方法对150名年龄自11～18岁的男性儿童和青少年进行24 h 动态血压监测(ABP)。结果 142例分为11～12岁,13～15岁,16～18岁3个年龄组。ABP(mmHg)第95百分位数分别为:115/65,120/69,124/76;24 h ABP 的上限为:110/63, 115/66,121/69;白天...方法对150名年龄自11～18岁的男性儿童和青少年进行24 h 动态血压监测(ABP)。结果 142例分为11～12岁,13～15岁,16～18岁3个年龄组。ABP(mmHg)第95百分位数分别为:115/65,120/69,124/76;24 h ABP 的上限为:110/63, 115/66,121/69;白天平均血压(自10AM～8PM)为:115/67,119/69,124/72;夜间平均血压(自12PM～6AM)为:105/59,109/64,115/67,ABP 低于 CBP(偶测血压);ABP 和 CBP 与年龄、身高、体重指数(BMI)正相关,各年龄组的 CBP、ABP、白天血压、夜间血压以及百分位数均随年龄和 BMI 逐渐增高;ABP的生理性周期变化与成人相似;没有发现24 h 尿电解质浓度与血压有意义的相关;有一、二级亲属患高血压病的儿童和青少年24 h ABP 显著升高。展开更多
Acute stroke is a substantial public health problem.So far,numerous treatments have been suggested for acute ischaemic stroke,but non has been shown to be effective either because few theoretical benefits have been bo...Acute stroke is a substantial public health problem.So far,numerous treatments have been suggested for acute ischaemic stroke,but non has been shown to be effective either because few theoretical benefits have been born out in practice,or much more often because the clinical trials have been too small to show any treatment effect.The Chinese Large Scale Stroke Clinical Trial is a randomizedly controlled and multicentre study of the value of antiplatelet therapy in the acute phase of ischaemic stroke(within 48 hours after onset of symptoms of stroke).Its chief aim is to obtain a reliable assessment of the separate effects on mortality and on disability in survivals of antithrombotic regiments.The study is intended to recruit 20000 patients.Diagnosis of stroke is a clinical one,and exclusion of patients with TIA and intracranial hemorrhage by CT scanning before randomization should be made in comatose patients.Patients will be randomized by sealed envelops which contain random numbers,and the allocated treatment is oral aspirin 160 mg daily or placebo to be continued for four weeks or until discharge (or transfer).The trial procedures are very simple and only two forms have to be completed in four weeks after randomization.No special follow ups for the trial or special monitoring is required.The pilot study has been conducted at ten hospitals in this country since April,1993.展开更多
文摘Acute stroke is a substantial public health problem.So far,numerous treatments have been suggested for acute ischaemic stroke,but non has been shown to be effective either because few theoretical benefits have been born out in practice,or much more often because the clinical trials have been too small to show any treatment effect.The Chinese Large Scale Stroke Clinical Trial is a randomizedly controlled and multicentre study of the value of antiplatelet therapy in the acute phase of ischaemic stroke(within 48 hours after onset of symptoms of stroke).Its chief aim is to obtain a reliable assessment of the separate effects on mortality and on disability in survivals of antithrombotic regiments.The study is intended to recruit 20000 patients.Diagnosis of stroke is a clinical one,and exclusion of patients with TIA and intracranial hemorrhage by CT scanning before randomization should be made in comatose patients.Patients will be randomized by sealed envelops which contain random numbers,and the allocated treatment is oral aspirin 160 mg daily or placebo to be continued for four weeks or until discharge (or transfer).The trial procedures are very simple and only two forms have to be completed in four weeks after randomization.No special follow ups for the trial or special monitoring is required.The pilot study has been conducted at ten hospitals in this country since April,1993.
