本文讨论了在随机利率作用下经典风险模型的破产问题,给出了导致公司破产的索赔额的L ap lace变换所满足的微分方程,给出了破产概率二次连续可微性的条件,得到了导致公司破产的所满足的积分微分方程;破产时刻公司赤字的L ap lace变换所...本文讨论了在随机利率作用下经典风险模型的破产问题,给出了导致公司破产的索赔额的L ap lace变换所满足的微分方程,给出了破产概率二次连续可微性的条件,得到了导致公司破产的所满足的积分微分方程;破产时刻公司赤字的L ap lace变换所满足的积分-微分方程.作为特例,本文给出了当索赔为指数分布地导致破产索赔额的L ap lace变换和破产时刻赤字的L ap lace变换的微分方程.展开更多
By comparing the entropy and the conditional entropy in a marker, an entropy-based index has been presented for fine-scale linkage disequilibrium gene mapping using high-density marker maps for human disease genes. Th...By comparing the entropy and the conditional entropy in a marker, an entropy-based index has been presented for fine-scale linkage disequilibrium gene mapping using high-density marker maps for human disease genes. The index can quantify the level of linkage disequilibrium (LD) between the marker and the disease susceptibility locus (DSL) of genes. The advantage of using the index is attributed to the fact that it does not depend on marker allele frequencies across loci. Moreover, it is parallel to Hardy-Weinberg disequilibrium (HWD) measure for DSL fine mapping. Through various simulations, the fine mapping perform- ances of the proposed entropy-based index was extensively investigated under various genetic parameters. The results show that the index presented is both robust and powerful for DSL mapping in genes.展开更多
文摘本文讨论了在随机利率作用下经典风险模型的破产问题,给出了导致公司破产的索赔额的L ap lace变换所满足的微分方程,给出了破产概率二次连续可微性的条件,得到了导致公司破产的所满足的积分微分方程;破产时刻公司赤字的L ap lace变换所满足的积分-微分方程.作为特例,本文给出了当索赔为指数分布地导致破产索赔额的L ap lace变换和破产时刻赤字的L ap lace变换的微分方程.
文摘By comparing the entropy and the conditional entropy in a marker, an entropy-based index has been presented for fine-scale linkage disequilibrium gene mapping using high-density marker maps for human disease genes. The index can quantify the level of linkage disequilibrium (LD) between the marker and the disease susceptibility locus (DSL) of genes. The advantage of using the index is attributed to the fact that it does not depend on marker allele frequencies across loci. Moreover, it is parallel to Hardy-Weinberg disequilibrium (HWD) measure for DSL fine mapping. Through various simulations, the fine mapping perform- ances of the proposed entropy-based index was extensively investigated under various genetic parameters. The results show that the index presented is both robust and powerful for DSL mapping in genes.