原发性干燥综合征(Primary Sjögren’s syndrome, pSS)是一种自身免疫性疾病,疾病的发生及发展状况与血液中自身抗体的形成与沉积相关,长期的疾病状态,患者易产生焦虑、抑郁等不良情绪,但其发病机制均尚不明确。本文从pSS的生物学...原发性干燥综合征(Primary Sjögren’s syndrome, pSS)是一种自身免疫性疾病,疾病的发生及发展状况与血液中自身抗体的形成与沉积相关,长期的疾病状态,患者易产生焦虑、抑郁等不良情绪,但其发病机制均尚不明确。本文从pSS的生物学标志物,疾病受累器官和合并焦虑、抑郁不良情绪3方面进行综述,为临床医生提供更加全面和深入的疾病认识,为患者的诊断和治疗提供更加精准和有效的支持。Primary Sjogren’s syndrome (pSS) is an autoimmune disease;the occurrence and development of the disease is related to the formation and deposition of autoantibodies in the blood;in long-term disease state, patients are prone to anxiety, depression and other adverse emotions, but its pathogenesis is still unclear. In this paper, the biological markers of pSS, the organs involved in the disease, and the associated anxiety and depression were reviewed, so as to provide clinicians with a more comprehensive and in-depth understanding of the disease and provide more accurate and effective support for the diagnosis and treatment of patients.展开更多
文摘原发性干燥综合征(Primary Sjögren’s syndrome, pSS)是一种自身免疫性疾病,疾病的发生及发展状况与血液中自身抗体的形成与沉积相关,长期的疾病状态,患者易产生焦虑、抑郁等不良情绪,但其发病机制均尚不明确。本文从pSS的生物学标志物,疾病受累器官和合并焦虑、抑郁不良情绪3方面进行综述,为临床医生提供更加全面和深入的疾病认识,为患者的诊断和治疗提供更加精准和有效的支持。Primary Sjogren’s syndrome (pSS) is an autoimmune disease;the occurrence and development of the disease is related to the formation and deposition of autoantibodies in the blood;in long-term disease state, patients are prone to anxiety, depression and other adverse emotions, but its pathogenesis is still unclear. In this paper, the biological markers of pSS, the organs involved in the disease, and the associated anxiety and depression were reviewed, so as to provide clinicians with a more comprehensive and in-depth understanding of the disease and provide more accurate and effective support for the diagnosis and treatment of patients.
