Background: Neuroendocrine neoplasms are those that develop from a neuroendocrine cell. They most commonly affect the lungs, gastrointestinal tract, and pancreas, being rare conditions in the female genital tract. Whe...Background: Neuroendocrine neoplasms are those that develop from a neuroendocrine cell. They most commonly affect the lungs, gastrointestinal tract, and pancreas, being rare conditions in the female genital tract. When present, these neoplasms often manifest with nonspecific signs and symptoms such as pain, itching, swelling, single-focus lesions, bleeding, and enlargement of inguinal lymph nodes, in addition to the presence of progressively enlarging vulvar nodules. Consequently, the diagnostic investigation involves histopathological examination and confirmation through immunohistochemistry. Objective: To present a comprehensive understanding of this rarely studied pathology. The primary objective is to provide valuable insights that could aid in the future development of universally applicable treatment guidelines. Case Presentation: A 57-year-old female, with no prior comorbidities, menopause at 36, who presented with a left vulvar nodule accompanied by intense pain and swelling, later diagnosed with small cell neuroendocrine carcinoma in the vulva. Conclusion: This case report highlights the importance of enhancing our knowledge regarding small cell neuroendocrine carcinoma in the vulva, given its scarcity in medical literature. The information presented here underscores the need for standardized diagnostic and treatment approaches, paving the way for future consensus on managing this uncommon but challenging neoplasm.展开更多
A 25-year-old woman presented with a lump in the vulva associated with progressive difficulty in urination that had persisted for approximately half a year. A diagnosis of Bartholin＇s abscess had been made in another...A 25-year-old woman presented with a lump in the vulva associated with progressive difficulty in urination that had persisted for approximately half a year. A diagnosis of Bartholin＇s abscess had been made in another hospital. Incision revealed no pus and ultrasonography showed a solid lesion in the left vulva. Partial excision of the tumor was implemented and histopathology showed a small round cell tumor. There were no other significant findings in her present or past medical history. She was admitted to our hospital with vulvar cancer. On gynecological examination, a 7 cm × 6 cm finn, hard, painless mass was found in the left labium majora. The right labium was inflamed but painless.展开更多
文摘Background: Neuroendocrine neoplasms are those that develop from a neuroendocrine cell. They most commonly affect the lungs, gastrointestinal tract, and pancreas, being rare conditions in the female genital tract. When present, these neoplasms often manifest with nonspecific signs and symptoms such as pain, itching, swelling, single-focus lesions, bleeding, and enlargement of inguinal lymph nodes, in addition to the presence of progressively enlarging vulvar nodules. Consequently, the diagnostic investigation involves histopathological examination and confirmation through immunohistochemistry. Objective: To present a comprehensive understanding of this rarely studied pathology. The primary objective is to provide valuable insights that could aid in the future development of universally applicable treatment guidelines. Case Presentation: A 57-year-old female, with no prior comorbidities, menopause at 36, who presented with a left vulvar nodule accompanied by intense pain and swelling, later diagnosed with small cell neuroendocrine carcinoma in the vulva. Conclusion: This case report highlights the importance of enhancing our knowledge regarding small cell neuroendocrine carcinoma in the vulva, given its scarcity in medical literature. The information presented here underscores the need for standardized diagnostic and treatment approaches, paving the way for future consensus on managing this uncommon but challenging neoplasm.
文摘A 25-year-old woman presented with a lump in the vulva associated with progressive difficulty in urination that had persisted for approximately half a year. A diagnosis of Bartholin＇s abscess had been made in another hospital. Incision revealed no pus and ultrasonography showed a solid lesion in the left vulva. Partial excision of the tumor was implemented and histopathology showed a small round cell tumor. There were no other significant findings in her present or past medical history. She was admitted to our hospital with vulvar cancer. On gynecological examination, a 7 cm × 6 cm finn, hard, painless mass was found in the left labium majora. The right labium was inflamed but painless.
