Neural stem cells,which are capable of multi-potential differentiation and self-renewal,have recently been shown to have clinical potential for repairing central nervous system tissue damage.However,the theme trends a...Neural stem cells,which are capable of multi-potential differentiation and self-renewal,have recently been shown to have clinical potential for repairing central nervous system tissue damage.However,the theme trends and knowledge structures for human neural stem cells have not yet been studied bibliometrically.In this study,we retrieved 2742 articles from the PubMed database from 2013 to 2018 using "Neural Stem Cells" as the retrieval word.Co-word analysis was conducted to statistically quantify the characteristics and popular themes of human neural stem cell-related studies.Bibliographic data matrices were generated with the Bibliographic Item Co-Occurrence Matrix Builder.We identified 78 high-frequency Medical Subject Heading(MeSH)terms.A visual matrix was built with the repeated bisection method in gCLUTO software.A social network analysis network was generated with Ucinet 6.0 software and GraphPad Prism 5 software.The analyses demonstrated that in the 6-year period,hot topics were clustered into five categories.As suggested by the constructed strategic diagram,studies related to cytology and physiology were well-developed,whereas those related to neural stem cell applications,tissue engineering,metabolism and cell signaling,and neural stem cell pathology and virology remained immature.Neural stem cell therapy for stroke and Parkinson’s disease,the genetics of microRNAs and brain neoplasms,as well as neuroprotective agents,Zika virus,Notch receptor,neural crest and embryonic stem cells were identified as emerging hot spots.These undeveloped themes and popular topics are potential points of focus for new studies on human neural stem cells.展开更多
微博实体链接是把微博中给定的指称链接到知识库的过程,广泛应用于信息抽取、自动问答等自然语言处理任务(Natural language processing,NLP).由于微博内容简短,传统长文本实体链接的算法并不能很好地用于微博实体链接任务.以往研究大...微博实体链接是把微博中给定的指称链接到知识库的过程,广泛应用于信息抽取、自动问答等自然语言处理任务(Natural language processing,NLP).由于微博内容简短,传统长文本实体链接的算法并不能很好地用于微博实体链接任务.以往研究大都基于实体指称及其上下文构建模型进行消歧,难以识别具有相似词汇和句法特征的候选实体.本文充分利用指称和候选实体本身所含有的语义信息,提出在词向量层面对任务进行抽象建模,并设计一种基于词向量语义分类的微博实体链接方法.首先通过神经网络训练词向量模板,然后通过实体聚类获得类别标签作为特征,再通过多分类模型预测目标实体的主题类别来完成实体消歧.在NLPCC2014公开评测数据集上的实验结果表明,本文方法的准确率和召回率均高于此前已报道的最佳结果,特别是实体链接准确率有显著提升.展开更多
基金supported by the National Natural Science Foundation of China,No.81471308(to JL)the Stem Cell Clinical Research Project in China,No.CMR-20161129-1003(to JL)the Innovation Technology Funding of Dalian in China,No.2018J11CY025(to JL)
文摘Neural stem cells,which are capable of multi-potential differentiation and self-renewal,have recently been shown to have clinical potential for repairing central nervous system tissue damage.However,the theme trends and knowledge structures for human neural stem cells have not yet been studied bibliometrically.In this study,we retrieved 2742 articles from the PubMed database from 2013 to 2018 using "Neural Stem Cells" as the retrieval word.Co-word analysis was conducted to statistically quantify the characteristics and popular themes of human neural stem cell-related studies.Bibliographic data matrices were generated with the Bibliographic Item Co-Occurrence Matrix Builder.We identified 78 high-frequency Medical Subject Heading(MeSH)terms.A visual matrix was built with the repeated bisection method in gCLUTO software.A social network analysis network was generated with Ucinet 6.0 software and GraphPad Prism 5 software.The analyses demonstrated that in the 6-year period,hot topics were clustered into five categories.As suggested by the constructed strategic diagram,studies related to cytology and physiology were well-developed,whereas those related to neural stem cell applications,tissue engineering,metabolism and cell signaling,and neural stem cell pathology and virology remained immature.Neural stem cell therapy for stroke and Parkinson’s disease,the genetics of microRNAs and brain neoplasms,as well as neuroprotective agents,Zika virus,Notch receptor,neural crest and embryonic stem cells were identified as emerging hot spots.These undeveloped themes and popular topics are potential points of focus for new studies on human neural stem cells.
文摘微博实体链接是把微博中给定的指称链接到知识库的过程,广泛应用于信息抽取、自动问答等自然语言处理任务(Natural language processing,NLP).由于微博内容简短,传统长文本实体链接的算法并不能很好地用于微博实体链接任务.以往研究大都基于实体指称及其上下文构建模型进行消歧,难以识别具有相似词汇和句法特征的候选实体.本文充分利用指称和候选实体本身所含有的语义信息,提出在词向量层面对任务进行抽象建模,并设计一种基于词向量语义分类的微博实体链接方法.首先通过神经网络训练词向量模板,然后通过实体聚类获得类别标签作为特征,再通过多分类模型预测目标实体的主题类别来完成实体消歧.在NLPCC2014公开评测数据集上的实验结果表明,本文方法的准确率和召回率均高于此前已报道的最佳结果,特别是实体链接准确率有显著提升.
