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寒露至,如何保护心血管
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作者 万颖颖 徐浩 《保健医苑》 2024年第10期20-21,共2页
度过国庆长假,便迎来了寒露节气。寒露是二十四节气中的第十七个节气,是秋季的第五个节气。《孝经纬》日:“秋分后十五日,斗指辛,为寒露,谓露冷寒而将欲凝结。”古人把“露”作为天气转凉变冷的重要象征。与白露之由热转凉、暑气尚未消... 度过国庆长假,便迎来了寒露节气。寒露是二十四节气中的第十七个节气,是秋季的第五个节气。《孝经纬》日:“秋分后十五日,斗指辛,为寒露,谓露冷寒而将欲凝结。”古人把“露”作为天气转凉变冷的重要象征。与白露之由热转凉、暑气尚未消尽不同,此时已进入深秋,寒露气温比白露时更低,天气由凉转冷,地面的露水更冷,快要凝结成霜了,正所谓“寒露寒露,遍地冷露。” 展开更多
关键词 二十四节气 保护心血管 白露 秋分 凝结
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肺通口服液治疗特发性肺纤维化的临床研究 被引量:6
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作者 樊茂蓉 张燕萍 +7 位作者 苗青 张琼 陶凯 杨艳平 肖伟 魏葆琳 闫锡新 黄继汉 《中药新药与临床药理》 CAS CSCD 北大核心 2013年第3期317-322,共6页
目的评价肺通口服液治疗气阴两虚兼痰瘀交阻型特发性肺纤维化的有效性及安全性。方法试验采用随机、双盲双模拟、阳性药平行对照、多中心、非劣性的临床试验方法,共纳入253例受试者,随机分为肺通大剂量组(84例)、小剂量组(85例)和对照组... 目的评价肺通口服液治疗气阴两虚兼痰瘀交阻型特发性肺纤维化的有效性及安全性。方法试验采用随机、双盲双模拟、阳性药平行对照、多中心、非劣性的临床试验方法,共纳入253例受试者,随机分为肺通大剂量组(84例)、小剂量组(85例)和对照组(84例),疗程12周,观察肺通口服液治疗特发性肺纤维化的疗效及安全性。结果在疾病疗效比较中,肺通大剂量组非劣效于对照组;肺通大剂量组患者生活质量明显优于对照组(P<0.05);6 min步行距离、血气分析(动脉血氧分压、动脉血氧饱和度、肺泡动脉氧分压差)及肺功能(肺总量、一氧化碳弥散能力)等指标比较,肺通大剂量组有优于对照组及肺通小剂量组的趋势,但差异无显著性意义。肺通大、小剂量组不良反应发生率明显低于对照组。结论肺通口服液治疗特发性肺纤维化(气阴两虚兼痰瘀交阻型)安全有效。 展开更多
关键词 肺通口服液 醋酸泼尼松片 随机对照试验 特发性肺纤维化 气阴两虚兼痰瘀交阻型
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从“本虚”论治难治性过敏性紫癜思路浅析 被引量:10
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作者 王文乾 万盈盈 +3 位作者 孙文婷 杨家熙 王皓男 寇秋爱 《环球中医药》 CAS 2022年第8期1427-1430,共4页
中医认为“风、湿、热、毒、瘀、虚”为过敏性紫癜主要病理因素,多从祛邪、清热、利湿、解毒等标实方面论治为主。而对于难治性过敏性紫癜,其反复发作、久病难愈甚则累及肾脏之根本在于本虚。卫气肥腠理、司开合,卫虚则易感风湿外邪,令... 中医认为“风、湿、热、毒、瘀、虚”为过敏性紫癜主要病理因素,多从祛邪、清热、利湿、解毒等标实方面论治为主。而对于难治性过敏性紫癜,其反复发作、久病难愈甚则累及肾脏之根本在于本虚。卫气肥腠理、司开合,卫虚则易感风湿外邪,令气血失和,血不循经;脾为后天之本,脾虚气不足则脉道失于固摄,劳则即发,又能生湿化毒灼伤血络,缠绵不愈;久则及肾,肾虚封藏、固涩失职,尿频、蛋白尿等变证丛生。因此临证时,应将“扶正”思想贯穿疾病治疗的各个阶段。尽管发作期,症见斑色红肿、皮肤发热,以寒凉之药清热解毒治其标为主,但应中病即止,不可过用伤正,此期反复,邪热之毒伤津耗气,故亦应兼以益气养阴,临证时可予疮疡三两三合生脉饮加减,标本兼治;紫癜消退期应恢复脾升清降浊之功用,杜生湿之源、散已生之湿,同时能益气摄血、培土实卫,此期以补中益气汤加减旨在从本控制发作;病及于肾,当阴阳兼顾,以六味地黄丸加减,复肾气化、固涩之功,改善预后。 展开更多
关键词 过敏性紫癜 难治性 血症 成人 本虚 分阶段论治 扶正
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Acupuncture for chronic rhinosinusitis and related postoperative pain:A systematic review and network meta-analysis 被引量:2
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作者 Ling-li QIN Lei JIANG +7 位作者 Xian LI Xue-ying ZHU Li-zhen CAI Guang-di HU Wei-jia SUN Xiao LIANG Yun-ling ZHANG Lu ZHANG 《World Journal of Acupuncture-Moxibustion》 CSCD 2022年第2期89-100,共12页
Background:The network meta-analysis system was used to evaluate the efficacy of various acupuncture and moxibustion techniques for chronic rhinosinusitis(CRS)and related postoperative pain.Methods:An electronic searc... Background:The network meta-analysis system was used to evaluate the efficacy of various acupuncture and moxibustion techniques for chronic rhinosinusitis(CRS)and related postoperative pain.Methods:An electronic search of PubMed,Embase,Web of Science,Cochrane Library,OVID(the Offshore Vessel Inspection Database),CNKI,Wanfang,VIP,and CBM databases was conducted to identify randomised controlled trials on acupuncture and moxibustion for CRS and related postoperative pain from database inception to February 2021.The study included randomised controlled trials(RCTs)published in China and other countries in languages limited to Chinese and English.Primary studies included treated individuals without limitations on age,gender,or nationality and diagnosed as CRS.The total effective rate,visual analogue scale(VAS)score,and symptom and sign score were the primary outcomes.Evidence quality and risk-of-bias were determined.Network meta-analysis was performed.Results:Nineteen articles were included,involving 11 types of intervention measures.The pairwise comparisons showed that both acupuncture therapy combined with drugs(ATD)and sphenopalatine ganglion acupuncture combined with drugs(SGAD)were superior to western medicine(WM)in improving the total effective rate,and ATD was superior to manual acupuncture therapy(MAT),WM,and placebo(PL).In reducing the VAS score,both ATD and SGAD were superior to WM.Point-through-point acupuncture combined with pricking blood therapy(PABT)was superior to MAT.In reducing symptom and sign score,ATD was superior to WM and PL.PABT was superior to MAT.The results of network meta-analysis showed that ATD was superior to MAT,Traditional Chinese medicine(TCM),and WM in improving the total effective rate.In reducing the symptom and sign score,ATD was superior to PL,WM,MAT,and sham acupuncture(SA).PL was superior to MAT,WM,and SA.and PABT was superior to MAT and SA,MAT was superior to WM.There was no significant difference between the intervention measures in reducing the VAS score.The surface under the cumulative ranking curve showed that ATD had the best effect in improving the total effective rate and reducing the VAS and symptom and sign score.Conclusion:ATD was the best method for improving the total effective rate and reducing the VAS and symptom and sign score in the treatment of CRS and related postoperative pain.However,considering the current study quantity and quality,multicentre and high-quality clinical studies with larger sample sizes are needed to verify our findings. 展开更多
关键词 ACUPUNCTURE Chronic rhinosinusitis Postoperative pain NETWORK META-ANALYSIS
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Three previously undescribed steroidal glycoalkaloids from Solanum lyratum and their anti-tumor activities 被引量:1
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作者 Liangyu Liu Yuke Yang +2 位作者 Xiao Du Tong Wu Jiannong Wang 《Journal of Chinese Pharmaceutical Sciences》 CAS CSCD 2022年第3期192-201,共10页
In the present study,three previously undescribed steroidal glycoalkaloids(compounds 1–3)were isolated from Solanum lyratum.Their structures were elucidated based on comprehensive spectroscopic data.Their anti-angiog... In the present study,three previously undescribed steroidal glycoalkaloids(compounds 1–3)were isolated from Solanum lyratum.Their structures were elucidated based on comprehensive spectroscopic data.Their anti-angiogenesis and anti-metastatic activities were evaluated by MTT and wound-healing assays,respectively.Tumor-derived vascular endothelial cells(TdECs),obtained by co-culture of A549 and human umbilical vein endothelial cells(HUVECs),were treated with compounds 1–3.Results showed that compounds 1–3 significantly inhibited the migration of TdECs at 25μM despite the weak cytotoxic activities,which indicated that the compounds exerted anti-tumor activities by inhibiting metastasis,rather than directly inhibiting the proliferation of TdECs. 展开更多
关键词 Solanum lyratum Steroidal glycoalkaloids ANTI-TUMOR METASTASIS ANGIOGENESIS
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Two new glycoalkaloids from Solanum lyratum Thunb.
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作者 Tong Wu Xiao Du +2 位作者 Jiannong Wang Liangyu Liu Yuke Yang 《Journal of Chinese Pharmaceutical Sciences》 CAS CSCD 2021年第6期518-523,共6页
To study the alkaloids of Solanum lyratum Thunb.ODS and silica gel column chromatography combined with HPLC were used to separate and purify the alkaloids.Seven alkaloids were identified via UHPLC-ESI-Q-TOF-MS,1 D and... To study the alkaloids of Solanum lyratum Thunb.ODS and silica gel column chromatography combined with HPLC were used to separate and purify the alkaloids.Seven alkaloids were identified via UHPLC-ESI-Q-TOF-MS,1 D and 2 D NMR,respectively 15β-ethoxy-(3β,5α,25 R)-16,23-epoxy-23,24-imino-cholestan-16,20,23(N)-triene-3β-ol-3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl-(1→4)-β-D-galactopyran-oside(1),15β-hydroxyl-(3β,25 R)-16,23-epoxy-23,24-imino-cholestan-5,16,20,23(N)-tetraene-3β-ol-3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl-(1→4)-β-D-galactop-yranoside(2),Solalyraine A(3),Solalyraine B(4),16,23-epoxy-22,26-imino-cholest-22(N),23,25(26)-trien-3β-ol-3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside(5),N-(4-amino-butyl)-3-(3-hydroxy-4-methoxy-phenyl)-E-acrylamide(6)and magnoflorine(7).Among them,compounds 1 and 2 were two new steroidal glycoalkaloids that has not been reported in the literature,and compound 7 was isolated from S.lyratum for the first time. 展开更多
关键词 Solanum lyratum Thunb. Steroidal glycoalkaloids Chemical constituents Structure identification
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