赋能教育联合肠内营养剂对胃癌化疗患者营养状况的影响

目的探讨赋能教育联合肠内营养剂对胃癌化疗患者营养状况的影响。方法随机抽取福建医科大学肿瘤临床医院2022年2月—2023年2月收治的100例胃癌化疗患者作为研究对象。按照护理方法不同将患者分为试验组与对照组,各50例。2组采用常规胃癌化疗,对照组给予胃癌患者肠内营养剂辅助,试验组采用赋能教育联合肠内营养剂的方法。比较2组血清蛋白水平、营养状况、不良反应发生情况、生活质量评价。结果护理后,试验组总蛋白、白蛋白、前白蛋白、血红蛋白及体质量分别为(74.82±4.21)g/L、(46.82±3.71)g/L、(4.31±0.71)g/L、(128.81±10.41)g/L、(72.12±12.17)kg,均高于对照组的(70.89±4.91)g/L、(42.91±5.10)g/L、(3.54±0.68)g/L、(122.84±8.31)g/L、(65.94±9.08)kg(P<0.05)。护理后,试验组患者主观整体评估(patient-generated subjective global assessment,PG-SGA)评分为(1.55±0.41)分,低于对照组的(3.22±0.75)分(P<0.05)。试验组不良反应总发生率为4.00%,低于对照组的26.00%(P<0.05)。护理后,试验组生活质量评分低于对照组(P<0.05)。结论胃癌化疗患者给予赋能教育联合肠内营养剂干预,能够改善血清蛋白及营养水平,提高生活质量的同时能够减少不良反应。

Isotropic volumetric MRI for displaying cranial perineural spread of cranial nerve in nasopharyngeal carcinoma

Objective To observe the value of isotropic volumetric MRI for displaying perineural spread(PNS)of cranial nerve(CN)in nasopharyngeal carcinoma.Methods Eighty-seven patients with pathologically proven nasopharyngeal carcinoma were prospectively enrolled.MR scanning,including three-dimensional liver acquisition with volume acceleration-flexible(3D LAVA_Flex)image,T2WI with fat suppression(T2WI-FS),T1WI,contrast enhancement(CE)T1WI-FS of nasopharynx and neck region were performed.The displaying rates of CN PNS were evaluated and compared between 3D LAVA_Flex and T2WI-FS,T1WI,CE-T1WI-FS at patient level,CN group level and neural level,respectively.Results The displaying rate of CN PNS in all 87 nasopharyngeal carcinoma patients by 3D LAVA_Flex sequence was 49.43%(43/87),higher than that of conventional MRI(30/87,34.48%,P=0.001).Among 59 patients with advanced nasopharyngeal carcinoma diagnosed with conventional sequences,the displaying rate of CN PNS was 71.19%(42/59)by 3D LAVA-Flex sequence,higher than that of conventional MRI(30/59,50.85%,P=0.001).At both patient level and posterior CN level,significant differences of the displaying rate of CN PNS were found between 3D LAVA-Flex sequence and T2WI-FS,T1WI,CE-T1WI-FS,while at CN level,the displaying rates of mandibular nerve PNS,CNⅨ—ⅪPNS in jugular foramen(P<0.05)and CNⅨ—ⅫPNS in carotid space of 3D LAVA_Flex sequence were all significantly higher than that of T2WI-FS,T1WI and CE-T1WI-FS(all P<0.05),of PNS of CNⅢ—Ⅴin cavernous sinus were higher than that of T2WI-FS(P<0.05),while of PNS of hypoglossal nerve were significantly higher than that of T2WI-FS and T1WI(both P<0.05).Conclusion 3D LAVA_Flex sequence could be used to effectively display CN PNS of nasopharyngeal carcinoma.

俱乐部式团队心理认知干预对白血病患者应对方式及睡眠质量的应用

目的:探究俱乐部式团队心理认知干预对白血病患者应对方式及睡眠质量的应用。方法:选取2023年3月至2024年3月泉州市第一医院收治的白血病患者110例作为研究对象,按照随机数字表法分为对照组和观察组,每组55例。对照组采取常规护理,观察组应用俱乐部式团队心理认知干预,对比2组患者护理前后应对方式、睡眠质量及不良情绪变化。结果:干预后,观察组面对、回避、屈服评分均优于对照组,差异有统计学意义(P<0.05);观察组睡眠质量评分低于对照组,差异有统计学意义(P<0.05);观察组患者焦虑、抑郁情绪均低于对照组,差异有统计学意义(P<0.05)。结论:面对白血病患者采取俱乐部式团队心理认知干预,可提高患者应对方式,改善睡眠质量及不良情绪,利于预后,值得推广采纳。