BACKGROUND The quality-adjusted life year(QALY)is a metric that is increasingly used today in the field of health economics to evaluate the value of different medical treatments and procedures.Surgical waiting lists(S...BACKGROUND The quality-adjusted life year(QALY)is a metric that is increasingly used today in the field of health economics to evaluate the value of different medical treatments and procedures.Surgical waiting lists(SWLs)represent a pressing problem in public healthcare.The QALY measure has rarely been used in the context of surgery.It would be interesting to know how many QALYs are lost by patients on SWLs.AIM To investigate the relationship between QALYs and SWLs in a systematic review of the scientific literature.METHODS The study was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Statement.An unlimited search was carried out in PubMed,updated on January 19,2024.Data on the following variables were investigated and analyzed:Specialty,country of study,procedure under study,scale used to measure QALYs,the use of a theoretical or real-life model,objectives of the study and items measured,the economic value assigned to the QALY in the country in question,and the results and conclusions published.RESULTS Forty-eight articles were selected for the study.No data were found regarding QALYs lost on SWLs.The specialties in which QALYs were studied the most in relation to the waiting list were urology and general surgery,with 15 articles each.The country in which the most studies of QALYs were carried out was the United States(n=21),followed by the United Kingdom(n=9)and Canada(n=7).The most studied procedure was organ transplantation(n=39),including 15 kidney,14 liver,5 heart,4 lung,and 1 intestinal.Arthroplasty(n=4),cataract surgery(n=2),bariatric surgery(n=1),mosaicplasty(n=1),and septoplasty(n=1)completed the surgical interventions included.Thirty-nine of the models used were theoretical(the most frequently applied being the Markov model,n=34),and nine were real-life.The survey used to measure quality of life in 11 articles was the European Quality of Life-5 dimensions,but in 32 articles the survey was not specified.The willingness-to-pay per QALY gained ranged from$100000 in the United States to€20000 in Spain.CONCLUSION The relationship between QALYs and SWLs has only rarely been studied in the literature.The rate of QALYs lost on SWLs has not been determined.Future research is warranted to address this issue.展开更多
The year of 1994 was a milestone on a historical road of the textile trade development worldwide. The Final Act concluding the Uruguay Round and officially establishing the WTO regime was signed during ministerial mee...The year of 1994 was a milestone on a historical road of the textile trade development worldwide. The Final Act concluding the Uruguay Round and officially establishing the WTO regime was signed during ministerial meeting at Marrakesh, Morroco on the 15th of April, 1994, and hence is known as the Marrakesh Agreement. That marked a beginning of quota phase out. China has been on a resolute stance to trade restrictions and protectionism all through quota phase out and post-quota period and will continue to do so when safeguard deal terminates…展开更多
This year marks 30th year commemoration of China's" reform and opening up" policy, the strategic decision made at the 3rd plenarysession of the national party congress' 11th central committee of Comm...This year marks 30th year commemoration of China's" reform and opening up" policy, the strategic decision made at the 3rd plenarysession of the national party congress' 11th central committee of Communist Party of China (CPC) in Dec. 1978. History made its way to the end of 1978. In December of that particular year, CPC leaders tapped on the table to decide to open up and reform this long-encapsulated country in a milestone conclusion. Thirty years elapsed. Like many other industrial sectors that benefited from this monumental decision, Chinese textile industry has undeniably been growing at a fantastic speed, and its export is on an unrivalled growth in phase...展开更多
In line with the overall Objectives set out in the"Outline Scheme for the Academic Divisions of theChinese Academy of Sciences (CAS) during theNinth Five-year Plan (1996-2000)," CAS has donea good job of the...In line with the overall Objectives set out in the"Outline Scheme for the Academic Divisions of theChinese Academy of Sciences (CAS) during theNinth Five-year Plan (1996-2000)," CAS has donea good job of the supplementary election of CASmembers and the development of the virtues ofscience and fine style of research. In addihon, con-sultation and appraisal, academic exchanges, andthe popularization of science have progressivelybeen focuses of the academic divisions, and manyaccomplishments have been achieved in these areas.展开更多
During the 12^(th)Five-Year Plan period,the environmental protection information work made remarkable achievements,and the construction of nationwide air quality monitoring network was completed; the trinitarian monit...During the 12^(th)Five-Year Plan period,the environmental protection information work made remarkable achievements,and the construction of nationwide air quality monitoring network was completed; the trinitarian monitoring system was established,and environmental emergency command ability enhanced significantly. However,the issues of " information island" and " application silo" are still outstanding,and the application and promotion of new technologies make slow progress; the capacity of information system to support environmental protection business is insufficient,and there is no capacity for decision analysis. In the 13^(th)Five-Year Plan period,it is needed to strengthen the application and promotion of new technologies such as cloud computing,big data,Internet of Things,and spatial information,mainly construct and improve " Cloud Computing Based Environmental Protection( CCBEP) ", " big data platform of ecological environment",and then realize the core objective of improving environmental quality.展开更多
Systemic lupus erythematosus(SLE)is an autoimmune disease with extreme heterogeneity and potentially involvement of any organ or system.Numerous unanswered questions and challenges in SLE always prompt further explora...Systemic lupus erythematosus(SLE)is an autoimmune disease with extreme heterogeneity and potentially involvement of any organ or system.Numerous unanswered questions and challenges in SLE always prompt further exploration.In 2019,great progress in various aspects of SLE emerged.Both the classification criteria and management recommendation for SLE were updated.New promising medications have been widely developed and tested,although subsequent clinical studies are warranted.As an emerging number of most notable studies in SLE were published in both clinical area and basic research in 2019,we aim to summarize the highest quality data on SLE regarding novel insights of pathogenesis,updated recommendations,hot-spot issues on clinical manifestations,new understanding of disease prognosis,and most importantly,the therapeutic advances in SLE in this review.展开更多
Objective To assess the progress in the treatment of advanced childhood neuroblastoma.Methods From 1981 to 1996, there were 32 children with neuroblastoma (NB) diagnosed, staged and treated in our institution. There w...Objective To assess the progress in the treatment of advanced childhood neuroblastoma.Methods From 1981 to 1996, there were 32 children with neuroblastoma (NB) diagnosed, staged and treated in our institution. There were 4 patients with stage Ⅱ NB (12%), 5 stage Ⅲ (16%), 21 stage Ⅳ (66%) and 2 stage Ⅳs (6%). The NBs were excised if CT scan indicated that the tumors were operable. For advanced NB, stages Ⅲ and Ⅳ, multiple drug chemotherapy was started first and operability was assessed with serial CT scan examinations. Once the X-ray imaging indicated the tumors were operable, surgical interventions were done. The medical records of the advanced NB were reviewed.Results In the initial period of the study, 9 patients were treated using the VAC protocol [vincristine (vcr), adriamycin(adria) and cyclophosphamide (cyc)]. No patient was convertible to operable and all died with a mean survival of 10 months. OPEC [vcr, cyc, VM26, cisplatin (cis)], Rapid COJEC (carboplatin, VP16, vcr, cis and cyc) and more recently N6 protocol (cyc, adria, vcr, VP16, cis) was used for 17 patients. 80% of them were converted to operable. In 4 patients, surgical specimens showed only necrotic tissue without viable tumor tissue and 6 (35%) tumors were converted to ganglioneuroma or ganglioneuroblastoma. Although 2 (12%) patients died of fungal septicemia and 1 (6%) developed Fanconi's syndrome after chemotherapy, the mean survival period increased to 27 months. In the 10 survivors (60%), 4 had megatherapy with melphalan followed by autologous peripheral blood stem cell (PBSC) transplantation and 2 were waiting for transplantation. Conclusions There is a high percentage of advanced NB on presentation in Hong Kong. With more potent multiple drug chemotherapy for advanced stage NB there are (1) improvement in the survival of these patients, (2) opportunities for more operations for tumor excision and (3) opportunities for autologous PBSC transplantation for better tumor eradication.展开更多
The development of Journal of Palaeogeography depends on support from scholars and specialists.Names of scholars and specialists as reviewers for Journal of Palaeogeography in year 2012-2013 are listed below(numbers i...The development of Journal of Palaeogeography depends on support from scholars and specialists.Names of scholars and specialists as reviewers for Journal of Palaeogeography in year 2012-2013 are listed below(numbers in the brackets are reviewing times).Great gratitude is extended to them!展开更多
The founding of China Institute of Chinese Medicine, known now as the China Academy of Chinese Medical Sciences, was proclaimed in December 1955 in Beijing. Premier ZHOU En-lai commemorated the occasion with his inscr...The founding of China Institute of Chinese Medicine, known now as the China Academy of Chinese Medical Sciences, was proclaimed in December 1955 in Beijing. Premier ZHOU En-lai commemorated the occasion with his inscription extolling "to carry forward the heritage of Chinese medicine". Just before and after its establishment, the Academy recruited numbers of famous Chinese and Western medicine specialists all over the country to participate in this endeavour.展开更多
In the last 10 years, China has madeconsiderable progress in urbanization withincreasing numbers of both city and urbanpopulation. This has played a positive rolein promoting the country’s political, eco-nomic and cu...In the last 10 years, China has madeconsiderable progress in urbanization withincreasing numbers of both city and urbanpopulation. This has played a positive rolein promoting the country’s political, eco-nomic and cultural development. However,the process of urbanization has broughtalong new problems and contradictionswhich require theoretical exploration.Against this background, urban sociology,展开更多
This paper, excerpted from General President Gao Yan’s Speech on the State Power Corporation Working Conference for 2001, held in Shenzhen on December 23-25, 2000, reviews the power production and construction tasks ...This paper, excerpted from General President Gao Yan’s Speech on the State Power Corporation Working Conference for 2001, held in Shenzhen on December 23-25, 2000, reviews the power production and construction tasks in 2000 and puts forward the major targets and focal tasks of power production and construction for 2001.展开更多
Growth rate of oil demand rose again in China in the first half of 2015. Demand for oil products went on differentiating, and the demand growth of most products sped up. Growth rate of oil production rose again, oil i...Growth rate of oil demand rose again in China in the first half of 2015. Demand for oil products went on differentiating, and the demand growth of most products sped up. Growth rate of oil production rose again, oil imports increased rapidly, and external dependence of crude oil and oil broke through 60% separately. The State adjusted the prices of gasoline and diesel timely and frequently, based on pricing mechanism. Price hike was higher than reduction. Oil market got weak, yet more stable. China increased the pace of reforms in marketization. In the second half, oil demand will increase continuously but with lower growth rate, oil production will rise more slowly, imports of crude oil and oil will keep on rising rapidly, gasoline and kerosene as well as diesel will witness a net import, and the market of gasoline, kerosene and diesel will be more stable.展开更多
With the effort of all Editorial Board members and reviewers of the Virologica Sinica(VS),the journal got great progress in the year 2015.VS has been newly indexed by SCIE and the yearly download times on Springerlink...With the effort of all Editorial Board members and reviewers of the Virologica Sinica(VS),the journal got great progress in the year 2015.VS has been newly indexed by SCIE and the yearly download times on Springerlink have reached the highest record in its history.The Editors of the Virologica Sinica would like to thank all the following reviewers for their excellent work for展开更多
文摘BACKGROUND The quality-adjusted life year(QALY)is a metric that is increasingly used today in the field of health economics to evaluate the value of different medical treatments and procedures.Surgical waiting lists(SWLs)represent a pressing problem in public healthcare.The QALY measure has rarely been used in the context of surgery.It would be interesting to know how many QALYs are lost by patients on SWLs.AIM To investigate the relationship between QALYs and SWLs in a systematic review of the scientific literature.METHODS The study was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Statement.An unlimited search was carried out in PubMed,updated on January 19,2024.Data on the following variables were investigated and analyzed:Specialty,country of study,procedure under study,scale used to measure QALYs,the use of a theoretical or real-life model,objectives of the study and items measured,the economic value assigned to the QALY in the country in question,and the results and conclusions published.RESULTS Forty-eight articles were selected for the study.No data were found regarding QALYs lost on SWLs.The specialties in which QALYs were studied the most in relation to the waiting list were urology and general surgery,with 15 articles each.The country in which the most studies of QALYs were carried out was the United States(n=21),followed by the United Kingdom(n=9)and Canada(n=7).The most studied procedure was organ transplantation(n=39),including 15 kidney,14 liver,5 heart,4 lung,and 1 intestinal.Arthroplasty(n=4),cataract surgery(n=2),bariatric surgery(n=1),mosaicplasty(n=1),and septoplasty(n=1)completed the surgical interventions included.Thirty-nine of the models used were theoretical(the most frequently applied being the Markov model,n=34),and nine were real-life.The survey used to measure quality of life in 11 articles was the European Quality of Life-5 dimensions,but in 32 articles the survey was not specified.The willingness-to-pay per QALY gained ranged from$100000 in the United States to€20000 in Spain.CONCLUSION The relationship between QALYs and SWLs has only rarely been studied in the literature.The rate of QALYs lost on SWLs has not been determined.Future research is warranted to address this issue.
文摘The year of 1994 was a milestone on a historical road of the textile trade development worldwide. The Final Act concluding the Uruguay Round and officially establishing the WTO regime was signed during ministerial meeting at Marrakesh, Morroco on the 15th of April, 1994, and hence is known as the Marrakesh Agreement. That marked a beginning of quota phase out. China has been on a resolute stance to trade restrictions and protectionism all through quota phase out and post-quota period and will continue to do so when safeguard deal terminates…
文摘This year marks 30th year commemoration of China's" reform and opening up" policy, the strategic decision made at the 3rd plenarysession of the national party congress' 11th central committee of Communist Party of China (CPC) in Dec. 1978. History made its way to the end of 1978. In December of that particular year, CPC leaders tapped on the table to decide to open up and reform this long-encapsulated country in a milestone conclusion. Thirty years elapsed. Like many other industrial sectors that benefited from this monumental decision, Chinese textile industry has undeniably been growing at a fantastic speed, and its export is on an unrivalled growth in phase...
文摘In line with the overall Objectives set out in the"Outline Scheme for the Academic Divisions of theChinese Academy of Sciences (CAS) during theNinth Five-year Plan (1996-2000)," CAS has donea good job of the supplementary election of CASmembers and the development of the virtues ofscience and fine style of research. In addihon, con-sultation and appraisal, academic exchanges, andthe popularization of science have progressivelybeen focuses of the academic divisions, and manyaccomplishments have been achieved in these areas.
文摘During the 12^(th)Five-Year Plan period,the environmental protection information work made remarkable achievements,and the construction of nationwide air quality monitoring network was completed; the trinitarian monitoring system was established,and environmental emergency command ability enhanced significantly. However,the issues of " information island" and " application silo" are still outstanding,and the application and promotion of new technologies make slow progress; the capacity of information system to support environmental protection business is insufficient,and there is no capacity for decision analysis. In the 13^(th)Five-Year Plan period,it is needed to strengthen the application and promotion of new technologies such as cloud computing,big data,Internet of Things,and spatial information,mainly construct and improve " Cloud Computing Based Environmental Protection( CCBEP) ", " big data platform of ecological environment",and then realize the core objective of improving environmental quality.
基金supported by grants from the National Natural Science Foundation of China(Nos.91442120,81771740)。
文摘Systemic lupus erythematosus(SLE)is an autoimmune disease with extreme heterogeneity and potentially involvement of any organ or system.Numerous unanswered questions and challenges in SLE always prompt further exploration.In 2019,great progress in various aspects of SLE emerged.Both the classification criteria and management recommendation for SLE were updated.New promising medications have been widely developed and tested,although subsequent clinical studies are warranted.As an emerging number of most notable studies in SLE were published in both clinical area and basic research in 2019,we aim to summarize the highest quality data on SLE regarding novel insights of pathogenesis,updated recommendations,hot-spot issues on clinical manifestations,new understanding of disease prognosis,and most importantly,the therapeutic advances in SLE in this review.
文摘Objective To assess the progress in the treatment of advanced childhood neuroblastoma.Methods From 1981 to 1996, there were 32 children with neuroblastoma (NB) diagnosed, staged and treated in our institution. There were 4 patients with stage Ⅱ NB (12%), 5 stage Ⅲ (16%), 21 stage Ⅳ (66%) and 2 stage Ⅳs (6%). The NBs were excised if CT scan indicated that the tumors were operable. For advanced NB, stages Ⅲ and Ⅳ, multiple drug chemotherapy was started first and operability was assessed with serial CT scan examinations. Once the X-ray imaging indicated the tumors were operable, surgical interventions were done. The medical records of the advanced NB were reviewed.Results In the initial period of the study, 9 patients were treated using the VAC protocol [vincristine (vcr), adriamycin(adria) and cyclophosphamide (cyc)]. No patient was convertible to operable and all died with a mean survival of 10 months. OPEC [vcr, cyc, VM26, cisplatin (cis)], Rapid COJEC (carboplatin, VP16, vcr, cis and cyc) and more recently N6 protocol (cyc, adria, vcr, VP16, cis) was used for 17 patients. 80% of them were converted to operable. In 4 patients, surgical specimens showed only necrotic tissue without viable tumor tissue and 6 (35%) tumors were converted to ganglioneuroma or ganglioneuroblastoma. Although 2 (12%) patients died of fungal septicemia and 1 (6%) developed Fanconi's syndrome after chemotherapy, the mean survival period increased to 27 months. In the 10 survivors (60%), 4 had megatherapy with melphalan followed by autologous peripheral blood stem cell (PBSC) transplantation and 2 were waiting for transplantation. Conclusions There is a high percentage of advanced NB on presentation in Hong Kong. With more potent multiple drug chemotherapy for advanced stage NB there are (1) improvement in the survival of these patients, (2) opportunities for more operations for tumor excision and (3) opportunities for autologous PBSC transplantation for better tumor eradication.
文摘The development of Journal of Palaeogeography depends on support from scholars and specialists.Names of scholars and specialists as reviewers for Journal of Palaeogeography in year 2012-2013 are listed below(numbers in the brackets are reviewing times).Great gratitude is extended to them!
文摘The founding of China Institute of Chinese Medicine, known now as the China Academy of Chinese Medical Sciences, was proclaimed in December 1955 in Beijing. Premier ZHOU En-lai commemorated the occasion with his inscription extolling "to carry forward the heritage of Chinese medicine". Just before and after its establishment, the Academy recruited numbers of famous Chinese and Western medicine specialists all over the country to participate in this endeavour.
文摘In the last 10 years, China has madeconsiderable progress in urbanization withincreasing numbers of both city and urbanpopulation. This has played a positive rolein promoting the country’s political, eco-nomic and cultural development. However,the process of urbanization has broughtalong new problems and contradictionswhich require theoretical exploration.Against this background, urban sociology,
文摘This paper, excerpted from General President Gao Yan’s Speech on the State Power Corporation Working Conference for 2001, held in Shenzhen on December 23-25, 2000, reviews the power production and construction tasks in 2000 and puts forward the major targets and focal tasks of power production and construction for 2001.
文摘Growth rate of oil demand rose again in China in the first half of 2015. Demand for oil products went on differentiating, and the demand growth of most products sped up. Growth rate of oil production rose again, oil imports increased rapidly, and external dependence of crude oil and oil broke through 60% separately. The State adjusted the prices of gasoline and diesel timely and frequently, based on pricing mechanism. Price hike was higher than reduction. Oil market got weak, yet more stable. China increased the pace of reforms in marketization. In the second half, oil demand will increase continuously but with lower growth rate, oil production will rise more slowly, imports of crude oil and oil will keep on rising rapidly, gasoline and kerosene as well as diesel will witness a net import, and the market of gasoline, kerosene and diesel will be more stable.
文摘With the effort of all Editorial Board members and reviewers of the Virologica Sinica(VS),the journal got great progress in the year 2015.VS has been newly indexed by SCIE and the yearly download times on Springerlink have reached the highest record in its history.The Editors of the Virologica Sinica would like to thank all the following reviewers for their excellent work for