Objective To evaluate the difference between Baishao(Paeoniae Radix Alba,PRA)and Chishao(Paeoniae Radix Rubra,PRR)from different regions based on the characteristic spectra of amino acids(AAs).Methods Fingerprints of ...Objective To evaluate the difference between Baishao(Paeoniae Radix Alba,PRA)and Chishao(Paeoniae Radix Rubra,PRR)from different regions based on the characteristic spectra of amino acids(AAs).Methods Fingerprints of the 21 standard AAs were established using O-phthalaldehyde-9-fluorenylmethyl chloroformate(OPA-FMOC)pre-column derivation method.The AA components in PRA and PRR were characterized qualitatively and quantitatively,and different AAs were screened using pattern recognition technology.Results Twelve AAs were identified in both PRA and PRR.Meanwhile,aspartic acid,glutamic acid,arginine,alanine,and gamma-aminobutyric acid were screened as characteristic components,and their concentrations could effectively distinguish PRA from PRR.Conclusion The established characterization method,which is based on the characteristic spectra of AAs,is accurate,efficient,and sensitive and can effectively distinguish between PRA and PRR from different producing areas,thus providing a reference for the overall characterization and evaluation of Chinese medicinal materials.展开更多
Objective:To observe the clinical therapeutic effect and safety on cancer-related fatigue(CRF)after chemotherapy treated with the reinforcing technique of acupuncture at Qihai(气海CV6),Guanyuan(关元CV4)and bilateral Z...Objective:To observe the clinical therapeutic effect and safety on cancer-related fatigue(CRF)after chemotherapy treated with the reinforcing technique of acupuncture at Qihai(气海CV6),Guanyuan(关元CV4)and bilateral Zusanli(足三里ST36)in the patients with colorectal cancer.Methods:A total of 61 cases of CRF after chemotherapy for colorectal cancer were included in the trial and randomized into a control group(30 cases)and an observation group(31 cases).The patients of the two groups all accepted the regular chemotherapy.Each duration of chemotherapy was 3 weeks.In the observation group,8 treatments with acupuncture were combined before chemotherapy and from the day 1 to 3 of chemotherapy separately,once daily,30 min in each time,for two courses totally.Acupoints included bilateral ST36,CV6 and CV4.Separately,1 day before the first cycle of chemotherapy,1 day before the second cycle of chemotherapy and in 3 weeks after the second cycle of chemotherapy,the score of Piper fatigue scale(PFS)and the score of the scale for quality of life(QOL)were adopted to evaluate the improvement degree of cancer-related fatigue.Results:Regarding PFS score,in 3-week followup after acupuncture treatment,compared with the control group,the mean value of the score of perception dimension was reduced obviously in the acupuncture treatment group,indicating the significant difference(P<0.05).Compared with the values before treatment,after acupuncture,the mean values of the scores in behavior dimension,affection dimension,perception dimension,cognition dimension and the overall score were all reduced obviously,indicating the significant differences in the treatment group(all P<0.05).But the differences were not significant in the control group in the mean values of the scores in behavior dimension,affection dimension,perception dimension and cognition dimension as well as in the overall score(all P>0.05).Regarding the score of QOL scale,compared with the control group,in the treatment group,the mean value of physical function score was increased significantly(P<0.05)and the mean values of the scores for overall health,fatigue and dyspnea were all reduced significantly,indicating the statistical differences(all P<0.05).Compared with the values before treatment,after treatment,the mean values of the scores for physical function,role function and social function,as well as the scores of overall health,fatigue and dyspnea were all different significantly in the treatment group(all P<0.05).But the mean values of the scores for each item as well as for overall health,fatigue and dyspnea were not different significantly in the control group(all P>0.05).Conclusion:In terms of the evaluation with PFS,acupuncture alleviates fatigue degree to the mild from the moderate in the patients with CRF,especially brings a positive effect on perception dimension,meaning the improvement of mental state.Regarding the evaluation of QOL scale,acupuncture improves overall health and physical function and alleviates fatigue and dyspnea.Acupuncture therapy has no obvious toxic side effect and achieves the definite therapeutic effect.展开更多
Ten known flavonoid C-glycosides identified as 2′′-O-β-D-glucopyranosyl isovitexin(1),spinosin(2),6′′′-acetyl spinosin(3),6′′′-p-hydroxycinnamoyl-2′′O-β-D-glucopyranosyl isovitexin(4),6′′′-p-hydroxy-cin...Ten known flavonoid C-glycosides identified as 2′′-O-β-D-glucopyranosyl isovitexin(1),spinosin(2),6′′′-acetyl spinosin(3),6′′′-p-hydroxycinnamoyl-2′′O-β-D-glucopyranosyl isovitexin(4),6′′′-p-hydroxy-cinnamoyl spinosin(5),6′′′-(E)-feruloyl O-β-Dglucopyranosyl isovitexin(6),isospinosin(7),isovitexin(8),swertisin(9),swertiajaponin(10)were purified from the seeds of Hovenia dulcis Thunb.Their structures were confirmed by spectroscopic data analysis and comparison with previous literature.All compounds were obtained from H.dulcis for the first time.展开更多
A case of the absorption of corona virus disease 2019(COVID-19)promoted by professor Xu ZOU’s acupuncture technique for"benefiting kidney and strengthening anti-pathogenic qi"is introduced.A female patient ...A case of the absorption of corona virus disease 2019(COVID-19)promoted by professor Xu ZOU’s acupuncture technique for"benefiting kidney and strengthening anti-pathogenic qi"is introduced.A female patient suffered from COVID-19,64 years old,had been treated with acupuncture and Chinese herb granules for 10 days on the base of the oral administration of moxifloxacin.In the re-examination,the chest CT image indicated that the absorption of COVID-19 was obvious as compared with before,the nucleic acid test of novel corona virus was negative and the patient narrated no obvious discomfort.Acupuncture therapy plays its active adjuvant effect in the whole process of the treatment of COVID-19.展开更多
基金We thank for the funding support from the Guangdong Provincial Key Laboratory of Chinese Medicine for Prevention and Treatment of Refractory Chronic Diseases(No.2018B030322012).
文摘Objective To evaluate the difference between Baishao(Paeoniae Radix Alba,PRA)and Chishao(Paeoniae Radix Rubra,PRR)from different regions based on the characteristic spectra of amino acids(AAs).Methods Fingerprints of the 21 standard AAs were established using O-phthalaldehyde-9-fluorenylmethyl chloroformate(OPA-FMOC)pre-column derivation method.The AA components in PRA and PRR were characterized qualitatively and quantitatively,and different AAs were screened using pattern recognition technology.Results Twelve AAs were identified in both PRA and PRR.Meanwhile,aspartic acid,glutamic acid,arginine,alanine,and gamma-aminobutyric acid were screened as characteristic components,and their concentrations could effectively distinguish PRA from PRR.Conclusion The established characterization method,which is based on the characteristic spectra of AAs,is accurate,efficient,and sensitive and can effectively distinguish between PRA and PRR from different producing areas,thus providing a reference for the overall characterization and evaluation of Chinese medicinal materials.
基金National Key Research and Development Plan:Research on academic viewpoints,characteristic diagnosis and treatment methods of the experiences of famous Chinese medicine physicians and the prevention and treatment of critical illness in eastern China:2018YFC1704102。
文摘Objective:To observe the clinical therapeutic effect and safety on cancer-related fatigue(CRF)after chemotherapy treated with the reinforcing technique of acupuncture at Qihai(气海CV6),Guanyuan(关元CV4)and bilateral Zusanli(足三里ST36)in the patients with colorectal cancer.Methods:A total of 61 cases of CRF after chemotherapy for colorectal cancer were included in the trial and randomized into a control group(30 cases)and an observation group(31 cases).The patients of the two groups all accepted the regular chemotherapy.Each duration of chemotherapy was 3 weeks.In the observation group,8 treatments with acupuncture were combined before chemotherapy and from the day 1 to 3 of chemotherapy separately,once daily,30 min in each time,for two courses totally.Acupoints included bilateral ST36,CV6 and CV4.Separately,1 day before the first cycle of chemotherapy,1 day before the second cycle of chemotherapy and in 3 weeks after the second cycle of chemotherapy,the score of Piper fatigue scale(PFS)and the score of the scale for quality of life(QOL)were adopted to evaluate the improvement degree of cancer-related fatigue.Results:Regarding PFS score,in 3-week followup after acupuncture treatment,compared with the control group,the mean value of the score of perception dimension was reduced obviously in the acupuncture treatment group,indicating the significant difference(P<0.05).Compared with the values before treatment,after acupuncture,the mean values of the scores in behavior dimension,affection dimension,perception dimension,cognition dimension and the overall score were all reduced obviously,indicating the significant differences in the treatment group(all P<0.05).But the differences were not significant in the control group in the mean values of the scores in behavior dimension,affection dimension,perception dimension and cognition dimension as well as in the overall score(all P>0.05).Regarding the score of QOL scale,compared with the control group,in the treatment group,the mean value of physical function score was increased significantly(P<0.05)and the mean values of the scores for overall health,fatigue and dyspnea were all reduced significantly,indicating the statistical differences(all P<0.05).Compared with the values before treatment,after treatment,the mean values of the scores for physical function,role function and social function,as well as the scores of overall health,fatigue and dyspnea were all different significantly in the treatment group(all P<0.05).But the mean values of the scores for each item as well as for overall health,fatigue and dyspnea were not different significantly in the control group(all P>0.05).Conclusion:In terms of the evaluation with PFS,acupuncture alleviates fatigue degree to the mild from the moderate in the patients with CRF,especially brings a positive effect on perception dimension,meaning the improvement of mental state.Regarding the evaluation of QOL scale,acupuncture improves overall health and physical function and alleviates fatigue and dyspnea.Acupuncture therapy has no obvious toxic side effect and achieves the definite therapeutic effect.
基金National Natural Science Foundation of China(Grant Nos.81703379 and U1801287)Key-Area Research and Development Program of Guangdong Province(Grant No.2020B1111110007)+3 种基金Science and Technology Planning Project of Guangdong Province(Grant No.2018B020207008)Key Laboratory Program of Guangzhou(Grant 201902010082)the Specific Research Fund for TCM Science and Technology of Guangdong Provincial Hospital of Chinese Medicine(Grant Nos.YN2016QJ05 and YN2015MS03)Key Project of High-level University Construction of Guangzhou University of Chinese Medicine(Grant No.XK2018019)。
文摘Ten known flavonoid C-glycosides identified as 2′′-O-β-D-glucopyranosyl isovitexin(1),spinosin(2),6′′′-acetyl spinosin(3),6′′′-p-hydroxycinnamoyl-2′′O-β-D-glucopyranosyl isovitexin(4),6′′′-p-hydroxy-cinnamoyl spinosin(5),6′′′-(E)-feruloyl O-β-Dglucopyranosyl isovitexin(6),isospinosin(7),isovitexin(8),swertisin(9),swertiajaponin(10)were purified from the seeds of Hovenia dulcis Thunb.Their structures were confirmed by spectroscopic data analysis and comparison with previous literature.All compounds were obtained from H.dulcis for the first time.
基金Xu ZOU studio of famous Chinese medicine physicianGuangdong province+1 种基金Pneumonia emergency research project of the prevention and treatment of COVID-19 with traditional Chinese medicinethe State Administration of Traditional Chinese Medicine。
文摘A case of the absorption of corona virus disease 2019(COVID-19)promoted by professor Xu ZOU’s acupuncture technique for"benefiting kidney and strengthening anti-pathogenic qi"is introduced.A female patient suffered from COVID-19,64 years old,had been treated with acupuncture and Chinese herb granules for 10 days on the base of the oral administration of moxifloxacin.In the re-examination,the chest CT image indicated that the absorption of COVID-19 was obvious as compared with before,the nucleic acid test of novel corona virus was negative and the patient narrated no obvious discomfort.Acupuncture therapy plays its active adjuvant effect in the whole process of the treatment of COVID-19.
