Clinical evaluation of testicular torsion presenting with acute abdominal pain in young males

Objective:To evaluate the features of testicular torsion presenting with acute abdominal pain and to raise awareness of testicular torsion with specific symptoms.Methods:From October 2005 to June 2016,nine patients with testicular torsion who presented with isolated acute abdominal pain rather than scrotal pain as their primary symptom were retrospectively reviewed.Data,including the age of patients,season at admission,initial medical history,external genital examination,emergency ultrasound findings,operative findings,duration of abdominal pain,complications,and follow-up results,were collected.Results:The average age of patients was 14 years(range 10-17 years).Seven patients whose genitals were not initially examined externally were misdiagnosed as having ordinary abdominal diseases.Surgical exploration revealed that all the involved testes necrotized,and orchidectomy was performed.In the other two patients,scrotal and testicular abnormalities were detected immediately on admission,and emergency surgical exploration determined that the involved testis remained vital,so orchiopexy was performed.The mean duration from symptom onset to diagnosis was 4 h(3-5 h)in the orchiopexy group and 37 h(18-72 h)in the orchidectomy group.Six patients were psychologically affected during postoperative follow-up.Neither recurrence of testicular torsion nor testicular atrophy was recorded.Conclusion:Acute abdominal pain can be the initial and sole symptom of testicular torsion in young males.Physicians should pay close attention to the specific clinical presentation of testicular torsion.

Psychological stress and long-term blood pressure variability of military young males:The cardiorespiratory fitness and hospitalization events in armed forces study

BACKGROUND Acute stress might increase short-term heart rate variability and blood pressure variability(BPV);however,chronic stress would not alter short-term BPV in animal models.AIM To examine the association of psychological stress with long-term BPV in young male humans.METHODS We prospectively examined the association of chronic psychological stress with long-term BPV in 1112 healthy military males,averaged 32.2 years from the cardiorespiratory fitness and hospitalization events in armed forces study in Taiwan.Psychological stress was quantitatively evaluated with the Brief Symptom Rating Scale(BSRS-5),from the least symptom of 0 to the most severe of 20,and the five components of anxiety,insomnia,depression,interpersonal sensitivity,and hostility(the severity score in each component from 0 to 4).Longterm BPV was assessed by standard deviation(SD)for systolic and diastolic blood pressure(SBP and DBP),and average real variability(ARV),defined as the average absolute difference between successive measurements of SBP or DBP,across four visits in the study period from 2012 to 2018(2012-14,2014-15,2015-16,and 2016-18).RESULTS The results of multivariable linear regressions showed that there were no correlations of the BSRS-5 score with SDSBP,SDDBP,ARVSBP,and ARVDBP after adjusting for all the covariates[β(SE):-0.022(0.024),-0.023(0.026),-0.001(0.018),and 0.001(0.020),respectively;P>0.05 for all].In addition,there were also no correlations between each component of the BSRS score and the long-term BPV indexes.CONCLUSION Our findings suggest that chronic psychological stress might not be associated with long-term BPV in military young male humans.

Choroidal vascular occlusion in a young male patient with sickle cell trait

Dear Editor,Choroidal vascular occlusion is a rare finding. Choroidal perfusion disorders may range from focal infarction of the choriocapillaris to fibrinoid arteriolar necrosis. Vascular occlusion due to microembolism is more common in choroidal than in retinal vasculature. Due to its unique hemodynamic characteristics, which involve one of the highest rates of blood flow in the body and the fact that it is functionally an end artery system, the choroidal circulation is prone to platelet emboli associated with cardiovascular disease and other pathologies with increased risk of microembolismt.

Metabolic biomarkers and long-term blood pressure variability in military young male adults

BACKGROUND Metabolic syndrome is a cluster of cardiovascular risk factors, including central obesity, high blood pressure, elevated plasma glucose, reduced high-density lipoprotein and elevated triglyceride levels.AIM To investigate the relationship between metabolic biomarkers and long-term blood pressure variability(BPV) in young males.METHODS A cohort of 1112 healthy military males aged 18-40 years from the cardiorespiratory fitness and hospitalization events in armed forces study in eastern Taiwan was prospectively included. The following metabolic biomarkers were used: Waist circumference, serum uric acid(SUA), triglycerides, high density lipoprotein, triglycerides, and fasting glycose. BPV was assessed by average real variability(ARV) and standard deviation(SD) across 4 clinic visits during the study period(2012-14, 2014-15, 2015-16, and 2016-18). Multivariable linear regression analysis was used to determine the association after adjusting for age, body mass index, systolic and diastolic blood pressure(SBP and DBP),lipid profiles, physical activity, alcohol intake and tobacco smoking status.RESULTS In the unadjusted model, waist circumference was significantly and positively correlated with ARVDBP and SDDBP [β(standard errors) = 0.16(0.049) and 0.22(0.065), respectively], as was SUA [β = 0.022(0.009) and 0.038(0.012),respectively]. High-density lipoprotein was negatively correlated with ARVSBP [β=-0.13(0.063)]. There were no associations with the other metabolic biomarkers.In contrast, only SUA was significantly correlated with SDSBP and SDDBP [β = 0.019(0.011) and 0.027(0.010), respectively] in the adjusted model.CONCLUSION Our findings showed that of traditional metabolic biomarkers, SUA had the strongest positive correlation with long-term systolic and diastolic BPV in young male adults, and the clinical relevance needs further investigation.

Prevalence of HBs Antigen, and HCV and HIV Antibodies in a Young Male Population in Cameroon

Introduction: According to WHO estimates, 57% of cases of liver cirrhosis and 78% of primary liver carcinoma are caused by a hepatitis B or C virus. This study aimed to assess the prevalence of these diseases and HIV among a young male population, according to region. Methods: This was a descriptive cross-sectional study conducted from 17 February to 31 March 2014 in the ten administrative regions of Cameroon. The study included male subjects of Cameroonian nationality aged at least 18 and at most 23, and living in the regions concerned. It excluded subjects that did not match the age, gender, and nationality criteria. For each subject, 10 ml of blood was collected in a dry tube. After centrifugation at 3000 RPM for 5 minutes, the serum was collected for the detection of viral infections. For subjects that tested positive, a confirmatory test was conducted. Results: In total, 4367 subjects were selected, with an average age of 20.46 (+/- 1.17) years. The prevalence of hepatitis B virus stood at 13.01% (with 95% CI: 12.03% - 14.05%). That of viral hepatitis C was 0.30% (95% CI: 0.17% - 0.52%). Co-infection with hepatitis B and C viruses was 0.05% (95% CI: 0.01% - 0.18%). The prevalence of HIV infection was 1.01% (95% CI: 0.74% - 1.36%). Conclusion: The overall prevalence of HBsAg in the population of young males is high. It tallies with the early vertical and horizontal modes of transmission that prevail in our environment.

Mitochondrial haplogroups associated with Japanese centenarians, Alzheimer's patients, Parkinson's patients, type 2 diabetic patients and healthy non-obese young males

The relationships between five classes of Japanese people （i.e., 96 centenarians, 96 Alzheimer＇s disease （AD） patients, 96 Parkinson＇s disease （PD） patients, 96 type 2 diabetic （T2D） patients, and 96 healthy non-obese young males） and their mitochondrial single nucleotide polymorphism （mtSNP） frequencies at individual mtDNA positions of the entire mitochondrial genome were examined using the radial basis function （RBF） network and the modified method. New findings of mitochondrial haplogroups were obtained for individual classes. The five classes of people were associated with the following haplogroups： Japanese centenarians-M7b2, D4b2a, and B5b; Japanese AD patients-G2a, B4cl, and N9b1; Japanese PD patients-M7b2, B4e, and B5b; Japanese T2D patients-B5b, M8al, G, D4, and F1; and Japanese healthy non-obese young males-D4g and D4b1b. From the points of common haplogroups among the five classes, the cente- narians have the common haplogroups M7b2 and B5b with the PD patients and common haplogroup B5b with the T2D patients. In addition, the 112 Japanese semi-supercentenarians （over 105 years old） recently reported were also examined by the method proposed. The results obtained were the haplogroups D4a, B4c1a, M7b2, F1, M1, and B5b. These results are different from the previously reported haplogroup classifications. As the proposed analysis method can predict a person＇s mtSNP constitution and the probabilities of becoming a centenarian, AD patient, PD patient, or T2D patient, it may be useful in initial diagnosis of various diseases.

Visual Walkability in Wangjing Area from the Perspective of Young Men

This paper mainly evaluated the walkability of the streets around the subway Futong Station in Wangjing area,and with the help of relevant theoretical research conclusions such as environmental behavioral psychology,to study the effect of the visual walkability of streets in different communities on the walking activities of young male residents.Through in-depth analysis of the characteristics of streets that are suitable for walking and young male residents like to walk,practical and feasible reference suggestions were provided for the design of street public space and the establishment of a more livable urban environment.The text was divided into 3 parts:the determination of the functional types of the streets around Futong Station;the characteristics of young men's crowd activities and the establishment of an evaluation system;the visual walkability evaluation of the streets around Futong Station.

Complete rectal prolapse in young Egyptian males: Is schistosomiasis really condemned?

AIM To investigate the assumption that schistosomiasis is the main cause of rectal prolapse in young Egyptian males. METHODS Twenty-one male patients between ages of 18 and 50 years with complete rectal prolapse were included in the study out of a total 29 patients with rectal prolapse admitted for surgery at Colorectal Surgery Unit, Ain Shams University hospitals between the period of January 2011 and April 2014. Patients were asked to fill out a specifically designed questionnaire about duration of the prolapse, different bowel symptoms and any past or present history of schistosomiasis. Patients also underwent flexible sigmoidoscopy and four quadrant midrectal biopsies documenting any gross or microscopic rectal pathology. Data from questionnaire and pathology results were analyzed and patients were categorized according to their socioeconomic class.RESULTS Twelve patients(57%) never contracted schistosomiasis and were never susceptible to the disease, nine patients(43%) had history of the disease but were properly treated. None of the patients had gross rectal polypsand none of the patients had active schistosomiasis on histopathological examination. Fifteen patients(71%) had early onset prolapse that started in childhood, majority before the age of 5 years. Thirteen patients(62%) were habitual strainers, and four of them(19%) had straining dating since early childhood. Four patients(19%) stated that prolapse followed a period of straining that ranged between 8 mo and 2 years. Nine patients(43%) in the present study came from the low social class, 10 patients(48%) came from the working class and 2 patients(9%) came from the low middle social class. CONCLUSION Schistosomiasis should not be considered the main cause of rectal prolapse among young Egyptian males. Childhood prolapse that continues through adult life is likely involved. Childhood prolapse probably results from malnutrition, recurrent parasitic infections and diarrhea that induce straining and prolapse, all are common in lower socioeconomic classes.

Comparison of Tissue Transglutaminase Activity During Young Panicle Development in Honglian-type Cytoplasmic Male Sterile Rice

To investigate the changes of tissue transglutaminase activity, the leaves and young panicles of rice at different developmental stages were excised from the Honglian-type cytoplasmic male sterile line, Yuetai A and its maintainer line, Yuetai B, respectively. An ELISA measurement protocol for tissue transglutaminase activity detection in rice was well established. The results indicated that the tissue transglutaminase activity was regulated positively by calcium cation, and the tissue transglutaminase activity in senescent leaves was remarkably higher than that in young leaves. No distinct difference was noted between Yuetai A and Yuetai B. Moreover, from the tetrad to binucleate stages the tissue transglutaminase activity increased gradually with the progression of the young panicle development and up to maximum at binucleate stage in Yuetai A. However, no similar changes were observed in Yuetai B. This indicates that the tissue transglutaminase is involved in cell programmed death in abortive pollen.

排尿体位对青年男性尿流率和残余尿的影响

目的研究排尿体位对健康青年男性尿流测定(UFM)和残余尿(PVR)的影响,探讨男性更佳的排尿体位,为临床应用UFM评估膀胱功能和规范测定方法提供参考。方法对新乡医学院第一附属医院43名在校男性医学生(22~28岁,入学体检健康,无下尿路症状)分别于站立位、前弯曲坐位和坐位3种体位进行UFM,每次排尿后立即用B超测定PVR。比较3种体位排尿量(VV)、最大尿流率(Qmax)、平均尿流率(Qave)和PVR。结果参与者在站立位、前弯曲坐位和坐位的VV中位数分别为211.6(169.5,265.9)mL、206.8(173.5,262.8)mL和203.7(175.9,260.0)mL,三组间比较差异无统计学意义(P=0.486);Qmax分别为(26.00±2.33)mL/s、(26.41±2.12)mL/s和(23.50±2.52)mL/s;Qave分别为(14.03±2.21)mL/s、(14.27±2.18)mL/s和(11.77±1.89)mL/s;PVR分别为(9.97±2.26)mL、(9.43±1.97)mL和(12.10±3.28)mL,参与者在站立位和前弯曲坐位的Qmax、Qave高于坐位测定值,PVR低于坐位测定值,差异有统计学意义(P<0.05)。参与者在站立位与前弯曲坐位的Qmax、Qave和PVR差异均无统计学意义(P>0.05)。结论青年男性在站立位和前弯曲坐位均有利于排空膀胱,推荐这2种体位作为膀胱排尿的首选体位。

不同体重指数青年男性的静息能量消耗特点及预测方程评价

目的:探讨不同体重指数(body mass index,BMI)青年男性静息能量消耗(resting energy expenditure,REE)的特点,比较常见静息代谢率(resting metabolic rate,RMR)预测方程与间接测热法的差异。方法:以2017年12月至2021年6月于北京大学第三医院运动医学科进行静息代谢测试的30名青年男性为研究对象,采用间接测热法测定RMR,采用生物电阻抗法测定体成分。分析研究对象REE的特点,并与11个常见预测方程的推算值进行比较,通过配对t检验和组内相关系数(intra-class correlation coefficient,ICC)评估两者差异。结果:30名青年男性的平均年龄为(26.93±4.16)岁,整体RMR为(1960.17±463.11)kcal/d(1 kcal=4.1868 kJ),其中BMI正常者的RMR为(1744.33±249.62)kcal/d,显著低于超重或肥胖者[(2104.06±520.32)kcal/d](P<0.01),但体质量校正后,BMI正常者的RMR显著高于超重或肥胖者[(24.02±2.61)kcal/(kg·d)vs.(19.98±4.38)kcal/(kg·d),P<0.01];不同BMI受试者的RMR与体质量、脂肪量、去脂体重、体表面积、细胞外液呈显著正相关(P均<0.05)。11个预测方程的预测值与实测值的一致性均不佳(ICC均<0.75),其中,超重或肥胖青年男性采用世界卫生组织(World Health Organization,WHO)推荐使用的RMR预测方程的预测值与实测值的一致性相对较高(ICC=0.547,P<0.01)。结论:不同BMI青年男性的RMR存在显著差异,超重或肥胖者要考虑体质量矫正后的RMR情况。不同预测方程的预测值与RMR的实测值一致性较差,建议通过间接测热法准确测定RMR。对于超重和肥胖的青年男性可以考虑采用WHO推荐使用的预测方程计算RMR,但有必要建立适用于不同BMI人群的RMR预测方程。

青年男性颈肩部轮廓量化分析与形态匹配

以190名青年男大学生为研究对象,通过照片测量法、三维人体扫描法获取人体正侧面照片及三维点云数据。基于三维点云数据,提取颈肩部轮廓曲线进行椭圆傅立叶拟合得到椭圆系数,经主成分分析和聚类分析,将青年男性颈肩部正侧面形态各分为3类。采用角度半径和欧几里得距离实现二维照片与三维点云数据之间的匹配,并验证匹配准确率。结果显示:颈肩部正面轮廓匹配验证准确率达92.5%,侧面轮廓匹配验证准确率达95.0%。该研究为基于人体照片的人体形态研究提供了理论依据。

中青年男性握力与颈动脉粥样硬化的关联研究

目的 探讨中青年男性握力水平和颈动脉粥样硬化的关联,为运动干预动脉粥样硬化的发生发展提供依据。方法 招募454名20~59岁男性,记录人体学指标,测量身体成分、握力、心肺耐力和相关血液指标并进行颈动脉超声检查。采用t检验、单因素方差分析、Logistic回归进行统计学分析。结果 相比于低握力水平组,高握力水平组的BMI低、RSMI大、心率低、TC低、HDL低、空腹血糖低、CIMT小、Crouse积分小、等级积分小,差异均有统计学意义(均P<0.05)。Logistic回归分析显示,调整BMI、RSMI、心率、TC、HDL、空腹血糖、VO_(2max)、收缩压、舒张压后,低水平和中等水平组发生颈动脉粥样硬化的风险高于高水平组(OR=2.79、1.71)。结论 较低握力的中青年男性存在动脉粥样硬化的风险较高,握力测量有助于评估动脉粥样硬化状况。

基于角度半径的青年男子躯干部形态相似性匹配

为实现基于三维人体点云的人体形态相似性匹配,文章提出了利用角度半径进行青年男体躯干部轮廓形态描述的方法。先以187名18~25周岁的青年男大学生为研究对象,使用三维扫描法获取其三维点云数据。再通过逆向工程软件识别人体躯干部特征点,截取其正侧面躯干轮廓形态。然后分别建立正侧面躯干部坐标系,提取27个正面角度半径值和60个侧面角度半径值形成三维点云躯干形态数据库。选取14名被试者进行验证,提取的正、侧面角度半径为样本,采用均方根误差法与点云截面数据库进行匹配,并使用OpenCV框架中的MatchSharp法验证匹配结果。结果显示,13名被试者的躯干部正侧面轮廓形态与三维点云轮廓形态匹配成功,准确率达92.86%。研究结果可为三维点云形态相似性分析提供一定的理论基础。

“三击”理论视角下贵州省青少年男子武术散打运动员技术运用研究

为深入了解贵州省青少年男子武术散打运动员在比赛中技战术的运用现状,该文在“三击”理论视角下,从拳法、腿法、摔法方面,对2022年贵州省第十一届运动会竞技组青少年男子武术散打运动员的技术运用特征进行了分析。结果表明,贵州省青少年男子武术散打运动员腿法已成为主要得分技术,以鞭腿和正蹬腿为主,以侧踹和转身腿法为辅;拳法击打以冲拳为主,掼拳为辅;摔法技术主要以接拳摔之后双方先后倒地得1分和接腿摔击倒对方自己站立得2分为主。针对上述情况,该文指出了影响贵州省青少年男子武术散打运动员技术发挥的因素,并提出强化基本功训练,提高技术水平;注重拳腿组合技术的训练,提高得分能力;加强心理素质训练,提高比赛表现;丰富比赛经验,加强比赛策略等建议,以期为贵州省青少年男子武术散打运动员的训练提供理论参考依据。

Real case of primitive embryonal duodenal carcinoma in a young man

We report here the case of a young man suffering from a rare germ cell tumour. The patient was a 25-year-old man who was referred to our centre for asthenia, stinging epigastric pain, and an iron deficiency anaemia. Gastroscopy revealed a circumferential vegetating lesion on the second portion of the duodenum. The lesion was indurated at the third portion of the duodenum, responsible for a tight stenosis. A computerized tomography-scan of the chest, abdomen and pelvis, and a pancreatic MRI showed a circumferential lesion with a bi-ductal dilatation (i.e., of the common bile duct and Wirsung&#x02019;s duct) without metastatic localisation. The patient underwent a pancreaticoduodenectomy with lymph node dissection including all cellular adipose tissues of the hepatic pedicle from the hepatic common artery and of the retroportal lamina. Histological findings were suggestive of a duodenal embryonal carcinoma with pancreatic infiltration. This is the second published case highlighting the duodenal primitive localisation of an embryonal carcinoma with pancreatic infiltration.

Gender Differences in Coffee Consumption and Its Effects in Young People

This study aimed to examine gender differences in coffee consumption and awareness of its effects in young people. To examine the above problem, a survey was conducted in 1189 young people (567 males aged 19.3 ± 1.5 years;622 females aged 19.1 ± 1.2 years). The coffee consumption rate was significantly higher in males (50.8%) than in females (32.8%). In the coffee consumption group, no significant differences were found in the reasons for consumption, the components of coffee, and its effects on health. In the coffee nonconsumption group, significant gender differences were noted in the reasons for avoiding coffee;females (64.8%) disliked its taste more than males (39.4%). More young people of both genders in the consumption group were aware that coffee contains caffeine (79.9% - 86.5%) as compared with the nonconsumption group (67.0% - 74.2%). However, few people in both groups were aware about the components other than caffeine. In addition, more people in the nonconsumption group were unaware of the adverse effects of coffee on the body. The results of this study demonstrated that young males drink coffee more than young females. Among those who avoided coffee consumption, females disliked its taste more than males. Many people regardless of coffee consumption were aware about the components of coffee, but few knew about the other ingredients in this beverage. In addition, few people were aware of the negative effects of coffee on the health and body.

基于HSI彩色模型远程测量青年男体围度拟合

为实现人体远程测量系统的有效性,提出运用人体照片来预测青年男体的围度。通过HSI颜色空间转换、轮廓光滑处理等图像处理方法提取了人体轮廓。通过识别人体特征点,得到人体的体表角度、宽度和厚度;按照体表角度、厚度/宽度等指标进行人体体型分类。基于各个围度对应的厚度和宽度构建了颈围、胸围、腰围、腹围、臀围和大腿根围的围度拟合方程,并对拟合方程进行了误差分析。结果表明,建立的围度预测模型有效,保证了人体远程测量系统的可靠性。

青年男性肥胖相关基因单核苷酸多态性与精液质量参数的相关性分析

目的通过对青年男性肥胖相关基因(FTO基因)单核苷酸rs9930609多态性进行检测,探讨其对精液质量的影响,间接判断其是否是影响男性生育力的危险因素。方法选取2021年1月至12月在甘肃省妇幼保健院进行备孕前检查的122例肥胖青年男性与120例非肥胖青年男性作为研究对象。检测其精液质量及外周血FTO基因rs9930609(A/T)多态性,分析FTO基因单核苷酸多态性与精液质量参数变化的关系。结果AA型基因携带者的体重、体重指数(BMI)、精子密度、精子DNA碎片率(DFI)与AT及TT型基因携带者比较,差异具有统计学意义(P<0.05);精子密度<15×10~6/mL人群的AA型基因携带率为22.03%,高于精子密度≥15×10~6/mL人群13.66%的AA型基因携带率(P=0.022);DFI>15%人群的AA型基因携带率为30.28%,显著高于DFI≤15%人群11.94%的AA型基因携带率(P=0.002);AA型基因携带者发生肥胖的风险是TT型基因携带者的5.834倍(P=0.000);A等位基因携带者发生肥胖的风险是T等位基因携带者的3.832倍(P=0.003)。结论FTO基因rs9939609(A/T)多态性改变与精液参数具有相关性,AA型等位基因所介导的肥胖是导致精子密度异常、DFI异常的重要诱因,也是间接影响男性生育力的危险因素。对于存在精液质量异常的肥胖男性,检测其FTO基因rs9939609(A/T)多态性,将有助于制订更为有效的减肥措施,从而改善精子质量。

青年男性下尿路排尿功能障碍影像尿动力特点分析

目的探讨青年男性人群中下尿路排尿障碍影像尿流动力学检查结果、特点及对临床诊治的价值。方法收集2016年1月—2021年9月因下尿路排尿障碍就诊于甘肃省人民医院泌尿外科行影像尿动力的106例青年男性(18~45岁)患者的临床资料,分析其临床特点及影像尿动力特点。结果106例患者中,有明确的神经系统病变导致神经源性下尿路功能障碍患者55例(52.44%),非神经源性下尿路功能障碍患者51例(48%)。神经源性下尿路功能障碍患者中排尿困难是最常见的症状,占76.74%;腰骶部病变为主要原因(76.36%);影像尿动力主要诊断为逼尿肌肌力不同程度的减弱。非神经源性下尿路功能障碍患者中主要症状为尿频(48.72%)、排尿困难(48.72%),存在2个及2个以上下尿路症状的患者约58.97%,主要诊断为逼尿肌无力(35.90%)。结论青年男性神经源性下尿路功能障碍多为逼尿肌肌力不同程度的减弱、逼尿肌括约肌协调失调及膀胱顺应性降低;非神经源性多为逼尿肌过度活动(DO)及逼尿肌无力。