Progress and prospects of acupuncture research on the mechanism of post-stroke depression

The articles on the pathogenesis of post-stroke depression(PSD)and the acupuncture treatment mechanism of PSD from January 2010 through to June 2020 were retrieved from China National knowledge Infrastructure(CNKI),Wanfang Database,VIP China Science-Technology and National Social Sciences Database.In summary,the potential mechanism of acupuncture in treatment of PSD is explained from the following three aspects:acupuncture regulating monoamine neurotransmitters,acupuncture regulating neurotrophic factors and acupuncture regulating cytokines.The limitation and prospects of the current researches are also put forward so as to provide the references and to determine the research direction in the future.

Experience and Thinking on Study of Pneumonectomy by Acupuncture Anesthesia

Acupuncture anesthesia is a great breakthrough in the development history of acupuncture science in China. It has promoted the development of acupuncture science, promoted the study on acupuncture from multiple subjects of modem natural sciences and has become an important component part in the studies of modem life scienceIll. Pneumonectomy under acupuncture anesthesia is an important component part of the research outcomes in acupuncture anesthesia, and the research professionals of Shanghai Lung Hospital and Shanghai Research Institute of Acupuncture and Meridians used to cooperate in the study of pneumonectomy under acupuncture anesthesia and to be in the leading position domestically. This article reviews the research process of pneumonectomy under acupuncture anesthesia, analyzes the issues existing in the study and the difficult points needed to be solved and explores the solving measures and research orientation.

Acupuncture for acute gastrointestinal injury:A systematic review and meta-analysis

Objective:To systematically review the clinical therapeutic effect of acupuncture on acute gastrointestinal injury(AGI)in critically ill patients.Methods:The randomized control trials of acupuncture for AGI in critically ill patients were retrieved from the databases,from inception to the cutoff date in August,2021,including China National Knowledge Infrastructure(CNKI),Wanfang,VIP,China Biology Medicine disc(CBM),PubMed,Science Direct and Cochrane Library.Simultaneously,the accomplished and published RCTs were further searched from American clinical trial registry platform(https://clinicaltrials.gov)and Chinese clinical trial registry platform(www.chictr.org.cn).Two researchers extracted the data and performed the quality evaluation of the eligible articles independently.The meta-analysis was undertaken,by using RevMan 5.4.Results:Totally,15 papers were included,involving 1316 patients.The results of meta-analysis showed that after treated with acupuncture,the differences were statistical significance as compared with the routine treatment group in the score of the second edition of Acute Physiology and Chronic Health Evaluation(APACHEII)(MD=-1.98,95%CI[-3.23,-0.73],P=0.002),gastrointestinal dysfunction score(MD=-0.33,95%CI[-0.41,-0.24],P<0.00001),the intra-abdominal pressure(mmHg)(MD=-2.74,95%CI[-3.81,-1.67],P<0.00001),intensive care unit(ICU)length of stay(MD=-3.15,95%CI[-5.99,-0.30],P<0.00001)and fatality rate in 28-day(RR=0.57,95%CI[0.39,0.85],P=0.006)in critically ill patients with AGI,respectively.Conclusion:The limited available evidence suggests that acupuncture relieves clinical symptoms and poor prognosis in the critically ill patients with AGI,thus,it is one of the potential therapies to AGI.Hence,acupuncture should be recommended into the regimen of AGI in critically ill patients and more highquality and multi-central trials can be undertaken in the further.

Analysis on the key factors of allergic rhinitis treated with acupuncture and moxibustion

Allergic rhinitis(AR)is the frequently-encountered disease and commonly seen in clinic.Acupuncturemoxibustion therapy brings the significant therapeutic effects on it.In order to achieve the significant effects on AR,the relevant key factors should be determined definitely in treatment with acupuncturemoxibustion therapy.In the combination of the theoretic study with clinical practice,the authors expounded the key factors in acupuncture-moxibustion treatment for AR,including the identification of disease and syndrome of traditional Chinese medicine(TCM),the differentiation of meridians,acupoint selection,manipulation key factors and timing.Moreover,the authors proposed a new pointcut for the future clinical research,aiming to further optimize the therapeutic regimen of acupuncture and moxibusiton for AR.

Objective Tongue Inspection on 142 Liver Cancer Patients with Damp-Heat Syndrome

Objective： To establish the diagnosis evidence of objective tongue inspection for liver cancer （LC） patients with damp-heat syndrome （DHS） by dynamically observing their tongue figures using modern tongue image analytic apparatus, and to explore the effect of intervention on the tongue figures. Methods： Tongue figures were collected from 142 LC patients with DHS by tongue image analytic apparatus. Red （R）, green （G） and blue （B） values were analyzed. The r and g values were calculated requesting r=R/（R＋G＋B）, g=G/（R＋G＋B）, and b=l-r-g, and scored in combination with Chinese medical symptoms scale. The tongue figure and correlated scores were collected from 59 of them 3 days after transcatheter arterial chemoembolization intervention. Results： The range of objective tongue inspection of LC patients with DHS was as follows： as for tongue fur, 0.360〈r〈0.402 and 0.280〈g〈0.322; as for tongue proper, 0.404〈r〈0.470 and 0.243〈g〈0.301. The tongue figures and the average scores of quality of life, DHS, poor appetite, aggravated pain, decreased sleep quality and aggravated fever were obviously changed in the 59 LC patients with DHS after intervention, showing statistical difference when compared with before intervention （P〈0.05 or P〈0.01）. Conclusion： The range of objective tongue inspection of LC patients with DHS could be known by collecting and analyzing objective indicator of tongue figures, thus laying foundation for further studies with analysis of correlation between intervention and Chinese medicine based on tongue figures.

Prof. Gui-rong DONG's experience in treatment of prurigo nodularis with acupuncture

The patient with prurigo nodularis were treated by needling at Bǎihuì（百会 GV 20）, Fēngchi（风池 GB 20）,Fēngfǔ（风府 GV 16）, Dàzhuī（大椎 GV 14）,Fēngmén（风门 BL 12）, Xīnshù（心俞 BL 15）, Gānshù（肝俞 BL18）, Qìhǎi（气海 CV 6）,Guānyuán（关元 CV 4）, Zhōngwǎn（中脘 CV12）, Xuèhǎi（血海 SP 10）, Zúsānlǐ（足三里ST 36）, Sānyīnjiāo（三阴交 SP 6）, Nèiting（内庭 ST 44）,Qūchí（曲池 LI 11）, Wàiguān（外关 TE 5） and Hégǔ（合谷 LI 4）. The treatment was given 4 times a week. After 2 weeks of treatment, the subjective pruritus was alleviated and tolerable. The patients could fall into sleep. After 2 months of treatment, no new skin rashes appear and pruritus disappeared basically, the old rashes started fading. The red color was getting pale and the bumpy rashes were absorbed. After 5 months of treatment, the itching symptoms were gone and skin rashes disappeared basically. The lesion skin was pigmented in dark grey. After 6 months of treatment, the dark grey pigmentation disappeared and skin was normal in color. The disease was not recurred in 1 year of follow-up.

Application of intelligent rehabilitation equipment in occupational therapy for enhancing upper limb function of patients in the whole phase of stroke

Stroke was one of the leading causes of death in the Chinese population in 2017.Most stroke survivors may suffer from different levels of disabilities,which prevents them from returning to their daily activities.The decreased upper limb function is considered as the principal factor that makes the patients have less access to their activities of daily livings.Occupational therapy(OT),aiming to enhance patients'functional performances and improve the participation in daily activities is usually applied from the onset of stroke.However,conventional OT intervention still has several problems that need to be solved,such as the inefficient use of human resources,inadequate upper limb functional training and non-continuous OT services.To address these difficulties and improve the patients'functional outcomes,intelligent rehabilitation equipment is combined with OT through evaluation and intervention.Based on this combination,OT can be provided in health care facilities,home,and community for patients with all phases of stroke.This combination promotes the transition of OT to digitization,intelligence and homogenization.