利用核磁共振氢谱(1 H NMR)、氢-氢相关谱(1 H-1 H COSY)、核磁共振碳谱(13 C NMR)、氟谱(19 F NMR)、DEPT谱、异核单量子相关谱(HSQC)、异核多键相关谱(HMBC)对阿伐他汀钙进行了解析,对其所有的NMR谱信号进行了归属。通过氢谱、碳谱、...利用核磁共振氢谱(1 H NMR)、氢-氢相关谱(1 H-1 H COSY)、核磁共振碳谱(13 C NMR)、氟谱(19 F NMR)、DEPT谱、异核单量子相关谱(HSQC)、异核多键相关谱(HMBC)对阿伐他汀钙进行了解析,对其所有的NMR谱信号进行了归属。通过氢谱、碳谱、氟谱以及二维谱技术对该化合物进行了完整的结构分析,使学生对于二维核磁共振技术有了更深的了解,有利于学生正确解析有机化合物结构。展开更多
Carbon dioxide(CO_(2)) is the main greenhouse gas and also an ideal C1 feedstock in organic synthesis because it is abundant,nontoxic,nonflammable,and renewable.The synthesis of organic carbamates using CO_(2) as a ph...Carbon dioxide(CO_(2)) is the main greenhouse gas and also an ideal C1 feedstock in organic synthesis because it is abundant,nontoxic,nonflammable,and renewable.The synthesis of organic carbamates using CO_(2) as a phosgene alternative has attracted extensive attention because of the importance of carbamates in organic synthesis and in the pharmaceutical and agrochemical industries.In recent decades,many multicomponent reaction strategies have been designed for constructing different types of organic carbamate molecules.Most of these methods rely on the in situ generation of carbamate anions from CO_(2) and amines,followed by reactions with other coupling partners.Synthetic strategies for acyclic carbamates include nucleophile‐electrophile coupling,nucleo‐phile‐nucleophile oxidative coupling,difunctionalization of unsaturated hydrocarbons,and C–H bond functionalization.Strategies for the synthesizing cyclic carbamates include carboxylative cyclization of in situ‐generated unsaturated amines and difunctionalization of unsaturated amines with CO_(2) and other electrophilic reagents.This review summarizes the recent advances in the synthesis of organic carbamates from CO_(2) using different multicomponent reaction strategies.Future perspectives and challenges in the incorporation of CO_(2) into carbamates are also presented.展开更多
氰氟虫腙是一种新型的缩氨基脲类杀虫剂。利用核磁共振氢谱(1 H NMR)、氢-氢相关谱(1 H-1 H COSY)、核磁共振碳谱(13 C NMR)、氟谱(19F NMR)、DEPT谱、异核单量子相关谱(HSQC)、异核多键相关谱(HMBC)对氰氟虫腙进行了解析,对其所有的NM...氰氟虫腙是一种新型的缩氨基脲类杀虫剂。利用核磁共振氢谱(1 H NMR)、氢-氢相关谱(1 H-1 H COSY)、核磁共振碳谱(13 C NMR)、氟谱(19F NMR)、DEPT谱、异核单量子相关谱(HSQC)、异核多键相关谱(HMBC)对氰氟虫腙进行了解析,对其所有的NMR谱信号进行了归属。通过氢谱、碳谱、氟谱以及二维谱技术对该化合物进行了完整的结构分析,为氰氟虫腙的质量研究提供较为全面的参考依据。展开更多
文摘利用核磁共振氢谱(1 H NMR)、氢-氢相关谱(1 H-1 H COSY)、核磁共振碳谱(13 C NMR)、氟谱(19 F NMR)、DEPT谱、异核单量子相关谱(HSQC)、异核多键相关谱(HMBC)对阿伐他汀钙进行了解析,对其所有的NMR谱信号进行了归属。通过氢谱、碳谱、氟谱以及二维谱技术对该化合物进行了完整的结构分析,使学生对于二维核磁共振技术有了更深的了解,有利于学生正确解析有机化合物结构。
基金广东省功能分子工程重点实验室资助课题,Supported by the Open Fund of the Key Laboratory of Functional Molecular Engineering of Guangdong Province(2017kf02),(South China University of Technology)。
文摘Carbon dioxide(CO_(2)) is the main greenhouse gas and also an ideal C1 feedstock in organic synthesis because it is abundant,nontoxic,nonflammable,and renewable.The synthesis of organic carbamates using CO_(2) as a phosgene alternative has attracted extensive attention because of the importance of carbamates in organic synthesis and in the pharmaceutical and agrochemical industries.In recent decades,many multicomponent reaction strategies have been designed for constructing different types of organic carbamate molecules.Most of these methods rely on the in situ generation of carbamate anions from CO_(2) and amines,followed by reactions with other coupling partners.Synthetic strategies for acyclic carbamates include nucleophile‐electrophile coupling,nucleo‐phile‐nucleophile oxidative coupling,difunctionalization of unsaturated hydrocarbons,and C–H bond functionalization.Strategies for the synthesizing cyclic carbamates include carboxylative cyclization of in situ‐generated unsaturated amines and difunctionalization of unsaturated amines with CO_(2) and other electrophilic reagents.This review summarizes the recent advances in the synthesis of organic carbamates from CO_(2) using different multicomponent reaction strategies.Future perspectives and challenges in the incorporation of CO_(2) into carbamates are also presented.
文摘氰氟虫腙是一种新型的缩氨基脲类杀虫剂。利用核磁共振氢谱(1 H NMR)、氢-氢相关谱(1 H-1 H COSY)、核磁共振碳谱(13 C NMR)、氟谱(19F NMR)、DEPT谱、异核单量子相关谱(HSQC)、异核多键相关谱(HMBC)对氰氟虫腙进行了解析,对其所有的NMR谱信号进行了归属。通过氢谱、碳谱、氟谱以及二维谱技术对该化合物进行了完整的结构分析,为氰氟虫腙的质量研究提供较为全面的参考依据。
