基金国家自然科学基金资助项目(81202535)%湖南省科技厅自然科学基金资助项目(2018JJ6097)%湖南省卫生计生委资助课题(B2017183)%郴州市科技局资助项目(jsyf2017025)China National Natural Science Foundation(81202535)%Natural Science Fund Project of Hunan Science and Technology Department(2018JJ6097)%Hunan Provincial Health and Family Planning Commission Fund Project(B2017183)%Chenzhou Science and Technology Bureau Fund Project(jsyf2017025)