甘草酸二铵对动物静脉血栓形成及凝血时间的影响

目的 :研究甘草酸二铵 (diammoniumglycyrrnizinate ,DG)对实验动物静脉血栓形成及凝血时间的影响 ;方法 :给家兔耳缘静脉、大白鼠颈外静脉及小白鼠尾静脉注射DG 10～ 2 0mg·kg 1 ,静脉注射 3 0min后 ,观察其对动物体外血栓形成及凝血时间的影响。结果 :10～ 2 0mg·kg 1 的DG对大白鼠体外血栓形成有抑制作用 ,抑制率分别为 68.7%,72 .5 %;对家兔体外血栓形成有抑制的作用 ,抑制率分别为 12 .7%,2 6.7%;对小白鼠体外凝血时间有延长作用 ,与 0 .9%氯化钠注射液比较差异有极显著性 (P <0 .0 1)。结论 :10～ 2 0mg·kg 1 DG对家兔、大白鼠体外血栓形成有抑制作用 ,对小白鼠凝血时间有延长作用。

甘露醇对动物静脉血栓形成及凝血时间的影响

目的 :研究甘露醇对动物实验性血栓形成及凝血时间的影响 ;方法 :给大白鼠颈外静脉、家兔耳缘静脉及小白鼠尾静脉注射 10 %～ 2 0 %甘露醇 10 0～ 2 0 0mg·kg-1,观察其对动物体外血栓形成及凝血时间的影响。结果 :2 0 %甘露醇2 0 0mg·kg-1对大白鼠、家兔体外血栓形成有促进的作用 ,促进率分别为 30 .6 % ,31.5 % ;10 %甘露醇对大白鼠和家兔体外血栓形成几乎无促进作用 ,与生理盐水比较差异无显著性 (P >0 .0 5 ) ;10 %～ 2 0 %甘露醇 10 0～ 2 0 0mg·kg-1对小白鼠体外凝血时间具有缩短作用 ,与生理盐水比较差异有显著性 (P <0 .0 5 )。结论 :2 0 %甘露醇 2 0 0mg·kg-1对大白鼠和家兔体外血栓形成有弱的促进作用 。

土牛膝抗炎作用的量效关系

To study the injection of Aasperal of Hubei produced, to struggle agaisnst inflammation of dose-response relationship. Methods Constantly poured kinds consistency of Aasperal down the stomach on the mice and rats. (per 100ml tach contain 2.5g,5g, 10g,20g,40g) twice a day,three consecutive days, At the three day, After poured stomach an hour. To use each grow of swelling feet rat and swelling tars of mice. To observe and take notes of kinds eonsiteney Aasperal of struggle against inflammation. Results Aasperal of Hubei produced existing to rely on dose-response relationship.

细菌性阴道病

引言 细菌性阴道病(Bacterial Vaginosis,BV)是与阴道菌丛微生态相关常见传染性非炎症综合征,属于性传播疾病的一种[1].可引发妊娠期、产褥期并发症及新生儿感染性疾病[2].

不同剂量东莨菪碱对动物静脉血栓形成的影响

To study effeet of scopolamine on the activity of the formation of throumbus outside of rabbits and mice. Methods The injection of 0.025mg·0.05mg·0.15mg scopolamine was performed on rabbits and mice. After 30 minuters, to observe the effect scopolamine of thrombus outside the animals. Results 0.025mg·0.05mg·0.15mg·kg^-1 scopolamine have restrained the thrombus of rabbits and mice in outside. The restrained rate of rabbits and mice were 68.04% ,78.35%, 81.44% and 68.7% ,72.5% ,75.53%. Compared with 0.9% sodium chloride it had obsolute discrepancy (P < 0.05).The more dose the more action. Conclusion The different dose scopolamine had restrained formation thrombus outside of rabbits and mice displayed that it had dose - response relationship.