Zinc and copper intakes and serum concentrations were determined at the 32th and 36th week of pregnancy in 96 healthy Thai women attending a prenatal clinic. Dietary data from 3-day food records revealed that the mean...Zinc and copper intakes and serum concentrations were determined at the 32th and 36th week of pregnancy in 96 healthy Thai women attending a prenatal clinic. Dietary data from 3-day food records revealed that the mean dietary zinc and copper intakes in Thai pregnant women were 6. 9 and 1. 7mg/d (equivalent to 34 and 69% of Thai RDA), respectively. Fifty-five percent of zinc intake was from animal origin, whereas 59% of copper intake was from plant origin.The infants of the 64 women who were in the study until delivery, were all normal.Most (>96%) of the maternal serum zinc and copper concentrations were within normal ranges. Only one woman at 32th week had low serum zinc level (<6. 4μmol/L). There were no significant correlations between the maternal serum zinc or copper levels and pregnancy outcome (birth weight and birth length). In this study, although the zinc and copper intake in most Thai pregnant women (99 and 58%, respectively) were less than two-thirds of the Thai RDAs, they were not at risk of suffering from zinc and copper deficiencies as determined by serum zine and copper concentrations, abnormal parturition and abnormal pregnancy outcome.展开更多
Abstract Zinc （Zn） and copper （Cu） concentrations were determined in the tissues （muscle, stomach, liver, gills, skin, and gonads） of five commercial fish species （mullet Liza haematocheilus, flathead Platyceph...Abstract Zinc （Zn） and copper （Cu） concentrations were determined in the tissues （muscle, stomach, liver, gills, skin, and gonads） of five commercial fish species （mullet Liza haematocheilus, flathead Platycephalus indicus, mackerel Scomberomorus niphonius, silver pomfret Pampus argenteus, and sea bass Lateolabrax japonicus） from Laizhou Bay in the Bohai Sea. Metal bioaccumulation was highest in the metabolically active tissues of the gonads and liver. Bioconcentration factors for Zn were higher in all tissues （gonads 44.35, stomach 7.73, gills 7.72, liver 5.61, skin 4.88, and muscle 1.63） than the corresponding values for Cu （gonads 3.50, stomach 3.00, gills 1.60, liver 5.43, skin 1.50, and muscle 0.93）. Mackerel tissues accumulated metal to higher concentrations than did other fish species, but bioaccumulation levels were not significantly correlated with the trophic levels of the fish. Zn and Cu concentrations in the tissues were generally negatively correlated with fish length, except for a few tissues of sea bass. Risk assessment based on national and international permissible limits and provisional tolerances for weekly intake of Zn and Cu revealed that the concentrations of these two metals in muscle were relatively low and would not pose hazards to human health.展开更多
173 simultaneous determinations of serum copper levels (SCL), serum zinc levels (SZL) and copper/zinc ratio (CZR) were made by atomic absorption spectrophotometry in 51 previously untreated lymphoma patients. SCL and ...173 simultaneous determinations of serum copper levels (SCL), serum zinc levels (SZL) and copper/zinc ratio (CZR) were made by atomic absorption spectrophotometry in 51 previously untreated lymphoma patients. SCL and CZR were significantly higher in patients before treatment (mean value 22.97 μmol/L, 1.55, respectively) and in those who did not reach complete remission (mean 21.21 μmol/L, 1.36) as compared with the patients in complete remission (mean 16.36 μmol/L, 1.06) or normal controls (mean 15.67 μmol/L, 0.98). The mean value of SCL and CZR of patients in complete remission did not differ significantly from those of normal controls. Patients in stages HI and IV had higher SCL and CZR (mean 25.15 μmol/L, 1.79) than those in stage Ⅰ and Ⅱ (mean 19.30 μmol/L, 1.16). No significant difference in SZL was observed between the patient groups and normal controls. Thus, SCL and CZR may be used as prognostic indicators for monitoring disease activity and response to therapy in malignant lymphoma.展开更多
文摘Zinc and copper intakes and serum concentrations were determined at the 32th and 36th week of pregnancy in 96 healthy Thai women attending a prenatal clinic. Dietary data from 3-day food records revealed that the mean dietary zinc and copper intakes in Thai pregnant women were 6. 9 and 1. 7mg/d (equivalent to 34 and 69% of Thai RDA), respectively. Fifty-five percent of zinc intake was from animal origin, whereas 59% of copper intake was from plant origin.The infants of the 64 women who were in the study until delivery, were all normal.Most (>96%) of the maternal serum zinc and copper concentrations were within normal ranges. Only one woman at 32th week had low serum zinc level (<6. 4μmol/L). There were no significant correlations between the maternal serum zinc or copper levels and pregnancy outcome (birth weight and birth length). In this study, although the zinc and copper intake in most Thai pregnant women (99 and 58%, respectively) were less than two-thirds of the Thai RDAs, they were not at risk of suffering from zinc and copper deficiencies as determined by serum zine and copper concentrations, abnormal parturition and abnormal pregnancy outcome.
基金Supported by the National Natural Science Foundation of China for Creative Research Group(No.41121064)the International or Regional Research Cooperation and Exchange Project(No.31061160187)
文摘Abstract Zinc （Zn） and copper （Cu） concentrations were determined in the tissues （muscle, stomach, liver, gills, skin, and gonads） of five commercial fish species （mullet Liza haematocheilus, flathead Platycephalus indicus, mackerel Scomberomorus niphonius, silver pomfret Pampus argenteus, and sea bass Lateolabrax japonicus） from Laizhou Bay in the Bohai Sea. Metal bioaccumulation was highest in the metabolically active tissues of the gonads and liver. Bioconcentration factors for Zn were higher in all tissues （gonads 44.35, stomach 7.73, gills 7.72, liver 5.61, skin 4.88, and muscle 1.63） than the corresponding values for Cu （gonads 3.50, stomach 3.00, gills 1.60, liver 5.43, skin 1.50, and muscle 0.93）. Mackerel tissues accumulated metal to higher concentrations than did other fish species, but bioaccumulation levels were not significantly correlated with the trophic levels of the fish. Zn and Cu concentrations in the tissues were generally negatively correlated with fish length, except for a few tissues of sea bass. Risk assessment based on national and international permissible limits and provisional tolerances for weekly intake of Zn and Cu revealed that the concentrations of these two metals in muscle were relatively low and would not pose hazards to human health.
文摘173 simultaneous determinations of serum copper levels (SCL), serum zinc levels (SZL) and copper/zinc ratio (CZR) were made by atomic absorption spectrophotometry in 51 previously untreated lymphoma patients. SCL and CZR were significantly higher in patients before treatment (mean value 22.97 μmol/L, 1.55, respectively) and in those who did not reach complete remission (mean 21.21 μmol/L, 1.36) as compared with the patients in complete remission (mean 16.36 μmol/L, 1.06) or normal controls (mean 15.67 μmol/L, 0.98). The mean value of SCL and CZR of patients in complete remission did not differ significantly from those of normal controls. Patients in stages HI and IV had higher SCL and CZR (mean 25.15 μmol/L, 1.79) than those in stage Ⅰ and Ⅱ (mean 19.30 μmol/L, 1.16). No significant difference in SZL was observed between the patient groups and normal controls. Thus, SCL and CZR may be used as prognostic indicators for monitoring disease activity and response to therapy in malignant lymphoma.
