Xingnao Kaiqiao needling method for acute ischemic stroke： a meta-analysis of safety and efficacy

OBJECTIVE： To evaluate the effectiveness and safety of the Xingnao Kaiqiao needling method for treating acute ischemic stroke.DATA SOURCES： We retrieved relevant randomized controlled trials involving Xingnao Kaiqiao acupuncture for treatment of acute ischemic stroke. The China National Knowledge Infrastructure, Weipu Information Resources System, Wanfang Medical Data System, Chinese Biomedical Literature Database, Cochrane Library, and Pub Med were searched from June 2006 to March 2016.DATA SELECTION： We analyzed randomized and semi-randomized clinical controlled trials that compared Xingnao Kaiqiao acupuncture with various control treatments, such as conventional drugs or other acupuncture therapies, for treatment of acute ischemic stroke. The quality of articles was evaluated according to the Cochrane Handbook for Systematic Reviews of Interventions（Version 5.1）, and the study was carried out using Cochrane system assessment methods. Rev Man 5.2 was used for the meta-analysis of the included studies.OUTCOME MEASURES： The mortality rate, disability rate, activities of daily living（Barthel Index）, and clinical efficacy were observed.RESULTS： Twelve studies met the inclusion criteria for this review. The meta-analysis showed that between Xingnao Kaiqiao acupuncture and the control treatment, Xingnao Kaiqiao acupuncture reduced the disability rate [risk ratio（RR） = 0.51, 95% confidence interval（CI） = 0.27-0.98, z = 2.03, P 〈 0.05], elevated the activities of daily living（weighted mean difference = 12.23, 95% CI： 3.66-20.08, z = 2.80, P 〈 0.005）, and had greater clinical efficacy（RR = 1.61, 95% CI： 1.23-2.09, z = 3.53, P 〈 0.0004）. However, there was no significant difference in mortality rate（RR = 0.61, 95% CI： 0.15-2.45, z = 0.70, P 〉 0.05）. CONCLUSION： The Xingnao Kaiqiao needling method is effective and safe for acute ischemic stroke. However, there was selective bias in this study, and the likelihood of measurement bias is high. Thus, more high-quality randomized controlled trials are needed to provide reliable evidence of the efficacy and safety of Xingnao Kaiqiao acupuncture in the treatment of acute ischemic stroke.

BRIEF INTRODUCTION TO THEORETICAL INTENTION OF "NEEDLING METHOD FOR TRANQUILLIZATION AND CALMING THE MIND" FOR TREATMENT OF INSOMNIA

A set of scientific theories and an effective acupuncture therapy for insomnia about ＂the needling method for tranquillization and calming the mind＂ are gradually formed through many years＇theoretical and clinical studies. In this paper, the theoretical intention about ＂the needling method for tranquillization and calming the mind＂ for treatment of insomnia are briefly introduced mainly from the cause of disease, pathogenesis, therapeutic method and characteristics of composition of a prescription, etc. in order to provide a new train of thoughts and a new method for working out scientific and standard prescriptions in the treatment of insomnia.

EIGHTY CASES of SOFT TISSUE INJURY TREATED WITH LOCAL CONTRALATERAL NEEDLING METHOD

Contralateral needling method is a common and effective one of acupuncture analgesicmethods.It is used to treat a local pain in the limbs and trunk with a short course of disease,pain and swelling will disappear or be relieved immediately for one or two treatments.Really,there isan effect of relieving pain as soon as the needle is inserted.When the local contralateral needlingmethod is used,the key to improving the effectiveness lies in determining the pain position and its correspondingpoint correctly,the more correct the pain position and its corresponding point are determined,the better the effectiveness will be.In this group,80 cases soft tissue injury were treatedwith local contralateral needling method,the cure rate was 82％,and the total effective rate was100％.

CLINICAL OBSERVATION ON TREATMENT OF PERIPHERAL FACIAL PARALYSIS WITH DIFFERENT NEEDLING METHODS

Purpose: To observe the clinical therapeutic effect of different needling methods in the treatment of peripheral facial paralysis. Methods: A total of 158 cases of peripheral facial palsy patients are randomly divided into treatment group (n=116 cases, who are treated by penetration needling method) and control group (n=42 cases, who are treated with traditional acupuncture method). In treatment group, main acupoint pairs for penetration needling are Yangbai (GB 14) -Yuyao (EX-HN 4), Tongziliao (GB 1) -Taiyang (EX-HN 5), Jiache (ST 6) -Dicang (ST 4) and Chengjiang (CV 24) -Jiachengjiang (EX-HN) on the affected side, and in control group, the main acupoints used are Yifeng (TE 17), Yangbai (GB 14), Sibai (ST 2), Dicang (ST 4), Jiache (ST 6), Jingming (BL 1) and Chengjiang (CV 24). The treatment is given once daily with 10 sessions being a therapeutic course. Results: After 3 courses of treatment, the cure rates of treatment group and control group are 81.8% and 66.7% separately, showing a significant difference between two groups (P<0.05). The total effective rates of treatment and control groups are 96.5% and 88.1% separately, presenting a significant difference between two groups (P<0.01). Conclusion: The therapeutic effect of penetration needling method is better than that of traditional acupuncture method.

Systematic review of long-term Xingnao Kaiqiao needling efficacy in ischemic stroke treatment

OBJeCTIve：To systematically evaluate the long-term effect and safety ofXingnao Kaiqiao nee-dling method in ischemic stroke treatment. DATA ReTRIevAL： We retrieved relevant random and semi-random controlled trials that used theXingnao Kaiqiao needling method to treat ischemic stroke compared with various control treatments such as conventional drugs or other acupuncture therapies. Searched databases included China National Knowledge Infrastructure, Weipu Information Resources System, Wanfang Medical Data System, Chinese Biomedical Literature Database, Cochrane Library, and PubMed, from May 2006 to July 2014. SeLeCTION CRITeRIA： Two authors independently conducted literature screening, quality evaluation, and data extraction. The quality of articles was evaluated according to the Cochrane Reviewers’ Handbook 5.1, and the study was carried out using Cochrane system assessment methods. RevMan 5.2 was used for meta-analysis of the included studies. MAIN OUTCOMe MeASUReS： Mortality rate, recurrence rate, and disability rate were observed. ReSULTS：Nine randomized and semi-randomized controlled trials treating 931 cases of ischemic stroke were included in this review. Meta-analysis results showed that there were no sig-niifcant differences in mortality reduction （risk ratio （RR） = 0.58, 95% conifdence interval （CI）： 0.17–1.93,Z = 0.89,P = 0.37） or recurrence rate （RR = 0.55, 95%CI： 0.18–1.70,Z = 1.04,P = 0.30） of ischemic stroke patients between theXingnao Kaiqiao needling and control treatment groups. However, theXingnao Kaiqiao needling method had a tendency towards higher efifcacy in mor-tality reduction and recurrence rates. TheXingnao Kaiqiao needling method was signiifcantly better than that of the control treatment in reducing disability rate （RR = 0.51, 95%CI： 0.27–0.98, Z = 2.03,P 〈 0.05）. CONCLUSION：TheXingnao Kaiqiao needling method has a better effect than control treatment in reducing disability rate. The long-term effect ofXingnao Kaiqiao needling against ischemic stroke is better than that of control treatment. However, the limitations of this study limit the strength of the conclusions. Randomized controlled trials with a strict, reasonable design, and multi-center, large-scale samples and follow-up are necessary to draw conclusions aboutXingnao Kaiqiao needling.

OBSERVATION ON THE EFFECT OF SHALLOW NEEDLING FOR TREATMENT OF PERIPHERAL FACIAL PARALYSIS IN 80 AFRICANS

This paper is a summary of 150 cases of facial paralysis in African black people treated with shallow needling and mild needling manipulation. After 3 courses of treatment, of the 80 cases in the shallow-needling group, 71 (88. 8% ) were cured, 5 (6. 3% ) had marked improvement, 3 (3. 7% ) had improvement and 1 (1. 2% ) failed; Of the 70 cases in traditional-needling group, 61 (87. 1 % ) were cured, 6 (8. 6% ) had evident improvement, 2 (2. 9% ) had improvement and 1 (1. 4 % ) had no striking change. Statistical analysis showed no significant difference between the two groups in the therapeutic effect (P >0. 5 ), indicating both the traditional needling method and shallow needling were effective in treatment of facial paralysis in black people. In addition, earlier treatment was very important in healing facial palsy; and the cure rate was higher in younger patients ard those with light severity.

Push vs pull method for endoscopic ultrasound-guided fine needle aspiration of pancreatic head lesions: Propensity score matching analysis

AIM To evaluate the efficacy of endoscopic ultrasoundguided fine needle aspiration(EUS-FNA) of pancreatic head cancer when pushing(push method) or pulling the echoendoscope(pull method).METHODS Overall, 566 pancreatic cancer patients had their first EUS-FNA between February 2001 and December 2017. Among them, 201 who underwent EUS-FNA for pancreatic head lesions were included in this study. EUS-FNA was performed by the push method in 85 patients, the pull method in 101 patients and both the push and pull methods in 15 patients. After propensity score matching(age, sex, tumor diameter, and FNA needle), 85 patients each were stratified into the push and pull groups. Patient characteristics and EUSFNA-related factors were compared between the two groups.RESULTS Patient characteristics were not significantly different between the two groups. The distance to lesion was significantly longer in the push group than in the pull group(13.9 ± 4.9 mm vs 7.0 ± 4.9 mm, P < 0.01). The push method was a significant factor influencing the distance to lesion(≥ median 10 mm)(P < 0.01). Additionally, tumor diameter ≥ 25 mm(OR = 1.91, 95%CI: 1.02-3.58, P = 0.043) and the push method(OR = 1.91, 95%CI: 1.03-3.55, P = 0.04) were significant factors contributing to the histological diagnosis of malignancy.CONCLUSION The pull method shortened the distance between the endoscope and the lesion and facilitated EUS-FNA of pancreatic head cancer. The push method contributed to the histological diagnosis of pancreatic head cancer using EUS-FNA specimens.

Observation of the Effectiveness of 56 Male Patients with Sexaul Disorder Treated by Needle－pricking Method

ＯｂｓｅｒｖａｔｉｏｎｏｆｔｈｅＥｆｆｅｃｔｉｖｅｎｅｓｓｏｆ５６ＭａｌｅＰａｔｉｅｎｔｓｗｉｔｈＳｅｘａｕｌＤｉｓｏｒｄｅｒＴｒｅａｔｅｄｂｙＮｅｅｄｌｅ－－ｐｒｉｃｋｉｎｇＭｅｔｈｏｄ￥ＺｅｎｇＹｕｅｐｉｎｇ（ＦａｎｇｃｕｉＤｉｓｔｒｉｃｔＰｅｏ...

Effects of cluster needling of scalp acupuncture on neurofilament protein 200 and signal transducer and activator of transcription 3 in rats with acute cerebral ischemia

Objective:Cluster needling at scalp acupoints has showed satisfying effects with acute cerebral ischemia in clinic whereas the mechanisms are not yet clear completely.This study investigated the influence of cluster needling at scalp acupoints on neurological function,as well as on neurofilament protein 200(NF200)and signal transducer and activator of transcription 3(STAT3)expression,in rats with acute cerebral ischemia.Methods:Fifty-four Sprague-Dawley rats were randomly assigned in equal numbers to the false operation(group F),model(group M),or cluster needling scalp acupuncture(group C)groups.Each group was divided into three subgroups,of six rats each,by acupuncture treatment time(24 h,7 days,and 14 days).The rat local cerebral ischemia model was prepared using a modified suture occlusion method.Group C rats were treated by cluster needling scalp acupuncture,while groups F and M did not receive acupuncture treatment.Neurological effects were evaluated using the Longa score.NF200 and STAT3 expression were measured by western blotting.Results:At 24 h,there were no statistical difference between group C and group M in nerve function(P>.05).On days 7 and 14,nerve function scores in group C were significantly lower than that in group M(respectively were P<.05 and P<.01).In addition,on days 14,expression of NF200 was significantly higher in group C compared with group M(P<.05).Compared with group M,STAT3 expression was also higher in group C on days 7 and 14,although these differences were not statistically significant(both P>.05).Conclusion:Cluster needling scalp acupuncture were efficient in improving nerve function scores in rats with cerebral ischemia,and promoting the recovery of motor function.These improvements were associated with increases in NF200 and STAT3 expression.

Effect of Wei’s triple nine needling therapy on flash visual evoked potentials in rats with traumatic optic neuropathy

Objective:To investigate the effect of Wei’s triple nine needling therapy on the N2-P2 wave of the flash visual evoked potential(FVEP)in rats of the of the transverse directional pulling model.Methods:Thirty-six Wistar rats were randomly grouped,nine were in normal control group without any treatment,and the remaining 27 were surgically modelled in the right eyes.Eighteen of these rats were randomly divided into a Wei’s triple nine needling therapy group and a model group of nine rats each after the TON model was made using the transverse quantitative retraction method.The other 9 rats were sham-operated,and only the optic nerve was exposed without retraction.On the next day of modelling,the Wei’s triple nine needling therapy group was treated with Wei’s triple nine needling therapy for 20 minutes/1 time/1 day for 14 days.The model group,sham-operated group and normal control group were not intervened.Wei's triple nine acupoints were represented as follows:1st link:"Jingming"(BL1)and"Chengqi"(ST1);2nd link:"Sizhukong"(SJ23)penetrating"Taiyang"(EX-HN5);and the third:"Fengchi"(GB 20)and"Taichong"(LV3).The FVEP of each group was observed on 1d,7d and 14d.The FVEP of each group was observed on 1d,7d and 14d.Results:Compared with the model group,the N2 wave latency and P2 wave latency were shortened in the Wei’s triple nine needling therapy on 1d(P<0.05,P<0.01);on 7d,their N2 wave latency was shortened(P<0.01)and the N2-P2 wave amplitude was increased compared with the model group(P<0.05);on 14d,their P2 wave latency was shortened(P<0.05)and the N2-P2 wave amplitude was increased.There was no statistical difference in N2 wave latency,P2 wave latency and N2-P2 wave amplitude in the sham-operated group on 1d,7d and 14d(P>0.05).The delayed N2 and P2 wave latencies in the model group did not improve from 1d to 14d(P>0.05)and the amplitude decreased throughout,showing a significant difference on 14d compared to 1d(P<0.05).In contrast,the N2 wave latency in Wei’s triple nine needling therapy group was not significantly different until 7d to 14d(P<0.05);its P2 wave latency,although significantly delayed from 1d to 7d(P<0.05),recovered on 14d and reached a level that was not statistically different from 1d and 7d(P>0.05).There was also no significant decrease in N2-P2 wave amplitude between 1d and 14d in Wei’s triple nine needling therapy group(P>0.05).Conclusion:In this experiment,the TON rat model was successfully established by the transverse quantitative retraction method,and the treatment of TON rats with Wei’s triple nine needling therapy reduced the P2 wave delay of the FVEP electrophysiological signal and increased the N2-P2 amplitude,which had a certain positive effect on the repair of optic nerve injury,probably related to its effect of improving the conduction function of the optic nerve and protecting the retinal ganglion cells that had not been degenerated and necrosed.

“假想层”在Needlee法膜系设计中的应用

Needle法是一种强大的膜系设计方法,它的突出特点是不依赖于初始膜系的给定,几乎对各种膜系设计目标都能给出比较令人满意的设计结果。但它的物理模型不够清楚,很难从直观上理解。通过在Needle法的推导过程中引入“假想层”的概念,使Needle法的整个推导过程清楚明了、容易理解,改进后的Needle法依然保持了它原来的各种优点。最后用两个设计实例说明了这种改进的有效性。

Needle-Tunneling法膜系自动设计

综述了Ｎｅｅｄｌｅ和Ｔｕｎｎｅｌｉｎｇ 法膜系自动设计的基本原理，举出它们的应用实例，并且指出一个优秀的光学膜系自动设计程序应该包括Ｎｅｅｄｌｅ 法、Ｔｕｎｎｅｌｉｎｇ 法和传统的优化方法。它们的结合和交叉使用，使我们有可能从单层膜开始设计任意光学性能的多层膜。

广义估计方程评估浮针法联合穴位埋线治疗不同分期膝骨关节炎的疗效

背景:穴位埋线法和浮针疗法是治疗膝骨关节炎的方法,但关于两种方法联合治疗的效果研究还鲜有报道。目的:运用广义估计方程探讨穴位埋线联合浮针法对不同分期膝骨关节炎的治疗效果。方法:选择2019年2月至2023年2月东莞市中医院收治的膝骨关节炎患者436例作为研究对象,随机分为2组,对照组(n=218)采用浮针法,观察组(n=218)采用穴位埋线法结合浮针疗法。以K-L分期方法为原则进行分期,其中对照组Ⅰ期57例,Ⅱ期62例,Ⅲ期49例,Ⅳ期50例;观察组Ⅰ期48例,Ⅱ期66例,Ⅲ期63例,Ⅳ期41例。比较两组患者治疗前后各指标水平及临床疗效;采用广义估计方程模型分析临床疗效的影响因素以及不同时点、不同方法、不同分期对治疗效果影响的交互效应。结果与结论:①观察组与对照组以及不同分期患者之间的基线资料均无显著差异(P>0.05),具有可比性;②两组患者经过治疗后Ⅰ期患者的治愈率最高,观察组总好转率显著高于对照组;组内比较,不同分期患者治愈率差异均有显著性意义(P<0.05);③两组患者经过治疗后各项指标均显著下降,对照组治疗4周后各指标不同分期患者相比差异均有显著性意义(P<0.05);观察组患者治疗2周后,各项指标不同分期患者相比差异即有显著性意义(P<0.05),且观察组治疗4周后各项指标均低于对照组(P<0.05),治疗效果优于对照组;④广义估计方程模型分析结果显示,创伤史、白细胞介素6水平、治疗方法、治疗时间和K-L分期均显著影响患者的临床疗效;⑤交互效应分析中,治疗2周两组患者中Ⅲ、Ⅳ期的目测类比评分有统计学意义(P<0.05);治疗4周时,两组患者中Ⅱ、Ⅲ、Ⅳ期患者的目测类比评分有统计学意义(P<0.05);⑥提示穴位埋线联合浮针法对不同分期膝骨关节炎的治疗效果优于单独浮针疗法,创伤史、白细胞介素6水平、治疗方法、治疗时间和K-L分期对患者的治疗效果有显著影响。

梅花针组穴叩刺法联合定点旋转复位法治疗神经根型颈椎病的临床研究

目的分析梅花针组穴叩刺法联合定点旋转复位法治疗神经根型颈椎病的效果及对患者疼痛、肌电图的影响。方法选取河南省洛阳正骨医院2021年4月至2024年4月103例神经根型颈椎病患者临床资料,按治疗方案分组,其中行旋转复位法治疗的34例为复位组,行梅花针组穴叩刺法治疗的34例为叩刺组,行旋转复位联合梅花针组穴叩刺治疗的35例为联合组。对比三组治疗效果、疾病相关评分[颈椎功能障碍指数(NDI)、颈椎病临床评价量表(CASCS)、视觉模拟评分法(VAS)评分]、肌电图指标、颈椎活动度。结果治疗4周后联合组治愈率为80.00%,高于复位组52.94%、叩刺组55.88%(P<0.05);治疗4周后联合组NDI、VAS评分低于复位组、叩刺组,CASCS评分高于复位组、叩刺组(P<0.05);治疗4周后联合组正中神经、腋神经的潜伏期均低于复位组、叩刺组,运动传导速度均高于复位组、叩刺组(P<0.05);治疗4周后颈椎侧屈、前屈、后伸活动度高于复位组、叩刺组(P<0.05)。结论神经根型颈椎病经梅花针组穴叩刺联合定点旋转复位治疗可提高治愈率,纠正颈椎功能,恢复颈椎活动度,改善神经传导功能,提高神经运动传导速度。

PREPARATION OF NANOMETER ZINC OXIDE BY EVAPORATION METHOD

Nanometer ZnO particles were synthesized by evaporating of zinc powders of averageparticle size of 370μm studied by XRD, TEM and electron diffraction. The particleswere formed by the oxidation of evaporated zinc vapor in the air. It was found that the particles range from 70 to 100nm in average particle size. The effect of experimental parameters was investigated, the increase of the air flow-rates reduced the average particle size, while increasing the evaporation temperature and the amount of metal charged increased the average particle size. TEM of the particles collected showed that the crystal habits of particles have a tetrapod-like of wurtzite structure consists of four needle crystals. It was found by electron diffraction that all particles were single crystal.

Investigation on the Micro-Discharge Characteristics of Dielectric Barrier Discharge in a Needle-Plate Geometry

In this study, a dielectric barrier discharge device with needle-plate electrodes was used to investigate the characteristics of the micro-discharge in argon at one atmospheric pressure by an optical method. The results show that there are two discharge modes in the dielectric barrier discharge, namely corona mode and filamentary mode. The corona discharge only occurs in the vicinity of the needle tip when the applied voltage is very low. However, the filamentary discharge mode can occur, and micro-discharge bridges the two electrodes when the applied voltage reaches a certain value. The extended area of micro-discharge on the dielectric plate becomes larger with the increase in applied voltage or decrease in gas pressure. The variance of the light emission waveforms is studied as a function of the applied voltage. Results show that very narrow discharge pulse only appears at the negative half cycle of the applied voltage in the corona discharge mode. However, broad hump （about several microseconds） can be discerned at both the negative half cycle and the positive half cycle for a high voltage in the filamentary mode. Furthermore, the inception voltage decreases and the width of the discharge hump increases with the increase in applied voltage. These experimental phenomena can be explained qualitatively by analyzing the discharge mechanism.

CLINICAL OBSERVATION ON 540 CASES OF GASTROPTOSIS TREATED WITH ELONGATED NEEDLE

Point penetration method by elongated needle and lifting manipulation were adopted totreat gastroptosis, getting marked effect. In this series of 540 cases, the cure rate was 40. 7 % and thetotal effective rate was 90. 7 %. There was a close relationship between the therapeutic effect and thedegree of gastroptosis, the cure rate of I° gastroptosis was 77. 6%, while that of Ⅲ° gastroptosis wasonly 11. 8 %. There was a very significant difference between them(P < 0. 001 )

THERAPY OF ELECTRIC OVOID NEEDLE-EXERCISE

In this paper, authors introduce a new treatment method called the therapy of electric ovoid needle combined with exercise. They used it to treat the soft tissue disorders and got satisfactory results.

关刺针法配合超声波治疗气滞血瘀型髌股关节疼痛综合征的临床观察

【目的】观察关刺针法配合超声波治疗气滞血瘀型髌股关节疼痛综合征的临床疗效。【方法】将86例气滞血瘀型髌股关节疼痛综合征患者随机分为观察组和对照组,每组各43例。对照组给予西医常规治疗联合功能锻炼,观察组在对照组治疗的基础上,给予关刺针法联合超声波治疗。连续治疗2周。治疗2周后,评价2组临床疗效,观察2组患者治疗前后膝关节疼痛视觉模拟量表(VAS)评分的变化情况,以及Kujala量表评分的情况。比较2组患者治疗前后患侧膝关节主动屈膝活动度(AROM)的变化情况。【结果】(1)治疗后,2组患者的VAS评分明显改善(P<0.05),且观察组在改善VAS评分水平方面明显优于对照组,差异有统计学意义(P<0.05)。(2)治疗后,2组患者的Kujala评分明显改善(P<0.05),且观察组在改善Kujala评分水平方面明显优于对照组,差异有统计学意义(P<0.05)。(3)治疗后,2组患者的AROM明显改善(P<0.05),且观察组在改善AROM水平方面明显优于对照组,差异有统计学意义(P<0.05)。(4)观察组总有效率为95.35%(41/43),对照组为81.40%(35/43)。观察组疗效优于对照组,差异有统计学意义(P<0.05)。【结论】关刺针法配合超声波治疗髌股关节疼痛综合征,能明显缓解患者的疼痛症状,促进膝关节功能的恢复,临床疗效显著。

基于经筋理论的膝骨关节炎患者“筋结点”超声解剖学特征分析与针刀治疗的疗效评价研究

目的:借助可视化肌骨超声深入剖析膝骨关节炎患者膝关节局部经筋病灶点的病理特征,并综合评价弓弦平衡针刀法与常规针刺法治疗膝骨关节炎的疗效差异,为今后针刀精准辨位定点及安全入路研究提供客观参考依据。方法:将120例膝骨关节炎患者随机分为针刀治疗组和针刺对照组,每组60例。针刀治疗组进行弓弦平衡针刀法治疗,每周2次;针刺对照组选取犊鼻、内膝眼、阳陵泉、梁丘、鹤顶,及局部阿是穴进行针刺,同时根据不同的证型进行配穴加减,每周3次。2组均以3周为1个疗程,治疗3个疗程。根据肌骨超声下“筋结点”的精确定位、层次解剖、回声特点深入剖析经筋病灶点的超声影像学特征,采用股直肌羽状角、肌纤维横断面积、西安大略和麦克马斯特大学骨关节炎指数(WOMAC)评分、白细胞介素-1β(IL-1β)、肿瘤坏死因子-α(TNF-α)综合评价2组疗效差异。结果:治疗后,2组患者WOMAC评分、股直肌羽状角、平均肌纤维厚度、弹性应变率、IL-1β、TNF-α水平,及膝关节疼痛程度、僵硬、日常活动能力方面较治疗前均显著改善(P <0.05);其中,针刀治疗组在提升股直肌羽状角、增加肌纤维厚度、降低弹性应变率、降低致炎致痛因子水平方面优于针刺对照组,差异有统计学意义(P <0.05);与正常膝关节超声解剖结构相比,患者膝关节各针刀松解点(筋结点)处呈现出不同程度回声增强,同时伴有滑膜增厚、增生、关节腔积液、滑囊积液等典型超声影像学特征。结论:肌骨超声能够精准呈现膝骨关节炎患者膝关节经筋病灶点的解剖位置、解剖层次等超声病变特征,证实弓弦平衡针刀法的安全性和有效性,为针刀医学的标准化、规范化研究提供重要参考依据。