Factors influencing willingness to participate in ophthalmic clinical trials and strategies for effective recruitment

AIM:To explore the factors influencing individuals’willingness to participate in ophthalmic clinical trials.METHODS:A questionnaire survey was conducted from January to April 2021 among patients and their family members at Zhongshan Ophthalmic Center,Sun Yat-sen University,in Guangzhou,China.The survey gathered data on respondents’willingness,demographic and socioeconomic profiles,as well as their reasons and concerns regarding engagement in clinical trials.RESULTS:Of the 1078 residents surveyed(mean age 31.2±13.1y;65.8%females)in Guangzhou,749(69.5%)expressed a willingness to participate in future ophthalmic clinical trials.Specific characteristics associated with greater willingness included a younger age,lower annual income,higher education,prior participation experience,previous ophthalmic treatment,and a better understanding of clinical trials.With the exception of age,these characteristics were significantly linked to a higher willingness.The primary barrier to participation,expressed by 64.8%of those willing and 54.4%of those unwilling,was“Uncertain efficacy”.In terms of motivations,the willing group ranked“Better therapeutic benefits”(35.0%),“Professional monitoring”(34.3%),and“Trust in healthcare professionals”(33.1%)as their top three reasons,whereas the unwilling participants indicated“Full comprehension of the protocol”(46.2%)as the key facilitator.CONCLUSION:This study reveals a substantial willingness to participate in ophthalmic clinical trials and demonstrates the predictive role of demographic and socioeconomic factors.Variations in motivators and concerns between willing and unwilling participants highlight the significance of tailored recruitment strategies.Importantly,the need for and trust in healthcare professionals stand out as powerful motivations,underscoring the importance of enhancing physician-patient relationships,adopting patient-centered communication approaches,and addressing individualized needs to improve accrual rates.

Will Online Car-Hailing Affect Consumers’ Decisions about Automobile Purchase?—An Empirical Study Based on Questionnaire Investigation

The online car-hailing industry, which provides the right of use, has a certain impact on the traditional automobile market, but there is no unified theory on whether it has a positive impact or a negative impact. Based on 362 consumer questionnaire data, this study builds a structural equation model to discuss the driving factors of residents’ choice of online car-hailing and whether the development of online car-hailing will have a certain substitution impact on the sales of private cars. From the perspective of consumers’ purchase intention, the research results show that consumers’ price consciousness, convenience consciousness, environmental protection consciousness and possession tendency will affect their choice of travel mode, and the use of online car-hailing is positively correlated with consumers’ willingness to replace private car ownership with online car-hailing.

A Study on the Factors Influencing Consumer Purchase Decision Under the Live-Streaming Sales Model

In recent years,with the rapid development and popularization of Internet information technology,many new media platforms have risen rapidly,and major e-commerce companies have begun to explore the mode of livestreaming.Especially during the COVID-19 pandemic,due to the lockdown,live-streaming has become an important means of economic development in many places.Owing to its remarkable characteristics of timeliness,entertainment,and interactivity,it has become the latest and trendiest sales mode of e-commerce channels,reflecting huge economic potential and commercial value.This article analyzes two models and their characteristics of live-streaming sales from a practical perspective.Based on this,it outlines consumer purchasing decisions and the factors that affect consumer purchasing decisions under the live-streaming sales model.Finally,it discusses targeted suggestions for using the live-streaming sales model to expand the consumer market,hoping to promote the healthy and steady development of the live-streaming sales industry.

Research on the Influence of Anchor Attributes on Consumers’Online Behaviors in Social E-Commerce Platforms:The Moderating Effect of Platform Contextual Factors

As e-commerce continues to mature,the advantages of live streaming within the industry have become increasingly apparent,offering significant growth opportunities.Social e-commerce platforms,which are user-centered,integrate social networks with e-commerce by leveraging social interactions to drive product sales and enhance the overall consumer shopping experience.This type of e-commerce fosters engagement and promotes products by merging online communities with shopping behavior,creating a more interactive and dynamic marketplace.It not only retains the traditional e-commerce trading and marketing functions but also adds a social dimension,making live stream anchors crucial figures connecting consumers with products.These anchors can attract consumers with their appearance and charm,and use their expertise on live streaming platforms to guide consumers by recommending live content.They can also interact with their audiences and potentially influence them to purchase the recommended goods.It is evident that the attributes of anchors in live streaming rooms significantly impact consumers’online behavior.Therefore,researching how platform contextual factors regulate consumers’online behavior is of great practical significance.This study employs multilevel regression analysis to support its hypotheses using data.The findings indicate that contextual factors of the platform significantly influence online behavior,enhancing the positive relationship between user attachment and online activities.

Living environment shaped residents’willingness to pay for ecosystem services in Yangtze River Middle Reaches Megalopolis,China

Profound understanding on the diversity of local residents’willingness to pay(WTP)for ecosystem services(ESs)may aid evaluation of policy impacts by uncovering trade-offs and synergies for achieving sustainable environmental resource management.However,the reasons for the spatial preference heterogeneity of WTP are still unclear.In this study,an extensive survey with 4,580 residents in the Yangtze River Middle Reaches Megalopolis(YRMRM),central China,was carried out to investigate the public’s WTP to maintain and improve ESs.We identified key influencing factors and explored how they shaped the preference heterogeneity in WTP by random forest model and surface fitting method.Our results showed that 81.4% of residents reported WTP for ESs greater than zero.Water supply,waste treatment,food supply and raw material supply were the preferred ESs for residents.Living environment factors(i.e.,extent of farmland,water and forest near the residence)were found as the key drivers of WTP.Proximity to farmland,water and forests resulted in high WTP values for a series of specific ESs.The reasons for the heterogeneity of WTP are(1)the difference in proximity to farmland,water and forest(i.e.,the contributor to ESs),(2)the divergence of local residents’preferences for ESs.This study disclosed the heterogeneity and causes of public preferences in YRMRM,which could help policy and decision makers to develop eco-compensation initiatives towards conservative and sustainable use of the environmental resources.

Analysis of Consumers' Willingness to Pay for Traceable Fresh Fruits in Shanghai City and Countermeasures

By the survey of consumers' behaviour of purchasing fresh fruits, this paper researches the group characteristics of people who consume traceable fresh fruits, and analyses the main factors influencing consumers' willingness to purchase. Based on this, corresponding proposals are put forward as follows: first, the government should not only focus on supervision and regulation over food security, but also strengthen the education of food security knowledge, publicity and promotion of traceable system; second, the government and related enterprise should particularly pay attention to the impact of consumers' individual characteristics on willingness to purchase and purchase behaviours, and work out feasible strategy of traceable food marketing, according to consumers' preferences, consumers' attention to health, consumers' attention to the healthy growth of children and other factors; finally, when implementing the system, the state and the government should take into full account the average income level of consumers, give full play to the effect of scale merit, and work out the reasonable price that can be accepted by most of consumers.

Consumer willingness to pay for plastic bags levy and willingness to accept eco-friendly alternatives in Botswana

Plastic bags, though commonly used for packaging of goods, are highly durable and non- biodegradable. Plastic bag litter serves as a negative environmental externality detrimental to animal health and natural beauty of the environment. In an effort to curtail the excessive use of plastic bags in Botswana, the government introduced a plastic levy targeted at consumers at retail points. This study uses primary data collected from 367 respondents randomly selected from six geospatially and purposively selected shopping malls to determine the consumers＇ willingness to pay （WTP） for continued plastic bag usage and their willingness to accept （WTA） to shift to eco-friendly alternatives. The results of the study revealed that open dumping and burning of plastic litter are more common in Maun than in Gaborone, It also showed that there is a significant relationship between the level of education and W＇FP. Further, there is a significant variation in income and education in respect to environmental awareness. The government should improve its efforts of sensitizing the public about the improper disposal of plastic bags.

A Study on The Factors Influencing the Facial Apparent Age of Chinese Cosmetic Consumers

To investigate the apparent age of Chinese cosmetic consumers and its influencing factors.The subjects’skin conditions in all dimensions were collected using professional instruments and clinical expert assessment,subjects’lifestyles,skin care and makeup habits were obtained through questionnaire.The apparent age of the subjects was obtained based on the visual perception of photos judged by observers and then averaged.The association between apparent age and skin characteristics,the association between the difference between apparent age and actual age and the subjects'lifestyle and its difference among cities were investigated.The results showed that apparent age had a high correlation with skin tone and severity of skin problems.The model of multiple regression analysis obtained a high resolution(R2=0.704).The use of skin care products may help to delay the apparent aging of the skin.The results of the study have some guiding significance for the development of anti-aging products and the evaluation of anti-aging efficacy and is informative for lifestyle choices to maintain youthfulness.

The Impact of Destination Image on Tourist Willingness to Revisit:A Case Study of Nanning Garden Expo

The researcher aims to examine the impact of destination image of Nanning Garden Expo on tourist willingness to revisit.In this study,Nanning Garden Expo,a famous comprehensive park in Nanning,Guangxi,is selected as the research object.Based on previous literature and theories,the author analyzes and explores the relationship between the destination image of Nanning Garden Expo and tourist willingness to revisit.The research tool is questionnaire and the sample size of the survey data is calculated by Cochrane formula,and the data collection volume is 385.The statistics used in the data analysis are descriptive statistics including frequency distribution,percentage,mean,standard deviation,and inferential statistic for testing hypothesis.The researcher applies multiple regression analysis models to examine which independent variables have strong or weak relationships with dependent variables.Hypothesis test indicates that destination image has a significant positive impact on tourist willingness to revisit.Based on the results of the empirical study,relevant suggestions are proposed for how to enhance tourist willingness to revisit for Nanning Garden Expo and promote the healthy and sustainable development of tourism.

Preference and Willingness of Consumers to Pay for Value-added Poultry Products in Niger Delta Region of Nigeria

There has been a steady growth in demand for convenience and ready-cooked food has influenced the interest of poultry processors in developing value-added chicken products that meet consumers＇ demand/choice. A conjoint analysis was done in this study on the survey of 975 chicken consumers in the Niger Delta Region of Nigeria, between March and September, 2014 to valuate consumers, preferences and willingness to pay （WTP） for various chicken attributed parts, production method, processing method, storage method, the presence of flavor and cooking method. The estimates of consumers, WTP premium prices for various mixtures of value-added characteristics were ascertained. The consumers preferred chicken products refrigerated, from chicken produced under free-range management, chicken breast, chicken product that was addictive and flavor free, which could be oven-heated or pan heated. One half of the entire respondents were willing to pay about 25% more for value-added chicken product over the price for conventional products. On the whole, a premium for value-added chicken products was more likely to be paid for by young consumers, consumers who patronized farmers＇ markets and preferred free-range or organic chicken products. WTP by consumers was negatively affected by price of products. The poultry industry could utilize combined knowledge of consumers＇ WTP for value-added chicken product price as a guide of develop innovative value-added chicken products.

Artificial Self-Recovery Opens up a New Journey of Autonomous Health of Mechanical Equipments

1.Introduction With the implementation of modern production strategies,such as“Industry 4.0”and“Made in China 2025,”the development of high-end mechanical equipment is gradually reaching a high degree of parameterization,digitalization,networking,and intelligence[1].High-end mechanical equipment no longer consists of traditional single devices,but is closely linked to the overall production process;that is,a variety of devices interact with each other and collectively form a complex system.However,faults can lead to production delays throughout the system and even seriously threaten the safety of workers[2].In addition,equipment operating in unmanned air or space vehicles(including space robots)cannot be repaired by humans if they break down[3].Until recently,the typical method of addressing machine faults was primarily the“fault cure”method,which involves manually shutting down,inspecting,and repairing the equipment to restore normal operation.Accordingly,the maintenance cycle of the traditional“fault cure”method is time-consuming,and the quality of the maintenance depends on the skills of the technician[4].

Impacts of information about COVID-19 on pig farmers'production willingness and behavior:Evidence from China

This paper examines the impacts of information about COVID-19 on pig farmers'production willingness by using endorsement experiments and follow-up surveys conducted in 2020 and 2021 in China.Our results show that,first,farmers were less willing to scale up production when they received information about COVID-19.The information in 2020 that the second wave of COVID-19 might occur without a vaccine reduced farmers'willingness to scale up by 13.4%,while the information in 2021 that COVID-19 might continue to spread despite the introduction of vaccine reduced farmers'willingness by 4.4%.Second,farmers whose production was affected by COVID-19 were considerably less willing to scale up,given the access to COVID-19 information.Third,farmers'production willingness can predict their actual production behavior.

Consumers’ Awareness of Genetically Modified Food and Their Willingness to Buy in Yanbian Prefecture

Having a clear understanding of consumers' awareness of genetically modified food and their willingness to buy, plays a very important role in formulating the regulatory policy of genetically modified food and regulating the market of genetically modified food. This paper takes the supermarket consumers as the study object. Through on-site questionnaire survey, we find that consumers' awareness of genetically modified food is not high in Yanbian Prefecture, and their willingness to buy is also low; the prices of genetically modified food, consumers' income, educational level and so on, are the main factors that affect the willingness to buy. Based on this, we put forth the relevant recommendations: increasing publicity efforts to safeguard consumers' right to know and choose; increasing supervision efforts to improve the existing regulatory system of genetically modified food; actively organizing forces to carry out the study on safety of genetically modified food.

Hong-Yang Wang:devoted to discovery—a female scientist who is willing to lead

1.Introducing Professor Wang ProfessorHong-YangWangwas admitted to the MedicalDepartment,Second Military Medical University,in 1973.After graduation,she worked as a physician for the Department of Gastroenterology,Changzheng Hospital,Shanghai,while earning herMaster's inGastrointestinal Immunology(awarded in 1984).As a chief physician,ProfessorWang was encouraged by academician Mengchao Wu to pursue a Ph.D.in clinical biochemistry at theMedical School of theUniversity of Ulm,Germany,in 1989.

Over Voltage Fault due to Disconnection of Consumer’s Transformer Neutral Wire

Practically,the load currents in three phases are asymmetric in the power system.It means that the impedances are different in all three phases.If the consumer’s transformer neutral cut off and/or was disconnected from the neutral of power supply source,then there will be some trouble and failure occurred.The current in the neutral wire drops down to zero when the neutral wire is cut off and the phase currents of all three-phase equal to each other since there was no return wire.The currents are equal but the voltages at the phase consumers are different.Especially for residential single-phase consumers,the voltage at the consumers of the phase varies differently for three phase systems when the neutral wire was disconnected at consumer side and even the voltage at the consumers one or two of those three phases becomes over nominal voltage or reaches nearly line voltage.In this case,the electronic appliances in that phase will be fed by high voltage than the rated value and they can be broken down.In the power system of UB(Ulaanbaatar)city,there are some occasional such kind of failures every year.Obviously,many electronic appliances were broken down due to high voltage and the electricity utility companies respond for service charge of damaged parts.

Tourists’Willingness to Pay for Recreation Services in Nyerere National Park,Tanzania:Are We Overvaluing or Undervaluing Our Nature Recreation Resources?

This study estimated tourists’Willingness to Pay(WTP)per day for recreation services in Nyerere National Park(NNP)and compared these values with daily travel costs that are incurred by tourists to visit NNP in order to inform whether recreation resources in the park are overvalued or undervalued.The study revealed that tourists’WTP per day for recreation services was estimated at$237.4 and$1521 for resident and non-resident tourists,respectively.The estimated tourists’WTP values exceed the daily travel costs currently incurred by tourists,which are$201.04 and$1517.97 for resident and non-resident tourists,respectively.This indicates that tourists are willing to spend more to enjoy recreation services in NNP,which signifies that recreation resources in NNP are slightly undervalued.In addi­tion,the findings disclosed that the largest share of tourist daily travel expenses is allocated to transportation services,and very little is paid to the park as a conservation fee.It was revealed that out of the daily travel expenses incurred by non-resident and resident tourists,only 4.62%and 2.23%are respectively paid directly to NNP as conservation fees.This study considers that allocation is not very fair;thus,NNP,in collaboration with TANAPA,needs to adjust the current entrance or conservation fee and reduce the transportation costs charged by tourist companies.The travel costs incurred by tourists,age,education,monthly income,site visited,substitute site,and quality of park were identified as significant factors in influencing tourists’WTP for recreation services in NNP.Thus,policies oriented to reduce tour­ists’transportation costs and improve the quality of national parks would attract more tourists to NNP.

Discovering Niche Market： Consumer Preferences and Willingness to Pay for Organic Pork

With the concern for environmental quality and food safety, organic food products are becoming more important in the global market. In recent years the organic food industry has been expanding and sales of organic products have been increasing. Abundant studies have been done focusing on organic fruits and vegetables which focused on the shortage of organic live stocks. In this paper we focus our attention on organic pork products. Using a sample of 400 Thais consumers, this study proposes the contingent valuation （CV） technique to measure the willingness of individuals to pay a price premium for organic pork in Thailand. In order to obtain the mean ＂willingness to pay＂ （WTP）, a bivariate probit model was applied to provide information about the crucial variables that affect the WTP. The study revealed that variables that better approximate WTP are based on the lifestyle and knowledge about organic foods rather than the usual socioeconomic factors. The mean WTP on the premium price for organic pork is approximately 34.30 Bath per kg. In order to access the market potential this study shows that the suitable attributes of organic pork which is consistent with consumer preferences are composed of modernized and environmental packaging with special product details. Marketing this product to the buyer it should be set at a reasonable price. Stimulating the market should be done by doing sales promotion and public relations on a regularly basis. In addition, organic pork should be available in any places and convenient for customers to buy.

Impact of Sharing Marketing on Marketing Willingness of Employees in Internet Decoration Industry

With the development of information technology,sharing marketing,as an innovative marketing method,plays an important role in promoting the marketing willingness and enthusiasm of employees in the Internet decoration industry.Based on the data obtained from the ques-tionnaire survey,this paper makes an empirical analysis of the impact of the economic value,social value,perceived ease of use,perceived convenience,enabling conditions and subjective norms of sharing marketing on the marketing willingness of employees in the Internet decoration industry.The results showed that the questionnaire had good internal consistency and construct validity.Through empirical analysis,it can be found that the economic value,social value,perceived ease of use,perceived convenience,enabling conditions and subjective norms of sharing marketing have a significant positive impact on employees'marketing willingness.

Impact mechanism of perception on the protection intention of tourist heritage sites:Taking the Hangzhou section of the Grand Canal as an example

Heritage tourism is a hot research topic in the academic field,and most scholars focus on the development model of heritage tourism and heritage conservation theory and methods,but less on the heritage tourists themselves.Based on the theory of planned behavior,the study introduces the variable of“perception”,and takes the Hangzhou section of the Grand Canal as a case study,and investigates tourists through literature,fieldwork and questionnaires.The study constructs a“perception-subjective norm-willingness to protect”model to explore the influence of tourists’“perception”and“subjective norm”on“willingness to protect”.The study found that:first,heritage tourists’perceptions significantly affect attitudes,subjective norms,perceptual behavior control and willingness to conserve.Second,tourists’attitudes,subjective norms and perceptual behavior control significantly affect their willingness to conserve.Third,heritage tourists’economic perceptions,social perceptions and emotional perceptions can affect willingness to conserve.The study provides references for relevant governments and tourism enterprises to conserve and develop the Grand Canal section.

Omni-Channel Retailing and Firm Performance from a Customer Lifetime Value Perspective

In the digital era,retailers are keen to find out whether omni-channel retailing helps improve long-term firm performance.In this paper,we employ machine learning techniques on a large consumption data set in order to measure customer lifetime value(CLV)as the basis for determining long-term firm performance,and we provide an empirical analysis of the relationship between omni-channel retailing and CLV.The results suggest that omni-channel retailing may effectively enhance CLV.Further analysis reveals that this process is influenced by heterogeneous consumer requirements and that significant differences exist in the extent to which the omni-channel transition may influence CLV depending on consumer preferences for diversity of commodities,sensitivity to the cost of contract performance,and sensitivity to warehousing costs.Hence,retailers should provide consumers with a complete portfolio of goods and services based on target consumers’heterogeneous requirements in order to increase omni-channel efficiency.