Medication is still the main means for treating liver cirrhosis. However, micro-circulation obstacle in the liver and dynamic abnormality of portal vein flow suggest that liver protecting drugs via peripheral veins ca...Medication is still the main means for treating liver cirrhosis. However, micro-circulation obstacle in the liver and dynamic abnormality of portal vein flow suggest that liver protecting drugs via peripheral veins can hardly give full requirement for their effect. The authors reviewed a new method of percutaneous transhepatic portal vein implantation of port-catheter system for infusion of drugs in the treatment of liver cirrhosis, with theoretical basis and the outlook of application.展开更多
目的评价经皮经肝食管胃底静脉曲张栓塞术的临床应用价值. 方法肝硬化门静脉高压合并食管胃底静脉曲张破裂出血患者30例(24例为食管静脉套扎及硬化治疗术后再次出血;6例为消化道出血未行内镜治疗者).电视透视下取右腋中线或剑突下方穿...目的评价经皮经肝食管胃底静脉曲张栓塞术的临床应用价值. 方法肝硬化门静脉高压合并食管胃底静脉曲张破裂出血患者30例(24例为食管静脉套扎及硬化治疗术后再次出血;6例为消化道出血未行内镜治疗者).电视透视下取右腋中线或剑突下方穿刺进入门静脉分支.用弹簧钢圈、无水乙醇和明胶海绵栓塞食管胃底静脉.2例栓塞后门静脉内留置导管-药盒系统行区域性药物灌注治疗.结果 30例患者胃冠状静脉超选择插管、栓塞全部成功.胃短静脉超选择插管栓塞成功率90%.27例患者术后得到随访,随访2~18个月.17例患者术后胃镜复查显示胃底曲张静脉完全消失者13例,明显改善者4例.2例于栓塞术后1周、2个月再出血,再次栓塞后无再出血.2例门静脉留置药盒行区域性中西药物灌注者治疗后门静脉压力分别下降10 cm H2O(1 cm H2O = 0.098 kPa) 和8 cm H2O.结论经皮经肝食管胃底静脉曲张栓塞术创伤小、止血效果肯定,在急诊止血方面更具优势,应该成为门静脉高压食管胃底静脉曲张破裂出血的常规治疗方法之一.经留置药盒行门静脉区域性中西药物灌注治疗肝硬化值得进一步探讨.展开更多
文摘Medication is still the main means for treating liver cirrhosis. However, micro-circulation obstacle in the liver and dynamic abnormality of portal vein flow suggest that liver protecting drugs via peripheral veins can hardly give full requirement for their effect. The authors reviewed a new method of percutaneous transhepatic portal vein implantation of port-catheter system for infusion of drugs in the treatment of liver cirrhosis, with theoretical basis and the outlook of application.
文摘目的评价经皮经肝食管胃底静脉曲张栓塞术的临床应用价值. 方法肝硬化门静脉高压合并食管胃底静脉曲张破裂出血患者30例(24例为食管静脉套扎及硬化治疗术后再次出血;6例为消化道出血未行内镜治疗者).电视透视下取右腋中线或剑突下方穿刺进入门静脉分支.用弹簧钢圈、无水乙醇和明胶海绵栓塞食管胃底静脉.2例栓塞后门静脉内留置导管-药盒系统行区域性药物灌注治疗.结果 30例患者胃冠状静脉超选择插管、栓塞全部成功.胃短静脉超选择插管栓塞成功率90%.27例患者术后得到随访,随访2~18个月.17例患者术后胃镜复查显示胃底曲张静脉完全消失者13例,明显改善者4例.2例于栓塞术后1周、2个月再出血,再次栓塞后无再出血.2例门静脉留置药盒行区域性中西药物灌注者治疗后门静脉压力分别下降10 cm H2O(1 cm H2O = 0.098 kPa) 和8 cm H2O.结论经皮经肝食管胃底静脉曲张栓塞术创伤小、止血效果肯定,在急诊止血方面更具优势,应该成为门静脉高压食管胃底静脉曲张破裂出血的常规治疗方法之一.经留置药盒行门静脉区域性中西药物灌注治疗肝硬化值得进一步探讨.