Objective To study the surgical outcome of intracerebral lesion with epilepsy. Methods 24 cases were studied. EEG showed that localized epileptiform waves were found in 13 cases, localized slow waves in 5 cases, and n...Objective To study the surgical outcome of intracerebral lesion with epilepsy. Methods 24 cases were studied. EEG showed that localized epileptiform waves were found in 13 cases, localized slow waves in 5 cases, and no epileptiform wave in 6 cases. All cases were performed ECoG monitoring during the operations. 11 patients whose epileptogenic foci were in the surface of lesions or adjacent to the edge of lesions received clearance of focal lesion plus epileptogenic foci resection. Among 8 patients whose epileptogenic foci were more than 10 mm distance from the edge of lesion, 6 received clearance of focal lesion plus cortical excision whose epileptogenic foci were in the area of nonfunctional cortexes, 2 plus partial cortex thermocoagulation whose epileptogenic foci were in the area of functional cortexes. 2 cases whose epileptogenic foci in the depth of anterior temporal lobe received anterior temporal lobotomy plus clearance of focal lesion. 3 patients with no epileptiform wave received clearance of focal lesion simply. Results In 21 cases that performed epileptogenic foci resection, the complete control of seizure has been obtained in 15 cases (71%), the significant reduction in 2 cases (10%), and the reduction in 4 cases (19%). Conclusion The epileptogenic foci can often be precisely located through ECoG monitoring and depth electrode record during the operations for the patients who have intracerebral lesion with epilepsy. The outcome was satisfactory who recieved clearance of focal lesion plus epileptogenic foci surgical treatment.展开更多
文摘Objective To study the surgical outcome of intracerebral lesion with epilepsy. Methods 24 cases were studied. EEG showed that localized epileptiform waves were found in 13 cases, localized slow waves in 5 cases, and no epileptiform wave in 6 cases. All cases were performed ECoG monitoring during the operations. 11 patients whose epileptogenic foci were in the surface of lesions or adjacent to the edge of lesions received clearance of focal lesion plus epileptogenic foci resection. Among 8 patients whose epileptogenic foci were more than 10 mm distance from the edge of lesion, 6 received clearance of focal lesion plus cortical excision whose epileptogenic foci were in the area of nonfunctional cortexes, 2 plus partial cortex thermocoagulation whose epileptogenic foci were in the area of functional cortexes. 2 cases whose epileptogenic foci in the depth of anterior temporal lobe received anterior temporal lobotomy plus clearance of focal lesion. 3 patients with no epileptiform wave received clearance of focal lesion simply. Results In 21 cases that performed epileptogenic foci resection, the complete control of seizure has been obtained in 15 cases (71%), the significant reduction in 2 cases (10%), and the reduction in 4 cases (19%). Conclusion The epileptogenic foci can often be precisely located through ECoG monitoring and depth electrode record during the operations for the patients who have intracerebral lesion with epilepsy. The outcome was satisfactory who recieved clearance of focal lesion plus epileptogenic foci surgical treatment.