[Objectives]To observe the clinical effect of acupuncture on blepharospasm.[Methods]72 patients were randomly divided into treatment group and control group with 36 cases in each group.In the treatment group,Shenmai,Z...[Objectives]To observe the clinical effect of acupuncture on blepharospasm.[Methods]72 patients were randomly divided into treatment group and control group with 36 cases in each group.In the treatment group,Shenmai,Zhaohai,Fengchi,Taichong,Fuyang,Jiaoxin and Jingming were selected as the main acupoints,while in the control group,routine acupoints were selected.With 4 weeks as a course of treatment,the two groups were compared after a course of treatment.The clinical effect of primary blepharospasm,blepharospasm intensity and scores of Hamilton Depression Scale were compared between the two groups before and after treatment.[Results]After treatment,the clinical efficacy of the two groups were significantly improved compared with that before treatment,the effective rate of the control group was 75.00%,the effective rate of the treatment group was 88.89%,indicating that the effective rate of control group was lower than that of the treatment group(P<0.05);after treatment,the degree of blepharospasm in both groups was significantly lower than that before treatment(P<0.05),and the treatment group had better effect in improving primary blepharospasm;the score of Hamilton depression scale in control group was lower than that in observation group(P<0.05).[Conclusions]The clinical curative effect of acupuncture at Yinqiao and Yangqiao meridians was better than that of conventional acupoints selected in relieving mild and moderate blepharospasm;it could definitely reduce the intensity of blepharospasm and relieve anxiety and depression of patients,so it is worthy of clinical promotion.展开更多
目的 观察电针跷脉穴联合超声引导下冲击波和振动训练治疗卒中后肌痉挛的临床疗效及其对患者血清γ-氨基丁酸(γ-aminobutyric acid,GABA)和谷氨酸(glutamic acid,Glu)含量的影响。方法 采用随机数字表法将80例卒中后肌痉挛患者随机分...目的 观察电针跷脉穴联合超声引导下冲击波和振动训练治疗卒中后肌痉挛的临床疗效及其对患者血清γ-氨基丁酸(γ-aminobutyric acid,GABA)和谷氨酸(glutamic acid,Glu)含量的影响。方法 采用随机数字表法将80例卒中后肌痉挛患者随机分为研究组与对照组,每组40例。两组均接受康复训练,对照组另予振动训练及超声引导下冲击波治疗,研究组在对照组治疗基础上联合电针跷脉穴治疗。观察治疗前后两组中医证候积分各单项评分、Fugl-Meyer运动功能量表(Fugl-Meyer assessment,FMA)评分、卒中专用生活质量量表(stroke specific quality of life scale,SS-QOL)评分、上肢动作研究量表(action research arm test,ARAT)评分、美国国立卫生院卒中量表(National Institutes of Health stroke scale,NIHSS)评分和改良Barthel指数(modified Barthel index,MBI)评分的变化,观察治疗前后两组患者血清GABA和Glu水平的变化,比较两组临床疗效。结果 治疗后,两组中医证候积分各单项评分、FMA评分、SS-WOL评分、ARAT评分、NIHSS评分和MBI评分以及血清GABA和Glu水平均较治疗前改善(P<0.05)。研究组治疗后中医证候积分、NIHSS评分和血清Glu水平均低于对照组(P<0.05),SS-QOL、FMA、MBI和ARAT评分以及血清GABA水平均高于对照组(P<0.05)。研究组总有效率高于对照组(P<0.05)。结论 在康复训练基础上,电针跷脉穴联合超声引导下冲击波和振动训练治疗卒中后肌痉挛能有效改善患者的神经症状、生活质量与肢体运动能力,改善Glu和GABA表达水平,从而缓解肌肉痉挛症状,疗效优于单纯超声引导下冲击波和振动训练治疗。展开更多
文摘[Objectives]To observe the clinical effect of acupuncture on blepharospasm.[Methods]72 patients were randomly divided into treatment group and control group with 36 cases in each group.In the treatment group,Shenmai,Zhaohai,Fengchi,Taichong,Fuyang,Jiaoxin and Jingming were selected as the main acupoints,while in the control group,routine acupoints were selected.With 4 weeks as a course of treatment,the two groups were compared after a course of treatment.The clinical effect of primary blepharospasm,blepharospasm intensity and scores of Hamilton Depression Scale were compared between the two groups before and after treatment.[Results]After treatment,the clinical efficacy of the two groups were significantly improved compared with that before treatment,the effective rate of the control group was 75.00%,the effective rate of the treatment group was 88.89%,indicating that the effective rate of control group was lower than that of the treatment group(P<0.05);after treatment,the degree of blepharospasm in both groups was significantly lower than that before treatment(P<0.05),and the treatment group had better effect in improving primary blepharospasm;the score of Hamilton depression scale in control group was lower than that in observation group(P<0.05).[Conclusions]The clinical curative effect of acupuncture at Yinqiao and Yangqiao meridians was better than that of conventional acupoints selected in relieving mild and moderate blepharospasm;it could definitely reduce the intensity of blepharospasm and relieve anxiety and depression of patients,so it is worthy of clinical promotion.
文摘目的 观察电针跷脉穴联合超声引导下冲击波和振动训练治疗卒中后肌痉挛的临床疗效及其对患者血清γ-氨基丁酸(γ-aminobutyric acid,GABA)和谷氨酸(glutamic acid,Glu)含量的影响。方法 采用随机数字表法将80例卒中后肌痉挛患者随机分为研究组与对照组,每组40例。两组均接受康复训练,对照组另予振动训练及超声引导下冲击波治疗,研究组在对照组治疗基础上联合电针跷脉穴治疗。观察治疗前后两组中医证候积分各单项评分、Fugl-Meyer运动功能量表(Fugl-Meyer assessment,FMA)评分、卒中专用生活质量量表(stroke specific quality of life scale,SS-QOL)评分、上肢动作研究量表(action research arm test,ARAT)评分、美国国立卫生院卒中量表(National Institutes of Health stroke scale,NIHSS)评分和改良Barthel指数(modified Barthel index,MBI)评分的变化,观察治疗前后两组患者血清GABA和Glu水平的变化,比较两组临床疗效。结果 治疗后,两组中医证候积分各单项评分、FMA评分、SS-WOL评分、ARAT评分、NIHSS评分和MBI评分以及血清GABA和Glu水平均较治疗前改善(P<0.05)。研究组治疗后中医证候积分、NIHSS评分和血清Glu水平均低于对照组(P<0.05),SS-QOL、FMA、MBI和ARAT评分以及血清GABA水平均高于对照组(P<0.05)。研究组总有效率高于对照组(P<0.05)。结论 在康复训练基础上,电针跷脉穴联合超声引导下冲击波和振动训练治疗卒中后肌痉挛能有效改善患者的神经症状、生活质量与肢体运动能力,改善Glu和GABA表达水平,从而缓解肌肉痉挛症状,疗效优于单纯超声引导下冲击波和振动训练治疗。