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中医药为主治疗视网膜中央动脉阻塞1例
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作者 李志英 张淳 +3 位作者 余杨桂 邓燕敏 刘文英 詹敏 《中国中医急症》 2005年第4期381-382,共2页
关键词 视网膜中央静脉阻塞 中医药
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论中医美容学研究思路与方法 被引量:1
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作者 吴慧金 何智健 《中国民族民间医药》 2009年第13期51-52,共2页
中医美容研究的思路和方法是:以中医美容学的基本理论为基础,系统整理古代文献;进行专题深化研究;借助现代科学技术研制新产品;实行学科分化等。加速人才培养以提高整体素质。
关键词 中医美容 学术发展
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面孔识别中梭状回视觉加工的脑功能成像研究 被引量:3
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作者 李健萍 黄勇 《中国医学计算机成像杂志》 CSCD 2008年第4期293-298,共6页
目的:探讨面孔识别中,梭状回视觉加工的基本功能。材料和方法:12位大学生对图片进行名人-非名人和男-女性别判断,以功能磁共振采集数据,AFNI软件处理数据。统计方法,首先画感兴趣区,计算个体感兴趣区的脑激活,用ANOVA和t-test进行组分... 目的:探讨面孔识别中,梭状回视觉加工的基本功能。材料和方法:12位大学生对图片进行名人-非名人和男-女性别判断,以功能磁共振采集数据,AFNI软件处理数据。统计方法,首先画感兴趣区,计算个体感兴趣区的脑激活,用ANOVA和t-test进行组分析。结果:名人判断或性别判断都明显激活了梭状回,对左右侧分刖进行名人与性别的差异性检验,差异性均未达到显著性水平。结论:梭状回不区分名人与非名人,不区分男女性别,激活取决于刺激的物理属性,如新颖程度、鲜明性等客观因素,其功能可能是非特异性的。 展开更多
关键词 梭状回 面孔识别 功能磁共振成像 名人 性别
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慢病毒载体转染内皮祖细胞移植治疗肺动脉高压并黄芪总苷干预
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作者 周小雄 魏伟超 +5 位作者 孙策 叶桃春 王嵩 卿立金 吴辉 冼绍祥 《中国组织工程研究》 CAS 北大核心 2018年第9期1425-1431,共7页
背景:CD40通路的激活对内皮祖细胞的疗效起负向调节作用,而抑制该通路能增强内皮祖细胞的生物学功能。目的:比较CD40基因沉默的内皮祖细胞(shRNA-CD40转染内皮祖细胞)与常规内皮祖细胞移植治疗肺动脉高压模型的疗效,并探讨黄芪总苷在内... 背景:CD40通路的激活对内皮祖细胞的疗效起负向调节作用,而抑制该通路能增强内皮祖细胞的生物学功能。目的:比较CD40基因沉默的内皮祖细胞(shRNA-CD40转染内皮祖细胞)与常规内皮祖细胞移植治疗肺动脉高压模型的疗效,并探讨黄芪总苷在内皮祖细胞移植治疗肺动脉高压中的干预作用。方法:将90只SD大鼠以随机数字表法分为5组,分别为正常对照组(n=24)、模型组(n=24)、慢病毒转染组(n=18)、常规移植组(n=18)及黄芪总苷组(n=6)。除正常对照组外,其余4组均以野百合碱诱发肺动脉高压模型,慢病毒转染组大鼠分别于野百合碱注射后第7,14,21天尾静脉注射Lv-shRNA-CD40转染的内皮祖细胞,每个时间点6只;常规移植组大鼠分别于野百合碱注射后第7,14,21天尾静脉注射内皮祖细胞,每个时间点6只;黄芪总苷组在野百合碱注射后第21天时间点注射Lv-shRNA-CD40转染的内皮祖细胞,同时在第1-21天每日一次给予80 mg/(kg·d)黄芪总苷腹腔注射。野百合碱注射后第28天,进行血流动力学、血浆内皮素1水平与右心室肥大指数检测。结果与结论:(1)与正常对照组比较,模型组右心室压力、平均肺动脉压、右心室肥大指数均升高(P<0.05)。与模型组比较,慢病毒转染组、常规移植组右心室压力、平均肺动脉压、右心室肥大指数均明显下降(P<0.05)。随着移植内皮祖细胞时间的延长,2个细胞移植组右心室压力、平均肺动脉压、右心室肥大指数均有逐渐升高趋势,但慢病毒转染组变化差异不明显;(2)与正常对照组比较,模型组大鼠血浆内皮素1水平升高(P<0.05);与模型组比较,慢病毒转染组、常规移植组血浆内皮素1水平降低(P<0.05);慢病毒转染组相同移植时间点的血浆内皮素1水平低于常规移植组(P<0.05);(3)黄芪总苷组的血流动力学、血浆内皮素1水平及右心室肥大指数均优于慢病毒转染组(P<0.05);(4)结果表明,CD40基因沉默的内皮祖细胞治疗肺动脉高压的效果更明显且更持久,黄芪总苷可增强其治疗效果。 展开更多
关键词 高血压 肺性 内皮细胞 慢病毒感染 CD40配体 黄芪 组织工程
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Network Pharmacology-based Analysis of the Mechanism of Action of the Herb Pair Chai Hu-Bai Shao 被引量:2
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作者 ZHANG Chi GUO Wei +2 位作者 SUN Ling-Ling Chen Han-Rui LIN Li-Zhu 《Digital Chinese Medicine》 2019年第4期227-236,共10页
Objective To analyze the mechanism of action and compatibility of the active compounds of the traditional herb pair Bupleuri Radix(Chai Hu,CH,柴胡)-Paeoniae Radix Alba(Bai Shao,BS,白芍).Methods All chemical compounds ... Objective To analyze the mechanism of action and compatibility of the active compounds of the traditional herb pair Bupleuri Radix(Chai Hu,CH,柴胡)-Paeoniae Radix Alba(Bai Shao,BS,白芍).Methods All chemical compounds related to CH and BS were retrieved from the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform(TCMSP),Traditional Chinese Medicine Integrated Database(TCMID),Bioinformatics Analysis Tool for Molecular mechANism of Traditional Chinese Medicine(Batman-TCM),Traditional Chinese Medicine Database@Taiwan(TCM Database@Taiwan),and the literature.Relevant compounds were screened for oral bioavailability(OB),drug-likeness(DL),and the Caco-2 cell model.The Uniprot,Genecard,and CTD databases were used to obtain information on potential targets and diseases of associated compounds.Based on this,Cytoscape 3.2.1 software,GO enrichment analysis,and KEGG pathway enrichment were used to analyze the potential mechanism of action and pathways of the CH-BS drug combination.Results A total of 23 active compounds of CH and BS were indentified after meeting specific criteria by network pharmacology,showing 79 predicted targets of active compounds.Among them,all targets were associated with 344 diseases,and the compounds in CH and BS were connected to 94 pathways and biological,such as calcium signaling pathway,neuroactive ligand-receptor interaction and TNF signaling pathway.Conclusions Our results preliminarily validated the main compounds in CH-BS herb pair interacted with multiple targets in different diseases,and the molecular mechanism of these compounds involves multiple pathways,thereby establishing a good foundation for further studies. 展开更多
关键词 Bupleuri Radix(Chai Hu 柴胡) Paeoniae Radix Alba(Bai Shao 白芍) Herb pair Network pharmacology Mechanism of action
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5个锻炼动作缓解肩周炎
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作者 袁丽 雷小明 +2 位作者 向孝兵(指导) 邓宝贵(指导) 陈吉珊(指导) 《保健与生活》 2024年第15期24-25,共2页
肩周炎是指肩关节内滑膜及关节囊的慢性炎症反应。因患病后,肩关节活动会慢慢变得越来越受限,仿佛逐渐被冻结或凝固,又称为“冻结肩”“肩凝症”,是50岁左右人群的常见疾病,因此也常被称为“五十肩”。肩周炎的主要表现:疼痛和活动受限。
关键词 冻结肩 关节囊 肩凝症 慢性炎症反应 肩周炎 肩关节 活动受限 五十肩
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PICC导管相关性感染的相关因素分析与护理措施 被引量:1
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作者 肖平 《按摩与康复医学》 2012年第20期113-114,共2页
目的:探讨PICC导管相关性感染的相关因素分析与护理措施。方法:我院收治的患者中共有150例患者进行PICC,对PICC患者发生CPI的相关因素进行分析。结果:CPI发生率为IO.66%;CPI的相关因素有年龄、PICC相关知识的了解情况、操作人员... 目的:探讨PICC导管相关性感染的相关因素分析与护理措施。方法:我院收治的患者中共有150例患者进行PICC,对PICC患者发生CPI的相关因素进行分析。结果:CPI发生率为IO.66%;CPI的相关因素有年龄、PICC相关知识的了解情况、操作人员的经验、导管留置时间以及高渗透压药物的使用。结论:PICC患者发生CPI的相关因素有很多,需要根据相关因素制定有针对性的护理措施,以防止CPI的发生。 展开更多
关键词 PICC导管 感染 相关因素 护理
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Comparative research between acupuncture and Climen in treatment of menopausal hot flashes:A randomized controlled trial
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作者 Hai-tao TU Xin ZHOU +2 位作者 Xun ZHUANG Jun HE Zhong-hao XIONG 《World Journal of Acupuncture-Moxibustion》 CSCD 2021年第4期285-290,共6页
Objective:To compare the therapeutic effect on menopausal hot flashes between acupuncture and Climen so as to provide a new approach to the treatment of this disease.Methods:A total of 80 cases in line with inclusion ... Objective:To compare the therapeutic effect on menopausal hot flashes between acupuncture and Climen so as to provide a new approach to the treatment of this disease.Methods:A total of 80 cases in line with inclusion criteria were randomized into a treatment group(treated with acupuncture) and a control group(oral administration with climen),40 cases in each one.The treatment for 1 month was as 1 course and lasted consecutively for 2 courses.Before and after treatment,the contents of serum estrogen(estradiol,E_(2)) and 5-hydroxytryptamine(HT) and the scores of the attack frequency and severity scale of hot flashes and sweating,domestic modified Kupperman scale and traditional Chinese medicine(TCM) symptom scale were observed,and the clinical therapeutic effect was evaluated in the two groups separately.Results:Before treatment,there was no difference in the content of E_(2) and 5-HT,the score of hot flashes and sweating,Kupperman score and TCM symptom score in the patients between two groups,indicating the comparability(all P>0.05).Compared with the data before treatment,the contents of serum E_(2)(treatment group vs control group:22.24±11.02 vs 33.12±1.01;22.11±10.19 vs 25.29±2.23) and5-HT(treatment group vs control group:96.12±8.21 vs 131.21±30.21;96.98±7.99 vs 108.29±22.08),the score of hot flashes and sweating(treatment group vs control group:8.24±1.02 vs 3.12±1.01;8.11±1.19 vs 5.29±2.23),Kupperman score(treatment group vs control group:26.12±2.21 vs11.21±0.21;26.98±1.99 vs 18.29±2.08) and TCM symptom score(treatment group vs control group:18.97±3.87 vs 10.12±0.16;19.01±2.29 vs 15.61±2.89) were statistically different after treatment in the two groups(all P<0.05).After treatment,the contents of serum E_(2) and 5-HT,the score of hot flashes and sweating,Kupperman score and TCM symptom score in the treatment group were all different statistically compared with the control group(all P<0.05).There was statistical difference in clinical therapeutic effect in the patients between two group,in which,the therapeutic effect in the treatment group was better than that in the control group(90% vs 77.5%,P<0.05).Conclusion:Acupuncture effectively reduces Kupperman score and TCM symptom score in the patients and its therapeutic effect is better than climen.Regarding relieving hot flashes symptoms in menopausal patients of kidney yin deficiency and improving in attack frequency and severity of hot flashes and sweating,the effects of acupuncture are superior to Climen.Acupuncture obviously increases the contents of serum E_(2) and 5-HT. 展开更多
关键词 Menopausal hot flashes Kidney yin deficiency ACUPUNCTURE CLIMEN Randomized controlled trial(RCT)
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Evidence-based assessment of acupuncture skills using a newly developed simulation-based test:A validation study
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作者 Su-jun XIE Zheng WANG +9 位作者 Ying-fang ZHOU Lars KONGE Lai-siqi WAN Xi-jun CAO Xing WAN Yun HU Fang FANG Kang-bai HUANG Liang ZHANG Xun ZHUANG 《World Journal of Acupuncture-Moxibustion》 CSCD 2022年第4期298-304,共7页
Objective:Acupuncture is an efficient treatment modality for many different training,but the technique can be challenging to master.Identification of the different acupuncture points can now be practiced in a standard... Objective:Acupuncture is an efficient treatment modality for many different training,but the technique can be challenging to master.Identification of the different acupuncture points can now be practiced in a standardized and patient-safe simulation-based environment.We aim to gather additional evidence regarding simulation-based training of acupuncture skills and hope that the simulation-based test developed and will be used for simulation-based mastery learning in future develop.Methods:The aim of this study was to develop a test of acupuncture skills using the TCM(Traditional Chinese Medicine) Meridians & Acupoints Anatomy Teaching Platform and gather validity evidence using Messick’s framework.Novice medical students without prior experience in acupuncture(n=43),intermediate medical students who had finished the mandatory acupuncture course(n=24),and skilled acupuncture doctors(n=17) were included in the study.One-hundred and seven acupuncture points were presented to the participants in identical randomized order and they were asked to identify each point by touching the correct anatomical location on the simulator.The simulator automatically registered the accuracy of participants’ answers.Results:The reliability of the final test(66 acupuncture points) was at a high level with a Cronbach’s alpha of 0.98 and only 16 acupuncture points were needed to ensure a reliability of 0.90.The test could discriminate significantly between all three groups and a credible pass/fail-score of 34 points was determined which resulted in eight out of 43(19%) novices passing the test and only two out of 17(12%)experienced failing the test.These consequences were statistically significant(P <0.001).Conclusion:Based on Messick’s framework we demonstrated strong validity evidence for a newly developed simulation-based test of acupuncture points localization skills.The test can be used as an aid to decide when trainees are ready to progress to more advanced training and clinical practice.Compared with the traditional point-point test,the point-point evaluation of the simulator can be more objective and reduce the effort of teachers. 展开更多
关键词 Acupuncture SIMULATION ASSESSMENT Validity Mastery learning
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清明时节喝啥养生佳汤
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作者 蓝森麟 《保健与生活》 2020年第7期40-40,共1页
葛根赤白鲫鱼汤食材:鲜葛根1000克,赤小豆100克,白茯苓30克,白鲫鱼2条(约750克),白酒、盐适量。做法:鲫鱼去鳞、鲍及内脏,洗净,放进油锅内煎至两面金黄色(煎时洒少许白酒);葛根洗干净(别扒皮),切厚块。二者连同洗净的赤小豆、茯苓一齐... 葛根赤白鲫鱼汤食材:鲜葛根1000克,赤小豆100克,白茯苓30克,白鲫鱼2条(约750克),白酒、盐适量。做法:鲫鱼去鳞、鲍及内脏,洗净,放进油锅内煎至两面金黄色(煎时洒少许白酒);葛根洗干净(别扒皮),切厚块。二者连同洗净的赤小豆、茯苓一齐置于砂锅内,加入清水2500毫升、白酒少许,用武火煮沸后改用文火熬1.5小时,精盐调味,即可。 展开更多
关键词 清明时节 白酒 食材 养生 赤小豆 白茯苓 鲫鱼汤 葛根
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