Through densified surface sampling of foraminifera and accurate elevation measurement a-long three transect lines in open-coast tidal salt-marsh of Jianchuan, particular salt-marsh foraminifera assemblages were found....Through densified surface sampling of foraminifera and accurate elevation measurement a-long three transect lines in open-coast tidal salt-marsh of Jianchuan, particular salt-marsh foraminifera assemblages were found. The salt-marsh foraminifera assemblages are distributed in well-defined vertical zonations with respect to elevation and closely parallel marsh floral zonations. At the top of the vertical zonation all foraminifera disappear abruptly which are accurately located at the highest high water datum. This distribution pattern can be used to relocate former sea levels accurately (to an accuracy of within ±5 cm). A modern regional criterion of foraminifera for relocating the former sea levels in high resolution in our country is provided, and deficiencies of studying the vertical zonation only in sheltered coast salt-marsh abroad are filled up.展开更多
Weathering crust reservoirs have obvious vertical zonation,which is the focus of weathering crust reservoir research,but there is a lack of quantitative characterization indexes.To achieve the quantitative characteriz...Weathering crust reservoirs have obvious vertical zonation,which is the focus of weathering crust reservoir research,but there is a lack of quantitative characterization indexes.To achieve the quantitative characterization of granite weathering crust reservoir and provide the basis for oil exploration of granite weathering crust buried hill reservoir,in this paper,the vertical zonation of granite weathering crust reservoir is quantitatively divided by testing and analyzing the uniaxial compressive strength(UCS),magnetic susceptibility(MS),permeability,and chemical index of alteration(CIA)of the Mesozoic granite weathering crust in the coastal area of eastern Fujian.The results show that the granite weathering crust reservoir can be divided into four zones vertically:a soil zone(SZ),weathered and dissolved zone(WDZ),fracture zone(FZ),and bedrock zone(BZ).A cataclastic area is developed in the FZ and BZ,in which structural fractures are well-developed,the fracture surface density is usually greater than 200 m/m^(2),and the contribution to the fractures in the rock mass is up to about 50%,making this the sweet spot of the reservoir.In the SZ,the rocks are loose,and the pores are well-developed.The UCS is less than 10 MPa,and the average rate of change of the UCS(Δ_(σ))is 0.90.The average permeability is 2823.00 mD,and the average rate of change of the permeability(Δ_(κ))is 5.13.The average CIA is 74.9%.The average clay mineral content is 7%.The rocks in the WDZ have been significantly weathered by physical and chemical processes,and the weathering fractures and dissolution pores are well-developed.The average UCS is 18.2 MPa,and the averageΔ_(σ)is 0.70.The average permeability is 143.80 mD,and averageΔ_(κ)is 4.17.The average CIA is 65.3%.The average clay mineral content is 4%.Under the influence of tectonic movement and physical weathering,the rocks in the FZ have developed structural fractures and a few weathered fractures.The average UCS is 57.9 MPa,and the averageΔ_(σ)is 0.18.The average permeability is 5.50 mD,and the averageΔ_(κ)is 2.55.The average CIA is 61.6%.The average clay mineral content is 2%.In the BZ,the rocks are intact and hard.The average UCS is 69.9 MPa,and the average Ds is 0.13.The average permeability is 1.46 mD,and the averageΔ_(κ)is 1.43.The average CIA is 57.8%.The average clay mineral content is less than 1%.The multi-parameter combination of the UCS,Δ_(σ),permeability,Δ_(κ),CIA,and clay mineral content achieved good results in the division of the zones of the weathering crust.The UCS increases gradually from top to bottom,while Ds,permeability,Δ_(κ),CIA,and clay mineral content all decrease gradually.In addition,based on the petrophysical parameters of the rocks,including the density,resistivity,and acoustic velocity,a good division effect was also achieved,which can provide a basis for the vertical zonation of the granite buried-hill weathering crust reservoir.展开更多
Parkinson's disease(PD)is a chronic progressive neurodegenerative disease.Deep brain stimulation(DBS)is an effective treatment for patients with advanced PD.There are many DBS targets for PD,including subthalamic ...Parkinson's disease(PD)is a chronic progressive neurodegenerative disease.Deep brain stimulation(DBS)is an effective treatment for patients with advanced PD.There are many DBS targets for PD,including subthalamic nucleus(STN),globus pallidus(GPi),meso-ventral thalamic nucleus(VIM),pontine peduncle nucleus(PPN),posterior subthalamic region(PSA)and zonation of undetermined zone(ZI).This paper summarizes the efficacy of each target in the treatment of PD with DBS,not only makes a systematic analysis and comparison of motor symptoms,but also makes a detailed description of the efficacy of non-motor symptoms,so as to provide a personalized treatment basis for PD patients to select appropriate target targets in DBS.展开更多
Since 1985, samples with a total weight of more than 14,000 kg, mainly from three key sections in western and northwestern Hunan, South China, have been processed for conodonts. In strata older than the late Late Camb...Since 1985, samples with a total weight of more than 14,000 kg, mainly from three key sections in western and northwestern Hunan, South China, have been processed for conodonts. In strata older than the late Late Cambrian paraconodonts have proved useful for stratigraphic subdivision and correlation. Thirteen conodont zones are proposed in the Middle Cambrian through lowermost Ordovician. The correlation between these zones and those of North China, western U. S.A., western Newfoundland, Canada, and Iran is discussed. In ascending order, these 13 zones are as follows: The Gapparodus bisulcatus-Westergaardodina brevidens Zone, Shandongodus priscus-Hunanognathus tricuspidatus Zone, Westergaardodina quadrata Zone, Westergaardodina matsushitai-W. grandidens Zone, Westergaardodina lui-W. am Zone, Westergaardodina cf. calix-Prooneotodus rotundatus Zone, Proconodontus tenuiserratus Zone, Proconodontus Zone, Eoconodontus Zone, Cordylodus proavus Zone, Cordylodus intermedius Zone, Cordylodus lindstromi Zone, and Cordylodus angulatus Zone (lower part). The Westergaardodina lui-W. ani and Westergaardodina cf. calix-Prooneotodus rotundatus Zones replace the Westergaardodina proligula and Westergaardodina cf. behrae-Prooneotodus rotundatus Zones, respectively, in the lowermost Upper Cambrian. Two new species (Westergaardodina Iui and Westergaardodina ani) and one conditionally identified species (Westergaardodina cf. calix) are described.展开更多
Forest fire is a major cause of changes in forest structure and function. Among various floristic regions, the northeast region of India suffers maximum from the fires due to age-old practice of shifting cultivation a...Forest fire is a major cause of changes in forest structure and function. Among various floristic regions, the northeast region of India suffers maximum from the fires due to age-old practice of shifting cultivation and spread of fires from jhum fields. For proper mitigation and management, an early warning of forest fires through risk modeling is required. The study results demonstrate the potential use of remote sensing and Geographic Information System (GIS) in identifying forest fire prone areas in Manipur, southeastern part of Northeast India. Land use land cover (LULC), vegetation type, Digital elevation model (DEM), slope, aspect and proximity to roads and settlements, factors that influence the behavior of fire, were used to model the forest fire risk zones. Each class of the layers was given weight according to their fire inducing capability and their sensitivity to fire. Weighted sum modeling and ISODATA clustering was used to classify the fire zones. TO validate the results, Along Track Scanning Radiometer (ATSR), the historical fire hotspots data was used to check the occurrence points and modeled forest fire locations. The forest risk zone map has 55-63% of agreement with ATSR dataset.展开更多
Field investigation and seismic section explanation showed that the Longmen Mountain Thrust Belt has obvious differential deformation: zonation, segmentation and stratification. Zonation means that, from NW to NE, th...Field investigation and seismic section explanation showed that the Longmen Mountain Thrust Belt has obvious differential deformation: zonation, segmentation and stratification. Zonation means that, from NW to NE, the Longmen Mountain Thrust Belt can be divided into the Songpan- Garz~ Tectonic Belt, ductile deformation belt, base involved thrust belt, frontal fold-thrust belt, and foreland depression. Segmentation means that it can be divided into five segments from north to south: the northern segment, the Anxian Transfer Zone, the center segment, the Guanxian Transfer Zone and the southern segment. Stratification means that the detachment layers partition the structural styles in profile. The detachment layers in the Longmen Mountain Thrust Belt can be classified into three categories: the deep-level detachment layers, including the crust-mantle system detachment layer, intracrustal detachment layer, and Presinian system basal detachment layer; the middle-level detachment layers, including Cambrian-Ordovician detachment layer, Silurian detachment layer, etc.; and shallow-level detachment layers, including Upper Triassic Xujiahe Formation detachment layer and the Jurassic detachment layers. The multi-level detachment layers have a very important effect on the shaping and evolution of Longmen Mountain Thrust Belt.展开更多
Through the field survey, previous researches and interpretation of aerial photos, a landslide information database of Xiaojiang Valley, Yunnan Province was set up based on the remote sensing (RS) and geographic infor...Through the field survey, previous researches and interpretation of aerial photos, a landslide information database of Xiaojiang Valley, Yunnan Province was set up based on the remote sensing (RS) and geographic information system (GIS) technologies. In the paper, a quantitative model for the landslide hazard assessment and zoning was presented, in which the potential energy could be obtained on basis of thorough analysis of the potential sliding volume, distance and direction of the landslide body. Taking landslide potential energy as the index of the hazard severity zonation, the study area was divided into severe, heavy, medium and light hazard zones.展开更多
The Pulang (普朗) porphyry copper deposit, located in the southern segment of the Yidun-Zhongdian (义敦-中甸) island arc ore-forming belt of the Tethys-Himalaya ore-forming domain, is a recently discovered large c...The Pulang (普朗) porphyry copper deposit, located in the southern segment of the Yidun-Zhongdian (义敦-中甸) island arc ore-forming belt of the Tethys-Himalaya ore-forming domain, is a recently discovered large copper deposit. Compared with the composition of granodiorite in China, the porphyry rocks in this area are enriched in W, Mo, Cu, Au, As, Sb, F, V, and Na2O (K1≥1.2). Compared with the composition of fresh porphyry rocks in this district, the mineralized rocks are enriched in Cu, Au, Ag, Mo, Pb, Zn, W, As, Sb, and K2O (K2≥1.2). Some elements show clear anomalies, such as Zn, Ag, Cu, Au, W, and Mo, and can be regarded as pathfinders for prospecting new ore bodies in depth. It has been inferred from factor analysis that the Pulang porphyry copper deposit may have undergone the multiple stages of alteration and mineralization: (a) Cu-Au mineralization; (b) W-Mo mineralization; and (c) silicification and potassic metasomatism in the whole ore-forming process. A detailed zonation sequence of indicator elements is obtained using the variability index of indicator elements as follows: Zn→Ag→Cu→Au→W→Mo. According to this zonation, an index such as (Ag*Zn)D/(Mo×W)D can be constructed and regarded as a significant criterion for predicting the Cu potential at a particular depth.展开更多
This paper explores the methodology for compiling the torrent hazard and risk zonation map by means of GIS technique for the Red River Basin in Yunnan province of China, where is prone to torrent. Based on a 1:250,00...This paper explores the methodology for compiling the torrent hazard and risk zonation map by means of GIS technique for the Red River Basin in Yunnan province of China, where is prone to torrent. Based on a 1:250,000 scale digital map, six factors including slope angle, rainstorm days, buffer of river channels, maximum runoff discharge of standard area, debris flow distribution density and flood disaster history were analyzed and superimposed to create the torrent risk evaluation map. Population density, farmland percentage, house property, and GDP as indexes accounting for torrent hazards were analyzed in terms of vulnerability mapping. Torrent risk zonation by means of GIS was overlaid on the two data layers of hazard and vulnerability. Then each grid unit with a resolution of 500 m- 500 m was divided into four categories of the risk: extremely high, high, moderate and low. Finally the same level risk was combined into a confirmed zone, which represents torrent risk of the study area. The risk evaluation result in the upper Red River Basin shows that the extremely high risk area of 13,150 km^2 takes up 17.9% of the total inundated area, the high risk area of 33,783 km^2 is 45.9%, the moderate risk area of 18,563 km^2 is 25.2% and the low risk area of 8115 km^2 is 11.0%.展开更多
The groundwater table has been declining at a rate of 0.65 m/yr in Luancheng County since large scale groundwater extraction carried out in the 1960s. The drop of precipitation, substantial increase in agricultural ou...The groundwater table has been declining at a rate of 0.65 m/yr in Luancheng County since large scale groundwater extraction carried out in the 1960s. The drop of precipitation, substantial increase in agricultural output, variations of crop planting structure and construction of water conservancy projects in the headwater area all tie up with the decline of the groundwater table. On the basis of analyzing the hydrogeological conditions and the water resources utilization of Luancheng County, a three-dimensional groundwater flow model was developed to simulate the county抯 groundwater flow through finite-difference method using Visual Modflow software. We divide the research field into four parts after analyzing the hydrogeological condition. Based on parameter calibration and adjustment using measured data, the hydraulic conductivity and specific yield were simulated. Using the calibrated model, we analyze the agricultural water saving potentiality and its influence on the groundwater. The results are as follows: (1) if we decrease the amount of water extracted by 0.14×108 m3, the average groundwater table of the five observation wells in December will rise by 0.33 m; (2) if we decrease the water by 0.29×108 m3, the average groundwater table of the five observation wells in December will rise by 0.64 m; and (3) if we increase the water by 0.29×108 m3, the average groundwater table of the five observation wells in December will decline by 0.45 m. So we can draw a conclusion that controlling the agricultural water use is an important way to prevent the decline of groundwater table.展开更多
Liver zonation,the spatial separation of the immense spectrum of different metabolic pathways along the liver sinusoids,is fundamental for proper functioning of this organ.Recent progress in elucidating localization a...Liver zonation,the spatial separation of the immense spectrum of different metabolic pathways along the liver sinusoids,is fundamental for proper functioning of this organ.Recent progress in elucidating localization and interactions of different metabolic pathways by using"omics"techniques and novel approaches to couple them with refined spatial resolution and in characterizing novel master regulators of zonation by using transgenic mice has created the basis for a deeper understanding of core mechanisms of zonation and their impact on liver physiology,pathology and metabolic diseases.This review summarizes the fascinating technical achievements for investigating liver zonation and the elucidation of an emerging network of master regulators of zonation that keep the plethora of interrelated and sometimes opposing functions of the liver in balance with nutritional supply and specific requirements of the entire body.In addition,a brief overview is given on newly described zonated functions and novel details on how diverse the segmentation of metabolic zonation may be.From these facts and developments a few fundamental principles are inferred which seem to rule zonation of liver parenchyma.In addition,we identify important questions that still need to be answered as well as interesting fields of research such as the connection of zonation with circadian rhythm and gender dimorphism which need to be pushed further,in order to improve our understanding of metabolic zonation.Finally,an outlook is given on how disturbance of liver zonation and its regulation may impact on liver pathology and the development of metabolic diseases.展开更多
Intertidal marine macroalgae experience periodical exposures during low tide due to their zonational distribution. The duration of such emersion leads to different exposures of the plants to light and aerial CO2, whic...Intertidal marine macroalgae experience periodical exposures during low tide due to their zonational distribution. The duration of such emersion leads to different exposures of the plants to light and aerial CO2, which then affect the physiology of them to different extents. The ecophysiological responses to light and CO2 were investigated during emersion in two red algae Gloiopeltis furcata and Gigartina intermedia, and two brown algae Petalonia fascia and Sargassum hemiphyllum, growing along the Shantou coast of China. The light-saturated net photosynthesis in G. furcata and P. fascia showed an increase followed by slightly desiccation, whereas that in G. intermedia and S. hemiphyllumexhibited a continuous decrease with water loss. In addition, the upper-zonated G. furcata and P. fascia, exhibited higher photosynthetic tolerance to desiccation and required higher light level to saturate their photosynthesis than the lower-zonated G. intermedia and S. hemiphyllum. Desiccation had less effect on dark respiration in these four algae compared with photosynthesis. The light-saturated net photosynthesis increased with increased CO2 concentrations, being saturated at CO2 concentrations higher than the present atmospheric level in G. furcata, G. intermedia and S. hemiphyllum during emersion. It was evident that the relative enhancement of photosynthesis by elevated CO2 in those three algae increased, though the absolute values of photosynthetic enhancement owing to CO2 increase were reduced when the desiccation statuses became more severe. However, in the case of desiccated P. fascia (water loss being greater than 20 %), light saturated net photosynthesis was saturated with current ambient atmospheric CO2 level. It is proposed that increasing atmospheric CO2 will enhance the daily photosynthetic production in intertidal macroalgae by varied extents that were related to the species and zonation.展开更多
Mineralogical zonation of wall rock alterations in Mesozoic granitoids is summarized from 18 gold deposits in Jiaodong gold province on the Asian mobile continental margin of the west circum Pacific rim. This paper ...Mineralogical zonation of wall rock alterations in Mesozoic granitoids is summarized from 18 gold deposits in Jiaodong gold province on the Asian mobile continental margin of the west circum Pacific rim. This paper deals with wall rock alterations developed around gold mineralizations of the quartz vein type in granitoids and the wall rock alteration type in granitoid basement contacts along Mesozoic fault zones trending mostly NNE SSW and NE SW. Five alteration zones are distinguished from host rock to ore zone, namely the chloritization and sericitization zone, the hematitization rutilization and microclinization zone, the quartz sericitization zone, the pyrite quartz sericitization zone and the pyrite silicification zone. The former two are outer zones marked by incomplete alteration of first mafic and then felsic minerals of the granitoids, while the later three are inner zones marked by complete alteration of both mafic and felsic minerals of the granitoids leading to retrogressive sericitization and progressive silicification with participation of ore elements. The whole process proceeds under dynamometamorphism with high fugacity of volatiles. Wall rock alteration is the intermediate link between unaltered host rock and ore mineralization both in time and space. Development of the alteration zonation and its mineral composition controls genetic type of mineralization, size and grade of the deposit and location of the ore zones.展开更多
Hepatocellular carcinoma(HCC) is the 3^(rd) leading cause of cancer-related death worldwide. More than 80% of HCCs arise within chronic liver disease resulting from viral hepatitis, alcohol, hemochromatosis, obesity a...Hepatocellular carcinoma(HCC) is the 3^(rd) leading cause of cancer-related death worldwide. More than 80% of HCCs arise within chronic liver disease resulting from viral hepatitis, alcohol, hemochromatosis, obesity and metabolic syndrome or genotoxins. Projections based on Western lifestyle and its metabolic consequences anticipate a further increase in incidence, despite recent breakthroughs in the management of viral hepatitis. HCCs display high heterogeneity of molecular phenotypes, which challenges clinical management. However, emerging molecular classifications of HCCs have not yet formed a unified corpus translatable to the clinical practice. Thus, patient management is currently based upon tumor number, size, vascular invasion, performance status and functional liver reserve. Nonetheless, an impressive body of molecular evidence emerged within the last 20 years and is becoming increasingly available to medical practitioners and researchers in the form of repositories. Therefore, the aim this work is to review molecular data underlying HCC classifications and to organize this corpus into the major dimensions explaining HCC phenotypic diversity. Major efforts have been recently made worldwide toward a unifying "clinically-friendly" molecular landscape. As a result, a consensus emerges on three major dimensions explaining the HCC heterogeneity. In the first dimension, tumor cell proliferation and differentiation enabled allocation of HCCs to two major classes presenting profoundly different clinical aggressiveness. In the second dimension, HCC microenvironment and tumor immunity underlie recent therapeutic breakthroughs prolonging patients' survival. In the third dimension,metabolic reprogramming, with the recent emergence of subclass-specific metabolic profiles, may lead to adaptive and combined therapeutic approaches. Therefore, here we review recent molecular evidence, their impact on tumor histopathological features and clinical behavior and highlight the remaining challenges to translate our cognitive corpus into patient diagnosis and allocation to therapeutic options.展开更多
Landslide hazard and risk assessment on the northern slope of Mt. Changbai, a well-known tourist attraction near the North Korean-Chinese border, are assessed. This study is divided into two parts, namely, landslide h...Landslide hazard and risk assessment on the northern slope of Mt. Changbai, a well-known tourist attraction near the North Korean-Chinese border, are assessed. This study is divided into two parts, namely, landslide hazard zonation and risk assessment. The 1992 Anbalagan and Singh method of landslide hazard zonation (LHZ) was modified and used in this area. In this way, an Associative Analysis Method was used in representative areas to get a measure for controlling factors (slope gradient, relative relief, vegetation, geology, discontinuity development, weak layer thickness and ground water). For the membership degree of factor to slope failure, the middle range of limited values was used to calculate LHZ. Based on an estimation of the potential damage from slope failure, a reasonable risk assessment map was obtained using the relationship of potential damage and probable hazard to aid future planning and prediction and to avert loss of life.展开更多
Based on field survey located by GPS, it is obtained landslides' location and distribution information by the method of remote sensing in this paper. The vector data of environmental factors that breed and induce lan...Based on field survey located by GPS, it is obtained landslides' location and distribution information by the method of remote sensing in this paper. The vector data of environmental factors that breed and induce landslides such as the elevation, the slope, the vegetation cover, the lithology, the rainfall and so on are gained using GIS(geographical information system) techniques of spatial analysis. All the data obtained are managed through building landslide management system. At the same time, the system is made the platform to appraise the relationship between the distribution of landslides and the environmental factors. The results indicate: landslides take place relatively easily in the slope range between 10° and 25°; most landslides are in the mixed area of bush and grass with a coverage degree of from 20° to 65°; the distribution of landslides has a positive relationship with the distribution of annual rainfall. The risk degree of Panxi Area is zoned and mapped by the model of liner stack using GIS technique, and the result indicates: the place of high risk degree is the belt of Panzhihua-Miyi-Dechang-Mugu and southeast of Huili county and Huidong county,and area is about 512 707 hm^2.展开更多
基金This study was supported by the National Natural Science Foundation of China under contract No. 49671071.
文摘Through densified surface sampling of foraminifera and accurate elevation measurement a-long three transect lines in open-coast tidal salt-marsh of Jianchuan, particular salt-marsh foraminifera assemblages were found. The salt-marsh foraminifera assemblages are distributed in well-defined vertical zonations with respect to elevation and closely parallel marsh floral zonations. At the top of the vertical zonation all foraminifera disappear abruptly which are accurately located at the highest high water datum. This distribution pattern can be used to relocate former sea levels accurately (to an accuracy of within ±5 cm). A modern regional criterion of foraminifera for relocating the former sea levels in high resolution in our country is provided, and deficiencies of studying the vertical zonation only in sheltered coast salt-marsh abroad are filled up.
基金supported by the Key Research and Development Program of Jilin Province(grant No.20230203107SF)the National Natural Science Foundation of China(Grant No.41790453)+1 种基金the National Key Research and Development Program of China(Grant No.2019YFC0605402)the National Major Science and Technology Project of the Ministry of Science and Technology of China(Grant No.2016ZX05026-004-001).
文摘Weathering crust reservoirs have obvious vertical zonation,which is the focus of weathering crust reservoir research,but there is a lack of quantitative characterization indexes.To achieve the quantitative characterization of granite weathering crust reservoir and provide the basis for oil exploration of granite weathering crust buried hill reservoir,in this paper,the vertical zonation of granite weathering crust reservoir is quantitatively divided by testing and analyzing the uniaxial compressive strength(UCS),magnetic susceptibility(MS),permeability,and chemical index of alteration(CIA)of the Mesozoic granite weathering crust in the coastal area of eastern Fujian.The results show that the granite weathering crust reservoir can be divided into four zones vertically:a soil zone(SZ),weathered and dissolved zone(WDZ),fracture zone(FZ),and bedrock zone(BZ).A cataclastic area is developed in the FZ and BZ,in which structural fractures are well-developed,the fracture surface density is usually greater than 200 m/m^(2),and the contribution to the fractures in the rock mass is up to about 50%,making this the sweet spot of the reservoir.In the SZ,the rocks are loose,and the pores are well-developed.The UCS is less than 10 MPa,and the average rate of change of the UCS(Δ_(σ))is 0.90.The average permeability is 2823.00 mD,and the average rate of change of the permeability(Δ_(κ))is 5.13.The average CIA is 74.9%.The average clay mineral content is 7%.The rocks in the WDZ have been significantly weathered by physical and chemical processes,and the weathering fractures and dissolution pores are well-developed.The average UCS is 18.2 MPa,and the averageΔ_(σ)is 0.70.The average permeability is 143.80 mD,and averageΔ_(κ)is 4.17.The average CIA is 65.3%.The average clay mineral content is 4%.Under the influence of tectonic movement and physical weathering,the rocks in the FZ have developed structural fractures and a few weathered fractures.The average UCS is 57.9 MPa,and the averageΔ_(σ)is 0.18.The average permeability is 5.50 mD,and the averageΔ_(κ)is 2.55.The average CIA is 61.6%.The average clay mineral content is 2%.In the BZ,the rocks are intact and hard.The average UCS is 69.9 MPa,and the average Ds is 0.13.The average permeability is 1.46 mD,and the averageΔ_(κ)is 1.43.The average CIA is 57.8%.The average clay mineral content is less than 1%.The multi-parameter combination of the UCS,Δ_(σ),permeability,Δ_(κ),CIA,and clay mineral content achieved good results in the division of the zones of the weathering crust.The UCS increases gradually from top to bottom,while Ds,permeability,Δ_(κ),CIA,and clay mineral content all decrease gradually.In addition,based on the petrophysical parameters of the rocks,including the density,resistivity,and acoustic velocity,a good division effect was also achieved,which can provide a basis for the vertical zonation of the granite buried-hill weathering crust reservoir.
基金Natural Science Foundation of Hainan Province (No.821RC682)。
文摘Parkinson's disease(PD)is a chronic progressive neurodegenerative disease.Deep brain stimulation(DBS)is an effective treatment for patients with advanced PD.There are many DBS targets for PD,including subthalamic nucleus(STN),globus pallidus(GPi),meso-ventral thalamic nucleus(VIM),pontine peduncle nucleus(PPN),posterior subthalamic region(PSA)and zonation of undetermined zone(ZI).This paper summarizes the efficacy of each target in the treatment of PD with DBS,not only makes a systematic analysis and comparison of motor symptoms,but also makes a detailed description of the efficacy of non-motor symptoms,so as to provide a personalized treatment basis for PD patients to select appropriate target targets in DBS.
基金This study was supported by the National Natural Science Foundation of China(Grants 4037200140072007+3 种基金49772083 to Dong Xiping)by the Laboratory of Paleobiology and Stratigraphy,Nanjing Institute of Geology and Palaeontology,Chinese Academy of Sciences(Grant 023106 to Dong Xiping)by the Research Fund for Doctoral Program of High Education(Grant 2000000127 to Dong Xiping)by a travel grant from the Ohio State University(to Stig M.Bergstrom).
文摘Since 1985, samples with a total weight of more than 14,000 kg, mainly from three key sections in western and northwestern Hunan, South China, have been processed for conodonts. In strata older than the late Late Cambrian paraconodonts have proved useful for stratigraphic subdivision and correlation. Thirteen conodont zones are proposed in the Middle Cambrian through lowermost Ordovician. The correlation between these zones and those of North China, western U. S.A., western Newfoundland, Canada, and Iran is discussed. In ascending order, these 13 zones are as follows: The Gapparodus bisulcatus-Westergaardodina brevidens Zone, Shandongodus priscus-Hunanognathus tricuspidatus Zone, Westergaardodina quadrata Zone, Westergaardodina matsushitai-W. grandidens Zone, Westergaardodina lui-W. am Zone, Westergaardodina cf. calix-Prooneotodus rotundatus Zone, Proconodontus tenuiserratus Zone, Proconodontus Zone, Eoconodontus Zone, Cordylodus proavus Zone, Cordylodus intermedius Zone, Cordylodus lindstromi Zone, and Cordylodus angulatus Zone (lower part). The Westergaardodina lui-W. ani and Westergaardodina cf. calix-Prooneotodus rotundatus Zones replace the Westergaardodina proligula and Westergaardodina cf. behrae-Prooneotodus rotundatus Zones, respectively, in the lowermost Upper Cambrian. Two new species (Westergaardodina Iui and Westergaardodina ani) and one conditionally identified species (Westergaardodina cf. calix) are described.
文摘Forest fire is a major cause of changes in forest structure and function. Among various floristic regions, the northeast region of India suffers maximum from the fires due to age-old practice of shifting cultivation and spread of fires from jhum fields. For proper mitigation and management, an early warning of forest fires through risk modeling is required. The study results demonstrate the potential use of remote sensing and Geographic Information System (GIS) in identifying forest fire prone areas in Manipur, southeastern part of Northeast India. Land use land cover (LULC), vegetation type, Digital elevation model (DEM), slope, aspect and proximity to roads and settlements, factors that influence the behavior of fire, were used to model the forest fire risk zones. Each class of the layers was given weight according to their fire inducing capability and their sensitivity to fire. Weighted sum modeling and ISODATA clustering was used to classify the fire zones. TO validate the results, Along Track Scanning Radiometer (ATSR), the historical fire hotspots data was used to check the occurrence points and modeled forest fire locations. The forest risk zone map has 55-63% of agreement with ATSR dataset.
基金support from:National Natural Science Foundation of China (Grant no.40672143,40472107,40172076)National Major Fundamental Research and Development Project (Grant no.2005CB422107,G1999043305)+1 种基金Development Foundation of Key Laboratory for Hydrocarbon Accumulation of Education Ministry (Grant no.2003-01)Project of Southern Exploration and Development Division Company,SINOPEC (2003-04).
文摘Field investigation and seismic section explanation showed that the Longmen Mountain Thrust Belt has obvious differential deformation: zonation, segmentation and stratification. Zonation means that, from NW to NE, the Longmen Mountain Thrust Belt can be divided into the Songpan- Garz~ Tectonic Belt, ductile deformation belt, base involved thrust belt, frontal fold-thrust belt, and foreland depression. Segmentation means that it can be divided into five segments from north to south: the northern segment, the Anxian Transfer Zone, the center segment, the Guanxian Transfer Zone and the southern segment. Stratification means that the detachment layers partition the structural styles in profile. The detachment layers in the Longmen Mountain Thrust Belt can be classified into three categories: the deep-level detachment layers, including the crust-mantle system detachment layer, intracrustal detachment layer, and Presinian system basal detachment layer; the middle-level detachment layers, including Cambrian-Ordovician detachment layer, Silurian detachment layer, etc.; and shallow-level detachment layers, including Upper Triassic Xujiahe Formation detachment layer and the Jurassic detachment layers. The multi-level detachment layers have a very important effect on the shaping and evolution of Longmen Mountain Thrust Belt.
基金Supported by the Special Project of Chinese Academy of sciences for Mountain Hazards: Debris Flow and Landslide and Oriented Project of Knowledge Innovation of Chinese Academy of sciences(KZCX2-SW-319)
文摘Through the field survey, previous researches and interpretation of aerial photos, a landslide information database of Xiaojiang Valley, Yunnan Province was set up based on the remote sensing (RS) and geographic information system (GIS) technologies. In the paper, a quantitative model for the landslide hazard assessment and zoning was presented, in which the potential energy could be obtained on basis of thorough analysis of the potential sliding volume, distance and direction of the landslide body. Taking landslide potential energy as the index of the hazard severity zonation, the study area was divided into severe, heavy, medium and light hazard zones.
基金supported by the National High Technology Research and Development Program of China (No 2006AA06Z113)the National Natural Science Foundation of China (No. 40772197)
文摘The Pulang (普朗) porphyry copper deposit, located in the southern segment of the Yidun-Zhongdian (义敦-中甸) island arc ore-forming belt of the Tethys-Himalaya ore-forming domain, is a recently discovered large copper deposit. Compared with the composition of granodiorite in China, the porphyry rocks in this area are enriched in W, Mo, Cu, Au, As, Sb, F, V, and Na2O (K1≥1.2). Compared with the composition of fresh porphyry rocks in this district, the mineralized rocks are enriched in Cu, Au, Ag, Mo, Pb, Zn, W, As, Sb, and K2O (K2≥1.2). Some elements show clear anomalies, such as Zn, Ag, Cu, Au, W, and Mo, and can be regarded as pathfinders for prospecting new ore bodies in depth. It has been inferred from factor analysis that the Pulang porphyry copper deposit may have undergone the multiple stages of alteration and mineralization: (a) Cu-Au mineralization; (b) W-Mo mineralization; and (c) silicification and potassic metasomatism in the whole ore-forming process. A detailed zonation sequence of indicator elements is obtained using the variability index of indicator elements as follows: Zn→Ag→Cu→Au→W→Mo. According to this zonation, an index such as (Ag*Zn)D/(Mo×W)D can be constructed and regarded as a significant criterion for predicting the Cu potential at a particular depth.
基金National Natural Science Foundation of China, No.40371018
文摘This paper explores the methodology for compiling the torrent hazard and risk zonation map by means of GIS technique for the Red River Basin in Yunnan province of China, where is prone to torrent. Based on a 1:250,000 scale digital map, six factors including slope angle, rainstorm days, buffer of river channels, maximum runoff discharge of standard area, debris flow distribution density and flood disaster history were analyzed and superimposed to create the torrent risk evaluation map. Population density, farmland percentage, house property, and GDP as indexes accounting for torrent hazards were analyzed in terms of vulnerability mapping. Torrent risk zonation by means of GIS was overlaid on the two data layers of hazard and vulnerability. Then each grid unit with a resolution of 500 m- 500 m was divided into four categories of the risk: extremely high, high, moderate and low. Finally the same level risk was combined into a confirmed zone, which represents torrent risk of the study area. The risk evaluation result in the upper Red River Basin shows that the extremely high risk area of 13,150 km^2 takes up 17.9% of the total inundated area, the high risk area of 33,783 km^2 is 45.9%, the moderate risk area of 18,563 km^2 is 25.2% and the low risk area of 8115 km^2 is 11.0%.
基金The National Natural Science Foundation of China No. 4987102049801003 and 49890330-4-2The Scientific Department of Hebei Province No. 01220703D
文摘The groundwater table has been declining at a rate of 0.65 m/yr in Luancheng County since large scale groundwater extraction carried out in the 1960s. The drop of precipitation, substantial increase in agricultural output, variations of crop planting structure and construction of water conservancy projects in the headwater area all tie up with the decline of the groundwater table. On the basis of analyzing the hydrogeological conditions and the water resources utilization of Luancheng County, a three-dimensional groundwater flow model was developed to simulate the county抯 groundwater flow through finite-difference method using Visual Modflow software. We divide the research field into four parts after analyzing the hydrogeological condition. Based on parameter calibration and adjustment using measured data, the hydraulic conductivity and specific yield were simulated. Using the calibrated model, we analyze the agricultural water saving potentiality and its influence on the groundwater. The results are as follows: (1) if we decrease the amount of water extracted by 0.14×108 m3, the average groundwater table of the five observation wells in December will rise by 0.33 m; (2) if we decrease the water by 0.29×108 m3, the average groundwater table of the five observation wells in December will rise by 0.64 m; and (3) if we increase the water by 0.29×108 m3, the average groundwater table of the five observation wells in December will decline by 0.45 m. So we can draw a conclusion that controlling the agricultural water use is an important way to prevent the decline of groundwater table.
基金Supported by Bundesministerium für Forschung und Technologie(BMBF)in the framework of the Systems Biology initiative"Virtual Liver Network",No.0315735
文摘Liver zonation,the spatial separation of the immense spectrum of different metabolic pathways along the liver sinusoids,is fundamental for proper functioning of this organ.Recent progress in elucidating localization and interactions of different metabolic pathways by using"omics"techniques and novel approaches to couple them with refined spatial resolution and in characterizing novel master regulators of zonation by using transgenic mice has created the basis for a deeper understanding of core mechanisms of zonation and their impact on liver physiology,pathology and metabolic diseases.This review summarizes the fascinating technical achievements for investigating liver zonation and the elucidation of an emerging network of master regulators of zonation that keep the plethora of interrelated and sometimes opposing functions of the liver in balance with nutritional supply and specific requirements of the entire body.In addition,a brief overview is given on newly described zonated functions and novel details on how diverse the segmentation of metabolic zonation may be.From these facts and developments a few fundamental principles are inferred which seem to rule zonation of liver parenchyma.In addition,we identify important questions that still need to be answered as well as interesting fields of research such as the connection of zonation with circadian rhythm and gender dimorphism which need to be pushed further,in order to improve our understanding of metabolic zonation.Finally,an outlook is given on how disturbance of liver zonation and its regulation may impact on liver pathology and the development of metabolic diseases.
基金funded by the National Natural Science Foundation of China under contract Nos 30470343,30300050 and 39830060the Guangdong Natural Science Foundation under contract No.04010990.
文摘Intertidal marine macroalgae experience periodical exposures during low tide due to their zonational distribution. The duration of such emersion leads to different exposures of the plants to light and aerial CO2, which then affect the physiology of them to different extents. The ecophysiological responses to light and CO2 were investigated during emersion in two red algae Gloiopeltis furcata and Gigartina intermedia, and two brown algae Petalonia fascia and Sargassum hemiphyllum, growing along the Shantou coast of China. The light-saturated net photosynthesis in G. furcata and P. fascia showed an increase followed by slightly desiccation, whereas that in G. intermedia and S. hemiphyllumexhibited a continuous decrease with water loss. In addition, the upper-zonated G. furcata and P. fascia, exhibited higher photosynthetic tolerance to desiccation and required higher light level to saturate their photosynthesis than the lower-zonated G. intermedia and S. hemiphyllum. Desiccation had less effect on dark respiration in these four algae compared with photosynthesis. The light-saturated net photosynthesis increased with increased CO2 concentrations, being saturated at CO2 concentrations higher than the present atmospheric level in G. furcata, G. intermedia and S. hemiphyllum during emersion. It was evident that the relative enhancement of photosynthesis by elevated CO2 in those three algae increased, though the absolute values of photosynthetic enhancement owing to CO2 increase were reduced when the desiccation statuses became more severe. However, in the case of desiccated P. fascia (water loss being greater than 20 %), light saturated net photosynthesis was saturated with current ambient atmospheric CO2 level. It is proposed that increasing atmospheric CO2 will enhance the daily photosynthetic production in intertidal macroalgae by varied extents that were related to the species and zonation.
文摘Mineralogical zonation of wall rock alterations in Mesozoic granitoids is summarized from 18 gold deposits in Jiaodong gold province on the Asian mobile continental margin of the west circum Pacific rim. This paper deals with wall rock alterations developed around gold mineralizations of the quartz vein type in granitoids and the wall rock alteration type in granitoid basement contacts along Mesozoic fault zones trending mostly NNE SSW and NE SW. Five alteration zones are distinguished from host rock to ore zone, namely the chloritization and sericitization zone, the hematitization rutilization and microclinization zone, the quartz sericitization zone, the pyrite quartz sericitization zone and the pyrite silicification zone. The former two are outer zones marked by incomplete alteration of first mafic and then felsic minerals of the granitoids, while the later three are inner zones marked by complete alteration of both mafic and felsic minerals of the granitoids leading to retrogressive sericitization and progressive silicification with participation of ore elements. The whole process proceeds under dynamometamorphism with high fugacity of volatiles. Wall rock alteration is the intermediate link between unaltered host rock and ore mineralization both in time and space. Development of the alteration zonation and its mineral composition controls genetic type of mineralization, size and grade of the deposit and location of the ore zones.
基金Supported by INSERM(to Musso O)United States Department of Defense Office of the Congressionally Directed Medical Research Programs Grant,No.CA170172(to Nieto N and Désert R)
文摘Hepatocellular carcinoma(HCC) is the 3^(rd) leading cause of cancer-related death worldwide. More than 80% of HCCs arise within chronic liver disease resulting from viral hepatitis, alcohol, hemochromatosis, obesity and metabolic syndrome or genotoxins. Projections based on Western lifestyle and its metabolic consequences anticipate a further increase in incidence, despite recent breakthroughs in the management of viral hepatitis. HCCs display high heterogeneity of molecular phenotypes, which challenges clinical management. However, emerging molecular classifications of HCCs have not yet formed a unified corpus translatable to the clinical practice. Thus, patient management is currently based upon tumor number, size, vascular invasion, performance status and functional liver reserve. Nonetheless, an impressive body of molecular evidence emerged within the last 20 years and is becoming increasingly available to medical practitioners and researchers in the form of repositories. Therefore, the aim this work is to review molecular data underlying HCC classifications and to organize this corpus into the major dimensions explaining HCC phenotypic diversity. Major efforts have been recently made worldwide toward a unifying "clinically-friendly" molecular landscape. As a result, a consensus emerges on three major dimensions explaining the HCC heterogeneity. In the first dimension, tumor cell proliferation and differentiation enabled allocation of HCCs to two major classes presenting profoundly different clinical aggressiveness. In the second dimension, HCC microenvironment and tumor immunity underlie recent therapeutic breakthroughs prolonging patients' survival. In the third dimension,metabolic reprogramming, with the recent emergence of subclass-specific metabolic profiles, may lead to adaptive and combined therapeutic approaches. Therefore, here we review recent molecular evidence, their impact on tumor histopathological features and clinical behavior and highlight the remaining challenges to translate our cognitive corpus into patient diagnosis and allocation to therapeutic options.
文摘Landslide hazard and risk assessment on the northern slope of Mt. Changbai, a well-known tourist attraction near the North Korean-Chinese border, are assessed. This study is divided into two parts, namely, landslide hazard zonation and risk assessment. The 1992 Anbalagan and Singh method of landslide hazard zonation (LHZ) was modified and used in this area. In this way, an Associative Analysis Method was used in representative areas to get a measure for controlling factors (slope gradient, relative relief, vegetation, geology, discontinuity development, weak layer thickness and ground water). For the membership degree of factor to slope failure, the middle range of limited values was used to calculate LHZ. Based on an estimation of the potential damage from slope failure, a reasonable risk assessment map was obtained using the relationship of potential damage and probable hazard to aid future planning and prediction and to avert loss of life.
文摘Based on field survey located by GPS, it is obtained landslides' location and distribution information by the method of remote sensing in this paper. The vector data of environmental factors that breed and induce landslides such as the elevation, the slope, the vegetation cover, the lithology, the rainfall and so on are gained using GIS(geographical information system) techniques of spatial analysis. All the data obtained are managed through building landslide management system. At the same time, the system is made the platform to appraise the relationship between the distribution of landslides and the environmental factors. The results indicate: landslides take place relatively easily in the slope range between 10° and 25°; most landslides are in the mixed area of bush and grass with a coverage degree of from 20° to 65°; the distribution of landslides has a positive relationship with the distribution of annual rainfall. The risk degree of Panxi Area is zoned and mapped by the model of liner stack using GIS technique, and the result indicates: the place of high risk degree is the belt of Panzhihua-Miyi-Dechang-Mugu and southeast of Huili county and Huidong county,and area is about 512 707 hm^2.