The respiratory motion leads to significant motion artifacts of the positron emission tomography （PET） image, thus influencing diagnoses and treatments in the radiation oneology. The existing approaches to correct...The respiratory motion leads to significant motion artifacts of the positron emission tomography （PET） image, thus influencing diagnoses and treatments in the radiation oneology. The existing approaches to correct motion artifacts involve using gating devices and/or four-dimensional （4-D） computed tomography （CT）. However, they have the disadvantages of high CT dose and high computational burden. Hence, a sinusoid vibration model is presented to simulate the respiratory motion. The motion extent and the direction are derived from the Radon transform of the cepstrum of the blurred image. Then, two typical deeonvolution algorithms, i.e. , Wiener filter （WF） and the Richardson-Lucy （RL） algorithms are used to eliminate the motion blur according to the estimated parameters and their de-blurring results are compared. Experiments on both synthetic and phantom images show good performance of the presented model for identifying vibration modeled respiration motion and reducing the motion blur. The method has advantages of safety, convenience, and economy. And it is promising to correct the motion artifacts of the non-gated PET image.展开更多
目的探讨含斑块内出血(IPH)的单、双侧颈动脉斑块患者斑块易损性的差异。方法回顾性分析2009年12月~2012年12月间来我院行颈动脉高分辨磁共振检查的患者,其中44例患者显示颈动脉粥样硬化斑块存在IPH。将患者按单、双侧IPH分为两组。比...目的探讨含斑块内出血(IPH)的单、双侧颈动脉斑块患者斑块易损性的差异。方法回顾性分析2009年12月~2012年12月间来我院行颈动脉高分辨磁共振检查的患者,其中44例患者显示颈动脉粥样硬化斑块存在IPH。将患者按单、双侧IPH分为两组。比较两组间患者的年龄、斑块最大管壁厚度和纤维帽破裂发生率的差异性。结果双侧IPH组患者的年龄(66.6±9.4岁vs 73.7±9.0岁,P=0.027)、最大斑块厚度(6.3±1.9 mm vs 5.0±1.3 mm,P=0.035)和溃疡的发生率(50%vs 13.3%,P=0.025)明显高于单侧IPH组患者。Logistic回归分析发现,双侧IPH与溃疡的发生具有明显的相关性(OR=6.5,95%CI 1.5~28.7,P=0.014),模型1校正性别后,两者仍具有显著相关性(OR=5.7,95%CI 1.1~29.2,P=0.036)。然而,模型2中额外校正年龄(P=0.131)或最大斑块厚度(P=0.139)后,双侧IPH与溃疡的发生不具有显著相关性。结论与单侧IPH患者相比,双侧IPH患者的年龄较轻、斑块负荷更重、溃疡发生率更高。双侧IPH患者的斑块易损性明显重于单侧IPH患者,需要临床加以关注。展开更多
基金Supported by the Science and Technology Foundation of Guangdong Province(2008B030303055)~~
文摘The respiratory motion leads to significant motion artifacts of the positron emission tomography （PET） image, thus influencing diagnoses and treatments in the radiation oneology. The existing approaches to correct motion artifacts involve using gating devices and/or four-dimensional （4-D） computed tomography （CT）. However, they have the disadvantages of high CT dose and high computational burden. Hence, a sinusoid vibration model is presented to simulate the respiratory motion. The motion extent and the direction are derived from the Radon transform of the cepstrum of the blurred image. Then, two typical deeonvolution algorithms, i.e. , Wiener filter （WF） and the Richardson-Lucy （RL） algorithms are used to eliminate the motion blur according to the estimated parameters and their de-blurring results are compared. Experiments on both synthetic and phantom images show good performance of the presented model for identifying vibration modeled respiration motion and reducing the motion blur. The method has advantages of safety, convenience, and economy. And it is promising to correct the motion artifacts of the non-gated PET image.
文摘目的探讨含斑块内出血(IPH)的单、双侧颈动脉斑块患者斑块易损性的差异。方法回顾性分析2009年12月~2012年12月间来我院行颈动脉高分辨磁共振检查的患者,其中44例患者显示颈动脉粥样硬化斑块存在IPH。将患者按单、双侧IPH分为两组。比较两组间患者的年龄、斑块最大管壁厚度和纤维帽破裂发生率的差异性。结果双侧IPH组患者的年龄(66.6±9.4岁vs 73.7±9.0岁,P=0.027)、最大斑块厚度(6.3±1.9 mm vs 5.0±1.3 mm,P=0.035)和溃疡的发生率(50%vs 13.3%,P=0.025)明显高于单侧IPH组患者。Logistic回归分析发现,双侧IPH与溃疡的发生具有明显的相关性(OR=6.5,95%CI 1.5~28.7,P=0.014),模型1校正性别后,两者仍具有显著相关性(OR=5.7,95%CI 1.1~29.2,P=0.036)。然而,模型2中额外校正年龄(P=0.131)或最大斑块厚度(P=0.139)后,双侧IPH与溃疡的发生不具有显著相关性。结论与单侧IPH患者相比,双侧IPH患者的年龄较轻、斑块负荷更重、溃疡发生率更高。双侧IPH患者的斑块易损性明显重于单侧IPH患者,需要临床加以关注。
