorporated using a current-summing network (CSN). Tunability of quality factor is achieved by the use of a 3-bit digital control word while keeping the resonant frequency constant. PSPICE simulations using TSMC 0.25 μm CMOS technology have been performed to validate the theoretically predicted results.

EFFECTS OF MOXIBUSTION ON THE IMMUNITY AND THE CENTRAL NERVOUS TRANSMITTERS IN MICE WITH YANG DEFICIENCY

In the present paper, the effects of moxibustion on the immune organs, on the multiplication reactivity of the splenic lymphocyte and the reactivity to the IL - 2, and on the transmitters in brain tissues of the mice with "yang deficiency" were studied. 30 mice were randomly divided into three groups: the normal group, the peng deficiency control group and the moxibustion treated group. Our study found out that in the mice of yang deficienly, the atrophy of the immunt organs was prevented, the reactivity of the splenocyte and the reactivity to IL - 2 were heightened, the amounts of the DA, NE and E in brain were increased significantly after moxibustion on the Point Shengshu. It can be held that moxibustion may protect the immune organs and regulate the immunity of the mouse with yang deficienly, and the effects may be contributed to the increase of the nervous transmitters in the brain.

INFLUENCE OF EA ON ELECTROCARDIOGRAM AND MONOAMINE TRANSMITTER AND c-Fos OF BRAIN STEM OF ACUTE MYOCARDIAL ISCHEMIA IN RATS

The present study aimed at the investigation of the changes of electrocardiogram (ECG) and monoamine transmitters in brainstem of rats with acute myocardial ischemia (AMl) with electroacupuncture (EA) at Neiguan (PC 6) and Jianshi (PC 5) treated by means of physiologic and histofluorescent and immunofluorescent methods. The results are as follows: 1. EA couId prevent ST segrnent and T wave from elevating during acute myocardial ischemia (P < 0. 05 ). 2. Monoamine-containing neurons with clear figure and bright fluoreasence, pre-and terminal axons were seen in Iocus coeruleus,lateral horn of splnal cord in two groups by the high specific sensitivity histofluorescence technique.The reaction of fluorescence was stronger in EA group than that in control one. The serotonin (5-HT) immunoreactive (ir) cells appeared in nucleus raphe (B 1, B 2). The 5-HT ir grains were more intense in EA group than that in control group. Tyrosine hydrotylase (TH) immunoreactive (ir) cell bodies were found within confines of catecholaminergic nuclei (A 1, A 2 ) of medulla. The immunofluorescence was weaker in EA group than that in control one. The results suggest that EA may regulate acute myocardial ischemia through brain stem.