目的:研究玄参科婆婆纳属植物水蔓菁(Veronica linariifolia Pall. ex Link subsp. dilatata(Nakai et Kitagawa)Hong)中的酚性化学成分。方法:采用75%乙醇提取,运用各种色谱方法进行化学成分的分离纯化,用理化方法及波谱手段解析其化...目的:研究玄参科婆婆纳属植物水蔓菁(Veronica linariifolia Pall. ex Link subsp. dilatata(Nakai et Kitagawa)Hong)中的酚性化学成分。方法:采用75%乙醇提取,运用各种色谱方法进行化学成分的分离纯化,用理化方法及波谱手段解析其化学结构。结果:分离并鉴定了14个酚性化合物,其中黄酮类7个,分别为3′,4′,5,6,7-五羟基黄酮-7-O-β-D-葡萄糖基-(1″→2′)-β-D-葡萄糖苷(Ⅰ)、4′,5,7-三羟基-3′,6-二甲氧基黄酮-7-O-β-D-葡萄糖苷(Ⅱ)、芹菜素-7-O-β-D-葡萄糖醛酸苷甲酯(Ⅲ)、芹菜素-7-O-β-D-葡萄糖醛酸苷乙酯(Ⅳ)、芹菜素-7-O-β-D-葡萄糖醛酸苷丁酯(Ⅴ)、芹菜素(Ⅵ)、木犀草素(Ⅶ);酚酸类5个,分别为香草酸(Ⅷ)、对羟基苯甲酸(Ⅸ)、原儿茶酸(Ⅹ)、原儿茶酸乙酯(Ⅺ)、异阿魏酸(Ⅻ),还分到儿茶酚(X)、大黄素(XⅣ)。结论:除化合物Ⅵ、Ⅶ外,其余均为在该植物中首次分得,其中化合物Ⅱ～Ⅴ、Ⅺ、X、X为该属植物中首次分得。展开更多
AIM: To investigate the chemical constituents of Iris tectorum Maxim. METHOD: The chemical constituents were isolated and purified by solvent extraction together with various chromatographic techniques. The structures...AIM: To investigate the chemical constituents of Iris tectorum Maxim. METHOD: The chemical constituents were isolated and purified by solvent extraction together with various chromatographic techniques. The structures were elucidated on the basis of chemical evidence and spectral data. RESULTS: Seven compounds were isolated from the EtOAc extracts of the rhizome of Iris tectorum Maxim.,which were apocynin (Ⅰ),rhamnocitrin (Ⅱ),tectorigenin (Ⅲ),iristectorigenin A (Ⅳ),β-sitosterol(Ⅴ),dihydrokaempferide (Ⅵ) ,irigenin(Ⅶ);seven compounds were isolated from the n-BuOH extracts,which were tectoridin (Ⅷ),androsin (Ⅸ),n-Butyl-β-D-fructopyranoside (Ⅹ),iristectorin B (Ⅺ),iridin (Ⅻ),tectorigenin-7-O-β-glucosyl-4′-O-β-glucoside (),daucosterol (■). CONCLUSION: Compound Ⅱ,Ⅵ,Ⅹ were isolated from Iris for the first time.展开更多
Derivation conditions of pre-column derivation-HPLC method used for determinating artemisinin content were compared and selected,and artemisinin content in above-ground part of Artemisia annua L.from seventeen locatio...Derivation conditions of pre-column derivation-HPLC method used for determinating artemisinin content were compared and selected,and artemisinin content in above-ground part of Artemisia annua L.from seventeen locations was compared by optimal pre-column derivation-HPLC method.The optimal derivation condition is selected via comparing of 0.2% NaOH solution addition(3,4,5,6 and 7 mL),derivation temperature(30 ℃,35 ℃,40 ℃,45 ℃ and 50 ℃) and derivation time(0,2,5,10,20,40 and 60 min) during derivation process.The optimal derivation condition is adding 5 mL 0.2% NaOH solution,then insulating in 40 ℃ water bath for 10 min.Differences of artemisinin content in A.annua from seventeen locations are obvious,the general trend is that artemisinin content decreases gradually with location from south to north,in which artemisinin content in A.annua from Youyang of Chongqing is the highest with a value of 7.08 mg·g-1.The method is simple and accurate with good reproducibility,and can be used to determinate artemisinin content in medicinal material of A.annua.展开更多
Thirteen compounds were isolated from dry above-ground part of Scutellaria barbata D.Don and their structures were identified.These compounds are p-hydroxybenzaldehyde(Ⅰ),p-coumaric acid(Ⅱ),hydroxyhydroquinone(Ⅲ),h...Thirteen compounds were isolated from dry above-ground part of Scutellaria barbata D.Don and their structures were identified.These compounds are p-hydroxybenzaldehyde(Ⅰ),p-coumaric acid(Ⅱ),hydroxyhydroquinone(Ⅲ),hispidulin(IV),5,7,4′-trihydroxy-8-methoxyflavone(Ⅴ),apigenin(Ⅵ),luteolin(Ⅶ),apigenin-5-O-β-D-glucopyranoside(Ⅷ),scutellaric acid(Ⅸ),stigmasta-5,22-dien-3-O-β-D-glucopyranoside(Ⅹ),barbatin C(Ⅺ),β-sito-sterol(Ⅻ) and daucosterol(ⅩⅢ).Compound Ⅷ is isolated from Scutellaria L.for the first time,and compound Ⅲ and compound X are isolated from S.barbata for the first time.展开更多
文摘目的:研究玄参科婆婆纳属植物水蔓菁(Veronica linariifolia Pall. ex Link subsp. dilatata(Nakai et Kitagawa)Hong)中的酚性化学成分。方法:采用75%乙醇提取,运用各种色谱方法进行化学成分的分离纯化,用理化方法及波谱手段解析其化学结构。结果:分离并鉴定了14个酚性化合物,其中黄酮类7个,分别为3′,4′,5,6,7-五羟基黄酮-7-O-β-D-葡萄糖基-(1″→2′)-β-D-葡萄糖苷(Ⅰ)、4′,5,7-三羟基-3′,6-二甲氧基黄酮-7-O-β-D-葡萄糖苷(Ⅱ)、芹菜素-7-O-β-D-葡萄糖醛酸苷甲酯(Ⅲ)、芹菜素-7-O-β-D-葡萄糖醛酸苷乙酯(Ⅳ)、芹菜素-7-O-β-D-葡萄糖醛酸苷丁酯(Ⅴ)、芹菜素(Ⅵ)、木犀草素(Ⅶ);酚酸类5个,分别为香草酸(Ⅷ)、对羟基苯甲酸(Ⅸ)、原儿茶酸(Ⅹ)、原儿茶酸乙酯(Ⅺ)、异阿魏酸(Ⅻ),还分到儿茶酚(X)、大黄素(XⅣ)。结论:除化合物Ⅵ、Ⅶ外,其余均为在该植物中首次分得,其中化合物Ⅱ～Ⅴ、Ⅺ、X、X为该属植物中首次分得。
文摘AIM: To investigate the chemical constituents of Iris tectorum Maxim. METHOD: The chemical constituents were isolated and purified by solvent extraction together with various chromatographic techniques. The structures were elucidated on the basis of chemical evidence and spectral data. RESULTS: Seven compounds were isolated from the EtOAc extracts of the rhizome of Iris tectorum Maxim.,which were apocynin (Ⅰ),rhamnocitrin (Ⅱ),tectorigenin (Ⅲ),iristectorigenin A (Ⅳ),β-sitosterol(Ⅴ),dihydrokaempferide (Ⅵ) ,irigenin(Ⅶ);seven compounds were isolated from the n-BuOH extracts,which were tectoridin (Ⅷ),androsin (Ⅸ),n-Butyl-β-D-fructopyranoside (Ⅹ),iristectorin B (Ⅺ),iridin (Ⅻ),tectorigenin-7-O-β-glucosyl-4′-O-β-glucoside (),daucosterol (■). CONCLUSION: Compound Ⅱ,Ⅵ,Ⅹ were isolated from Iris for the first time.
文摘Derivation conditions of pre-column derivation-HPLC method used for determinating artemisinin content were compared and selected,and artemisinin content in above-ground part of Artemisia annua L.from seventeen locations was compared by optimal pre-column derivation-HPLC method.The optimal derivation condition is selected via comparing of 0.2% NaOH solution addition(3,4,5,6 and 7 mL),derivation temperature(30 ℃,35 ℃,40 ℃,45 ℃ and 50 ℃) and derivation time(0,2,5,10,20,40 and 60 min) during derivation process.The optimal derivation condition is adding 5 mL 0.2% NaOH solution,then insulating in 40 ℃ water bath for 10 min.Differences of artemisinin content in A.annua from seventeen locations are obvious,the general trend is that artemisinin content decreases gradually with location from south to north,in which artemisinin content in A.annua from Youyang of Chongqing is the highest with a value of 7.08 mg·g-1.The method is simple and accurate with good reproducibility,and can be used to determinate artemisinin content in medicinal material of A.annua.
文摘Thirteen compounds were isolated from dry above-ground part of Scutellaria barbata D.Don and their structures were identified.These compounds are p-hydroxybenzaldehyde(Ⅰ),p-coumaric acid(Ⅱ),hydroxyhydroquinone(Ⅲ),hispidulin(IV),5,7,4′-trihydroxy-8-methoxyflavone(Ⅴ),apigenin(Ⅵ),luteolin(Ⅶ),apigenin-5-O-β-D-glucopyranoside(Ⅷ),scutellaric acid(Ⅸ),stigmasta-5,22-dien-3-O-β-D-glucopyranoside(Ⅹ),barbatin C(Ⅺ),β-sito-sterol(Ⅻ) and daucosterol(ⅩⅢ).Compound Ⅷ is isolated from Scutellaria L.for the first time,and compound Ⅲ and compound X are isolated from S.barbata for the first time.
