目的:探究蒙古扁桃油对实验高脂血症大鼠血脂水平及肝脏功能的影响。方法:80只雄性Wistar大鼠按体重均衡随机分成8组:空白对照组、蒙古扁桃油对照组、高脂模型组、蒙古扁桃油组(A、B、C、D)、橄榄油对照组,除空白对照组和蒙古扁桃油对...目的:探究蒙古扁桃油对实验高脂血症大鼠血脂水平及肝脏功能的影响。方法:80只雄性Wistar大鼠按体重均衡随机分成8组:空白对照组、蒙古扁桃油对照组、高脂模型组、蒙古扁桃油组(A、B、C、D)、橄榄油对照组,除空白对照组和蒙古扁桃油对照组给予基础饲料,其余组均供给高脂饲料。5周建立高脂血症模型,蒙古扁桃油对照组(按每公斤体重给予10 m L/kg蒙古扁桃油灌胃)、蒙古扁桃油组(A:10、B:7.5、C:5、D:2.5 m L/kg)、橄榄油对照组(10 m L/kg橄榄油),空白组与模型组灌胃给予生理盐水。5周后,采样计算肝脏指数,测定血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)和肝组织丙二醛(MDA)、超氧化物歧化酶(SOD)、还原型谷胱甘肽(GSH),拟合量效关系曲线,观察肝脏组织学病理变化。结果:10 m L/kg和7.5 m L/kg的蒙古扁桃油显著降低高脂血症大鼠血清总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)浓度(p <0.05),不同剂量蒙古扁桃油均显著降低肝脏丙二醇(MDA)的含量(p <0.05),10 m L/kg和2.5 m L/kg蒙古扁桃油显著提高肝脏超氧化物歧化酶(SOD)活性和谷胱甘肽(GSH)的含量(p <0.05)。结论:蒙古扁桃油具有调血脂、提高肝脏抗氧化和保护肝脏组织的作用,且最佳剂量在2.5 m L/kg≤Y≤10 m L/kg范围内。展开更多
Objective: To study anxiety, depression, life events and coping style of the middle school students. Methods: SAS, SDS, Adolescent Self-rating Life Events Checklist, and Coping Style Questionnaire were administered to...Objective: To study anxiety, depression, life events and coping style of the middle school students. Methods: SAS, SDS, Adolescent Self-rating Life Events Checklist, and Coping Style Questionnaire were administered to 331 junior middle school students. Results: Prevalence rates for anxiety and depression were 26.59% and 31.42% respectively. Significant correlations were found between life events and SAS scores. Negative coping style was positively correlated with scores on SAS and SDS. Conclusion: Reducing school work load, reduced use of criticism and punishment, reduced dependant and negative coping style, and increased harmonious relationship are important strategies for reducing anxiety and depression among middle school students.展开更多
文摘目的:探究蒙古扁桃油对实验高脂血症大鼠血脂水平及肝脏功能的影响。方法:80只雄性Wistar大鼠按体重均衡随机分成8组:空白对照组、蒙古扁桃油对照组、高脂模型组、蒙古扁桃油组(A、B、C、D)、橄榄油对照组,除空白对照组和蒙古扁桃油对照组给予基础饲料,其余组均供给高脂饲料。5周建立高脂血症模型,蒙古扁桃油对照组(按每公斤体重给予10 m L/kg蒙古扁桃油灌胃)、蒙古扁桃油组(A:10、B:7.5、C:5、D:2.5 m L/kg)、橄榄油对照组(10 m L/kg橄榄油),空白组与模型组灌胃给予生理盐水。5周后,采样计算肝脏指数,测定血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)和肝组织丙二醛(MDA)、超氧化物歧化酶(SOD)、还原型谷胱甘肽(GSH),拟合量效关系曲线,观察肝脏组织学病理变化。结果:10 m L/kg和7.5 m L/kg的蒙古扁桃油显著降低高脂血症大鼠血清总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)浓度(p <0.05),不同剂量蒙古扁桃油均显著降低肝脏丙二醇(MDA)的含量(p <0.05),10 m L/kg和2.5 m L/kg蒙古扁桃油显著提高肝脏超氧化物歧化酶(SOD)活性和谷胱甘肽(GSH)的含量(p <0.05)。结论:蒙古扁桃油具有调血脂、提高肝脏抗氧化和保护肝脏组织的作用,且最佳剂量在2.5 m L/kg≤Y≤10 m L/kg范围内。
文摘Objective: To study anxiety, depression, life events and coping style of the middle school students. Methods: SAS, SDS, Adolescent Self-rating Life Events Checklist, and Coping Style Questionnaire were administered to 331 junior middle school students. Results: Prevalence rates for anxiety and depression were 26.59% and 31.42% respectively. Significant correlations were found between life events and SAS scores. Negative coping style was positively correlated with scores on SAS and SDS. Conclusion: Reducing school work load, reduced use of criticism and punishment, reduced dependant and negative coping style, and increased harmonious relationship are important strategies for reducing anxiety and depression among middle school students.