Preliminary clinical application of total free-breathing cardiac MR examination

Objective To observe the clinical application value of total free-breathing cardiac MR(CMR)examination preliminarily.Methods Two patients who underwent CMR scanning under free-breathing state,including cine,motion correction T1 and T2 mapping,blood flow imaging,and late gadolinium enhancement scanning were retrospectively enrolled,and the qualities of the above images were evaluated and compared with that of conventional CMR images under breath-holding state.Results No significant difference of imaging quality was found between total free-breathing and conventional breath-holding CMR.The differences of left ventricular ejection fraction,cardiac output,left ventricular end-diastolic volume index and left ventricular mass measured based on CMR images under different breath conditions were limited.Conclusion Total free-breathing CMR was feasible in clinical practice,which could provide"one-stop"evaluation of cardiac structure,function and myocardial histological characteristics,hence having promising clinical prospects.

Patient Blood Management:Single Center Evidence and Practice at Fuwai Hospital

Blood loss and blood transfusion requirement are important quality control indicators of cardiovascular surgery and cardiovascular anesthesia.Patient blood management(PBM)is an evidence-based,multidisciplinary approach to optimizing the care of patients who may need transfusion,which encompasses anemia management,hemodilution,cell salvage,hemostatic treatment,and other approaches to reducing bleeding and minimizing blood transfusion.PBM in cardiovascular surgery is a"team sport"that involves cardiac and vascular surgeons,anesthesiologists,perfusionist,intensivists,and other health care providers.The current work provides an overview of evidence and practice of PBM at Fuwai Hospital.Implementation of PBM should also take local resource availability and costeffectiveness of different devices,drugs,technologies,and techniques into consideration.

Aortic Valve Replacement for Patients with Heyde Syndrome:A Literature Review

Objective To explore the characteristics and clinical outcomes of patients with Heyde syndrome(HS)who undergo aortic valve replacement(AVR).Methods Electronic databases including Pub Med,Embase,Ovid,WANFANG,VIP and CNKI were searched to identify all case reports of HS patients undergoing AVR surgery,using different combinations of search terms"Heyde syndrome","gastrointestinal bleeding","aortic stenosis",and"surgery".Three authors independently extracted the clinical data including the patients’characteristics,aortic stenosis severity,gastrointestinal bleeding sites,surgical treatments and prognosis.Results Finally,46 case reports with 55 patients aging from 46 to 87 years,were determined eligible and included.Of them,1 patient had mild aortic stenosis,1 had moderate aortic stenosis,42 had severe aortic stenosis,and 11 were not mentioned.Gastrointestinal bleeding was detected in colon(n=8),jejunum(n=6),ileum(n=4),cecum(n=3),duodenal(n=3)and multiple sites(n=8).No specific bleeding site was identified in 23 patients.Preoperative hemoglobin level ranged from 43 to 117 g/L.All but one of 16 patients showed decreased level of high molecule weight von Willebrand factor.Of the 55 patients,43 underwent AVR,and 12 received transcatheter AVR.Aortic valves of 14 cases were replaced by mechanical valves,and 33 cases by biological valves.All patients recovered well during the follow-up,except 5 patients.One patient who had perivalvular leakage and gastrointestinal bleeding after AVR underwent the second AVR.Two patients had recurrent gastrointestinal bleeding.Two patients died of life-threatening acute subdural hematoma and multiple organ failure,respectively.Conclusions HS is a rare syndrome characterized by aortic stenosis and gastrointestinal bleeding.AVR is an effective treatment for HS.

实时三维超声心动图联合斑点追踪技术评价不同部位起搏对右室功能的影响

目的应用实时三维超声心动图联合斑点追踪技术研究不同部位起搏对右室功能的影响。方法选取2018年12月至2019年6月行双腔起搏器植入术患者90例,并根据起搏部位不同分为右室心尖组(RVAP组)、右室间隔组(RVSP组)、希氏束组(HBP组)。术前及术后6个月分别测量二维超声参数,同时采集实时三维超声心动图像并分析右室舒张末期容积、右室收缩末期容积、右室射血分数,应用斑点追踪技术获得右室间隔纵向应变及右室游离壁纵向应变。比较三组间及组内上述指标术前及术后变化。结果术后6个月组间三尖瓣环e’有统计学差异(P=0.04),RVAP组明显小于其他两组,且RVAP组术后6个月e’及a’均较术前明显减低(P<0.05)。术前及术后三组间右室舒张末期容积、右室收缩末期容积、右室射血分数无明显统计学差异(P>0.05)。术后6个月组间应变指标有明显统计学差异(P=0.01,P=0.02),RVAP组明显低于RVSP组及HBP组。结论实时三维超声心动图联合斑点追踪技术是评估不同部位起搏方式术后早期右室功能的可靠方法。RVSP及HBP术后右室功能优于RVAP,为安全、有效的起搏方式。