Traditional Chinese medicine(TCM)has played an important role in the prevention and control of coronavirus disease 2019(COvID-19)and has received considerable attention from all sectors of society.In the current situa...Traditional Chinese medicine(TCM)has played an important role in the prevention and control of coronavirus disease 2019(COvID-19)and has received considerable attention from all sectors of society.In the current situation of the global outbreak,it is crucial to promote the global application of TCM.However,the pandemic has also exposed various problems affecting the widespread acceptance of TCM.In this review,we summarize efforts to prevent and control cOoVID-19 by TCM and provide strategic guidance on how to promote its practice in the context of public health emergencies by(1)completing the system for evaluating the clinical efficacy of TCM;(2)transforming decoctions into Chinese patent medicines;(3)encouraging low-threshold traditional rehabilitation therapy;(4)strengthening communication and cooperation with the media.The aim of these approaches is to improve the rigor of TCM research and its dissemination,sharing the antiepidemic experience of TCM to the world,as well as increase the engagement of and acceptance by the masses.In this manner,TCM will not only aid in preventing and controlling CoVID-19 but can also provide tools for coping withfuture public health emergencies.展开更多
Acute fatty liver of pregnancy(AFLP)is an idiopathic disease with acute and critical onset.Although the incidence of AFLP is relatively low,its mortality remains high.When AFLP is complicated with multi-organ dysfunct...Acute fatty liver of pregnancy(AFLP)is an idiopathic disease with acute and critical onset.Although the incidence of AFLP is relatively low,its mortality remains high.When AFLP is complicated with multi-organ dysfunction syndrome(MODS)and severe infection,especially hematogenous infection caused by multidrug-resistant pathogens,treatment becomes extremely difficult with an even lower survival rate.In the present work,we reported a 31-year-old primipara woman who developed AFLP complicated with MODS and severe infection at 37+5 weeks of gestation and received treatment in our hospital.The result of fast blood culture was positive for carbapenem-resistant Klebsiella pneumonia(CRKP).Based on this finding in combination with the results of drug sensitivity test,the quadruple regime using scheme imipenem cilastatin sodium,tigecycline,polymyxin and fosfomycin was implemented,and the patient was successfully cured.Successful treatment of pregnant women with AFLP complicated with MODS and/or hematogenous infection of CRKP can be achieved by using individualized combined antibiotic therapies on the basis of fast blood culture and combined drug sensitivity test.In this case,the patient was in a critical situation.In the treatment process,clinicians,clinical pharmacists and microbiologists should cooperate with each other and discuss the treatment plan together according to the pathophysiological characteristics of the patient,which was one of the key factors for successful treatment of the patient.展开更多
文摘Traditional Chinese medicine(TCM)has played an important role in the prevention and control of coronavirus disease 2019(COvID-19)and has received considerable attention from all sectors of society.In the current situation of the global outbreak,it is crucial to promote the global application of TCM.However,the pandemic has also exposed various problems affecting the widespread acceptance of TCM.In this review,we summarize efforts to prevent and control cOoVID-19 by TCM and provide strategic guidance on how to promote its practice in the context of public health emergencies by(1)completing the system for evaluating the clinical efficacy of TCM;(2)transforming decoctions into Chinese patent medicines;(3)encouraging low-threshold traditional rehabilitation therapy;(4)strengthening communication and cooperation with the media.The aim of these approaches is to improve the rigor of TCM research and its dissemination,sharing the antiepidemic experience of TCM to the world,as well as increase the engagement of and acceptance by the masses.In this manner,TCM will not only aid in preventing and controlling CoVID-19 but can also provide tools for coping withfuture public health emergencies.
基金National Natural Science Foundation of China(Grant No.81470390)Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support(Grant No.20152218)+1 种基金Shanghai Sailing Program(Grant No.19YF1431700)Clinical Trial of Xinhua Hospital(Grant No.15LC11)。
文摘Acute fatty liver of pregnancy(AFLP)is an idiopathic disease with acute and critical onset.Although the incidence of AFLP is relatively low,its mortality remains high.When AFLP is complicated with multi-organ dysfunction syndrome(MODS)and severe infection,especially hematogenous infection caused by multidrug-resistant pathogens,treatment becomes extremely difficult with an even lower survival rate.In the present work,we reported a 31-year-old primipara woman who developed AFLP complicated with MODS and severe infection at 37+5 weeks of gestation and received treatment in our hospital.The result of fast blood culture was positive for carbapenem-resistant Klebsiella pneumonia(CRKP).Based on this finding in combination with the results of drug sensitivity test,the quadruple regime using scheme imipenem cilastatin sodium,tigecycline,polymyxin and fosfomycin was implemented,and the patient was successfully cured.Successful treatment of pregnant women with AFLP complicated with MODS and/or hematogenous infection of CRKP can be achieved by using individualized combined antibiotic therapies on the basis of fast blood culture and combined drug sensitivity test.In this case,the patient was in a critical situation.In the treatment process,clinicians,clinical pharmacists and microbiologists should cooperate with each other and discuss the treatment plan together according to the pathophysiological characteristics of the patient,which was one of the key factors for successful treatment of the patient.
