OBJECTIVE: To study the use of Jianjining in the treatment of myasthenia gravis (MG) patients with a deficiency of both spleen and kidney via the theory on the combination of disease with syndrome. METHODS: Sixty MG p...OBJECTIVE: To study the use of Jianjining in the treatment of myasthenia gravis (MG) patients with a deficiency of both spleen and kidney via the theory on the combination of disease with syndrome. METHODS: Sixty MG patients with a deficiency of both spleen and kidney were randomly divided into an treatment group (n=30) treated with Jianjining granules and Western Medicine (prednisone or pyridostigmine bromide) and a control group (n= 30) treated with Jianjining granules. The dosage of the three drugs was reduced over the course of treatment. After 3 and 6 months of treatment, the curative effect was evaluated with the muscle weakness severity scale (MWSS). RESULTS: The MWSS score after treatment declined significantly in both groups. The score in the treatment group was much lower than that in thecontrol group (P<0.05). The total effective rate was 63.33% (19/30) in the treatment group and 36.67% (11/30) in the control group after 3 months of treatment, and 80.00% (24/30) and 50.00% (15/30), respectively, after 6 months of treatment. The obvious and total effective rates in the treatment group were much higher than those in the control group (P<0.05). After 6 months of treatment, there were no obvious differences (P>0.05) in the obvious and effective rates between the 2 groups. However, the total effective rate in the treatment group was much higher than that in the control group (P<0.01). CONCLUSION: Using the theory on the combination of disease with syndrome, we found that the curative effect of Jianjining and Western Medicine on MG patients with deficiency of both spleen and kidney is worth further exploration.展开更多
目的分析从脾论治针灸治疗气阴亏虚型2型糖尿病的临床疗效。方法80例气阴亏虚型2型糖尿病患者,随机编号后利用计算机随机抽取方式分为对照组和实验组,每组40例。对照组接受常规针刺治疗和药物干预,实验组在对照组基础上给予益气健脾针...目的分析从脾论治针灸治疗气阴亏虚型2型糖尿病的临床疗效。方法80例气阴亏虚型2型糖尿病患者,随机编号后利用计算机随机抽取方式分为对照组和实验组,每组40例。对照组接受常规针刺治疗和药物干预,实验组在对照组基础上给予益气健脾针刺治疗。比较两组治疗效果及治疗前后血糖指标水平。结果治疗后,实验组空腹血糖(FBG)、餐后2 h血糖(2 h PG)及糖化血红蛋白(HbA1c)水平分别为(5.12±2.16)mmol/L、(8.17±1.62)mmol/L、(5.73±0.13)%;对照组分别为(6.53±2.67)mmol/L、(10.12±2.63)mmol/L、(5.99±0.31)%。治疗后,实验组FBG、2 h PG及HbA1c水平低于对照组,差异有统计学意义(P<0.05)。实验组治疗总有效率为97.5%,高于对照组的85.0%,差异有统计学意义(P<0.05)。结论气阴亏虚型2型糖尿病患者运用从脾论治针灸治疗方案,从益气健脾角度出发,可对患者起到益气健脾效果,帮助患者将临床各项血糖指标控制在合理范围,增强免疫力,提高胰岛素敏感性,减轻体重,促进其康复治疗进程,值得应用和推广。展开更多
基金Supported by a Key Project in Basic Research of Shanghai Municipal Committee of Science(No.10JC1414500)a Planned Project in the TCM Fund of Scientific Research under the Shanghai Municipal Health Bureau (2010J002B)
文摘OBJECTIVE: To study the use of Jianjining in the treatment of myasthenia gravis (MG) patients with a deficiency of both spleen and kidney via the theory on the combination of disease with syndrome. METHODS: Sixty MG patients with a deficiency of both spleen and kidney were randomly divided into an treatment group (n=30) treated with Jianjining granules and Western Medicine (prednisone or pyridostigmine bromide) and a control group (n= 30) treated with Jianjining granules. The dosage of the three drugs was reduced over the course of treatment. After 3 and 6 months of treatment, the curative effect was evaluated with the muscle weakness severity scale (MWSS). RESULTS: The MWSS score after treatment declined significantly in both groups. The score in the treatment group was much lower than that in thecontrol group (P<0.05). The total effective rate was 63.33% (19/30) in the treatment group and 36.67% (11/30) in the control group after 3 months of treatment, and 80.00% (24/30) and 50.00% (15/30), respectively, after 6 months of treatment. The obvious and total effective rates in the treatment group were much higher than those in the control group (P<0.05). After 6 months of treatment, there were no obvious differences (P>0.05) in the obvious and effective rates between the 2 groups. However, the total effective rate in the treatment group was much higher than that in the control group (P<0.01). CONCLUSION: Using the theory on the combination of disease with syndrome, we found that the curative effect of Jianjining and Western Medicine on MG patients with deficiency of both spleen and kidney is worth further exploration.
文摘目的分析从脾论治针灸治疗气阴亏虚型2型糖尿病的临床疗效。方法80例气阴亏虚型2型糖尿病患者,随机编号后利用计算机随机抽取方式分为对照组和实验组,每组40例。对照组接受常规针刺治疗和药物干预,实验组在对照组基础上给予益气健脾针刺治疗。比较两组治疗效果及治疗前后血糖指标水平。结果治疗后,实验组空腹血糖(FBG)、餐后2 h血糖(2 h PG)及糖化血红蛋白(HbA1c)水平分别为(5.12±2.16)mmol/L、(8.17±1.62)mmol/L、(5.73±0.13)%;对照组分别为(6.53±2.67)mmol/L、(10.12±2.63)mmol/L、(5.99±0.31)%。治疗后,实验组FBG、2 h PG及HbA1c水平低于对照组,差异有统计学意义(P<0.05)。实验组治疗总有效率为97.5%,高于对照组的85.0%,差异有统计学意义(P<0.05)。结论气阴亏虚型2型糖尿病患者运用从脾论治针灸治疗方案,从益气健脾角度出发,可对患者起到益气健脾效果,帮助患者将临床各项血糖指标控制在合理范围,增强免疫力,提高胰岛素敏感性,减轻体重,促进其康复治疗进程,值得应用和推广。
