OptoGPT: A foundation model for inverse design in optical multilayer thin film structures

Optical multilayer thin film structures have been widely used in numerous photonic applications.However,existing inverse design methods have many drawbacks because they either fail to quickly adapt to different design targets,or are difficult to suit for different types of structures,e.g.,designing for different materials at each layer.These methods also cannot accommodate versatile design situations under different angles and polarizations.In addition,how to benefit practical fabrications and manufacturing has not been extensively considered yet.In this work,we introduce OptoGPT(Opto Generative Pretrained Transformer),a decoder-only transformer,to solve all these drawbacks and issues simultaneously.

Emerging structures and dynamic mechanisms ofγ-secretase for Alzheimer’s disease

γ-Secretase,called“the proteasome of the membrane,”is a membrane-embedded protease complex that cleaves 150+peptide substrates with central roles in biology and medicine,including amyloid precursor protein and the Notch family of cell-surface receptors.Mutations inγ-secretase and amyloid precursor protein lead to early-onset familial Alzheimer’s disease.γ-Secretase has thus served as a critical drug target for treating familial Alzheimer’s disease and the more common late-onset Alzheimer’s disease as well.However,critical gaps remain in understanding the mechanisms of processive proteolysis of substrates,the effects of familial Alzheimer’s disease mutations,and allosteric modulation of substrate cleavage byγ-secretase.In this review,we focus on recent studies of structural dynamic mechanisms ofγ-secretase.Different mechanisms,including the“Fit-Stay-Trim,”“Sliding-Unwinding,”and“Tilting-Unwinding,”have been proposed for substrate proteolysis of amyloid precursor protein byγ-secretase based on all-atom molecular dynamics simulations.While an incorrect registry of the Notch1 substrate was identified in the cryo-electron microscopy structure of Notch1-boundγ-secretase,molecular dynamics simulations on a resolved model of Notch1-boundγ-secretase that was reconstructed using the amyloid precursor protein-boundγ-secretase as a template successfully capturedγ-secretase activation for proper cleavages of both wildtype and mutant Notch,being consistent with biochemical experimental findings.The approach could be potentially applied to decipher the processing mechanisms of various substrates byγ-secretase.In addition,controversy over the effects of familial Alzheimer’s disease mutations,particularly the issue of whether they stabilize or destabilizeγ-secretase-substrate complexes,is discussed.Finally,an outlook is provided for future studies ofγ-secretase,including pathways of substrate binding and product release,effects of modulators on familial Alzheimer’s disease mutations of theγ-secretase-substrate complexes.Comprehensive understanding of the functional mechanisms ofγ-secretase will greatly facilitate the rational design of effective drug molecules for treating familial Alzheimer’s disease and perhaps Alzheimer’s disease in general.

Web Layout Design of Large Cavity Structures Based on Topology Optimization

Large cavity structures are widely employed in aerospace engineering, such as thin-walled cylinders, blades andwings. Enhancing performance of aerial vehicles while reducing manufacturing costs and fuel consumptionhas become a focal point for contemporary researchers. Therefore, this paper aims to investigate the topologyoptimization of large cavity structures as a means to enhance their performance, safety, and efficiency. By usingthe variable density method, lightweight design is achieved without compromising structural strength. Theoptimization model considers both concentrated and distributed loads, and utilizes techniques like sensitivityfiltering and projection to obtain a robust optimized configuration. The mechanical properties are checked bycomparing the stress distribution and displacement of the unoptimized and optimized structures under the sameload. The results confirm that the optimized structures exhibit improved mechanical properties, thus offering keyinsights for engineering lightweight, high-strength large cavity structures.

A Hybrid Level Set Optimization Design Method of Functionally Graded Cellular Structures Considering Connectivity

With the continuous advancement in topology optimization and additive manufacturing(AM)technology,the capability to fabricate functionally graded materials and intricate cellular structures with spatially varying microstructures has grown significantly.However,a critical challenge is encountered in the design of these structures–the absence of robust interface connections between adjacent microstructures,potentially resulting in diminished efficiency or macroscopic failure.A Hybrid Level Set Method(HLSM)is proposed,specifically designed to enhance connectivity among non-uniform microstructures,contributing to the design of functionally graded cellular structures.The HLSM introduces a pioneering algorithm for effectively blending heterogeneous microstructure interfaces.Initially,an interpolation algorithm is presented to construct transition microstructures seamlessly connected on both sides.Subsequently,the algorithm enables the morphing of non-uniform unit cells to seamlessly adapt to interconnected adjacent microstructures.The method,seamlessly integrated into a multi-scale topology optimization framework using the level set method,exhibits its efficacy through numerical examples,showcasing its prowess in optimizing 2D and 3D functionally graded materials(FGM)and multi-scale topology optimization.In essence,the pressing issue of interface connections in complex structure design is not only addressed but also a robust methodology is introduced,substantiated by numerical evidence,advancing optimization capabilities in the realm of functionally graded materials and cellular structures.

Cost-optimization based target reliabilities for design of structures exposed to fire

Adequacy of structural fire design in uncommon structures is conceptually ensured through cost-benefit analysis where the future costs are balanced against the benefits of safety investment.Cost-benefit analyses,however,are complicated and computationally challenging,and hence impractical for application to individual projects.To address this issue,design guidance proposes target reliability indices for normal design conditions,but no target reliability indices are defined for structural fire design.We revisit the background of the cost-optimization based approach underlying normal design target reliability indices then we extend this approach for the case of fire design of structures.We also propose a modified objective function for cost-optimization which simplifies the evaluation of target reliability indices and reduces the number of assumptions.The optimum safety level is expressed as a function of a new dimensionless variable named“Damage-to-investment indicator”(DII).The cost optimization approach is validated for the target reliability indices for normal design condition.The method is then applied for evaluating DII and the associated optimum reliability indices for fire-exposed structures.Two case studies are presented:(i)a one-way loaded reinforced concrete slab and(ii)a steel column under axial loading.This study thus provides a framework for deriving optimum(target)reliability index for structural fire design which can support the development of rational provisions in codes and standards.

The MDOF equivalent linear system and its applications in seismic analysis and design of framed structures

This paper reviews the applications of the multi degree-of-freedom(MDOF)equivalent linear system in seismic analysis and design of planar steel and reinforced concrete framed structures.An equivalent MDOF linear structure,analogous to the original MDOF nonlinear structure,is constructed,which has the same mass and elastic stiffness as the original structure and modal damping ratios that account for the effects of geometrical and material nonlinearities.The equivalence implies a balance between the viscous damping work of the equivalent linear structure and that of the nonlinearities in the original nonlinear structure.This work balance is established with the aid of a transfer function in the frequency domain.Thus,equivalent modal damping ratios can be explicitly determined in terms of the period and deformation levels of the structure as well as the soil types.Use of these equivalent modal damping ratios can help address a variety of seismic analysis and design problems associated with planar steel and reinforced concrete framed structures in a rational and accurate manner.These include force-based seismic design with the aid of acceleration response spectra characterized by high amounts of damping,improved direct displacement-based seismic design and the development of advanced seismic intensity measures.The equivalent modal damping ratios are also utilized in the context of linear modal analysis for the definition and construction of the MDOF response spectrum.Furthermore,the equivalent modal damping ratios are employed in a seismic retrofit method for steel-framed structures with viscous dampers.Finally,it is demonstrated that modal behavior(or strength reduction)factors can be easily constructed based on these modal damping ratios for a more rational and accurate force-based seismic design,including the determination of inelastic displacement profiles.

DYNAMIC RESPONSE OPTIMIZATION DESIGN FOR ENGINEERING STRUCTURES BASED ON RELIABILITY

In many practical structures, physical parameters of material and applied loads have random property.To optimize this kind of structures,an optimum mathematical model was built.This model has reliability constraints on dynamic stress and displacement and upper & lower limits of the design variables. The numerical characteristic of dynamic response and sensitivity of dynamic response based on probability of structure were deduced respectively. By equivalent disposing, the reliability constraints were changed into conventional forms. The SUMT method was used in the optimization process.Two examples illustrate the correctness and practicability of the optimum model and solving approach.

The Optimal Design of TMD for Offshore Structures

This paper presents the optimal design procedure of Tuned Mass Damper (TMD) for reducing vibration of an actual steel jacket offshore platform excited by random wave loading. In this study, a frequency domain is taken. The force on the structure is determined by use of the linearized Morison equation for an input Power Spectral Density (PSD) of wave elevation. The sensitivity of optimum values of TMD to characteristic parameters of random wave spectrum is analyzed. An optimized TMD design for the modeled platform is given based on design conditions and the findings of the study.

An improved pseudo-static method for seismic resistant design of underground structures

This paper describes a commonly used pseudo-static method in seismic resistant design of the cross section of underground structures. Based on dynamic theory and the vibration characteristics of underground structures, the sources of errors when using this method are analyzed. The traditional seismic motion loading approach is replaced by a method in which a one-dimensional soil layer response stress is differentiated and then converted into seismic live loads. To validate the improved method, a comparison of analytical results is conducted for internal forces under earthquake shaking of a typical shallow embedded box-shaped subway station structure using four methods： the response displacement method, finite element response acceleration method, the finite element dynamic analysis method and the improved pseudo-static calculation method. It is shown that the improved finite element pseudo-static method proposed in this paper provides an effective tool for the seismic design of underground structures. The evaluation yields results close to those obtained by the finite element dynamic analysis method, and shows that the improved finite element pseudo-static method provides a higher degree of precision.

Novel Surface Design of Deployable Reflector Antenna Based on Polar Scissor Structures

Space-deployable mechanisms can be used as supporting structures for large-diameter antennas in space engineering.This study proposes a novel method for constructing the surface design of space reflector antennas based on polar scissor units.The concurrency and deployability equations of the space scissor unit with definite surface constraints are derived using the rod and vector methods.Constraint equations of the spatial transformation for space n-edge polar scissor units are summarized.A new closed-loop deployable structure,called the polar scissor deployable antenna(PSDA),is designed by combining planar polar scissor units with spatial polar scissor units.The overconstrained problem is solved by releasing the curve constraint that locates at the end-point of the planar scissor mechanism.Kinematics simulation and error analysis are performed.The results show that the PSDA can effectively fit the paraboloid of revolution.Finally,deployment experiments verify the validity and feasibility of the proposed design method,which provides a new idea for the construction of large space-reflector antennas.

An origami shield with supporting frame structures optimized by a feature-driven topology optimization method

In this paper,the design,manufacture and testing of an origami protective shield with a supporting frame structure are presented.It consists of an origami shield surface and a deployable supporting frame structure that needs to be portable and sufficiently stiff.First,for the design of the shield surface,a threestage origami crease pattern is developed to reduce the shield size in the folded state.The shield surface consists of several stiff modular panels and layered with flexible fabric.The modular panels are made of a multi-layer composite where a ceramic layer is made of small pieces to improve durability as those small pieces enable restriction of crack propagation.Then,the supporting frame structure is designed as a chain-of-bars structure in order to fold into a highly compact state as a bundle of bars and deploy in sequence.Thus,a feature-driven topology structural optimization method preserving component sequence is developed where the inter-dependence of sub-structures is taken into account.A bar with semi-circular ends is used as a basic design feature.The positions of the bar’s end points are treated as design variables and the width of the bars is kept constant.Then,a constraint on the total length of the chain of bars is introduced.Finally,the modular panels made of multi-layer composite and the full-scale prototype of the origami shield are fabricated and tested to verify the bullet-proof performance.

Crashworthiness Design and Multi-Objective Optimization for Bio-Inspired Hierarchical Thin-Walled Structures

Thin-walled structures have been used in many fields due to their superior mechanical properties.In this paper,two types of hierarchical multi-cell tubes,inspired by the self-similarity of Pinus sylvestris,are proposed to enhance structural energy absorption performance.The finite element models of the hierarchical structures are established to validate the crashworthiness performance under axial dynamic load.The theoreticalmodel of themean crushing force is also derived based on the simplified super folded element theory.The finite element results demonstrate that the energy absorption characteristics and deformation mode of the bionic hierarchical thin-walled tubes are further improved with the increase of hierarchical sub-structures.It can be also obtained that the energy absorption performance of corner self-similar tubes is better than edge self-similar tubes.Furthermore,multiobjective optimization of the hierarchical tubes is constructed by employing the response surface method and genetic algorithm,and the corresponding Pareto front diagram is obtained.This research provides a new idea for the crashworthiness design of thin-walled structures.

Bioinspired directional structures for inhibiting wetting on super-melt-philic surfaces above 1200°C

Over the past two decades,superhydrophobic surfaces that are easily created have aroused considerable attention for their superior performances in various applications at room temperature.Nowadays,there is a growing demand in special fields for the development of surfaces that can resist wetting by high-temperature molten droplets(>1200°C)using facile design and fabrication strategies.Herein,bioinspired directional structures(BDSs)were prepared on Y2O3-stabilized ZrO2(YSZ)surfaces using femtosecond laser ablation.Benefiting from the anisotropic energy barriers,the BDSs featured with no additional modifiers showed a remarkable increase from 9.2°to 60°in the contact angle of CaO–MgO–Al2O3–SiO2(CMAS)melt and a 70.1%reduction in the spreading area of CMAS at 1250°C,compared with polished super-CMAS-melt-philic YSZ surfaces.Moreover,the BDSs demonstrated exceptional wetting inhibition even at 1400°C,with an increase from 3.3°to 31.3°in contact angle and a 67.9%decrease in spreading area.This work provides valuable insight and a facile preparation strategy for effectively inhibiting the wetting of molten droplets on super-melt-philic surfaces at extremely high temperatures.

Optimal design and effectiveness evaluation for inerter-based devices on mitigating seismic responses of base isolated structures

The optimal design and effectiveness of three control systems,tuned viscous mass damper(TVMD),tuned inerter damper(TID)and tuned mass damper(TMD),on mitigating the seismic responses of base isolated structures,were systematically studied.First,the seismic responses of the base isolated structure with each control system under white noise excitation were obtained.Then,the structural parameter optimizations of the TVMD,TID and TMD were conducted by using three different objectives.The results show that the three control systems were all effective in minimizing the root mean square value of seismic responses,including the base shear of the BIS,the absolute acceleration of structural SDOF,and the relative displacement between the base isolation floor and the foundation.Finally,considering the superstructure as a structural MDOF,a series of time history analyses were performed to investigate the effectiveness and activation sensitivity of the three control systems under far field and near fault seismic excitations.The results show that the effectiveness of TID and TMD with optimized parameters on mitigating the seismic responses of base isolated structures increased as the mass ratio increases,and the effectiveness of TID was always better than TMD with the same mass ratio.The TVMD with a lower mass ratio was more efficient in reducing the seismic response than the TID and TMD.Furthermore,the TVMD,when compared with TMD and TID,had better activation sensitivity and a smaller stroke.

Vibration Control of the Rail Grinding Vehicle with Abrasive Belt Based on Structural Optimization and Lightweight Design

As a new grinding and maintenance technology,rail belt grinding shows significant advantages in many applications The dynamic characteristics of the rail belt grinding vehicle largely determines its grinding performance and service life.In order to explore the vibration control method of the rail grinding vehicle with abrasive belt,the vibration response changes in structural optimization and lightweight design are respectively analyzed through transient response and random vibration simulations in this paper.Firstly,the transient response simulation analysis of the rail grinding vehicle with abrasive belt is carried out under operating conditions and non-operating conditions.Secondly,the vibration control of the grinding vehicle is implemented by setting vibration isolation elements,optimizing the structure,and increasing damping.Thirdly,in order to further explore the dynamic characteristics of the rail grinding vehicle,the random vibration simulation analysis of the grinding vehicle is carried out under the condition of the horizontal irregularity of the American AAR6 track.Finally,by replacing the Q235 steel frame material with 7075 aluminum alloy and LA43M magnesium alloy,both vibration control and lightweight design can be achieved simultaneously.The results of transient dynamic response analysis show that the acceleration of most positions in the two working conditions exceeds the standard value in GB/T 17426-1998 standard.By optimizing the structure of the grinding vehicle in three ways,the average vibration acceleration of the whole car is reduced by about 55.1%from 15.6 m/s^(2) to 7.0 m/s^(2).The results of random vibration analysis show that the grinding vehicle with Q235 steel frame does not meet the safety conditions of 3σ.By changing frame material,the maximum vibration stress of the vehicle can be reduced from 240.7 MPa to 160.0 MPa and the weight of the grinding vehicle is reduced by about 21.7%from 1500 kg to 1175 kg.The modal analysis results indicate that the vibration control of the grinding vehicle can be realized by optimizing the structure and replacing the materials with lower stiffness under the premise of ensuring the overall strength.The study provides the basis for the development of lightweight,diversified and efficient rail grinding equipment.

Redundancy Measure and Its Application to the Design and Maintenance of Marine Structures

This paper is a survey of the state-of-the-art knowledge in structural redundancy measure and its application. The existing deterministic and probabilistic measures of structural redundancy are summarized. Emphasis is given to the discussion of their advantages and limitations. The application bf damage tolerance concept in the design and maintenance of marine structures is also reviewed. Some most critical problems in structural redundancy are proposed for future research.

Layout design and application of 4D-printing bio-inspired structures with programmable actuators

Four-dimensional(4D)printing is an advanced form of three-dimensional(3D)printing with controllable and programmable shape transformation over time.Actuators are used as a controlling factor with multi-stage shape recovery,with emerging opportunities to customize the mechanical properties of bio-inspired structures.The print pattern of shape memory polymer(SMP)fbers strongly afects the achievable resolution,and consequently infuences several other physical and mechanical properties of fabricated actuators.However,the deformations of bio-inspired structures due to actuator layout are more complex because of the presence of the coupling of multi-directional strain.In this study,the initial structure was designed from closed-shell behavior and divided into a general unit and actuator unit,the latter responsible for driving the transformation.Mutual stress confrontation between the actuator and the general unit was considered in the layout thermodynamic model,in order to eliminate the transformation produced by the uncontrolled shape memory behavior of the general unit.Three critical and efective strategies for the layout design of actuators were proposed and then applied to achieve the desired accurate deformation of 3D-printed bilayer structures.Finally,the proposed approach was validated and adopted for fabricating a complex shell-like gripper structure.

Research and development of a digital design system for hull structures

Methods used for digital ship design were studied and formed the basis of a proposed frame model suitable for ship construction modeling. Based on 3-D modeling software, a digital design system for hull structures was developed. Basic software systems for modeling, modifying, and assembly simulation were developed. The system has good compatibility, and models created by it can be saved in different 3-D file formats, and 2D engineering drawings can be output directly. The model can be modified dynamically, overcoming the necessity of repeated modifications during hull structural design. Through operations such as model construction, intervention inspection, and collision detection, problems can be identified and modified during the hull structural design stage. Technologies for centralized control of the system, database management, and 3-D digital design are integrated into this digital model in the preliminary design stage of shipbuilding.

Experimental study of solid-liquid origami composite structures with improved impact resistance

In this paper,a liquid-solid origami composite design is proposed for the improvement of impact resistance.Employing this design strategy,Kresling origami composite structures with different fillings were designed and fabricated,namely air,water,and shear thickening fluid(STF).Quasi-static compression and drop-weight impact experiments were carried out to compare and reveal the static and dynamic mechanical behavior of these structures.The results from drop-weight impact experiments demonstrated that the solid-liquid Kresling origami composite structures exhibited superior yield strength and reduced peak force when compared to their empty counterparts.Notably,the Kresling origami structures filled with STF exhibited significantly heightened yield strength and reduced peak force.For example,at an impact velocity of 3 m/s,the yield strength of single-layer STF-filled Kresling origami structures increased by 772.7%and the peak force decreased by 68.6%.This liquid-solid origami composite design holds the potential to advance the application of origami structures in critical areas such as aerospace,intelligent protection and other important fields.The demonstrated improvements in impact resistance underscore the practical viability of this approach in enhancing structural performance for a range of applications.

Resistive switching behavior and mechanism of HfO_(x) films with large on/off ratio by structure design

Different bilayer structures of HfO_(x)/Ti(TiO_(x)) are designed for hafnium-based memory to investigate the switching characteristics. The chemical states in the films and near the interface are characterized by x-ray photoelectron spectroscopy,and the oxygen vacancies are analyzed. Highly improved on/off ratio(~104) and much uniform switching parameters are observed for bilayer structures compared to single layer HfO_(x) sample, which can be attributed to the modulation of oxygen vacancies at the interface and better control of the growth of filaments. Furthermore, the reliability of the prepared samples is investigated. The carrier conduction behaviors of HfO_(x)-based samples can be attributed to the trapping and de-trapping process of oxygen vacancies and a filamentary model is proposed. In addition, the rupture of filaments during the reset process for the bilayer structures occur at the weak points near the interface by the recovery of oxygen vacancies accompanied by the variation of barrier height. The re-formation of fixed filaments due to the residual filaments as lightning rods results in the better switching performance of the bilayer structure.