Altered bowel flora is currently thought to play a role in a variety of disease conditions, and the use of Bifidobacterium spp. and Lactobacillus spp. as probiotics has been demonstrated to be health-promoting, even i...Altered bowel flora is currently thought to play a role in a variety of disease conditions, and the use of Bifidobacterium spp. and Lactobacillus spp. as probiotics has been demonstrated to be health-promoting, even if the success of their administration depends on the applied bacterial strain（s） and the targeted disease. In the last few decades, specific probiotics have been shown to be effective in the treatment or the prevention of acute viral gastroenteritis, pediatric post-antibiotic-associated diarrhea, some pediatric allergic disorders, necrotizing enterocolitis in preterm infants, inflammatory bowel diseases and postsurgical pouchitis. The potential application of probiotics is continuously widening, with new evidence accumulating to support their effect on the prevention and treatment of other disease conditions, including several oral diseases, such as dental caries, periodontal diseases and oral malodor, as well as genitourinary and wound infections. Considering the increasingly widespread ability of pathogens to generate persistent biofilm-related infections, an even more attractive proposal is to administer probiotics to prevent or counteract biofilm development.The response of biofilm-based oral, intestinal, vaginal and wound infections to probiotics treatment will be reviewed here in light of the most recent results obtained in this field.展开更多
Chronic refractory w ounds are common and frequently-seen diseases in surgery.Due to their long course of disease and complex pathogeneses,chronic refractory w ounds arouse high attention in clinic.With the preliminar...Chronic refractory w ounds are common and frequently-seen diseases in surgery.Due to their long course of disease and complex pathogeneses,chronic refractory w ounds arouse high attention in clinic.With the preliminary results of clinical research of their pathogeneses and new treatments achieved,traditional Chinese medicine(TCM),w ith its unique concept,breaks the limitation commonly existing in the methods of w estern medicine,especially obtaining certain achievements in chronic refractory w ounds.This paper review ed the therapeutic effects of compound Baiyu pow der in the treatment of chronic refractory w ounds to prove to be effective,convenient to use and save medical costs.展开更多
目的:运用文献计量学与可视化分析,探索伤口生物膜的研究现状、热点及趋势。方法:检索Web of Science核心合集中伤口生物膜的相关文献,检索时间为2003年1月1日—2022年4月10日,采用VOSviewer、CiteSpace对检索结果进行分析。结果:共纳入...目的:运用文献计量学与可视化分析,探索伤口生物膜的研究现状、热点及趋势。方法:检索Web of Science核心合集中伤口生物膜的相关文献,检索时间为2003年1月1日—2022年4月10日,采用VOSviewer、CiteSpace对检索结果进行分析。结果:共纳入2050篇文献,综合指数排名居第1位的作者为丹麦的学者Bjarnsholt Thomas;载文量最多的期刊为Journal of Wound Care;发文量最多的国家为美国(679篇);发文量最多的机构是丹麦哥本哈根大学(40篇)。结论:伤口生物膜相关研究的主力在美国,焦点为伤口生物膜的种类、特性等基础研究及对抗生物膜的方法方面。未来需加强机构间的交流合作,多关注伤口生物膜的临床管理及其社会学评价等方面的研究。展开更多
文摘Altered bowel flora is currently thought to play a role in a variety of disease conditions, and the use of Bifidobacterium spp. and Lactobacillus spp. as probiotics has been demonstrated to be health-promoting, even if the success of their administration depends on the applied bacterial strain（s） and the targeted disease. In the last few decades, specific probiotics have been shown to be effective in the treatment or the prevention of acute viral gastroenteritis, pediatric post-antibiotic-associated diarrhea, some pediatric allergic disorders, necrotizing enterocolitis in preterm infants, inflammatory bowel diseases and postsurgical pouchitis. The potential application of probiotics is continuously widening, with new evidence accumulating to support their effect on the prevention and treatment of other disease conditions, including several oral diseases, such as dental caries, periodontal diseases and oral malodor, as well as genitourinary and wound infections. Considering the increasingly widespread ability of pathogens to generate persistent biofilm-related infections, an even more attractive proposal is to administer probiotics to prevent or counteract biofilm development.The response of biofilm-based oral, intestinal, vaginal and wound infections to probiotics treatment will be reviewed here in light of the most recent results obtained in this field.
基金Jiangsu Province Natural Science Foundation Item(BK20161606)Special Fund for Improving Academic Ability of Nursing of Integrated Traditional Chinese and Western Medicine(TG20180003d)
文摘Chronic refractory w ounds are common and frequently-seen diseases in surgery.Due to their long course of disease and complex pathogeneses,chronic refractory w ounds arouse high attention in clinic.With the preliminary results of clinical research of their pathogeneses and new treatments achieved,traditional Chinese medicine(TCM),w ith its unique concept,breaks the limitation commonly existing in the methods of w estern medicine,especially obtaining certain achievements in chronic refractory w ounds.This paper review ed the therapeutic effects of compound Baiyu pow der in the treatment of chronic refractory w ounds to prove to be effective,convenient to use and save medical costs.
文摘目的:运用文献计量学与可视化分析,探索伤口生物膜的研究现状、热点及趋势。方法:检索Web of Science核心合集中伤口生物膜的相关文献,检索时间为2003年1月1日—2022年4月10日,采用VOSviewer、CiteSpace对检索结果进行分析。结果:共纳入2050篇文献,综合指数排名居第1位的作者为丹麦的学者Bjarnsholt Thomas;载文量最多的期刊为Journal of Wound Care;发文量最多的国家为美国(679篇);发文量最多的机构是丹麦哥本哈根大学(40篇)。结论:伤口生物膜相关研究的主力在美国,焦点为伤口生物膜的种类、特性等基础研究及对抗生物膜的方法方面。未来需加强机构间的交流合作,多关注伤口生物膜的临床管理及其社会学评价等方面的研究。
