Correlation Between Granulomatous Mastitis and Autoimmune Function and the Immuneregulating Role of Traditional Chinese Medicine

Granulomatous mastitis(GM)is a benign granulomatous condition,and its pathogenesis may be related to autoimmune disorders.Cellular immunity,humoral immunity,immunoglobulins,and complement could all play a role in the disease process,showing certain clinical patterns.Corticosteroids can quickly control disease progression,and immunosuppressants can be used for complex and refractory GM cases.In traditional Chinese medicine(TCM),“healthy qi”is similar to immune system function.For GM with deficient healthy qi,TCM treatments such as internal and external herbal applications can help regulate immune function and shorten disease duration by staged and TCM treatment,regulating viscera,reinforcing healthy qi,and eliminating pathogenic factors.

Meta-analysis of TCM in the Treatment of AIDS Diarrhea

Objective The aim of the study is to systematically evaluate the effect of Traditional Chinese medicine(TCM)in the treatment of AIDS diarrhea.Methods The computer system was used to comprehensively search database of Wanfang(WF),VIP,and China National Knowledge Infrastructure(CNKI)for relevant literature on the application effect of Chinese medicine in the treatment of AIDs diarrhea.The retrieval time was set from January 1,2010 to August 15,2021.The documents that did not meet the inclusion criteria were eliminated,and the quality of the qualified literature was evaluated according to the improved Jadad scoring standard.The main outcome indicators were entered into the literature,and Review Manager 5.0 software was used for meta-analysis.Results Eight eligible articles were included,a total of 536 cases of AIDS diarrhea patients were included.All eight eligible articles observed the clinical efficacy of TCM in the treatment of AIDS diarrhea,among which four observed the TCM syndrome changes in the treatment of AIDS diarrhea,and four observed adverse reactions of TCM in the treatment of AIDS diarrhea.All articles were extracted for valid data.After entering all the main observation index data,the results of meta-analysis showed that the effect of TCM in the treatment of AIDS diarrhea was better,the differencewas statistically significant[MD=2.92,95%CI(1.81,4.70),p<0.001];TCM in the treatment of AIDS diarrhea was more conducive to improving the TCM syndrome scores of patients,the difference was statistically significant[MD=-2.55,95%CI(-3.37,-1.73),p<0.001];the adverse effects of TCM in the treatment of AIDS diarrhea were mild,and the difference was statistically significant[MD=1.70,95%Cl(0.48,5.97),p=0.41].Conclusion The effect of TCM in the treatment of AIDS diarrhea patients is remarkable,which can effectively improve the TCM symptom scores of patients without increasing the incidence of adverse reactions.

A Brief Review of Animal Models for COVID-19

Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)causes an outbreak of corona virus disease 2019(COVID-19)globally.It is to date one of the biggest public health threat in the world.Although studies on this emerging coronavirus have developed rapidly since the COVID-19 case was confirmed,there is much remains unknown about SARS-CoV-2.To better understand the mechanism of cross-species transmission and search for efficient vaccines and therapeutics for COVID-19,animal models are highly required to evaluate countermeasures against emerging COVID-19.An ideal animal model should respond as similar as human be-ings to SARS-CoV-2 infection and show analogical symptoms,reflecting the human beings clinical sign,viral replication,and pathology that can be applied to identify in human beings.Fortunately,several animal models have been developed to study SARS-CoV-2 and aim to find new vaccines,antiviral agents,and Chinese materia medica very shortly.We aim to review the climical presentations of COVID-19 concerning pathologic features in humans and summarize the current animal models'strengths and limitations of use for SARS-CoV-2.

Systematic Arrangement and Mechanism Exploration of Clinical Suitable Diseases Treated by Thumb-Tack Acupuncture

Objective:To sort out and analyze the domestic and foreign literature on thumb-tack acupuncture in the past fifteen years using bibliometrics methods,summarize the dominant diseases of thumb-tack acupuneture,explore the mechanism of thumb-tack acupuncture and further the researches of this therapy.It is expected to provide references for policy formulations of current and future development,research hotspots and selection of scientific research topics of thumb-tack acupuncture.Methods:China National Knowledge Infrastructure(CNKI),VIP,Chinese Biomedical Literature(CBM)and PubMed were retrieved by computer,and the literature retrieval results were imported into NoteExpress 3.2 software for mana gement.Then,according to the literature inclusion criteria,the literature that met the standard was included,and the literature results were extracted and statistically analyzed by Excel.Results:Through the integration of 559 Chinese and English papers that met the standards,it was found that the thumb-tack acupuncture was suitable for mental behavior disorder system disea-ses,musculoskeletal connctive tissue diseases,neurological diseases,and genitourinary system diseases;insomnia and herpes zoster were the dominant diseases,and through mec hanism exploration,it was found that there was 8 corresponding relationship with the dominant system diseases in the disease spectrum.Conclusion:The thumb-tack acupuncture has the advantages of solid theoretical basis,definite climical curative effect,wide range of ap-plication and large application area.The current and future researches may require further explorations in the basic experimental studies of the mechanism,clinical contraindications,interdisciplinary researches,improvement of the equipments and standardized clinical operation techniques of thumb-tack acupuncture.

多元化职业防护强化教育对降低护理实习生针刺伤临床研究

目的 探讨多元化职业防护强化教育对降低护理实习生针刺伤的临床研究,为临床护理带教提供参考依据.方法 选择2013 年至2014 年在我院实习的大专以上的实习生80 人作为常规组,2014 年至2015 年在我院实习的大专以上的实习生102 人作为强化组,分析两组经过培训后发生针刺伤的差异.结果 实习结束后,两组护生实习期间发生针刺伤的人数有统计学意义（P〈 0.05）,两组护生实习期间发生针刺伤后采取正确处理流程的人数有统计学意义（P 〈 0.05）.结论 实习护生是职业暴露的高危人群,多元化职业防护教育可以增加学生对职业防护的意识,认识到职业暴露的危害性,减少职业暴露的发生.

Outcome measures in clinical trials of traditional Chinese medicine for stable angina pectoris

Objective:This work aimed to present a descriptive analysis of the outcome measures used in clinical trials of traditional Chinese medicine(TCM)for patients with stable angina pectoris,and to provide baseline data for the development of core outcome sets(COSs)for relevant clinical trials.Methods:Medical databases were searched to identify randomized trials of the effects of TCM for the treatment of stable angina pectoris.Outcome measures of each trial were extracted.Descriptive statistics were used to analyze the baseline characteristics of outcomes in clinical trials of TCM.Results:94 randomized trials(with 9,111 participants)involving 79 different outcomes were identified.The mean number of outcomes was 5(1-21 per trial).The 5 most commonly reported outcomes were efficacy rate of electrocardiogram,efficacy rate of angina pectoris,efficacy rate of TCM syndrome,fasting lipid indices,and withdrawal rate of nitroglycerin.Several challenges were identified:(1)significant heterogeneity of outcomes and differences in the technique and timing of the measurement of the same outcome;(2)transformation of continuous data into categorical data and presented as such in>90% of trials;(3)few trials on the outcomes associated with the advantages and characteristics of TCM;and(4)selective reporting of outcomes.Conclusions:The outcomes used are excessively heterogenous,and the choice of some outcomes(timing and techniques)for measurement is confusing or inappropriate.Hence,developing and implementing a COS is necessary for greater consistency.

胰十二指肠肿瘤围手术期观察及护理

近年来, 胰十二指肠的发病率逐年上升, 已成为我国人口死亡的十大恶性肿瘤之一. 根治性手术切除是目前治疗胰十二指肠肿瘤唯一有效方法.患者全身情况差、 手术范围大、 并发症多、 危险性大.为此, 加强围手术期的治疗与护理技术对提高手术成功率、 减少并发症和死亡率, 极为重要.

Potential Mechanisms of Yanghe Decoction in the Treatment of Soft Tissue Sarcoma and Arteriosclerosis Obliterans Based on Network Pharmacology

Objective The objective of this study was to investigate potential mechanisms of Yanghe Decoction(YHD)in treating soft tissue sarcoma(STS)and arteriosclerosis obliterans(ASO)based on the use of network pharmacology.Methods Candidate compounds and potential targets were identifed through the TCM Systems Pharmacology database and a comprehensive literature search.Related targets of STS and ASO were collected in the GeneCards database,DisGeNET database,and Drugbank database.Furthermore,The STRING 11.0 database was used to determine protein-protein interaction(PPI)networks;common targets were obtained and imported into Cytoscape 3.7.2.Then,a PPI network comprising common targets was drawn,and network topology analysis was performed to screen for key shared targets.Gene ontology functional enrichment analysis and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis of key shared targets were performed by using Metascape software.Subsequently.a compound-target-pathway network was constructed via Cytoscape 3.7.2.Results The following signaling pathways were found to be associated with the mechanisms of YHD in treating STS and ASO:AGE-RAGE signaling pathway,IL-17 signaling pathway;HIF-1 signaling pathway,TNF signaling pathway,interactions between cytokines and cytokine receptors,Th17 cell differentiation,and NOD-like receptor signaling pathway.Among the compounds and targets involved in these pathways,quercetin,luteolin,and kaempferol were found to be core compounds,and TNF,IL-6,and MAPK1 were found to be core targets.Conclusion Taken together,our findings elucidated that potential mechanisms of YHD in treating STS and ASO involved cellular proliferation/differentiation,angiogen-esis,inflammation,immune responses,oxidative stress,and other related signaling pathways.

Analysis of ZHENG Yuling's Medication Rules in the Syndrome Differentiation and Treatment of Cervical Cancer

Objective:To analyze the medication rules of ZHENG Yuling in the treatment of cervical cancer,and provide a basis for the clinical practice of Chinese medicine for the treatment of cervical cancer.Methods:The data of patients with cervical cancer treated by ZHENG Yuling in the First Hospital Affliated to Henan Univer-sity of Chinese Medicine from March 26,2017 to January 5,2021 were collected and the medication rules were analyzed.Results:Totally 143 cases were included,and the most frequently used prescriptions were Wuling Powder(五苓散),Simiao Powder(四妙散),Danggui Shaoyao Powder(当归芍药散),Shuyu Pill(薯损丸),Qingxin Lianzi Decoetion(清心莲子饮),Bazhen Decoction(八珍汤),etc.With statistics of the efficacy,all Chinese materia medica were divided into 19 categories,and their properties were mainly warm,mild and cold;the flavors of medicine were mainly sweet,pungent and bitter;the meridian tropism mainly ineludes the lung,liver,spleen and stomach.After cluster analysis and factor analysis,15 common factors were extracted;through the analysis of association rules,14 groups of Chinese materia medica combinations with high frequency associ-ation strength were obtai ned.Conclusion:ZHENG Yuling believes that the pathogenesis of cervical cancer is not only related to disorder between Chong and conception Channels due to the intermingling of dampness,tox-icity,blood stasis,and phlegm but also retention of urine due to qi stagnation and water retention.The direct disease location is in the uterus and indirect location may involve the lung,liver,spleen and kidney according to the development of disease,accompanying symptoms and the different constitutions of the patients.It is advo-cated that attention should be paid to not only removing dampness,detoxification,removing blood stasis,and re-ducing phlegm,but also regulating qi,opening the blockage,promoting water flow.At the same time,the spleen and stomach should be protected,and tonification and purgation should be applied in combination.

Clinical Effects of Bushen Culuan Prescription on Infertility Due to Decreased Ovarian Reserve of Kidney Deficiency and Liver Depression Pattern

Objective The objective of this study was to explore the clinical effects of Bushen Culuan prescription on infertility due to decreased ovarian reserve of kidney deficiency and liver depression pattern.Methods Totally 100 infertile patients with ovarian hypofunction treated from October 2019 to January 2022 were selected and divided into the observation group and the control group by a random number table.The control group was treated with estrogen sequential therapy,and the observation group was treated with Bushen Culuan prescription.The clinical efficacy,sex hormone levels including(follicle-stimulating hormone[FSH],luteinizing hormone[LH],and estradiol[E_(2)]),ovarian function,ovarian blood flow status(peak systolic velocity[PSV],antral follicle count[AFC],arterial pulse index[PI],and resistance index[RI]),and pregnancy outcome in the two groups were compared and analyzed.Results The total effective rate of the observation group(96.00%)was significantly higher than that of the control group(80.00%).The difference was statistically significant(p<0.05).Before treatment,there was no significant difference in sex hormone levels(FSH,LH,E_(2),and FSH/LH),ovarian function(number of primary follicles,number of dominant follicles,ovulation number,and endometrial thickness),and ovarian blood flow(PSV,RI,PI,and AFC)between the two groups(p>0.05).After treatment,the levels of serum hormones FSH,LH,E_(2),and FSH/LH decreased significantly in both groups.The number of primary follicles,dominant follicles,and ovulation increased significantly,and the thickness of endometrium decreased significantly;the indexes of PSV,RI,and AFC of ovarian blood flow increased significantly,and the PI index decreased significantly.The levels of each index in the observation group were better than those in the control group(p<0.05).In the control group,32 cases were pregnant within 1 year after treatment,and the pregnancy rate was 64.00%;21 cases in the observation group were pregnant within 1 year after treatment,and the pregnancy rate was 42.00%;the pregnancy rate in the observation group was higher than that in the control group,and the difference was statistically significant(χ^(2)=4.014,p=0.045<0.05).Conclusion Bushen Culuan prescription has a definite effect on infertility due to ovarian hypofunction.The action mechanism may involve multicomponent and multitarget stimulation to improve patients'ovarian function,regulate the level of sex hormones,and improve the pregnancy outcome.

Rupi Sanjie Xiaotong Plaster in Treating Breast Hyperplasia of Liver Stagnation and Phlegm Coagulation Pattern

Objective:To observe the clinical efcacy and safety of external application of Rupi Sanjie Xiaotong Plaster(乳癖散结消痛膏,RPSJXTP)in treating breast hyperplasia of liver stagnation and phlegm coagulation pattern.Methods:Totally 72 female patients with breast hyperplasia of liver stagnation and phlegm coagulation pattern admitted to the First Hospital Affiliated to Henan University of Chinese Medicine were enrolled by ran-domized,single-blind,placebo-controlled research method,and were divided into the treatment group(36 ca-ses)and the control group(36 cases)according to computer random number method.The treatment group were given RPSJXTP,while the control group were gi ven placebo plaster.The course of treatment in both groups was 8 weeks.The breast pain score,breast color ultrasound score,lump score,depression score,and Chinese medicine syndrome score were compared between the two groups at different times.The levels of estra-diol(E_(2)),progesterone(P)and pituitary prolactin(PRL)were detected and the adverse reactions of two groups were observed during the treatment of both groups.Results:Before treatment,there was no significant difference in total breast pain score,breast color ultrasound score,lump score,depression score and levels of serum P,E_(2)and PRL between the two groups(P>0.05);compared with previous treatment,the total breast pain score,breast color ultrasound score,lump score,and depression score significantly decreased in the treat-ment group(P<0.05),and the total breast pain score and depression score of the control group significantly declined(P<0.05);compared with control group,the total breast pain score,breast color ultrasound score,lump score,and depression score significantly decreased after treatment in the treatment group(P<0.05).The improvement rate of Chinese medicine syndromes and the clinical efective rate in the treatment group were higher than those in the control group(P<0.05).There were no serious systemie adverse reactions during the treatment in both groups.Local pruritus occurred in 3 cases in the treatment group and 1 case in the control group.Conclusion:RPSJXTP is effective in treating breast hyperplasia of liver stagnation and phlegm coagula-tion pattern.It can effectively relieve the breast pain which will not recur after stopping of drug use,which can reduce the color ultrasound score,lump score,and depression score of the patients and improve Chinese medi-cine syndromes without serious adverse reactions.

Electroacupuncture for post-stroke anxiety disorder on the base of the heart-brain theory:A randomized controlled trial

Objective:To evaluate the differences in the clinical effect and the safety in the treatment of post-stroke anxiety disorder(PSAD)between electroacupuncture(EA)and paroxetine on the base of the heart-brain theory.Methods:A total of 70 patients of PSAD were randomized into an EA group and a medication group,35 cases in each one.In the EA group,four acupoints were selected and divided into two pairs.In the Pair A,there were Baihui(百会GV20)and Fengfu(风府GV16).In the Pair B,there were Xinshu(心俞BL15)and Shenmen(神门HT7).After acupuncture,the electroacupuncture apparatus was applied.The duration of needle retention was 20 min.EA was given three times a week,totally for 4 weeks.In the medication group,paroxetine tablets were administered orally,10 mg daily in the first 4 days and 20 mg afterwards,totally for 4 weeks.Before and after treatment,as well as in the follow-up period,Hamilton anxiety scale(HAMA),Barthel index(BI)for daily life ability,and clinical global impression(CGI)were observed and the clinical therapeutic effect was evaluated separately.Results:A total of 3 cases were dropped-out in the medication group.Finally,35 cases in the EA group and 32 cases in the medication group were included in the analysis.Compared with the scores before treatment,the scores of HAMA and CGI-SI(severity of illness)were lower and the scores of BI were higher after treatment and during the follow-up in either the EA group or the medication group(all P<0.05).Compared with the scores after treatment,the differences were not significant in HAMA and CGISI scores during the follow-up in either the EA group or the medication group(all P>0.05).Compared with the medication group,BI score in the EA group was higher in the follow-up,indicating the statistical significance(P<0.05).After treatment,CGI-SI score was different statistically between the EA group and the medication group(P<0.05).There were 5 cases with adverse reactions in the EA group and 9 cases in the medication group.Conclusions:The therapeutic effect of electroacupuncture on the base of heart-brain theory is similar to the oral administration of paroxetine in the treatment of post-stroke anxiety disorder.This therapy relieves anxious emotions,promotes the recovery of limb function and has less adverse reactions in the patients.

Changed ACC-DMN functional connectivity after acupuncture with deqi for functional dyspepsia treatment

Objective:To clarify altered whole brain functional connectivity of the anterior cingulate cortex(ACC)in functional dyspepsia(FD)patients,and then to explore cerebral influence of acupuncture with deqi treating for FD.Methods:Thirty-two FD patients and 35 healthy subjects(HS)were firstly scanned by the resting-state blood oxygenation level-dependent functional magnetic resonance imaging(BOLD-fMRI)to compare differences of ACC-based functional connectivity(FC).Then 32 FD patients were randomized to receive 20 sessions’acupuncture treatment with(n=16)and without deqi(n=16),as well as underwent functional magnetic resonance imaging(fMRI)scans after treatment.After group re-division according to deqi response,changes of ACC subregions-based resting-state FC(rsFC)were compared between the actual with and without deqi group.Two seeds with bilateral of each were selected as regions of interest(ROIs)of the ACC,including two from the dorsal ACC:S2(BA24)(x=±5,y=2,z=46,r=3.5 mm)and two from the pregenual ACC:17(BA24)(x=±5,y=38,z=6,r=3.5 mm).The clinical changes of the Nepean Dyspepsia Index(NDI)that measuring symptoms and quality of life(QOL)were also used to further assess the correlation with ACC subregions rsFC in FD patients.Results:Compared to HS,FD patients showed significantly increased ACC subregions rsFC with left fusiform gyrus,temporal cortex,hippocampus(HIPP)/amygdala,temporal pole,and right INS,superior occipital gyrus,and bilateral precuneus,superior parietal lobule(SPL),and decreased rsFC with left postcentral/precentral gyrus(PoG/PrG),supplementary motor area(SMA)and right cerebellum.32 FD patients which were then re-divided into the actual deqi group(n=16)and actual without deqi group(n=16).The decrease of the NDI symptom score(pre-pos)in the actual deqi group was significantly greater than that in the actual without deqi group(P<0.05).Among the two groups,the actual deqi group showed increased ACC subregions rsFC with right SMA and bilateral PrG/PoG,and decreased rsFC with right precuneus,middle occipital gyrus,bilateral posterior cingulate cortex(PCC),HIPP/paraHIPP,angular gyrus and SPL after treatment.In addition,the changed NDI QOL scores(pre-post)of the actual deqi group was significantly positively correlated with their Fisher’s transformed Z value of the altered ACC subregion(left I7)rsFC with right SPL(r=-0.597,P=0.04<0.05,FDR corrected P>0.05).Conclusion:The results tested the hypothesis that the advantage of deqi on efficacy is related to affecting the ACC subregions rsFC.It suggested that deqi might participate in the adaptive modulation of disrupted relationship between the ACC subregions and the default mode network(DMN).

Moxibustion versus non-moxibustion for immune reconstitution inflammatory syndrome in patients with HIV:A 48-week prospective cohort study

Objective:To assess the effects of moxibustion on immune reconstitution inflammatory syndrome(IRIS)in patients with acquired immune deficiency syndrome(AIDS)by tracking T-cell subsets over a 48-week prospective cohort study.Methods:Patients with AIDS who had low viral loads and weakened immune systems were divided into a moxibustion group and a non-moxibustion group.The non-moxibustion group received standard western treatment,including 48 weeks of antiretroviral therapy(ART).The moxibustion group received ART combined with moxibusion therapy,administered three times weekly.Each treatment lasted 10 weeks,with four courses completed over 48 weeks,separated by 2-week breaks.At different time points,plasma levels of CD4^(+),CD8^(+),CD45RAt,CD45RO^(+),CD4^(+)CD28^(+),CD8^(+)CD38^(+),and CD4^(+)CD38^(+)were compared between the two groups.Results:A total of 200 eligible patients were included and divided into two groups,with 100 in the non-moxibustion group and 100 in the moxibustion group.At Week 24,the CD4^(+)T cell count was(180.71±79.62)cells/μL in the non-moxibustion group and(218.22±82.02)cells/μL in the moxibustion group.By Week 36,the counts were(204.83±96.78)cells/μuL and(239.35±81.90)cells/μL,respectively.At Weeks 24 and 48,the CD8^(+)T cell and CD45RO^(+)counts were higher in the moxibustion group than in the non-moxibustion group(P<0.05).By Week 48,the CD45RA^(+)count was also higher in the moxibustion group(P<0.05).At Week 24,the CD4^(+)CD25^(+)count was lower in the moxibustion group than in the non-moxibustion group(P<0.05).

Two proved cases of treating herpes zoster pain by needling wei

Two cases of herpes zoster neuralgia treated by shallow needling combined with electroacupuncture were introduced. The literature basis and possible mechanisms were discussed.

The meridian distribution on the lacquer figure unearthed in the Han dynasty tomb in Chengdu Laoguan mountain

In 2012,a lacquer figure was unearthed from the Han dynasty tomb(188 BC-87 BC) at Chengdu Laoguanshan.The lines intaglioed on the Laoguan mountain lacquer figure were similar to the meridians.Objective:To investigate the relationship between the lines on this Laoguanshan lacquer figure and the regular meridians so as to explore the development of meridian system in ancient China.Methods:Based on collecting the photos of the Laoguan mountain lacquer figure and the representative acupuncture classics,the double evidence method(combining the unearthed relics/literature and extant literature) was performed to investigate the relationship between the lines on this Laoguanshan lacquer figure and the regular meridians.Furthermore,the development of regular meridians theory was analyzed from the number,distribution,direction and branches.Results:The routes of the 28 longitudinal white lines on the Laoguan mountain lacquer figure are similar to the regular meridians in the ancient literature including Huángdì Nèijīng 《黄帝内经》 Yellow Emperor’s Inner Classic).The number,distribution and branches of the meridians intaglioed on the Laoguanshan lacquer figure suggested the evolution of the regular-meridian system from the eleven-meridian system to the twelve-meridian system.Conclusions:The meridian system of Laoguanshan lacquer figure was a link connecting the preceding and the following.The Laoguanshan lacquer figure played an important role in the development of the early meridian theory.

Case of multiple verruca plantaris

A female student,23 years old,suffering from multiple warts scattered on the right sole for 2 years and pain on the bottom of the first metatarsal bone when walking for 1 month.The case was diagnosed as kujinjian(枯筋箭)in traditional Chinese medicine and verruca plantaris in western medicine.At the beginning of treatment,fire needling therapy was applied to local lesions,once every two days.Afterwards,moxibustion with moxa cone was used at the local lesions,once a day,three cones on each lesion till warts were dropped.Simultaneously,in combination,mild moxibustion was given at bilateral Zusanli(足三里ST36)for 15 min,once a day.After three times of moxibustion therapy,a part of warts were crusted and 3 weeks later,all the warts were dropped.No recurrence was found in the follow-up visit.The therapeutic methods of this case are simple in manipulation and satisfactory in therapeutic effect.

Case report of seborrheic dermatitis

One case of seborrheic dermatitis,male patient,aged 73 years is reported.After treated with acupuncture,penetrating moxibustion and bloodletting therapies,skin lesions on the neck and shoulder regions disappeared,the epidermis returned to normal and itching disappeared.There was no recurrence in the follow-up visit 3 months later.Hence,acupuncture,combined with penetrating moxibustion and bloodletting has a definite effect on this case in the patient and it is worthy of promotion and application in clinical practice.

Different acupuncture modalities for 90 cases of adhesive capsulitis at different clinical stages

Objective:To observe the clinical efficacy of different acupuncture modalities in the treatment of adhesive capsulitis a tthrough different clinical stages.Methods:Ninety patients of adhesive capsulitis weregraded in three different stages based on clinical presentations.Patients in painful stage were treated with silver needles once every 5 to 7 days for two courses;patients in adhesive stage were given acupotomy treatment every 7 to 10 days for two courses;while patients in recovery stage were treated with acupuncture with warm needles by moxibustion on tendon knots,once a day 10 times in a course,for two courses of treatment.The disease scores were compared between all groups before and after the treatment,and clinical efficacy was evaluated after the treatment.Results:The disease scores in patients of all three stages were higher after treatment,and the differences were statistically significant(all P<0.05).Among 90 patients with adhesive capsulitis,32 cases were clinically under controlled,37 cases claimed remarkably effective,18 were effective,and 3 ineffective cases,thus the total effective rate for this stage-based treatment is 96.7%.Conclusion:For adhesive capsulitis,different acupuncture modalities targeting patients in different clinical stages were feasible and effective,the disease scores of patients were significantly improved.

Cases on the clinical application of needling wei method

In the paper,two medical cases,i.e.carpal tunnel syndrome and acute chest soft tissue contusion,are treated and reported with acupuncture kinesitherapy,in which the needles are inserted shallowly and no sensation of deqi is required in the guidance of subcutaneous shallow puncture and"pain point as the acupoint".The mechanism of needling wei method is summarized.