邻氨基苯甲酸(Anthranilic acid, ATA)是微生物产生的一种小分子化合物,是色氨酸合成途径的中间产物。近年来一些研究发现ATA是一类信号分子,影响微生物生理功能。本文首先概述了大肠杆菌和酿酒酵母中ATA与色氨酸合成的关系,随后详细介...邻氨基苯甲酸(Anthranilic acid, ATA)是微生物产生的一种小分子化合物,是色氨酸合成途径的中间产物。近年来一些研究发现ATA是一类信号分子,影响微生物生理功能。本文首先概述了大肠杆菌和酿酒酵母中ATA与色氨酸合成的关系,随后详细介绍了ATA在铜绿假单胞菌中的代谢与功能,以及ATA调控青枯雷尔氏菌的生理活动。最后结合其他微生物中ATA的最新研究结果,我们提出ATA可能参与微生物跨界交流。Anthranilic acid (ATA) is a small molecule produced by microorganisms and is an intermediate product of the tryptophan synthesis pathway. In recent years, it has been revealed that ATA is a new signaling molecule and has effects on microbial physiology. In this review, we first briefly outlined the relationship between ATA and tryptophan synthesis in Escherichia coli and Saccharomyces cerevisiae. We then summarized the metabolic network and biological functions of ATA in Pseudomonas aeruginosa, as well as the progress of ATA in regulating the physiology of Ralstonia solanacearum. Finally, we summarized the latest results describing the roles of ATA in other microorganisms and proposed that ATA may play a role in interkingdom communication.展开更多
茉莉酸是一种重要的植物激素,在植物生长发育和防御响应过程中发挥重要的调节作用。最新研究表明,在病原微生物–植物宿主互作过程中,病原微生物的侵染可以激活植物宿主体内由茉莉酸介导的防御响应。同时病原微生物可以感应茉莉酸信号,...茉莉酸是一种重要的植物激素,在植物生长发育和防御响应过程中发挥重要的调节作用。最新研究表明,在病原微生物–植物宿主互作过程中,病原微生物的侵染可以激活植物宿主体内由茉莉酸介导的防御响应。同时病原微生物可以感应茉莉酸信号,通过多种机制操纵植物宿主茉莉酸信号传导途径,增强自身侵染能力,提高致病性。本文首先简述茉莉酸的生物合成途径与信号传导机制,随后介绍茉莉酸在病原细菌、真菌及病毒与植物宿主相互作用过程中的多重作用。这些研究结果有助于系统深入理解病原微生物与植物宿主互作中茉莉酸的多重功能。Jasmonic acid is an important plant hormone that plays a crucial regulatory role in plant growth, development, and defence responses. Latest results indicate that the invasion of pathogenic microorganisms can activate the jasmonic acid defense mechanism of plant hosts. At the same time, pathogenic microorganisms can sense jasmonic acid and manipulate the jasmonic acid signal transduction pathways of plant hosts, thus enhancing their own pathogenicity. In this review, we first briefly describe the biosynthesis and signalling pathways of jasmonic acid, followed by an overview of the research progress on the multiple functions of jasmonic acid in the interaction of various pathogenic bacteria, fungi, and viruses with plant hosts. These findings will provide insights in understanding the roles of jasmonic acid in the interaction between pathogenic microorganisms and plant hosts.展开更多
文摘邻氨基苯甲酸(Anthranilic acid, ATA)是微生物产生的一种小分子化合物,是色氨酸合成途径的中间产物。近年来一些研究发现ATA是一类信号分子,影响微生物生理功能。本文首先概述了大肠杆菌和酿酒酵母中ATA与色氨酸合成的关系,随后详细介绍了ATA在铜绿假单胞菌中的代谢与功能,以及ATA调控青枯雷尔氏菌的生理活动。最后结合其他微生物中ATA的最新研究结果,我们提出ATA可能参与微生物跨界交流。Anthranilic acid (ATA) is a small molecule produced by microorganisms and is an intermediate product of the tryptophan synthesis pathway. In recent years, it has been revealed that ATA is a new signaling molecule and has effects on microbial physiology. In this review, we first briefly outlined the relationship between ATA and tryptophan synthesis in Escherichia coli and Saccharomyces cerevisiae. We then summarized the metabolic network and biological functions of ATA in Pseudomonas aeruginosa, as well as the progress of ATA in regulating the physiology of Ralstonia solanacearum. Finally, we summarized the latest results describing the roles of ATA in other microorganisms and proposed that ATA may play a role in interkingdom communication.
文摘茉莉酸是一种重要的植物激素,在植物生长发育和防御响应过程中发挥重要的调节作用。最新研究表明,在病原微生物–植物宿主互作过程中,病原微生物的侵染可以激活植物宿主体内由茉莉酸介导的防御响应。同时病原微生物可以感应茉莉酸信号,通过多种机制操纵植物宿主茉莉酸信号传导途径,增强自身侵染能力,提高致病性。本文首先简述茉莉酸的生物合成途径与信号传导机制,随后介绍茉莉酸在病原细菌、真菌及病毒与植物宿主相互作用过程中的多重作用。这些研究结果有助于系统深入理解病原微生物与植物宿主互作中茉莉酸的多重功能。Jasmonic acid is an important plant hormone that plays a crucial regulatory role in plant growth, development, and defence responses. Latest results indicate that the invasion of pathogenic microorganisms can activate the jasmonic acid defense mechanism of plant hosts. At the same time, pathogenic microorganisms can sense jasmonic acid and manipulate the jasmonic acid signal transduction pathways of plant hosts, thus enhancing their own pathogenicity. In this review, we first briefly describe the biosynthesis and signalling pathways of jasmonic acid, followed by an overview of the research progress on the multiple functions of jasmonic acid in the interaction of various pathogenic bacteria, fungi, and viruses with plant hosts. These findings will provide insights in understanding the roles of jasmonic acid in the interaction between pathogenic microorganisms and plant hosts.
