基于CiteSpace的针刀治疗腰椎间盘突出症的可视化分析

目的:本研究旨在运用文献计量学方法分析针刀治疗腰椎间盘突出症(Lumbar Disc Protrusion)的研究现状、研究热点、研究趋势。方法:通过对2000年1月至2023年12月中国知网、万方、维普三大数据库中关于针刀治疗LDH的文献进行检索整理与筛选后,通过CiteSpace6.2.R4,分析作者、机构、关键词共现、聚类、突现词,绘制知识图谱。结果:本研究共收录文献1354篇,发文量总体呈上升趋势;核心作者为郭长青;发文量最多的机构为北京中医药大学。通过对关键词的分析,炎性因子、超微针刀、超声引导等代表了新的研究趋势。结论:目前该领域研究热点从治疗方式的简单结合转向传统医学与现代科技融合发展。未来可视化的超声引导、更加精密的操作工具、多维度的疗效评价指标等可能会成为新的研究热点。Objective: The purpose of this study was to analyze the current research status, research hotspot and research trend of acupotomy treatment of lumbar disc protrusion by bibliometrics. Methods: The literature on acupotomy treatment of LDH in CNKI, Wanfang and VIP from January 2000 to December 2023 was searched, sorted and screened, and the author, institution, keyword co-occurrence, clustering and breakout words were analyzed by CiteSpace6.2.R4, and the knowledge map was constructed. Results: A total of 1354 papers were included in this study, and the number of published papers showed an increasing trend. The core author is Guo Changqing;The institution with the largest number of papers is Beijing University of Chinese Medicine, and internal cooperation is the main among the universities. Research hotspots of acupotomy treatment of lumbar disc herniation focus on treatment methods, clinical efficacy, lumbar function, etc. The research types are mainly review and clinical observation. Besides acupotomy, the treatment methods mainly include massage, traction, electroacupuncture, ozone and other combined treatment methods. Inflammatory factors, ultra-micro needle-knife, and ultrasound guidance represent new research trends since 2018. Conclusion: Before, the research focus in this field was mainly on research types and treatment methods, and the treatment methods gradually changed from simple combination to integration of traditional medicine and modern science and technology. There is a lack of high-quality clinical research and in-depth basic research in the type of research, and more standardized research in this field is still needed, and cooperation between research teams and institutions needs to be strengthened. In the future, visual ultrasound guidance, more precise operating tools, and multi-dimensional efficacy evaluation indicators may become new research hotspots.

World Federation of Acupuncture-Moxibustion Societies(WFAS)Clinical Practice Guideline on Acupuncture and Moxibustion:Migraine recommendation summaries

Clinical Practice Guideline on Acupuncture and Moxibustion:Migraine(WFAS 007.9-2023)is a clinical practice guideline officially released by the World Federation of Acupuncture-Moxibustion Societies(WFAS)on October 9,2023,and is the first international guideline on the treatment of migraine with acupuncture.This international standard was developed under the guidance of rigorous evidence-based methodology,and it contains guideline purpose,scope,applicable population,applicable settings,overview of acupuncture for migraine,guideline development process and recommendations.For promoting the understanding and application of this guideline,this article summarizes a total of 18 recommendations in order to assist clinical decisions for migraine with acupuncture.

Changed ACC-DMN functional connectivity after acupuncture with deqi for functional dyspepsia treatment

Objective:To clarify altered whole brain functional connectivity of the anterior cingulate cortex(ACC)in functional dyspepsia(FD)patients,and then to explore cerebral influence of acupuncture with deqi treating for FD.Methods:Thirty-two FD patients and 35 healthy subjects(HS)were firstly scanned by the resting-state blood oxygenation level-dependent functional magnetic resonance imaging(BOLD-fMRI)to compare differences of ACC-based functional connectivity(FC).Then 32 FD patients were randomized to receive 20 sessions’acupuncture treatment with(n=16)and without deqi(n=16),as well as underwent functional magnetic resonance imaging(fMRI)scans after treatment.After group re-division according to deqi response,changes of ACC subregions-based resting-state FC(rsFC)were compared between the actual with and without deqi group.Two seeds with bilateral of each were selected as regions of interest(ROIs)of the ACC,including two from the dorsal ACC:S2(BA24)(x=±5,y=2,z=46,r=3.5 mm)and two from the pregenual ACC:17(BA24)(x=±5,y=38,z=6,r=3.5 mm).The clinical changes of the Nepean Dyspepsia Index(NDI)that measuring symptoms and quality of life(QOL)were also used to further assess the correlation with ACC subregions rsFC in FD patients.Results:Compared to HS,FD patients showed significantly increased ACC subregions rsFC with left fusiform gyrus,temporal cortex,hippocampus(HIPP)/amygdala,temporal pole,and right INS,superior occipital gyrus,and bilateral precuneus,superior parietal lobule(SPL),and decreased rsFC with left postcentral/precentral gyrus(PoG/PrG),supplementary motor area(SMA)and right cerebellum.32 FD patients which were then re-divided into the actual deqi group(n=16)and actual without deqi group(n=16).The decrease of the NDI symptom score(pre-pos)in the actual deqi group was significantly greater than that in the actual without deqi group(P<0.05).Among the two groups,the actual deqi group showed increased ACC subregions rsFC with right SMA and bilateral PrG/PoG,and decreased rsFC with right precuneus,middle occipital gyrus,bilateral posterior cingulate cortex(PCC),HIPP/paraHIPP,angular gyrus and SPL after treatment.In addition,the changed NDI QOL scores(pre-post)of the actual deqi group was significantly positively correlated with their Fisher’s transformed Z value of the altered ACC subregion(left I7)rsFC with right SPL(r=-0.597,P=0.04<0.05,FDR corrected P>0.05).Conclusion:The results tested the hypothesis that the advantage of deqi on efficacy is related to affecting the ACC subregions rsFC.It suggested that deqi might participate in the adaptive modulation of disrupted relationship between the ACC subregions and the default mode network(DMN).

Acupuncture for insomnia attention deficit and the influence of nerve electrophysiology

Objective： To test the neural electrophysiological basis of acupuncture treatment on attention deficit of insomnia patients.Methods： Thirty insomnia attention deficit patients were enrolled as the patient group in this study, and30 normal people were collected as the normal group as the compare. In patient group, acupuncture was adopted and the acupoints were Bǎihui（百会GV20）, Shéntíng（神庭 GV24）, Sìshéncōng（四神聪 EX-HN1）,Shenmen（神门 HT7） and Sānyīnjiāo（三阴交 SP6）, even reinforcing and reducing method, once a day, 10 times as a course and totally 2 courses. There was no intervention for the normal group. Pittsburg Sleep Quality Index（PSQI） for assessing the sleep quality, Schulte grid scale and the event-related potential（ERP） for assessing the attention deficit were evaluated before the treatment, 10 days after the treatment and after the treatment. The normal group were taken evaluation at the same time point.Results： 1. PSQI. The PSQI score in the patient group before the treatment was（16.20 ±2.02） and was（4.20 ±1.64） after the treatment. The difference was statistically significant（P0.05）. The normal group was（4.00 ± 1.52） at the same point after the treatment, and the differences was not statistically significant（P〈0.05）. 2. Schulte grid scale. The Schulte grid scale rating score was decrease from（32.87 ± 6.71）s before the treatment to（12.82 ±3.40） s after the treatment, and the difference was statistically significant（P〈0.05）. The normal group was（12.29 ± 3.47） s at the same point after the treatment, and the differences was not statistically significant（P〈0.05）. 3. ERP.（1） P300： in the patient group, the latency of P3 a decreased from（316.60 ± 18.42） ms before the treatment to（300.10 ± 12.03） ms after the treatment;the latency of P3 b decreased from（328.32 士 16.32） ms before the treatment to（304.63 ± 13.248） ms after the treatment; the amplitude of P3 a increased from（5.501.16） μV before the treatment to（15.20 士 2.12）μV after the treatment; the amplitude of P3 b increased from（5.76 士 1.87） μV before the treatment to（16.76 ± 2.37） μV after the treatment, and the differences were statistically significant（all P〈0.05）.（2）CNV： in the patient group, the latency of point A decreased from（404 ±129） ms before the treatment to（369 ± 105） ms after the treatment; the latency of point C decreased from（2584 ± 563） ms before the treatment to（2308 士 369） ms after the treatment; the amplitude of A-B increased from（10.3 ±17.4）μV before the treatment to（13.7 ±24.8） μV after the treatment, and the differences were statistically significant（all P〈0.05）.Conclusion： Acupuncture can improve the sleep quality and the attention deficit condition of insomnia attention deficit patients by regulating the nerve electrophysiology of the brain.

Acupoint selection rules in acupuncture therapy for postoperative urinary retention after hemorrhoidectomy based on data mining technology

Objective:To explore the core acupoints and combination rules of acupuncture therapy for postoperative urinary retention after hemorrhoidectomy,and,further to analyze the characteristics of the prescription of acupuncture therapy for postoperative urinary retention after hemorrhoidectomy.Methods:Relevant clinical studies in seven databases were searched systematically from database inception to 1 st October 2020.Based on data mining techniques,the core acupoints,characteristics and combination rules of acupuncture therapy for postoperative urinary retention after hemorrhoidectomy were analyzed comprehensively.Statistics collected and analysis of acupoint selection included the frequency of usage of acupoints,the meridian of acupoints,the location of acupoints and the combination of acupoints.Cluster and association analysis were performed utilizing Excel 13.0 and SPSS 26.0.Results:In the 36 studies included,the most frequently adopted acupoint was Sānyīnjiāo(三阴交 SP6);the most frequently adopted meridian was the foot-taiyin spleen meridian;the most frequently involved location was the lower limbs;and the most frequently adopted combination of acupoints was SP6 and Zhōngjí(中极CV 3).Cluster analysis showed that the acupoints could be divided into three categories:the first group comprised SP6 alone;the second group included CV3,Guānyuán(关元CV4),Yīnlíngquán(阴陵泉SP9) and Zúsānlǐ(足三里ST36);and the third group included Pángguāngshū(膀胱俞BL28),Chéngshān(承山BL57),Tàichōng(太冲LR3),Zhìbiān(秩边 BL54),Tàixī(太溪KI6),Hégǔ(合谷 LI4),Xuèhǎi(血海SP10),Qìhǎi(气海CV6) and Shǔidào(水道ST28).Conclusion:It was found that acupuncture therapy for postoperative urinary retention after hemorrhoidectomy mainly follows the four characteristic rules:the selection of acupoints following the meridian,selection of acupoints at local points,selection of acupoints at distal points and selection of acupoints according to special symptoms.

Study on brain network function of the specific connection between Hégǔ(合谷LI4)and the facial-oral area

Objective:This study was designed to observe the effect of electroacupuncture at Hégǔ(合谷L14),or Hòuxī(后溪SI3) or Wàiguān(外关TE5) acupoints on the function of the brain regions of a healthy human,and to explore the neural information mechanism of a specific connection between LI4 and the facialoral area from the point of view of the brain function connection network.A further objective was to enrich knowledge of the specific connection between the body surface and the meridian route,and the specificity of acupoint effects.Methods:A total of 30 healthy volunteers were randomly assigned to LI4,SI3,and TE5 groups.The members of each group were stimulated with electroacupuncture,and their heads were scanned using fMRI.DPARSFA 2.4 and REST 1.8 software were used for data preprocessing and statistical analysis.The paired t-test was used within group and the double sample t-test was used for two-group comparisons.Results:In healthy people,left LI4 with electroacupuncture mainly caused a decrease of the functional connection of the right orofacial motor area of the brain,which remained decreased after removing the needle.When LI4 was compared with SI3 and TE5,LI4 caused a more significant decline in the functional connection of the right side of the brain during acupuncture.Conclusions:Acupuncture at LI4 has a significant effect on the function of the face-and mouth-related areas in the brain,and there is a continuous effect.It is suggested that LI4 and the face and mouth have a specific relationship in the brain,which is most obvious during acupuncture.

The meridian distribution on the lacquer figure unearthed in the Han dynasty tomb in Chengdu Laoguan mountain

In 2012,a lacquer figure was unearthed from the Han dynasty tomb(188 BC-87 BC) at Chengdu Laoguanshan.The lines intaglioed on the Laoguan mountain lacquer figure were similar to the meridians.Objective:To investigate the relationship between the lines on this Laoguanshan lacquer figure and the regular meridians so as to explore the development of meridian system in ancient China.Methods:Based on collecting the photos of the Laoguan mountain lacquer figure and the representative acupuncture classics,the double evidence method(combining the unearthed relics/literature and extant literature) was performed to investigate the relationship between the lines on this Laoguanshan lacquer figure and the regular meridians.Furthermore,the development of regular meridians theory was analyzed from the number,distribution,direction and branches.Results:The routes of the 28 longitudinal white lines on the Laoguan mountain lacquer figure are similar to the regular meridians in the ancient literature including Huángdì Nèijīng 《黄帝内经》 Yellow Emperor’s Inner Classic).The number,distribution and branches of the meridians intaglioed on the Laoguanshan lacquer figure suggested the evolution of the regular-meridian system from the eleven-meridian system to the twelve-meridian system.Conclusions:The meridian system of Laoguanshan lacquer figure was a link connecting the preceding and the following.The Laoguanshan lacquer figure played an important role in the development of the early meridian theory.

A case on acupuncture for Wilson disease

Wilson disease(WD),an autosomal recessive disease with abnormal copper metabolism,is caused by mutations in the ATP7 B gene.The symptoms are characterized by liver,nervous system,and ocular manifestations related to the deposition of copper in the liver,lens nucleus,and cornea.The case reported in this article was a 30-year-old woman with high muscle tension,unable to stand or walk,low voice,and short-term memory loss.Brain MRI showed that patchy Tl,long T2 signals,and high FLAIR presented signals in the basal ganglia thalamus area,subcortex,and brain stem.Low signal shadows were presented in magnetically sensitive bilateral basal ganglia region,callus,and cerebellar dentate nucleus.Ceruloplasmin was significantly reduced.With conventional treatments by western medicine,the symptoms were not alleviated.However,after the application of acupuncture-assisted treatment,the patient is capable with self-care ability,thus a desired effect was achieved.It is therefore suggested that acupuncture shall be applied to assist the treatment of WD to relieve symptoms and help patients regain self-care ability.