Objective Our objective was to systematically evaluate the efficacy and safety of Banxia Baizhu Tianma decoction in the treatment of migraine.Methods The databases of China National Knowledge Infrastructure,VIP,WanFan...Objective Our objective was to systematically evaluate the efficacy and safety of Banxia Baizhu Tianma decoction in the treatment of migraine.Methods The databases of China National Knowledge Infrastructure,VIP,WanFang,Chinese Biomedical Databases,PubMed,and EMbase were searched by computer,and randomized controlled trials that met the inclusion criteria were retrieved.The Cochrane bias risk assessment tool was used to evaluate the quality of the included studies.RevMan 5.3 software was used to conduct meta quantitative analysis of the included studies.Results A total of 19 studies were included,with a total sample size of 1,635 cases,821 cases in the treatment group and 814 cases in the control group.The results of meta-analysis showed that(1)the clinical effective rate of the single use of Banxia Baizhu Tianma decoction or western medicine combined with Banxia Baizhu Tianma decoction in treating migraine was better than that of western medicine alone(p<0.001);(2)the improvement in cumulative number and days of vertigo in the treatment of migraine with Banxia Baizhu Tianma decoction was observed in the control group(p<0.001).TSA results showed that Z-curve passed both the traditional threshold and Trial sequential analysis(TSA)threshold.In terms of adverse reactions,55 cases were reported,including 12 cases in the treatment group and 43 cases in the control group,and no serious adverse reactions were found.Conclusion Compared with the single use of western medicine therapy,the combination of Banxia Baizhu Tianma decoction and western medicine or the single use of Banxia Baizhu Tianma decoction could better improve the effective rate and showed good safety and low incidence of adverse reactions.展开更多
Objective:To evaluate the clinical therapeutic effect of acupuncture bloodletting therapy on local swelling and pain of snakebite in the patients bitten by snakes.Methods:A total of 106 patients with trimeresurus stej...Objective:To evaluate the clinical therapeutic effect of acupuncture bloodletting therapy on local swelling and pain of snakebite in the patients bitten by snakes.Methods:A total of 106 patients with trimeresurus stejnegeri bite were randomly divided into two groups,a conventional treatment group and a conventional treatment combined with bloodletting therapy group,53 cases in each one.In the conventional treatment group,the convention treatment of western medicine was adopted.In the conventional treatment combined with bloodletting therapy group,on the base of the conventional treatment,bloodletting therapy was applied at Ashi points selected at the tender points around the wound.The intervention and observation were performed not less than 7 days in two groups.Before and after treatment,swelling and pain degrees were measured and remission time of both the limb swelling and pain were recorded in the patients.Results:Compared with the values on day 1 of treatment,swelling degree and visual analogue scale(VAS) score of the upper and lower limbs were all lower on day 3 and day 7 of treatment in the patients of the two groups(all P <0.05).Compared with the conventional treatment group,swelling degree and VAS score of the upper and lower limbs were all lower in the values of the conventional treatment combined with bloodletting therapy group on day 3 and day 7 of treatment respectively(all P <0.05).The remission time of either limb swelling or pain in the patients of the conventional treatment combined with bloodletting therapy group was shorter than the conventional treatment group respectively(both P <0.05).Conclusion:Acupuncture bloodletting therapy can effectively relieve the local swelling and pain caused by snakebite,promote the recovery of limb function,shorten the treatment course and improve the clinical therapeutic effect.展开更多
基金Shenzhen“Three Top Medical and Health Projects”(SZZYSM 202111011)Shenzhen Science and Technology Planning Project(JCYJ20180302173504891,JCYJ20190812161807600).
文摘Objective Our objective was to systematically evaluate the efficacy and safety of Banxia Baizhu Tianma decoction in the treatment of migraine.Methods The databases of China National Knowledge Infrastructure,VIP,WanFang,Chinese Biomedical Databases,PubMed,and EMbase were searched by computer,and randomized controlled trials that met the inclusion criteria were retrieved.The Cochrane bias risk assessment tool was used to evaluate the quality of the included studies.RevMan 5.3 software was used to conduct meta quantitative analysis of the included studies.Results A total of 19 studies were included,with a total sample size of 1,635 cases,821 cases in the treatment group and 814 cases in the control group.The results of meta-analysis showed that(1)the clinical effective rate of the single use of Banxia Baizhu Tianma decoction or western medicine combined with Banxia Baizhu Tianma decoction in treating migraine was better than that of western medicine alone(p<0.001);(2)the improvement in cumulative number and days of vertigo in the treatment of migraine with Banxia Baizhu Tianma decoction was observed in the control group(p<0.001).TSA results showed that Z-curve passed both the traditional threshold and Trial sequential analysis(TSA)threshold.In terms of adverse reactions,55 cases were reported,including 12 cases in the treatment group and 43 cases in the control group,and no serious adverse reactions were found.Conclusion Compared with the single use of western medicine therapy,the combination of Banxia Baizhu Tianma decoction and western medicine or the single use of Banxia Baizhu Tianma decoction could better improve the effective rate and showed good safety and low incidence of adverse reactions.
基金Supported by Shenzhen Health and Family Planning System Research:NO.SZFZ2018012。
文摘Objective:To evaluate the clinical therapeutic effect of acupuncture bloodletting therapy on local swelling and pain of snakebite in the patients bitten by snakes.Methods:A total of 106 patients with trimeresurus stejnegeri bite were randomly divided into two groups,a conventional treatment group and a conventional treatment combined with bloodletting therapy group,53 cases in each one.In the conventional treatment group,the convention treatment of western medicine was adopted.In the conventional treatment combined with bloodletting therapy group,on the base of the conventional treatment,bloodletting therapy was applied at Ashi points selected at the tender points around the wound.The intervention and observation were performed not less than 7 days in two groups.Before and after treatment,swelling and pain degrees were measured and remission time of both the limb swelling and pain were recorded in the patients.Results:Compared with the values on day 1 of treatment,swelling degree and visual analogue scale(VAS) score of the upper and lower limbs were all lower on day 3 and day 7 of treatment in the patients of the two groups(all P <0.05).Compared with the conventional treatment group,swelling degree and VAS score of the upper and lower limbs were all lower in the values of the conventional treatment combined with bloodletting therapy group on day 3 and day 7 of treatment respectively(all P <0.05).The remission time of either limb swelling or pain in the patients of the conventional treatment combined with bloodletting therapy group was shorter than the conventional treatment group respectively(both P <0.05).Conclusion:Acupuncture bloodletting therapy can effectively relieve the local swelling and pain caused by snakebite,promote the recovery of limb function,shorten the treatment course and improve the clinical therapeutic effect.