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Meta-analysis of the efficacy and safety of Huanglian Wendan Decoction alone or combined with western medicine in treating insomnia caused by phlegm-heat internal disturbance 被引量:4
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作者 YANG Lei HE Liyun +4 位作者 CHEN Xiao WANG Kaiyue FANG Yongjun LIANG Zhuang YANG Zhao 《Digital Chinese Medicine》 2022年第3期340-352,共13页
Objective To evaluate the efficacy and safety of Huanglian Wendan Decoction(黄连温胆汤,HLWDD)alone or combined with western medicine in treating insomnia caused by phlegm-heat internal disturbance in recent 10 years.M... Objective To evaluate the efficacy and safety of Huanglian Wendan Decoction(黄连温胆汤,HLWDD)alone or combined with western medicine in treating insomnia caused by phlegm-heat internal disturbance in recent 10 years.Methods The randomized controlled trials of HLWDD alone or combined with western medicine in treating insomnia caused by phlegm-heat internal disturbance from January 1,2012 to April 1,2022 were searched in China National Knowledge Infrastructure(CNKI),China Science and Technology Journal Database(VIP),Wanfang Database,China BioMedical Literature Database(CBM),PubMed,Web of Science,Embase,and Cochrane Library databases.After being screening,the included literature was analyzed to evaluate the effective rate,Pittsburgh Sleep Quality Index(PSQI)score,traditional Chinese medicine(TCM)syndrome score,and adverse reactions of HLWDD on insomnia caused by phlegm-heat internal disturbance.The subgroup analyzed the effect of HLWDD after different treatment courses,and compared the therapeutic effects of HLWDD alone and HLWDD combined with western medicine.Results Twenty-seven randomized controlled trials were finally included,with a total of 2395 patients.The results of the meta-analysis showed that the curative effect of HLWDD alone or combined with the western medicine group was better than that of the western medicine group[RR=1.14,95%CI(1.06,1.22),P=0.000].The PSQI score[SMD=-0.31,95%CI(-0.42,-0.20),P=0.000],TCM syndrome score[SMD=-0.40,95%CI(-0.67,-0.12),P=0.005],and adverse reaction rate[RR=0.21,95%CI(0.15,0.29),P=0.000]of HLWDD alone or combined with western medicine group were significantly reduced compared with the western medicine group.The subgroup’s analysis showed that the curative effect of HLWDD alone or combined with western medicine group of 4 weeks treatment course was better than that of the western medicine group[RR=1.14,95%CI(1.03,1.26),P<0.05].The TCM syndrome score of HLWDD alone or combined with the western medicine group of 4 weeks treatment course decreased more obviously than that of the western medicine group[SMD=-0.60,95%CI(-0.96,-0.25),P<0.05].There were no significant differences between HLWDD alone or combined with western medicine group and western medicine group with different treatment courses based on PSQI score and adverse reaction rate.Based on the effective rate,the comparison between the HLWDD alone group and the western medicine group[RR=1.09,95%CI(1.00,-1.20)P<0.05],and between the HLWDD combined with western medicine group and the western medicine group[RR=1.15,95%CI(1.03,1.29),P<0.05]was the same.PSQI score[SMD=-0.44,95%CI(-0.59,-0.30),P<0.05]and TCM syndrome score[SMD=-1.10,95%CI(-1.59,-0.61),P<0.05]of HLWDD combined with western medicine group were significantly lower than those of the western medicine group.There were no significant differences of adverse reaction rate between HLWDD alone group[RR=0.08,95%CI(0.04,0.17),P<0.05]and HLWDD combined with western medicine group[RR=0.36,95%CI(0.24,0.53),P<0.05].Conclusion HLWDD alone or combined with western medicine is an effective treatment for insomnia caused by phlegm-heat internal disturbance,which has a high effective rate,significantly reduced PSQI score and TCM syndrome score,and favorable safety.The best course of treatment is 4 weeks. 展开更多
关键词 Huanglian Wendan Decoction(黄连温胆汤 HLWDD) Phlegm-heat internal disturbance Western medicine INSOMNIA Curative effect META-ANALYSIS
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综合护理干预联合消木丹颗粒治疗30例单纯性脂肪肝疗效观察 被引量:2
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作者 刘宝咸 席奇 +3 位作者 南然 宋春荣 李京涛 刘亚珠 《现代中医药》 CAS 2016年第5期22-24,共3页
目的综合护理干预联合消木丹颗粒联合治疗单纯性脂肪肝患者疗效观察。方法将60例非酒精性单纯性脂肪肝患者随机分为两组,两组治疗方法均服用陕西中医药大学附属医院院内制剂消木丹颗粒,对照组采用常规护理,治疗组予以综合护理干预,疗程... 目的综合护理干预联合消木丹颗粒联合治疗单纯性脂肪肝患者疗效观察。方法将60例非酒精性单纯性脂肪肝患者随机分为两组,两组治疗方法均服用陕西中医药大学附属医院院内制剂消木丹颗粒,对照组采用常规护理,治疗组予以综合护理干预,疗程均为半年。结果治疗结束后,治疗组肝功能的改善(ALT、rGT)优于对照组,并且可以降低TG;两组均能提高肝/脾CT值,且治疗组优于对照组。结论综合护理干预联合消木丹颗粒治疗单纯性脂肪肝临床疗效显著,值得临床推广。 展开更多
关键词 综合护理干预 消木丹颗粒 单纯性脂肪肝
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针刺联合益气聪明汤治疗耳鸣耳聋临床研究 被引量:4
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作者 谭林刚 张建涛 +5 位作者 马阿苗 王卫刚 王敏 王玲 柯宗斌 周明春 《现代中医药》 CAS 2022年第1期119-122,共4页
目的观察针刺联合益气聪明汤治疗对耳鸣耳聋患者临床效果及对QOL评分的影响。方法选取2017年1月—2019年12月我院收治的耳鸣耳聋患者48例,应用数字表法将其随机分为2组,对照组进行针刺治疗,治疗组进行针刺联合益气聪明汤治疗。比较两组... 目的观察针刺联合益气聪明汤治疗对耳鸣耳聋患者临床效果及对QOL评分的影响。方法选取2017年1月—2019年12月我院收治的耳鸣耳聋患者48例,应用数字表法将其随机分为2组,对照组进行针刺治疗,治疗组进行针刺联合益气聪明汤治疗。比较两组患者治疗有效率、听力情况、症状消失时间、血液流变学情况、生活质量(QOL)。结果治疗组有效率高于对照组(P<0.05);治疗组低频区听力高于对照组(P<0.05),两组高频区听力相比,无明显差异(P>0.05);治疗组症状消失时间早于对照组(P<0.05);治疗组红细胞变形指数大于对照组(P<0.05),治疗组红细胞聚集指数、红细胞压积、血浆粘度、全血低切粘度、中切粘度、高切粘度小于对照组(P<0.05);治疗组QOL高于对照组(P<0.05)。结论耳鸣耳聋患者治疗中,针刺联合益气聪明汤治疗结果显著提高,值得临床使用。 展开更多
关键词 针刺 益气聪明汤 耳鸣耳聋 听力
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基于分组联接的Apriori算法的中医药诊疗关联性分析
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作者 李宏斌 仝武宁 《医疗卫生装备》 CAS 2017年第8期34-37,共4页
目的:高效准确地分析中医药诊疗数据之间的关联性,为科研临床研究提供依据。方法:针对中医药诊疗数据的特点,提出并设计一种改进的Apriori算法——分组联接Apriori算法,用某院中医脑病治疗数据库的数据进行关联性分析实验,以验证该算法... 目的:高效准确地分析中医药诊疗数据之间的关联性,为科研临床研究提供依据。方法:针对中医药诊疗数据的特点,提出并设计一种改进的Apriori算法——分组联接Apriori算法,用某院中医脑病治疗数据库的数据进行关联性分析实验,以验证该算法的可行性。结果:该算法对联接属性进行了分组操作,减少了大量不相关数据的联接操作,提高了算法的效率。结论:改进后分组联接Apriori算法的执行时间明显低于经典Apriori算法,该算法能够更好地为中医药诊疗数据的科研临床应用服务。 展开更多
关键词 关联规则 自然联接 分组联接 频繁项集 APRIORI算法
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Prick-bloodletting combined with cupping on the back for 52 cases of acne 被引量:1
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作者 FU Qi-fei ZHANG Qian +5 位作者 DUAN Bi-feng ZHANG Hao-bin YIN Ke-jing LI Min OU Guo-feng DING Tian-hong 《World Journal of Acupuncture-Moxibustion》 CSCD 2016年第4期61-64,共4页
Objective To introduce the experience of professor YIN Ke-jing in selecting reaction points on taiyang meridian on the back for acne. Methods Positive reaction points on taiyang meridian of the medial border of scapul... Objective To introduce the experience of professor YIN Ke-jing in selecting reaction points on taiyang meridian on the back for acne. Methods Positive reaction points on taiyang meridian of the medial border of scapulae on the both sides of the back were selected for prick-bloodletting combined with cupping, and the treatment was conducted once every three days,3 treatments as one course of treatment and 2–3 courses of treatment were needed. Results After treatment for two courses of treatment, the total effective rate of the 52 patients was 96.2%. Conclusion The application of the theory of corresponding meridian of meridians and collaterals in treatment of acne made the treatment simple and convenient; with less acupoints selected, rapid effect and definite clinical efficacy, this method is worthy of being generalized. 展开更多
关键词 ACNE positive reaction point prick-bloodletting combined with cupping
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