Cardiac extracellular matrix undergoes extensive and continuous turnover involved in the lesion reparation process, such as in cardiac remodeling, in hypertensive cardiac hypertrophy, in dilated cardiomyopathy, after ...Cardiac extracellular matrix undergoes extensive and continuous turnover involved in the lesion reparation process, such as in cardiac remodeling, in hypertensive cardiac hypertrophy, in dilated cardiomyopathy, after myocardial infarction in the transition to heart failure, and during the progression of left ventricular dysfunction. This report discusses most recent experimental findings and focuses on the alterations in nonmyocytic elements that are a part of heart involvement. Particular attention was given to factors that are responsible for exaggerated myocardial deposition of collagen that may be responsible for ventricular dysfunction.展开更多
慢性完全闭塞（chronic total occlusion，CTO）病变通常被认为是冠心病经皮冠状动脉介入治疗（PCI）中“最后待以攻克的堡垒”。近年来随着手术器械的不断改进、术者经验和技术的提高，尤其是逆向导引钢丝技术的应用，使CTO-PCI的手术...慢性完全闭塞（chronic total occlusion，CTO）病变通常被认为是冠心病经皮冠状动脉介入治疗（PCI）中“最后待以攻克的堡垒”。近年来随着手术器械的不断改进、术者经验和技术的提高，尤其是逆向导引钢丝技术的应用，使CTO-PCI的手术成功率得以显著提高[1-4]。本文将结合中国国情，从实战角度对逆向导引钢丝技术在CTO-PCI中的应用做一论述。展开更多
文摘Cardiac extracellular matrix undergoes extensive and continuous turnover involved in the lesion reparation process, such as in cardiac remodeling, in hypertensive cardiac hypertrophy, in dilated cardiomyopathy, after myocardial infarction in the transition to heart failure, and during the progression of left ventricular dysfunction. This report discusses most recent experimental findings and focuses on the alterations in nonmyocytic elements that are a part of heart involvement. Particular attention was given to factors that are responsible for exaggerated myocardial deposition of collagen that may be responsible for ventricular dysfunction.
文摘慢性完全闭塞（chronic total occlusion，CTO）病变通常被认为是冠心病经皮冠状动脉介入治疗（PCI）中“最后待以攻克的堡垒”。近年来随着手术器械的不断改进、术者经验和技术的提高，尤其是逆向导引钢丝技术的应用，使CTO-PCI的手术成功率得以显著提高[1-4]。本文将结合中国国情，从实战角度对逆向导引钢丝技术在CTO-PCI中的应用做一论述。
