The relationship between noise variance and spatial resolution in grating-based x-ray phase computed tomography（PCT） imaging is investigated with reverse projection extraction method, and the noise variances of the ...The relationship between noise variance and spatial resolution in grating-based x-ray phase computed tomography（PCT） imaging is investigated with reverse projection extraction method, and the noise variances of the reconstructed absorption coefficient and refractive index decrement are compared. For the differential phase contrast method, the noise variance in the differential projection images follows the same inverse-square law with spatial resolution as in conventional absorption-based x-ray imaging projections. However, both theoretical analysis and simulations demonstrate that in PCT the noise variance of the reconstructed refractive index decrement scales with spatial resolution follows an inverse linear relationship at fixed slice thickness, while the noise variance of the reconstructed absorption coefficient conforms with the inverse cubic law. The results indicate that, for the same noise variance level, PCT imaging may enable higher spatial resolution than conventional absorption computed tomography（ACT）, while ACT benefits more from degraded spatial resolution. This could be a useful guidance in imaging the inner structure of the sample in higher spatial resolution.展开更多
基金Project supported by the National Basic Research Program of China(Grant No.2012CB825800)the Science Fund for Creative Research Groups,the Knowledge Innovation Program of the Chinese Academy of Sciences(Grant Nos.KJCX2-YW-N42 and Y4545320Y2)the National Natural Science Foundation of China(Grant Nos.11475170,11205157,11305173,11205189,11375225,11321503,11179004,and U1332109)
文摘The relationship between noise variance and spatial resolution in grating-based x-ray phase computed tomography（PCT） imaging is investigated with reverse projection extraction method, and the noise variances of the reconstructed absorption coefficient and refractive index decrement are compared. For the differential phase contrast method, the noise variance in the differential projection images follows the same inverse-square law with spatial resolution as in conventional absorption-based x-ray imaging projections. However, both theoretical analysis and simulations demonstrate that in PCT the noise variance of the reconstructed refractive index decrement scales with spatial resolution follows an inverse linear relationship at fixed slice thickness, while the noise variance of the reconstructed absorption coefficient conforms with the inverse cubic law. The results indicate that, for the same noise variance level, PCT imaging may enable higher spatial resolution than conventional absorption computed tomography（ACT）, while ACT benefits more from degraded spatial resolution. This could be a useful guidance in imaging the inner structure of the sample in higher spatial resolution.
